Luis Bujanda

Summary

Country: Spain

Publications

  1. doi request reprint Effect of aspirin and antiplatelet drugs on the outcome of the fecal immunochemical test
    Luis Bujanda
    Department of Gastroenterology, Hospital Donostia, Instituto Biodonostia, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, Universidad del Pais Vasco, San Sebastian, Spain Electronic address
    Mayo Clin Proc 88:683-9. 2013
  2. pmc Evaluation of alpha 1-antitrypsin and the levels of mRNA expression of matrix metalloproteinase 7, urokinase type plasminogen activator receptor and COX-2 for the diagnosis of colorectal cancer
    Luis Bujanda
    Department of Gastroenterology, Donostia Hospital Biodonostia Institute, University of Basque Country, UPV EHU, Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas, San Sebastian, Spain
    PLoS ONE 8:e51810. 2013
  3. pmc Colorectal cancer prognosis twenty years later
    Luis Bujanda
    Departament of Gastroenterology, CIBERehd, University of Country Basque, Donostia Hospital, Avda Sancho El Sabio, 17 2D, 20010 San Sebastian, Spain
    World J Gastroenterol 16:862-7. 2010
  4. doi request reprint [Clinicopathological characteristics and survival outcome of esophageal cancer. Results from a series of 200 patients]
    Luis Bujanda
    Servicio de Digestivo, Hospital Donostia, Universidad del Pais Vasco, CIBERehd, San Sebastian, Guipuzcoa, Espana
    Med Clin (Barc) 133:689-93. 2009
  5. pmc Low adherence to colonoscopy in the screening of first-degree relatives of patients with colorectal cancer
    Luis Bujanda
    Department of Gastroenterology, Donostia Hospital, San Sebastian, Spain
    Gut 56:1714-8. 2007
  6. doi request reprint [Clostridium-difficile-associated diarrhea]
    Luis Bujanda
    Servicio de Aparato Digestivo, Hospital Donostia, Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas CIBEREHD, San Sebastian, Espana
    Gastroenterol Hepatol 32:48-56. 2009
  7. pmc Resveratrol inhibits nonalcoholic fatty liver disease in rats
    Luis Bujanda
    Department of Gastroenterology, University of Country Basque, Donostia Hospital, Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas, San Sebastian, Spain
    BMC Gastroenterol 8:40. 2008
  8. doi request reprint Risk of advanced proximal neoplasms according to distal colorectal findings: comparison of sigmoidoscopy-based strategies
    Antoni Castells
    Department of Gastroenterology, Hospital Clinic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas CIBEREHD, IDIBAPS, University of Barcelona, Barcelona, Spain
    J Natl Cancer Inst 105:878-86. 2013
  9. pmc Biochemical determination of lipid content in hepatic steatosis by the Soxtec method
    Elizabeth Hijona
    Department of Gastroenterology, University of the Basque Country, Donostia Hospital, Center for Biomedical Research in Hepatic and Digestive Disease CIBERehd, 20014, San Sebastian, Spain
    World J Gastroenterol 16:1495-9. 2010
  10. doi request reprint Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype
    Anna Abuli
    Department of Gastroenterology, Hospital del Mar, Institut Municipal d Investigacio Medica, Pompeu Fabra University, Barcelona, Catalonia, Spain
    Gastroenterology 139:788-96, 796.e1-6. 2010

Detail Information

Publications40

  1. doi request reprint Effect of aspirin and antiplatelet drugs on the outcome of the fecal immunochemical test
    Luis Bujanda
    Department of Gastroenterology, Hospital Donostia, Instituto Biodonostia, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, Universidad del Pais Vasco, San Sebastian, Spain Electronic address
    Mayo Clin Proc 88:683-9. 2013
    ..To evaluate the effect of aspirin and nonaspirin antiplatelet agents (NAAAs) on the performance of the fecal immunochemical test (FIT)...
  2. pmc Evaluation of alpha 1-antitrypsin and the levels of mRNA expression of matrix metalloproteinase 7, urokinase type plasminogen activator receptor and COX-2 for the diagnosis of colorectal cancer
    Luis Bujanda
    Department of Gastroenterology, Donostia Hospital Biodonostia Institute, University of Basque Country, UPV EHU, Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas, San Sebastian, Spain
    PLoS ONE 8:e51810. 2013
    ..Colorectal cancer (CRC) is the second most common cause of death from cancer in both men and women in the majority of developed countries. Molecular tests of blood could potentially provide this ideal screening tool...
