E Bouza

Summary

Country: Spain

Publications

  1. ncbi request reprint Direct E-test (AB Biodisk) of respiratory samples improves antimicrobial use in ventilator-associated pneumonia
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Infect Dis 44:382-7. 2007
  2. ncbi request reprint A randomized and prospective study of 3 procedures for the diagnosis of catheter-related bloodstream infection without catheter withdrawal
    Emilio Bouza
    Clinical Microbiology and Infectious Diseases Service, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 44:820-6. 2007
  3. ncbi request reprint Predictive value of superficial cultures to anticipate tunneled hemodialysis catheter-related bloodstream infection
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain Department of Nephrology, Hospital General Universitario Gregorio Maranon, Madrid, Spain Universidad Complutense de Madrid, Madrid, Spain Red Española de Investigación en Patología Infecciosa REIPI, Sevilla, Spain Electronic address
    Diagn Microbiol Infect Dis 78:316-9. 2014
  4. doi request reprint Diagnosis of venous access port colonization requires cultures from multiple sites: should guidelines be amended?
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón, Department of Medicine, Universidad Complutense, Madrid, Spain Red Española de Investigación en Patología Infecciosa REIPI, RD06 0008 1025, Madrid, Spain Electronic address
    Diagn Microbiol Infect Dis 78:162-7. 2014
  5. ncbi request reprint Pre-emptive broad-spectrum treatment for ventilator-associated pneumonia in high-risk patients
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Intensive Care Med 39:1547-55. 2013
  6. doi request reprint Consequences of Clostridium difficile infection: understanding the healthcare burden
    E Bouza
    Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 18:5-12. 2012
  7. pmc Ventilator-associated pneumonia in patients undergoing major heart surgery: an incidence study in Europe
    Javier Hortal
    Anaesthesia Department, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Crit Care 13:R80. 2009
  8. pmc Evaluation of the new advanced 15-loci MIRU-VNTR genotyping tool in Mycobacterium tuberculosis molecular epidemiology studies
    Noelia Alonso-Rodriguez
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital Gregorio Maranon, Universidad Complutense, Madrid, Ciber de enfermedades respiratorias CIBERES, Spain
    BMC Microbiol 8:34. 2008
  9. pmc Rapid clonal analysis of recurrent tuberculosis by direct MIRU-VNTR typing on stored isolates
    Ana Martin
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, CIBER Enfermedades Respiratorias CIBERES, Universidad Complutense, Madrid, Spain
    BMC Microbiol 7:73. 2007
  10. pmc Optimized molecular resolution of cross-contamination alerts in clinical mycobacteriology laboratories
    Ana Martin
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital Gregorio Maranon, Universidad Complutense, Madrid, CIBER Enfermedades Respiratorias CIBERES, Spain
    BMC Microbiol 8:30. 2008

Collaborators

Detail Information

Publications160 found, 100 shown here

  1. ncbi request reprint Direct E-test (AB Biodisk) of respiratory samples improves antimicrobial use in ventilator-associated pneumonia
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Infect Dis 44:382-7. 2007
    ..Our study evaluates the clinical and financial impact of performing rapid antimicrobial susceptibility tests directly on samples obtained from the lower respiratory tract...
  2. ncbi request reprint A randomized and prospective study of 3 procedures for the diagnosis of catheter-related bloodstream infection without catheter withdrawal
    Emilio Bouza
    Clinical Microbiology and Infectious Diseases Service, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 44:820-6. 2007
    ..The objective of this study was to compare the yield of 3 microbiological procedures to assess CR-BSI without catheter withdrawal...
  3. ncbi request reprint Predictive value of superficial cultures to anticipate tunneled hemodialysis catheter-related bloodstream infection
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain Department of Nephrology, Hospital General Universitario Gregorio Maranon, Madrid, Spain Universidad Complutense de Madrid, Madrid, Spain Red Española de Investigación en Patología Infecciosa REIPI, Sevilla, Spain Electronic address
    Diagn Microbiol Infect Dis 78:316-9. 2014
    ..The sensitivity and negative predictive value were high, and we succeeded in identifying a subpopulation at low risk of infection. ..
  4. doi request reprint Diagnosis of venous access port colonization requires cultures from multiple sites: should guidelines be amended?
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón, Department of Medicine, Universidad Complutense, Madrid, Spain Red Española de Investigación en Patología Infecciosa REIPI, RD06 0008 1025, Madrid, Spain Electronic address
    Diagn Microbiol Infect Dis 78:162-7. 2014
    ..The best validity values were those obtained when cultures of catheter tip (roll-plate), PSF, and port ISB were combined. Cultures from several areas on the VAP are necessary to ensure suitable assessment of colonization and VAP-RBSI. ..
  5. ncbi request reprint Pre-emptive broad-spectrum treatment for ventilator-associated pneumonia in high-risk patients
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Intensive Care Med 39:1547-55. 2013
    ..The objective of this study was to evaluate the efficacy in preventing lower respiratory infections of antibiotics active against multidrug-resistant pathogens in this very high-risk population...
  6. doi request reprint Consequences of Clostridium difficile infection: understanding the healthcare burden
    E Bouza
    Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 18:5-12. 2012
    ..Moreover, estimates suggest that costs associated with recurrent CDI can exceed those of primary CDI. Measures to more effectively prevent CDI and reduce CDI recurrence rates may help to reduce this burden...
