Xavier Bosch

Summary

Country: Spain

Publications

  1. pmc Primary care referrals of patients with potentially serious diseases to the emergency department or a quick diagnosis unit: a cross-sectional retrospective study
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Villarroel 170, Barcelona 08036, Spain
    BMC Fam Pract 15:75. 2014
  2. pmc Challenging Medical Ghostwriting in US Courts
    Xavier Bosch
    Department of Internal Medicine at the Hospital Clínic and the Institut d Investigacions Biomèdiques August Pí i Sunyer, University of Barcelona, Barcelona, Spain
    PLoS Med 9:e1001163. 2012
  3. doi request reprint Financial, nonfinancial and editors' conflicts of interest in high-impact biomedical journals
    Xavier Bosch
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Eur J Clin Invest 43:660-7. 2013
  4. pmc Misconduct policies in high-impact biomedical journals
    Xavier Bosch
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Barcelona, Spain
    PLoS ONE 7:e51928. 2012
  5. doi request reprint Quick diagnosis units: avoiding referrals from primary care to the ED and hospitalizations
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Spain
    Am J Emerg Med 31:114-23. 2013
  6. doi request reprint Comparison of quick diagnosis units and conventional hospitalization for the diagnosis of cancer in Spain: a descriptive cohort study
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Oncology 83:283-91. 2012
  7. doi request reprint Aspiration pneumonia in old patients with dementia. Prognostic factors of mortality
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Eur J Intern Med 23:720-6. 2012
  8. doi request reprint [Systemic lupus erythematosus in the elderly]
    Xavier Bosch
    Unidad de Geriatria, Servicio de Medicina Interna, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universidad de Barcelona, Barcelona, Spain
    Rev Esp Geriatr Gerontol 47:71-5. 2012
  9. doi request reprint The DWEYS peptide in systemic lupus erythematosus
    Xavier Bosch
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Trends Mol Med 18:215-23. 2012
  10. ncbi request reprint Quick diagnosis units or conventional hospitalisation for the diagnostic evaluation of severe anaemia: a paradigm shift in public health systems?
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Eur J Intern Med 23:159-64. 2012