  3. pmc Colorectal cancer prognosis twenty years later
    Luis Bujanda
    Departament of Gastroenterology, CIBERehd, University of Country Basque, Donostia Hospital, Avda Sancho El Sabio, 17 2D, 20010 San Sebastian, Spain
    World J Gastroenterol 16:862-7. 2010
    ..To evaluate changes in colorectal cancer (CRC) survival over the last 20 years...
  4. doi request reprint [Clinicopathological characteristics and survival outcome of esophageal cancer. Results from a series of 200 patients]
    Luis Bujanda
    Servicio de Digestivo, Hospital Donostia, Universidad del Pais Vasco, CIBERehd, San Sebastian, Guipuzcoa, Espana
    Med Clin (Barc) 133:689-93. 2009
    ..The esophageal cancer (EC) is a slightly frequent but serious disease. Our aim is to describe the characteristics of the patients with EC in our Hospital...
  5. pmc Low adherence to colonoscopy in the screening of first-degree relatives of patients with colorectal cancer
    Luis Bujanda
    Department of Gastroenterology, Donostia Hospital, San Sebastian, Spain
    Gut 56:1714-8. 2007
    ..Colonoscopy is one of the methods of choice for screening relatives of patients with colorectal cancer...
  6. doi request reprint [Clostridium-difficile-associated diarrhea]
    Luis Bujanda
    Servicio de Aparato Digestivo, Hospital Donostia, Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas CIBEREHD, San Sebastian, Espana
    Gastroenterol Hepatol 32:48-56. 2009
    ..Relapse is frequent and must be distinguished from reinfection. Prevention and control in healthcare settings requires careful attention...
  7. pmc Resveratrol inhibits nonalcoholic fatty liver disease in rats
    Luis Bujanda
    Department of Gastroenterology, University of Country Basque, Donostia Hospital, Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas, San Sebastian, Spain
    BMC Gastroenterol 8:40. 2008
    ....
  8. doi request reprint Risk of advanced proximal neoplasms according to distal colorectal findings: comparison of sigmoidoscopy-based strategies
    Antoni Castells
    Department of Gastroenterology, Hospital Clinic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas CIBEREHD, IDIBAPS, University of Barcelona, Barcelona, Spain
    J Natl Cancer Inst 105:878-86. 2013
    ..This study was aimed at comparing the existing strategies of postsigmoidoscopy referral to colonoscopy in terms of accuracy and resources needed...
  9. pmc Biochemical determination of lipid content in hepatic steatosis by the Soxtec method
    Elizabeth Hijona
    Department of Gastroenterology, University of the Basque Country, Donostia Hospital, Center for Biomedical Research in Hepatic and Digestive Disease CIBERehd, 20014, San Sebastian, Spain
    World J Gastroenterol 16:1495-9. 2010
    ..To establish a quantitative method to measure the amount of lipids...
  10. doi request reprint Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype
    Anna Abuli
    Department of Gastroenterology, Hospital del Mar, Institut Municipal d Investigacio Medica, Pompeu Fabra University, Barcelona, Catalonia, Spain
    Gastroenterology 139:788-96, 796.e1-6. 2010
    ..Characterization of such a correlation would improve CRC management and prevention programs. We assessed the association between these genetic variants and CRC phenotype in patients and modeled pairwise combinations to detect epistasis...
  11. doi request reprint Effect of neoadjuvant chemotherapy in hepatic steatosis
    Raul Jimenez
    Department of Surgery, Donostia Hospital, San Sebastian, Spain
    Chemotherapy 58:89-94. 2012
    ..Conclusions: Almost half of the patients treated with NAC for liver neoplasia developed steatosis. Nevertheless, NAC does not seem to increase the risk of hepatic steatosis...
  12. doi request reprint Susceptibility genetic variants associated with early-onset colorectal cancer
    María Dolores Giráldez
    Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, IDIBAPS, University of Barcelona, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Carcinogenesis 33:613-9. 2012
    ..Association of CRC susceptibility variants with some patient's familiar and personal features could be relevant for screening and surveillance strategies in this high-risk group and it should be explored in further studies...