  7. pmc Ventilator-associated pneumonia in patients undergoing major heart surgery: an incidence study in Europe
    Javier Hortal
    Anaesthesia Department, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Crit Care 13:R80. 2009
    ..Our aim was to determine the incidence, aetiology, risk factors and outcome of ventilator-associated pneumonia (VAP) in patients who have undergone MHS in Europe...
  8. pmc Evaluation of the new advanced 15-loci MIRU-VNTR genotyping tool in Mycobacterium tuberculosis molecular epidemiology studies
    Noelia Alonso-Rodriguez
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital Gregorio Maranon, Universidad Complutense, Madrid, Ciber de enfermedades respiratorias CIBERES, Spain
    BMC Microbiol 8:34. 2008
    ..Recently, a new version of MIRU-VNTR targeting 15 loci (MIRU-15) has been proposed to improve the MIRU-12 format...
  9. pmc Rapid clonal analysis of recurrent tuberculosis by direct MIRU-VNTR typing on stored isolates
    Ana Martin
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, CIBER Enfermedades Respiratorias CIBERES, Universidad Complutense, Madrid, Spain
    BMC Microbiol 7:73. 2007
    ....
  10. pmc Optimized molecular resolution of cross-contamination alerts in clinical mycobacteriology laboratories
    Ana Martin
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital Gregorio Maranon, Universidad Complutense, Madrid, CIBER Enfermedades Respiratorias CIBERES, Spain
    BMC Microbiol 8:30. 2008
    ..Our purpose in this study is to evaluate a novel PCR-based method, MIRU-VNTR as an alternative to assure a rapid and optimized analysis of cross-contamination alerts...
  11. ncbi request reprint A needleless closed system device (CLAVE) protects from intravascular catheter tip and hub colonization: a prospective randomized study
    E Bouza
    Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    J Hosp Infect 54:279-87. 2003
    ..Multivariate analysis showed that CLAVE use was an independent protective factor for tip colonization. CLAVE offered significant protection from catheter-tip and hub colonization...
  12. ncbi request reprint Introduction. Staphylococcal infections--whatever next?
    E Bouza
    Servicio de Microbiología Clínica y E Infecciosas, Hospital Gregorio Maranon, University of Madrid, Madrid, Spain
    Clin Microbiol Infect 12:1-2. 2006
  13. ncbi request reprint Ventilator-associated pneumonia after heart surgery: a prospective analysis and the value of surveillance
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Disease, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Crit Care Med 31:1964-70. 2003
    ..To study the predictive role of systematic surveillance cultures...
  14. ncbi request reprint [Pseudomonas aeruginosa: a multicenter study in 136 hospitals in Spain]
    E Bouza
    Servicio de Microbiologia, Hospital General Universitario Gregorio Maranon, Madrid
    Rev Esp Quimioter 16:41-52. 2003
    ..In Spain, P. aeruginosa is much more than a cause of severe nosocomial infections in immunocompromised patients...
  15. doi request reprint Advances in the prevention and management of ventilator-associated pneumonia
    Emilio Bouza
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Curr Opin Infect Dis 22:345-51. 2009
    ..We review the current state of the prevention, diagnosis, and treatment of VAP, paying special attention to data reported over the past year...
  16. doi request reprint Selection of the vascular catheter: can it minimise the risk of infection?
    E Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Int J Antimicrob Agents 36:S22-5. 2010
    ..The available evidence suggests that chlorhexidine-silver sulfadiazine, minocycline-rifampicin CVCs and antifungal-coated catheters are useful in decreasing the incidence of CRBSI when other measures are not effective...
  17. ncbi request reprint [The contribution of the microbiology laboratory to the diagnosis of ventilator-associated pneumonia]
    Emilio Bouza
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Espana
    Enferm Infecc Microbiol Clin 23:2-9. 2005
    ..The impact of using this procedure in clinical practice is currently under research...
  18. ncbi request reprint Demolition of a hospital building by controlled explosion: the impact on filamentous fungal load in internal and external air
    E Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    J Hosp Infect 52:234-42. 2002
    ..Demolition work was associated with a significant increase in the fungal colony counts of hospital external and non-protected internal air. Effective protective measures may be taken to avoid the emergence of clinical infections...
  19. doi request reprint New therapeutic choices for infections caused by methicillin-resistant Staphylococcus aureus
    E Bouza
    Servicio de Microbiología Clínica y E Infecciosas, Hospital General Universitario Gregorio Maranon, Universidad Complutenste, Madrid, and Ciber de Enfermedades Respiratories CIBERES, Spain
    Clin Microbiol Infect 15:44-52. 2009
    ..g. vancomycin, and also newer anti-MRSA antimicrobials, e.g. second-generation glycolipopeptides, tigecycline, and beta-lactams...
  20. doi request reprint Epidemiology of candidemia in intensive care units
    Emilio Bouza
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Red de Investigací on en Patología Infecciosa, Spain
    Int J Antimicrob Agents 32:S87-91. 2008
    ..Candidemia in ICUs is associated with a considerable increase in hospital costs and length of hospital stay...