Detail Information

Publications121 found, 100 shown here

  1. pmc Primary care referrals of patients with potentially serious diseases to the emergency department or a quick diagnosis unit: a cross-sectional retrospective study
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Villarroel 170, Barcelona 08036, Spain
    BMC Fam Pract 15:75. 2014
    ..As a secondary objective, we determined the proportion of QDU patients who might have been evaluated in a less rapid, non-QDU setting...
  2. pmc Challenging Medical Ghostwriting in US Courts
    Xavier Bosch
    Department of Internal Medicine at the Hospital Clínic and the Institut d Investigacions Biomèdiques August Pí i Sunyer, University of Barcelona, Barcelona, Spain
    PLoS Med 9:e1001163. 2012
    b>Xavier Bosch and colleagues expand upon a recent analysis by Simon Stern and Trudo Lemmens in PLoS Medicine and outline areas in which authors participating in medical ghostwriting could be held legally liable.
  3. doi request reprint Financial, nonfinancial and editors' conflicts of interest in high-impact biomedical journals
    Xavier Bosch
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Eur J Clin Invest 43:660-7. 2013
    ..To assess financial, nonfinancial and editors' conflicts of interest (COI) disclosure policies among the most influential biomedical journals publishing original research...
  4. pmc Misconduct policies in high-impact biomedical journals
    Xavier Bosch
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Barcelona, Spain
    PLoS ONE 7:e51928. 2012
    ..This study assessed the prevalence and content policies of the most influential biomedical journals on misconduct and procedures for handling and responding to allegations of misconduct...
  5. doi request reprint Quick diagnosis units: avoiding referrals from primary care to the ED and hospitalizations
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Spain
    Am J Emerg Med 31:114-23. 2013
    ..The aim of the present study was to determine whether quick diagnosis units (QDUs) can safely and efficiently avoid emergency department (ED) visits and hospitalizations...
  6. doi request reprint Comparison of quick diagnosis units and conventional hospitalization for the diagnosis of cancer in Spain: a descriptive cohort study
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Oncology 83:283-91. 2012
    ..We compared the value and cost of a QDU and of conventional hospitalization in assessing patients with cancer...
  7. doi request reprint Aspiration pneumonia in old patients with dementia. Prognostic factors of mortality
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Eur J Intern Med 23:720-6. 2012
    ..Prognostic factors of mortality in elderly patients with dementia with aspiration pneumonia (AP) are scarcely known. We determined the mortality rate and prognostic factors in old patients with dementia hospitalized due to AP...
  8. doi request reprint [Systemic lupus erythematosus in the elderly]
    Xavier Bosch
    Unidad de Geriatria, Servicio de Medicina Interna, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universidad de Barcelona, Barcelona, Spain
    Rev Esp Geriatr Gerontol 47:71-5. 2012
    ..In addition to the need for adopting a multidisciplinary approach, it is fundamental to obtain information about the functional, cognitive and social status of these patients in order to make appropriate healthcare decisions...
  9. doi request reprint The DWEYS peptide in systemic lupus erythematosus
    Xavier Bosch
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Trends Mol Med 18:215-23. 2012
    ..In this review, anti-dsDNA antibodies as a pathogenic factor in SLE and recent efforts for the creation of highly specific, nontoxic therapeutics against an extremely pathogenic subset of such antibodies is discussed...
  10. ncbi request reprint Quick diagnosis units or conventional hospitalisation for the diagnostic evaluation of severe anaemia: a paradigm shift in public health systems?
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Eur J Intern Med 23:159-64. 2012
    ..Anaemia with haemoglobin levels below 8 g/l has traditionally been a criterion used to hospitalise patients in our centre for diagnosis...
  11. doi request reprint Monoclonal antibody therapy-associated neurological disorders
    Xavier Bosch
    Department of Internal Medicine, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Nat Rev Neurol 7:165-72. 2011
    ....
  12. doi request reprint Dendrimers to treat rheumatoid arthritis
    Xavier Bosch
    Department of Internal Medicine, Hospital Clínic, University of Barcelona, Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    ACS Nano 5:6779-85. 2011
    ..This Perspective highlights this important development and the challenges that lie ahead...
  13. doi request reprint Vasculitis syndromes: LAMP-2 illuminates pathogenesis of ANCA glomerulonephritis
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Nat Rev Nephrol 5:247-9. 2009
    ..The discovery that antibodies to a bacterial antigen can cross-react with a mammalian protein to cause pauci-immune necrotizing and crescentic glomerulonephritis opens up new possibilities for the diagnosis and treatment of this condition...
  14. pmc Outpatient Quick Diagnosis Units for the evaluation of suspected severe diseases: an observational, descriptive study
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Clinics (Sao Paulo) 66:737-41. 2011
    ..Hospitals in countries with public health systems have recently adopted organizational changes to improve efficiency and resource allocation, and reducing inappropriate hospitalizations has been established as an important goal...
  15. ncbi request reprint Immunotherapy for antineutrophil cytoplasmic antibody-associated vasculitis: challenging the therapeutic status quo?
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Trends Immunol 29:280-9. 2008