  13. doi request reprint Relationship of colonoscopy-detected serrated polyps with synchronous advanced neoplasia in average-risk individuals
    Cristina Alvarez
    Department of Gastroenterology, Hospital del Mar Cancer Research Program, IMIM Hospital del Mar Medical Research Institute, Universitat Autònoma de Barcelona Pompeu Fabra University, Barcelona, Catalonia, Spain
    Gastrointest Endosc 78:333-341.e1. 2013
    ..The presence of proximal serrated polyps and large (≥10 mm) serrated polyps (LSP) has been correlated with colorectal neoplasia...
  14. doi request reprint Colonoscopy versus fecal immunochemical testing in colorectal-cancer screening
    Enrique Quintero
    Department of Gastroenterology, Hospital Universitario de Canarias, Tenerife, Spain
    N Engl J Med 366:697-706. 2012
    ..Colonoscopy and fecal immunochemical testing (FIT) are accepted strategies for colorectal-cancer screening in the average-risk population...
  15. doi request reprint [Plasma levels of folate and vitamin B(12) in patients with chronic liver disease]
    Nerea Muro
    Servicio de Digestivo, Hospital Donostia, Universidad del Pais Vasco, CIBERehd, Instituto Carlos III, San Sebastian, Guipuzcoa, Espana
    Gastroenterol Hepatol 33:280-7. 2010
    ..Patients with liver disease frequently experience changes in their nutritional status...
  16. doi request reprint A comparison of Val81Met and other polymorphisms of alcohol metabolising genes in patients and controls in Northern Spain
    David Celorrio
    BIOMICs Research Group, CIBERehd, University of Basque Country UPV EHU, Spain
    Alcohol 46:427-31. 2012
    ..811 times (CI: 1.660-8.749) that the subjects carrying the genotype ADH1B*1/*2. Alleles Val and ADH1B*1 may therefore increase the risk of the onset and development of this illness...
  17. doi request reprint Time trends and impact of upper and lower gastrointestinal bleeding and perforation in clinical practice
    Angel Lanas
    Servicio de Aparato Digestivo, Hospital Clinico, Universidad de Zaragoza, Zaragoza, Spain
    Am J Gastroenterol 104:1633-41. 2009
    ....
  18. doi request reprint Circulating microRNAs as biomarkers of colorectal cancer: results from a genome-wide profiling and validation study
    María Dolores Giráldez
    Department of Gastroenterology, Hospital Clinic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Clin Gastroenterol Hepatol 11:681-8.e3. 2013
    ..We also investigated whether plasma samples from patients with premalignant neoplastic lesions, such as advanced adenomas (AAs), also had a different expression pattern of miRNAs...
  19. pmc Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models
    Elizabeth Hijona
    Department of Gastroenterology, Donostia Hospital, Instituto Biodonostia, University of the Basque Country EHU UPV, CIBERehd, San Sebastian, Spain
    Cancer Cell Int 12:5. 2012
    ..abstract:..
  20. doi request reprint Accurate fat fraction quantification by multiecho gradient-recalled-echo magnetic resonance at 1.5T in rats with nonalcoholic fatty liver disease
    Elizabeth Hijona
    Hospital Donostia, Department of Gastroenterology Centro de Investigaciones en Red de Enfermedades Hepáticas y Digestivas, University of Basque Country, Donostia, San Sebastian, Spain
    Eur J Radiol 81:1122-7. 2012
    ....
  21. pmc Effect of resveratrol on alcohol-induced mortality and liver lesions in mice
    Luis Bujanda
    Department of Gastroenterology, Donostia Hospital, San Sebastian, Spain
    BMC Gastroenterol 6:35. 2006
    ..Resveratrol is a polyphenol with important antiinflammatory and antioxidant properties. We investigated the effect of resveratrol on alcohol-induced mortality and liver lesions in mice...