  21. ncbi request reprint Semiquantitative culture of open surgical wounds for diagnosis of surgical site infection
    E Bouza
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, 46 Dr Esquerdo, 28007, Madrid, Spain
    Eur J Clin Microbiol Infect Dis 23:119-22. 2004
    ..5%-99%) for the semiquantitative method. This result indicates that our easy-to-perform semiquantitative culture technique for open surgical wounds correlates better with the diagnosis of SSI than the traditional qualitative method...
  22. ncbi request reprint Invasive infections caused by Blastoschizomyces capitatus and Scedosporium spp
    E Bouza
    Servicio de Microbiología Clínica y E Infecciosas, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Microbiol Infect 10:76-85. 2004
    ..Prognosis is poor unless patients recover from neutropenia. Voriconazole has good in-vitro activity and is currently the drug of choice for these infections...
  23. ncbi request reprint Microbiologic workload and clinical significance of Streptococcus pneumoniae isolated during one week in Spain
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Gregorio Maranon, Dr Esquerdo 46, 28007 Madrid, Spain
    Microb Drug Resist 13:52-61. 2007
    ..A nationwide point-prevalence study is an efficient tool for surveying pneumococcal infection in a large population...
  24. pmc Is the volume of blood cultured still a significant factor in the diagnosis of bloodstream infections?
    Emilio Bouza
    Division of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Clin Microbiol 45:2765-9. 2007
    ..08). We conclude that the higher yield of blood cultures inoculated with lower volumes of blood reflects the conditions of the population cultured. Washington's dictum holds true today in the era of automated blood culture machines...
  25. ncbi request reprint Fever of unknown origin in solid organ transplant recipients
    Emilio Bouza
    Division of Clinical Microbiology and Infections, Universidad Complutense de Madrid, Hospital General Universitario Gregorio Maranon, Dr Esquerdo 46, 28007 Madrid, Spain
    Infect Dis Clin North Am 21:1033-54, ix-x. 2007
    ..This article examines an approach that considers different syndromes, followed by an etiologically oriented differential diagnosis...
  26. ncbi request reprint The challenge of anticipating catheter tip colonization in major heart surgery patients in the intensive care unit: are surface cultures useful?
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Crit Care Med 33:1953-60. 2005
    ..We evaluated whether skin insertion site and catheter hub surveillance cultures ("surface cultures") could predict catheter colonization and help establish the origin of bloodstream infections...
  27. ncbi request reprint Bloodstream infections: a trial of the impact of different methods of reporting positive blood culture results
    Emilio Bouza
    Division of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Infect Dis 39:1161-9. 2004
    ..The impact of how positive blood culture results are reported on the evolution bloodstream infections (BSIs) has not been assessed...
  28. ncbi request reprint A European perspective on intravascular catheter-related infections: report on the microbiology workload, aetiology and antimicrobial susceptibility (ESGNI-005 Study)
    E Bouza
    Clinical Microbiology and Infectious Diseases, Hospital General Gregorio Maranon, 28007 Madrid, Spain
    Clin Microbiol Infect 10:838-42. 2004
    ..4% of coagulase-negative staphylococcus isolates. Of 37 Gram-negative isolates, 35% were resistant to cefotaxime, 31% to ceftazidime, and 27% to ciprofloxacin. Imipenem and cefepime had the lowest reported rates of resistance (11%)...
  29. ncbi request reprint Nosocomial bloodstream infections caused by Streptococcus pneumoniae
    E Bouza
    Division of Clinical Microbiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 11:919-24. 2005
    ..7; 95% CI, 4.9--820.7; p<0.001). Adequate empirical therapy was an independent protective factor (OR, 0.05; 95% CI, 0.04--0.58; p<0.005), but the use of more than one antimicrobial agent was not...
  30. doi request reprint Continuous aspiration of subglottic secretions in the prevention of ventilator-associated pneumonia in the postoperative period of major heart surgery
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Chest 134:938-46. 2008
    ..We compared conventional and continuous aspiration of subglottic secretions (CASS) procedures in ventilated patients after major heart surgery (MHS)...
  31. ncbi request reprint Endotipsitis: an emerging prosthetic-related infection in patients with portal hypertension
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Diagn Microbiol Infect Dis 49:77-82. 2004
    ..Prolonged courses of antimicrobial agents can be curative, but liver transplantation is also an option to consider...
  32. ncbi request reprint Klebsiella and enterobacter: antibiotic resistance and treatment implications
    Emilio Bouza
    Servicio de Microbiología Clínica and Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
    Semin Respir Infect 17:215-30. 2002
    ..Because of the high risk for developing resistance during treatment, all severe infections should be carefully watched during therapy...
  33. doi request reprint Oritavancin: a novel lipoglycopeptide active against Gram-positive pathogens including multiresistant strains
    Emilio Bouza
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
    Int J Antimicrob Agents 36:401-7. 2010
    ..Further results indicating its activity against bacteria growing in biofilms as well as stationary-phase bacteria open the way for its use to treat prosthetic device infections, which is to be investigated in upcoming trials...
  34. doi request reprint Managing intravascular catheter-related infections in heart transplant patients: how far can we apply IDSA guidelines for immunocompromised patients?
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Curr Opin Infect Dis 24:302-8. 2011
    ..It also updates newly available information of possible interest to the care of heart transplant patients...
  35. ncbi request reprint A prospective search for ocular lesions in hospitalized patients with significant bacteremia
    E Bouza
    Serviciode Microbiología Clínica y E Infecciosas, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Clin Infect Dis 30:306-12. 2000
    ....