    ..Therefore, an unmet need for safer and more effective therapies has prompted interest in biological agents. Continuous advances in the knowledge of AAV pathogenesis are paving the way to new biologicals that are now awaiting testing...
  16. ncbi request reprint Treatment of antineutrophil cytoplasmic antibody associated vasculitis: a systematic review
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Barcelona, Spain
    JAMA 298:655-69. 2007
    ..Long-term treatment and disease-related morbidity are major threats. The last decade has seen a collaborative international effort to determine effective treatment...
  17. ncbi request reprint Quick diagnosis units: a potentially useful alternative to conventional hospitalisation
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Med J Aust 191:496-8. 2009
    ..They reduce costs without lowering the quality of diagnostic practice or patient care, and free acute-care beds for patients in need of treatment...
  18. pmc An open challenge. Open access and the challenges for scientific publishing
    Xavier Bosch
    Department of Internal Medicine at the University of Barcelona s Hospital Clínic in Barcelona, Spain
    EMBO Rep 9:404-8. 2008
  19. doi request reprint Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies: the OVERCOME trial (preventiOn of left Ventricular dysfunction with Enalapril and caRvedilol in patients submitted t
    Xavier Bosch
    Cardiology Department, Thorax Institute, Hospital Clinic, Barcelona, Spain
    J Am Coll Cardiol 61:2355-62. 2013
    ..This study sought to evaluate the efficacy of enalapril and carvedilol to prevent chemotherapy-induced left ventricular systolic dysfunction (LVSD) in patients with hematological malignancies...
  20. ncbi request reprint Classification and characterisation of peripheral neuropathies in 102 patients with primary Sjögren's syndrome
    Pilar Brito-Zeron
    Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Spain
    Clin Exp Rheumatol 31:103-10. 2013
    ....
  21. doi request reprint Relation of plasma brain natriuretic peptide levels on admission for ST-elevation myocardial infarction to left ventricular end-diastolic volume six months later measured by both echocardiography and cardiac magnetic resonance
    Ana García-Alvarez
    Thorax Clinic Institute, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Am J Cardiol 104:878-82. 2009
    ..The early determination of plasma BNP upon admission for STEMI could be helpful in identifying patients at higher risk for LV dilatation, in whom aggressive management is warranted...
  22. ncbi request reprint Anti-Ro52 antibody testing influences the classification and clinical characterisation of primary Sjögren's syndrome
    Soledad Retamozo
    Department Autoimmune Diseases, Hospital Clinic, Barcelona, Spain
    Clin Exp Rheumatol 30:686-92. 2012
    ..To evaluate how determination of antibodies against the Ro52 antigen influences the classification and clinical characterisation of patients with suspected primary Sjögren's syndrome (SS)...
  23. doi request reprint Monoclonal gammopathy related to Sjögren syndrome: a key marker of disease prognosis and outcomes
    Pilar Brito-Zeron
    Sjögren Syndrome Research Group AGAUR, Laboratory of Autoimmune Diseases Josep Font, Institut d Investigacions Biomediques August Pi i Sunyer, Department of Autoimmune Diseases, ICMiD, Hospital Clinic, Barcelona, Spain
    J Autoimmun 39:43-8. 2012
    ....
  24. ncbi request reprint New insights in the management of cardiogenic shock complicating myocardial infarction: role of urgent heart transplantation
    Dabit Arzamendi
    Cardiology Unit, Cardio Thorax Institute Hospital Clinic de Barcelona, Barcelona, Spain
    J Heart Lung Transplant 27:984-9. 2008
    ..The primary end-point of the study was mortality at the 1-year follow-up...
  25. ncbi request reprint Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes
    Xavier Bosch
    Department of Cardiology, Hospital Clinic, University of Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Villarroel 170, Barcelona, Spain, 08036
    Cochrane Database Syst Rev 11:CD002130. 2013
    ..Glycoprotein IIb/IIIa blockers strongly inhibit platelet aggregation and may prevent mortality and myocardial infarction. This is an update of a Cochrane review first published in 2001, and previously updated in 2007 and 2010...
  26. doi request reprint Hepatitis B virus (HBV) reactivation in patients receiving tumor necrosis factor (TNF)-targeted therapy: analysis of 257 cases
    Roberto Perez-Alvarez
    Laboratory of Autoimmune Diseases Josep Font, IDIBAPS, Department of Autoimmune Diseases, ICMiD, and Liver Unit, CIBERehd, Hospital Clinic, Barcelona, Spain
    Medicine (Baltimore) 90:359-71. 2011
    ..The increasing number of reported cases of HBV reactivation following TNF-targeted therapies and the associated morbidity and mortality demand specific preventive strategies...
  27. ncbi request reprint B-cell depleting agents for ANCA vasculitides: a new therapeutic approach
    José A Gómez-Puerta
    Department of Rheumatology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Autoimmun Rev 11:646-52. 2012
    ..However, issues regarding the use of maintenance therapy after rituximab, the concurrent use of cyclophosphamide and the toxicity of rituximab remain unanswered and should be clarified in ongoing and future randomized controlled trials...
  28. doi request reprint Should alternatives to conventional hospitalisation be promoted in an era of financial constraint?
    Juan M Pericas
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Eur J Clin Invest 43:602-15. 2013
    ..This review aims to present the available evidence on alternatives to conventional hospitalisation for medical disorders; options for surgery, psychiatry and palliative care are largely excluded...
  29. pmc Role of circulating angiotensin converting enzyme 2 in left ventricular remodeling following myocardial infarction: a prospective controlled study