  22. doi request reprint [Clinical and molecular features in a family with multiple endocrine neoplasia type-1 syndrome]
    Angel Cosme
    Servicio de Aparato Digestivo, Hospital Donostia, CIBERehd, Universidad del Pais Vasco, San Sebastian, Guipuzcoa, Spain
    Gastroenterol Hepatol 31:637-42. 2008
    ..This syndrome is due to mutations in the MEN1 gene, located on the q13 region of chromosome 11. Prognosis depends on tumoral growth and metastatic potential...
  23. doi request reprint Clinical patterns and outcomes of ischaemic colitis: results of the Working Group for the Study of Ischaemic Colitis in Spain (CIE study)
    Miguel A Montoro
    Department of Gastroenterology, Hospital San Jorge, Huesca, Spain
    Scand J Gastroenterol 46:236-46. 2011
    ..We performed such a study to evaluate the clinical presentation, outcome, and mortality as well as clinical variables associated with poor prognosis...
  24. doi request reprint Effect of proton pump inhibitors on the outcomes of peptic ulcer bleeding: comparison of event rates in routine clinical practice and a clinical trial
    Angel Lanas
    Servicio de Aparato Digestivo, Hospital Clinico, Universidad de Zaragoza, IIS Aragón, Zaragoza, Spain
    Scand J Gastroenterol 48:285-94. 2013
    ..v. esomeprazole...
  25. pmc Patterns of local recurrence in rectal cancer after a multidisciplinary approach
    Jose M Enríquez-Navascués
    Colorectal Cancer Multidisciplinary Unit, Donostia Hospital, University of the Basque Country, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, 20010 San Sebastian, Spain
    World J Gastroenterol 17:1674-84. 2011
    ..Overall survival after LR diagnosis is lower with radio or chemoradiotherapy plus optimal surgery approaches, compared to optimal surgery alone...
  26. ncbi request reprint Diagnosis of Whipple's disease using molecular biology techniques
    Angel Cosme
    Department of Digestive Diseases, Hospital Donostia, San Sebastian, Guipuzcoa, Spain
    Rev Esp Enferm Dig 103:213-7. 2011
    ..In both cases, the diagnosis was confirmed using molecular biology techniques to samples from the small intestine or from a retroperineal lymph node, respectively...
  27. pmc Inflammatory mediators of hepatic steatosis
    Elizabeth Hijona
    Gastroenterology Department, Donostia Hospital, CIBERehd, University of the Basque Country, 20010 San Sebastian, Spain
    Mediators Inflamm 2010:837419. 2010
    ..We review the role of cytokines as key regulators of insulin sensitivity and hepatic lipid overloading, liver injury and inflammation, and fibrosis with an emphasis on potential therapeutic implications...
  28. ncbi request reprint Effect of antisecretory drugs and nitrates on the risk of ulcer bleeding associated with nonsteroidal anti-inflammatory drugs, antiplatelet agents, and anticoagulants
    Angel Lanas
    Servicio de Aparato Digestivo, Hospital Clinico Zaragoza, CIBER HEPAD, Zaragoza, Spain
    Am J Gastroenterol 102:507-15. 2007
    ..Here, we report the effect of antisecretory drugs and nitrates on the risk of upper GI peptic ulcer bleeding (UGIB) associated with nonselective NSAIDs, aspirin, antiplatelet agents, and anticoagulants...
  29. ncbi request reprint Littoral-cell angioma of the spleen: a case report
    Angel Cosme
    Department of Gastroenterology, Hospital Donostia, Paseo Beguiristain, S N, 20014, San Sebastian Gipuzkoa, Spain
    World J Gastroenterol 13:6603-4. 2007
    ..Lining cells were positive for CD31/CD68 markers. Our case was associated with a serrated colonic adenoma. LCA is a benign vascular tumor of the spleen that needs to be included in the differential diagnosis of multiple splenic nodules...
  30. ncbi request reprint Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations
    Francisco Rodriguez-Moranta
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Am J Gastroenterol 101:1104-11. 2006
    ..For this purpose, the National Cancer Institute outlined a set of recommendations, the Bethesda guidelines, which have recently been revised...
  31. doi request reprint Molecular markers in pancreatic cancer diagnosis
    Marta Herreros-Villanueva
    Department of Gastroenterology, Hospital Donostia Instituto Biodonostia, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Universidad del Pais Vasco UPV EHU, San Sebastian, Spain
    Clin Chim Acta 418:22-9. 2013
    ..We keep the hope that a combination of some of these novel biomarkers can be a useful tool for early PDAC diagnosis before image techniques and/or patient's symptoms reveal disease in an incurable state...