  36. ncbi request reprint Laboratory-acquired brucellosis: a Spanish national survey
    E Bouza
    Servicio de Microbiología Clínica Unidad de Enfermedades Infecciosas VIH, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Hosp Infect 61:80-83. 2005
    ..No differences in resolution were observed according to the antimicrobial regimen. Microbiological laboratory workers are still at risk of developing LAB. Improvements in safety seem to be the best means of..
  37. ncbi request reprint Infections in systemic lupus erythematosus and rheumatoid arthritis
    E Bouza
    Clinical Microbiology and Infectious Disease Service, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    Infect Dis Clin North Am 15:335-61, vii. 2001
    ..It is estimated that at least 50% of them will suffer a severe infectious episode during the course of the disease. Improvements in the control of the disease are discussed in this article...
  38. ncbi request reprint Monotherapy versus combination therapy for bacterial infections
    E Bouza
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    Med Clin North Am 84:1357-89, v. 2000
    ..They offer suggestions for treatment based on a host of considerations, including the synergy and antagonism of specific drugs, type of infection, potential toxicities, and cost...
  39. ncbi request reprint Antibiotic resistance and therapeutic options in lower respiratory tract infections
    E Bouza
    Enfermedades Infecciosas HIV, Hospital G U Gregorio Marañón, Madrid, Spain
    Int J Antimicrob Agents 11:S3-6; discussion S31-2. 1999
    ..Infections caused by resistant organisms can usually be successfully treated using traditional therapeutic approaches...
  40. ncbi request reprint A European perspective on nosocomial urinary tract infections I. Report on the microbiology workload, etiology and antimicrobial susceptibility (ESGNI-003 study). European Study Group on Nosocomial Infections
    E Bouza
    Servicio de Microbiología Clínica y Enfermedades Infecciosas_VIH, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 7:523-31. 2001
    ..To obtain information on the microbiology workload, etiology and antimicrobial susceptibility of urinary tract infection (UTI) pathogens isolated in European hospitals...
  41. ncbi request reprint A European perspective on nosocomial urinary tract infections II. Report on incidence, clinical characteristics and outcome (ESGNI-004 study). European Study Group on Nosocomial Infection
    E Bouza
    Servicio de Microbiologia, Clínica y Enfermedades Infecciosas VIH, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 7:532-42. 2001
    ..To estimate the incidence of nosocomially acquired urinary tract infections (NAUTI) in Europe and provide information on the clinical characteristics, underlying conditions, etiology, management and outcome of patients...
  42. ncbi request reprint Linezolid: pharmacokinetic characteristics and clinical studies
    E Bouza
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 7:75-82. 2001
    ....
  43. ncbi request reprint Catheter-related infections: diagnosis and intravascular treatment
    E Bouza
    Servicio de Microbiología Clínica y E Infecciosas, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Microbiol Infect 8:265-74. 2002
    ..New diagnostic and therapeutic techniques may avoid the unnecessary withdrawal of thousands of efficient, difficult to replace and expensive intravascular lines...
  44. doi request reprint [Relationships with microbiology: the view from other specialties]
    Emilio Bouza Santiago
    Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Espana
    Enferm Infecc Microbiol Clin 28:39-44. 2010
    ..In all these reflections, the questions of where we come from and where we are going are explicit or implicit...
  45. ncbi request reprint Catheter-related infections: diagnosis and intravascular treatment
    E Bouza
    Servicio de Microbiología Clínica y E Infecciosas, Hospital General Universitario Gregorio Marafñón, Universidad Complutense, Madrid, Spain
    J Chemother 13:224-33. 2001
    ..New diagnostic and therapeutic techniques may avoid the unnecessary withdrawal of thousands of efficient, difficult to replace and expensive intravascular lines...
  46. pmc Pseudomonas aeruginosa: a survey of resistance in 136 hospitals in Spain. The Spanish Pseudomonas aeruginosa Study Group
    E Bouza
    Servicio de Microbiología y Enfermedades Infecciosas VIH, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Antimicrob Agents Chemother 43:981-2. 1999
    ..The most frequent serotypes were O:1 (25.1%), O:4 (21.6%), and O:11 (11.3%)...
  47. pmc Metronidazole resistance in Clostridium difficile is heterogeneous
    T Pelaez
    Microbiology and Infectious Disease Service, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Clin Microbiol 46:3028-32. 2008
    ..We recommend routine performance of the disk diffusion method (5-microg metronidazole disk) with primary fresh C. difficile isolates in order to ensure that metronidazole-heteroresistant populations do not go undetected...
  48. ncbi request reprint IgG monitoring to identify the risk for development of infection in heart transplant recipients
    E Sarmiento
    Clinical Immunology Unit, Cardiology Department, University Hospital Gregorio Maranon, Madrid, Spain
    Transpl Infect Dis 8:49-53. 2006
    ..21; CI 1.04-89.48; P=0.022) were associated with an increase in the risk for developing infections. Early monitoring of immunoglobulin levels might help to identify the risk for developing infection in heart transplantation...
  49. doi request reprint Re-analysis of epidemiologically linked tuberculosis cases not supported by IS6110-RFLP-based genotyping
    A Martin
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital Gregorio Maranon, 28007 Madrid, Spain
    Clin Microbiol Infect 15:763-9. 2009
    ....