  32. doi request reprint Alcohol-metabolizing enzyme gene polymorphisms in the Basque Country, Morocco, and Ecuador
    David Celorrio
    BIOMICs Research Group, Department of Z and Cell Biology, DNA Bank, University of Basque Country, Spain
    Alcohol Clin Exp Res 35:879-84. 2011
    ..This study sets out to examine the distribution of the frequencies of alleles that encode alcohol dehydrogenase with different metabolization rates, as higher rates make for greater susceptibility to alcoholism...
  33. doi request reprint Chemoprevention, chemotherapy, and chemoresistance in colorectal cancer
    Jose J G Marin
    Department of Physiology and Pharmacology, University of Salamanca, CIBERehd, Salamanca, Spain
    Drug Metab Rev 44:148-72. 2012
    ..This would minimize side effects and prevent the selection of aggressive, cross-resistant clones, as well as avoiding undesirable delays in the use of the most efficient therapeutic approaches to treat these patients...
  34. ncbi request reprint [Molecular and clinical characteristics of a family with Alagille syndrome]
    Angel Cosme
    Servicio de Aparato Digestivo, Hospital Donostia, San Sebastian, Guipuzcoa, Spain
    Med Clin (Barc) 130:17-9. 2008
    ..Mutations of Jagged 1 gene are observed in individuals with the full syndrome and/or relatives with little or no phenotypic features. Prognosis of patients depends on the hepatic and cardiovascular involvement...
  35. ncbi request reprint Cytomegalovirus hepatitis and myopericarditis
    Leire Zubiaurre
    Department of Digestive Disease, Hospital Donostia, Paseo Beguiristain S N, 20014 San Sebastián Gipúzcoa, Spain
    World J Gastroenterol 13:647-8. 2007
    ..The patient was diagnosed with myopericarditis and hepatitis caused by cytomegalovirus and started symptomatic treatment with salicylic acid. In few days the laboratory findings became normal and the patient was discharged...
  36. pmc Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer
    Victoria Gonzalo
    Department of Gastroenterology, Hospital Clinic, Centro de Investigación Biomédica en Red en el Area temática de Enfermedades Hepáticas y Digestivas, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
    PLoS ONE 5:e8777. 2010
    ....
  37. ncbi request reprint [Influence of lifestyle in patients with gastroesophageal reflux disease]
    Luis Bujanda
    Servicio de Digestivo, Hospital Donostia, San Sebastian, Guipuzcoa, Spain
    Med Clin (Barc) 128:550-4. 2007
    ..Nevertheless larger prospective controlled trials are warranted. Gum-chewing after eating, keep standing up and to go to bed 4 h after dinner improves the symptoms of the reflux and the gastro-esophageal reflux disease...
  38. doi request reprint Prevalence and factors related to hepatitis B and C in inflammatory bowel disease patients in Spain: a nationwide, multicenter study
    Carme Loras
    Department of Gastroenterology, Hospital Mutua de Terrassa, Fundació per la Recerca Mútua de Terrassa, Plaça Dr Robert no 5, Catalonia, Spain
    Am J Gastroenterol 104:57-63. 2009
    ..The objectives of this study are to assess the prevalence of HBV and HCV infection in IBD, in a nationwide study, and to evaluate associated risk factors...
  39. ncbi request reprint Sonographic findings of hepatic lesions in human fascioliasis
    Angel Cosme
    Service of Gastroenterology, Hospital Donostia, Paseo Dr Beguiristain, S N, San Sebastián 20014, Guipuzcoa, Spain
    J Clin Ultrasound 31:358-63. 2003
    ....
  40. ncbi request reprint 'Rescue' therapy with rifabutin after multiple Helicobacter pylori treatment failures
    Javier P Gisbert
    Department of Gastroenterology, La Princesa University Hospital, Madrid, Spain
    Helicobacter 8:90-4. 2003
    ..Our aim was to evaluate the efficacy and tolerability of a rifabutin-based regimen in patients with two consecutive H. pylori eradication failures...