  50. pmc Use of universal 16S rRNA gene PCR as a diagnostic tool for venous access port-related bloodstream infections
    M Guembe
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón, Universidad Complutense, Madrid, Spain
    J Clin Microbiol 51:799-804. 2013
    ..Therefore, we propose a new application of 16S rRNA PCR as a useful tool for the diagnosis of VAP-RBSI in patients receiving antibiotic therapy...
  51. doi request reprint Outbreak of invasive aspergillosis after major heart surgery caused by spores in the air of the intensive care unit
    T Pelaez
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 54:e24-31. 2012
    ..Few studies have established a correlation between high levels of Aspergillus fumigatus conidia and the appearance of new cases of IA or have demonstrated matching genotypes between clinical isolates and those from the environment...
  52. pmc Value of superficial cultures for prediction of catheter-related bloodstream infection in long-term catheters: a prospective study
    M Guembe
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón, Universidad Complutense, Madrid, Spain
    J Clin Microbiol 51:3025-30. 2013
    ..Superficial cultures (from skin and hubs) proved to be a useful conservative diagnostic tool for ruling out C-RBSI among patients with long-term tunneled catheters and totally implantable venous access ports. ..
  53. ncbi request reprint The potential impact of substitutive therapy with intravenous immunoglobulin on the outcome of heart transplant recipients with infections
    J Carbone
    Clinical Immunology Unit, University Hospital Gregorio Maranon, Madrid, Spain
    Transplant Proc 39:2385-8. 2007
    ..06, CI = 0.0060 to 0.63, P = .01]. The use of nonspecific IVIG in OHT with hypogammaglobulinemia and infections might reduce the risk of death. Randomized studies in a larger cohort of patients are necessary to confirm these results...
  54. doi request reprint Differential findings regarding molecular epidemiology of tuberculosis between two consecutive periods in the context of steady increase of immigration
    J Inigo
    Consejeria de Sanidad, Comunidad de Madrid, Madrid, Spain
    Clin Microbiol Infect 19:292-7. 2013
    ..In our region, the decrease in the incidence of TB can be explained predominantly as a result of a decline in recent transmission...
  55. doi request reprint BK virus infection in human immunodeficiency virus-infected patients
    J Ledesma
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007, Madrid, Spain
    Eur J Clin Microbiol Infect Dis 31:1531-5. 2012
    ..We provide an update on the prevalence of BKV in HIV-infected patients treated with HAART. BKV viruria was more common in HIV-infected patients; however, no role for BKV has been demonstrated in this population...
  56. ncbi request reprint Postoperative infections after major heart surgery and prevention of ventilator-associated pneumonia: a one-day European prevalence study (ESGNI-008)
    E Bouza
    Servicio de Microbiología Clínica y Enfermedades Infecciosas VIH, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Hosp Infect 64:224-30. 2006
    ....
  57. ncbi request reprint Clinical-epidemiological characteristics and outcome of patients with catheter-related bloodstream infections in Europe (ESGNI-006 Study)
    P Munoz
    Clinical Microbiology and Infectious Diseases, Hospital General Gregorio Maranon, 28007 Madrid, Spain
    Clin Microbiol Infect 10:843-5. 2004
    ..In 36% of cases, catheters were implanted by physicians other than anaesthetists or surgeons, and 50% were inserted by junior staff...
  58. ncbi request reprint Decreased levels of serum immunoglobulins as a risk factor for infection after heart transplantation
    E Sarmiento
    Clinical Immunology Unit, University Hospital Gregorio Maranon, Madrid, Spain
    Transplant Proc 37:4046-9. 2005
    ..We aimed to assess humoral immunity markers that provide prognostic value for the development of infections in heart transplant recipients...
  59. doi request reprint Candida tropicalis fungaemia: incidence, risk factors and mortality in a general hospital
    P Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Microbiol Infect 17:1538-45. 2011
    ..06; 95% CI 0.01-0.4; p 0.002) were protective factors. C. tropicalis is the fourth most common cause of fungaemia in our hospital. It is associated with underlying malignancy, the abdomen as the portal of entry, and poor outcome...
  60. doi request reprint The undiagnosed cases of Clostridium difficile infection in a whole nation: where is the problem?
    L Alcala
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 18:E204-13. 2012
    ..C. difficile toxins should be routinely sought in unformed stools of any origin sent for microbiological diagnosis. The ribotype 027 clone has not yet disseminated in Spain...
  61. ncbi request reprint Evaluation of alternatives to RFLP for the analysis of clustered cases of tuberculosis
    D Garcia de Viedma
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital Gregorio Maranon, Madrid, Spain
    Int J Tuberc Lung Dis 10:454-9. 2006
    ..Mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) analysis is a recently developed method which could be suitable as a 'real-time' genotyping tool for Mycobacterium tuberculosis...
  62. pmc Heterogeneous antimicrobial resistance patterns in polyclonal populations of coagulase-negative staphylococci isolated from catheters
    D Garcia de Viedma
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    J Clin Microbiol 38:1359-63. 2000
    ..The frequent isolation of polyclonal CoNS populations from catheters, with heterogeneous antimicrobial susceptibility patterns, has relevant epidemiologic and therapeutic implications in the context of catheter-related infections...
  63. ncbi request reprint "Second-look" cytotoxicity: an evaluation of culture plus cytotoxin assay of Clostridium difficile isolates in the laboratory diagnosis of CDAD
    E Bouza
    Department of Clinical Microbiology and Infectious Diseases, , C/Dr. Esquerdo, 46, 28007 Madrid, Spain
    J Hosp Infect 48:233-7. 2001
    ..difficile and "second-look" cell culture assay enhances the potential for diagnosis of CDAD and enables us to be more efficient with our patient care resources...
  64. doi request reprint Differences in the robustness of clusters involving the Mycobacterium tuberculosis strains most frequently isolated from immigrant cases in Madrid
    N Alonso Rodríguez
    Hospital Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 16:1544-54. 2010
    ....
  65. ncbi request reprint Bloodstream infections in patients with kidney disease: risk factors for poor outcome and mortality
    L Rojas
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Hosp Infect 85:196-205. 2013
    ..Information regarding bloodstream infections (BSIs) in patients with kidney diseases is scarce and mainly derived from selected groups of patients...
  66. doi request reprint Evolution and aetiological shift of catheter-related bloodstream infection in a whole institution: the microbiology department may act as a watchtower
    M Rodriguez-Creixems
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón, Madrid, Spain
    Clin Microbiol Infect 19:845-51. 2013
    ..We demonstrated a significant reduction in the incidence of CR-BSI in recent years in the population admitted to adult ICUs but not in the remaining areas of the hospital. A shift in the aetiological spectrum of CR-BSI may be occurring...
  67. doi request reprint BK polyomavirus genotyping at inter- and intra-patient level in Spain
    J Ledesma
    Influenza and Respiratory Viruses Laboratory, National Center for Microbiology, ISCIII, Majadahonda, Madrid, Spain
    J Med Virol 85:1402-8. 2013
    ..The potential involvement in the viral cycle of the different BKV variants found should be analyzed...
  68. pmc Reassessment of Clostridium difficile susceptibility to metronidazole and vancomycin
    T Pelaez
    Microbiology and Infectious Diseases Service, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Antimicrob Agents Chemother 46:1647-50. 2002
    ..Molecular typing methods proved the absence of clonality among the isolates with decreased susceptibilities to the antimicrobials tested...
  69. ncbi request reprint Clinical manifestations, treatment and control of infections caused by Clostridium difficile
    E Bouza
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, C Dr Esquerdo, 46, 28007 Madrid, Spain
    Clin Microbiol Infect 11:57-64. 2005
    ..The administration of probiotics such as Saccharomyces boulardii, Lactobacillus sp. or brewer's yeast for prophylaxis of CDAD remains controversial...
  70. doi request reprint Laboratory diagnosis of Clostridium difficile infection in Spain: a population-based survey
    L Alcala
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Hosp Infect 79:13-7. 2011
    ....
  71. pmc Antifungal susceptibility of 596 Aspergillus fumigatus strains isolated from outdoor air, hospital air, and clinical samples: analysis by site of isolation
    J Guinea
    Servicio de Microbiologia, Hospital Universitario Gregorio Maranon, Calle Doctor Esquerdo, 46, 28007 Madrid, Spain
    Antimicrob Agents Chemother 49:3495-7. 2005
    ..We did not find differences among the susceptibilities by site of isolation...
  72. ncbi request reprint Evolution of the antimicrobial resistance of Pseudomonas aeruginosa in Spain: second national study (2003)
    I Sanchez-Romero
    Servicio de Microbiologia, Hospital Puerta de Hierro, Madrid, Spain
    Rev Esp Quimioter 20:222-9. 2007
    ..aeruginosa to antimicrobial agents has changed. Isolates have become significantly more resistant to fluoroquinolones and carbapenems. However, resistance to beta-lactams and aminoglycosides remains stable...
  73. doi request reprint Differential time to positivity (DTTP) for the diagnosis of catheter-related bloodstream infection: do we need to obtain one or more peripheral vein blood cultures?
    M Guembe
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Eur J Clin Microbiol Infect Dis 31:1367-72. 2012
    ..8% (p>0.999) of episodes would have been documented. When performing the DTTP technique to confirm CLABSI, a single paired PV blood culture was not associated with a significant number of missed CLABSI episodes...
  74. ncbi request reprint Nasal carriage of S. aureus increases the risk of surgical site infection after major heart surgery
    P Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Hosp Infect 68:25-31. 2008
    ..8-19.2; P=0.04) and diabetes mellitus (RR: 5.9; 95% CI: 1.8-19.2; P=0.003). Nasal carriage of S. aureus significantly increases the rate of nosocomial SSI after MHS and decolonisation strategies should be implemented in this population...
  75. ncbi request reprint Extra-intestinal infections caused by Clostridium difficile
    J M Garcia-Lechuz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 7:453-7. 2001
    ..Death could not be directly attributed to C. difficile in any of the cases. The isolation of C. difficile outside the intestinal tract is very uncommon. Its clinical significance should be interpreted with caution...
  76. ncbi request reprint Environmental surveillance and other control measures in the prevention of nosocomial fungal infections
    P Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 7:38-45. 2001
    ..We review the currently available Center for Disease Control recommendations and report our own experiences in the field. The indications and problems of fungal environmental and patient surveillance are also discussed...
  77. pmc Workload due to Aspergillus fumigatus and significance of the organism in the microbiology laboratory of a general hospital
    E Bouza
    Clinical Microbiology and Infectious Diseases Department, Servicio de Microbiologia, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Clin Microbiol 43:2075-9. 2005
    ..A simple score based on five easily available parameters may be of help to microbiologists and clinicians to predict the risk of IA...
  78. ncbi request reprint In vitro activity of new quinolones against Clostridium difficile
    R Alonso
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, 28007 Madrid, Spain
    J Antimicrob Chemother 47:195-7. 2001
    ..None of the antimicrobials studied would be a reliable therapeutic option against C. difficile. Whether some of the new fluoroquinolones can induce C. difficile-associated diarrhoea remains to be answered...
  79. pmc In vitro activities of six fluoroquinolones against 250 clinical isolates of Mycobacterium tuberculosis susceptible or resistant to first-line antituberculosis drugs
    M J Ruiz-Serrano
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Antimicrob Agents Chemother 44:2567-8. 2000
    ..Trovafloxacin and gemifloxacin showed lower in vitro activity, with MIC(90)s of 64 and 8 microg/ml, respectively...
  80. ncbi request reprint Lung nodular lesions in heart transplant recipients
    P Munoz
    Clinical Microbiology Infectious Diseases Division, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Heart Lung Transplant 19:660-7. 2000
    ..Ten percent of HT patients developed lung nodules that were mainly caused by Aspergillus, Nocardia, and CMV. The time of appearance and some clinical manifestations may suggest the etiology and may help in the empirical treatment...
  81. ncbi request reprint Rapid detection of toxigenic Clostridium difficile from stool samples by a nested PCR of toxin B gene
    R Alonso
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Hosp Infect 41:145-9. 1999
    ..3% and 100% respectively. The procedure described is easy to perform, does not require special equipment and has produced excellent results. It deserves serious consideration for routine clinical microbiology laboratory use...
  82. pmc Prospective universal application of mycobacterial interspersed repetitive-unit-variable-number tandem-repeat genotyping to characterize Mycobacterium tuberculosis isolates for fast identification of clustered and orphan cases
    Noelia Alonso-Rodriguez
    Servicio de Microbiologia, Hospital Gregorio Maranon, Madrid, Spain
    J Clin Microbiol 47:2026-32. 2009
    ..The correlation between MIRU-15 and IS6110 RFLP findings was reasonable, although some uncertainties as to the assignation of clusters by MIRU-15 analysis were identified...
  83. doi request reprint Transmission permeability of tuberculosis involving immigrants, revealed by a multicentre analysis of clusters
    N Alonso Rodriguez
    Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 15:435-42. 2009
    ..This study revealed marked transmission permeability among nationalities and between the immigrant and the autochthonous populations...
  84. pmc Characterization of Mycobacterium tuberculosis Beijing isolates from the Mediterranean area
    M Alonso
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital Gregorio Maranon, Madrid, Spain
    BMC Microbiol 10:151. 2010
    ..In this study, we analyze Beijing isolates in the Mediterranean area, where this lineage is not prevalent and is mainly associated with immigrant cases...
  85. pmc Antimicrobial susceptibilities of 1,684 Streptococcus pneumoniae and 2,039 Streptococcus pyogenes isolates and their ecological relationships: results of a 1-year (1998-1999) multicenter surveillance study in Spain
    E Perez-Trallero
    Microbiology Department, Hospital Donostia, San Sebastian, Madrid, Spain
    Antimicrob Agents Chemother 45:3334-40. 2001
    ..5% of S. pyogenes isolates. Ciprofloxacin resistance (MIC, >or=4 microg/ml) was significantly (P < 0.05) associated with macrolide resistance in both S. pyogenes and S. pneumoniae and with penicillin nonsusceptibility in S. pneumoniae...
  86. pmc In vitro activity of ramoplanin against Clostridium difficile, including strains with reduced susceptibility to vancomycin or with resistance to metronidazole
    T Pelaez
    Deparment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, C Dr Esquerdo 46, 28007, Madrid, Spain
    Antimicrob Agents Chemother 49:1157-9. 2005
    ..25 microg/ml; geometric mean MIC, 0.22 microg/ml). All isolates, independently of their levels of susceptibility to vancomycin or metronidazole, were considered susceptible to ramoplanin (MICs, < or =0.5 microg/ml)...
  87. pmc Methicillin-resistant Staphylococcus aureus in Spain: molecular epidemiology and utility of different typing methods
    Ana Vindel
    Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
    J Clin Microbiol 47:1620-7. 2009
    ....
  88. ncbi request reprint Increased incidence of pneumococcal bloodstream infections
    Marta Rodriguez-Creixems
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Pediatr Infect Dis J 22:661-3. 2003
    ..Incidence in the group <24 months of age increased from 7.4 to 78.6 episodes per 100,000 per year (P < 0.001). Overall 75% of the serogroups are included in the new heptavalent vaccine...
  89. doi request reprint Community-acquired methicillin-resistant Staphylococcus aureus in Madrid, Spain: transcontinental importation and polyclonal emergence of Panton-Valentine leukocidin-positive isolates
    Emilia Cercenado
    Servicio de Microbiologia, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Diagn Microbiol Infect Dis 61:143-9. 2008
    ..Nine patients were from South America. Our results indicate the transcontinental importation and recent emergence in Spain of PVL-positive CA-MRSA strains belonging to 3 distinct lineages, including 1 predominant (ST8-SCCmec IVc)...
  90. pmc Rapid direct detection of multiple rifampin and isoniazid resistance mutations in Mycobacterium tuberculosis in respiratory samples by real-time PCR
    Mercedes Marin
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, C Dr Esquerdo 46, 28007 Madrid, Spain
    Antimicrob Agents Chemother 48:4293-300. 2004
    ..tuberculosis bacteria. This real-time PCR design is an adequate method for the specific and rapid detection of RIF and INH resistance in smear-positive clinical respiratory samples...
  91. doi request reprint Recurrent Escherichia coli bloodstream infections: epidemiology and risk factors
    Marta Sanz-García
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Ciber de enfermedades respiratorias CIBERES, Madrid, Spain
    Medicine (Baltimore) 88:77-82. 2009
    ..Recurrence of E. coli BSI is not an uncommon phenomenon and includes relapses (47%) and reinfections (53%). Recurrence should suggest not only the presence of urinary or biliary obstruction, but also the presence of immunosuppression...
  92. ncbi request reprint An instant procedure to demonstrate catheter-tip colonization may help clinicians
    Emilio Bouza
    Clinical Microbiology and Infectious Diseases Service, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Diagn Microbiol Infect Dis 56:255-60. 2006
    ..3%/100%; PPV, 86.7%/100.0%; NPV, 100%/93.9%; and full concordance, 97.0%/94.7%. Catheter-tip staining before culture is an easy-to-perform, cheap, and effective procedure to anticipate catheter colonization and rule out CRBSIs...
  93. pmc In vitro activity of linezolid against Clostridium difficile
    T Pelaez
    Microbiology and Infectious Diseases Service, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Antimicrob Agents Chemother 46:1617-8. 2002
    ..The MIC at which 50% of the isolates were inhibited (MIC50) and MIC90 were 0.5 and 2 microg/ml, respectively (range, 0.03 to 4 microg/ml). MICs were always <or= 4 microg/ml, and thus, all isolates were considered susceptible...
  94. doi request reprint A proposal for applying molecular markers as an aid to identifying potential cases of imported tuberculosis in immigrants
    Maria Alonso
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital Gregorio Maranon, CIBER Enfermedades Respiratorias CIBERES, C Dr Esquerdo 46, 28007 Madrid, Spain
    Tuberculosis (Edinb) 88:641-7. 2008
    ..The analysis of certain bacterial molecular markers could help to discriminate between potentially imported TB cases and those more probably acquired in the host country...
  95. ncbi request reprint In vitro activity of linezolid against multiply resistant Gram-positive clinical isolates
    E Cercenado
    Servicio de Microbiologia, Hospital General Universitario Gregorio Maranon, Dr Esquerdo 46, 28007 Madrid, Spain
    J Antimicrob Chemother 47:77-81. 2001
    ..The MIC(90) of linezolid for all isolates was 2 mg/L...
  96. pmc Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain
    Laura Calatayud
    Servicio de Microbiologia, Hospital Universitario de Bellvitge, Feixa Llarga s n 08907, L Hospitalet de Llobregat, Barcelona, Spain
    Antimicrob Agents Chemother 51:3240-6. 2007
    ....
  97. ncbi request reprint Molecular, epidemiological and infectivity characterisation of a Mycobacterium tuberculosis strain prevalent in Madrid
    A Martin
    Clinical Microbiology and Infectious Diseases Service, Gregorio Maranon Hospital, Madrid, Spain
    Clin Microbiol Infect 13:1210-3. 2007
    ..Patients infected with strain 5 were more frequently positive for human immunodeficiency virus and autochthonous, and had been in prison more frequently, but strain 5 did not show increased infectivity in an in-vitro model of infection...
  98. doi request reprint Advanced survey of tuberculosis transmission in a complex socioepidemiologic scenario with a high proportion of cases in immigrants
    Miguel Martínez-Lirola
    Servicio de Microbiologia, Hospital Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 47:8-14. 2008
    ..Standard contact tracing is not suitable for the survey of transmission in this complex scenario...
  99. ncbi request reprint Contaminated feeding bottles: the source of an outbreak of Pseudomonas aeruginosa infections in a neonatal intensive care unit
    Carlos Sánchez-Carrillo
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Am J Infect Control 37:150-4. 2009
    ..The incidence of P aeruginosa infection/colonization in our neonatal intensive care unit increased from 1.9 per 1000 patient-days in August 2004 to 8.8 per 1000 patient-days in September 2004...
  100. pmc Dual qualitative-quantitative nested PCR for detection of JC virus in cerebrospinal fluid: high potential for evaluation and monitoring of progressive multifocal leukoencephalopathy in AIDS patients receiving highly active antiretroviral therapy
    D Garcia de Viedma
    Servicio de Microbiología y Enfermedades Infecciosas HIV, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    J Clin Microbiol 37:724-8. 1999
    ..The dual quantitative-qualitative application offered by this nested PCR may provide an answer to the new requirements for evaluating and finely monitoring PML in AIDS patients receiving HAART...
  101. ncbi request reprint Evaluation of bone marrow and blood cultures for the recovery of mycobacteria in the diagnosis of disseminated mycobacterial infections
    E Pacios
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Clin Microbiol Infect 10:734-7. 2004
    ....