    José T Ortiz-Pérez
    Thorax Institute, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    PLoS ONE 8:e61695. 2013
    ..3 to 15.2, p = 0.027). In conclusion, serum sACE2 activity rises in relation to infarct size, left ventricular systolic dysfunction and is associated with the occurrence of left ventricular remodeling...
  30. ncbi request reprint Prevalence, clinical characteristics and risk of myocardial infarction in patients with cocaine-related chest pain
    Xavier Bosch
    Servicio de Cardiologia, Institut del Tòrax, Hospital Clínic e Institut d Investigacions Biomèdiques August Pi i Sunyer, Departamento de Medicina, Universidad de Barcelona, Barcelona, Espana
    Rev Esp Cardiol 63:1028-34. 2010
    ....
  31. ncbi request reprint The cryoglobulinaemias
    Manuel Ramos-Casals
    Josep Font Laboratory of Autoimmune Diseases, Institut Clinic de Medicina i Dermatologia, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Lancet 379:348-60. 2012
    ..Studies suggest that both combined or sequential antiviral therapies and targeted biological treatments might be more effective than monotherapy...
  32. doi request reprint Ischaemic postconditioning revisited: lack of effects on infarct size following primary percutaneous coronary intervention
    Xavier Freixa
    Interventional Cardiology Section, Cardiology Department, Thorax Institute, Hospital Clinic, University of Barcelona, Villarroel 170, Barcelona 08036, Catalonia, Spain
    Eur Heart J 33:103-12. 2012
    ..Previous studies have shown that p-cond during primary percutaneous coronary intervention (PCI) confers protection against ischaemia-reperfusion injury and thus might reduce myocardial infarct size...
  33. doi request reprint Treatment of polymyalgia rheumatica: a systematic review
    José Hernández-Rodríguez
    Department of Internal Medicine, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Arch Intern Med 169:1839-50. 2009
    ..Our objective was to systematically examine the peer-reviewed literature on PMR therapy, particularly the optimal glucocorticoid type, starting doses, and subsequent reduction regimens as well as glucocorticoid-sparing medications...
  34. doi request reprint Prevalence, clinical characteristics and risk of myocardial infarction in patients with cocaine-related chest pain
    Xavier Bosch
    Servicio de Cardiologia, Institut del Tòrax, Hospital Clínic e Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, Departamento de Medicina, Universidad de Barcelona, Barcelona, Spain
    Rev Esp Cardiol (Engl Ed) 63:1028-34. 2010
    ....
  35. ncbi request reprint Cryoglobulinemic disease
    Soledad Retamozo
    Laboratory of Autoimmune Diseases Josep Font, Department of Autoimmune Diseases, CELLEX, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    Oncology (Williston Park) 27:1098-1105, 1110-6. 2013
    ..hyperviscosity), and the severity of internal organ involvement...
  36. ncbi request reprint WAERS: an application for Web-assisted estimation of relative survival
    Ramon Clèries
    Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, L Hospitalet de Llobregat Spain, Barcelona, Spain
    Med Inform Internet Med 32:169-75. 2007
    ..This application can be also useful for cohort mortality studies and for registries of several diseases...
  37. ncbi request reprint Hospital deaths of people aged 90 and over: end-of-life palliative care management
    Francesc Formiga
    Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L Hospitalet de Llobregat, Barcelona, Spain
    Gerontology 54:148-52. 2008
    ..In developed countries, hospital deaths at very advanced age are increasingly common. Few studies have addressed end-of-life care in very elderly patients with non-cancer chronic diseases...
  38. doi request reprint Interstitial lung disease induced or exacerbated by TNF-targeted therapies: analysis of 122 cases
    Roberto Perez-Alvarez
    Department of Internal Medicine, Hospital do Meixoeiro, Vigo, Spain
    Semin Arthritis Rheum 41:256-64. 2011
    ..To analyze the clinical characteristics, outcomes, and patterns of association with the different biologic agents used in all reported cases of adult patients developing interstitial lung disease (ILD) after biologic therapy...
  39. doi request reprint Pulmonary disorders induced by monoclonal antibodies in patients with rheumatologic autoimmune diseases
    Manuel Ramos-Casals
    Department of Autoimmune Diseases, Laboratory of Autoimmune Diseases Josep Font, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Spain
    Am J Med 124:386-94. 2011
    ..Large, prospective, postmarketing studies including nonbiological agents as controls may help elucidate the real risk of pulmonary disease in patients with rheumatologic autoimmune diseases receiving monoclonal antibodies...
  40. ncbi request reprint Antineutrophil cytoplasmic antibody-associated vasculitides and respiratory disease
    José A Gómez-Puerta
    Departments of Rheumatology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Chest 136:1101-11. 2009
    ..Thus, biological agents are emerging as potential therapies in refractory cases. Notably, rituximab and infliximab have been trialed with apparent initial clinical success...
  41. ncbi request reprint Diagnosing unexplained fever: can quick diagnosis units replace inpatient hospitalization?
    Pilar Brito-Zeron
    Department of Autoimmune Diseases, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Eur J Clin Invest 44:707-18. 2014
    ..No study has prospectively evaluated the usefulness of QDU for the diagnosis of unexplained fever...
  42. ncbi request reprint Adult haemophagocytic syndrome
    Manuel Ramos-Casals
    Josep Font Laboratory of Autoimmune Diseases CELLEX, Department of Autoimmune Diseases, Institut Clinic de Medicina i Dermatologia, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Lancet 383:1503-16. 2014
    ..Insufficient knowledge of these syndromes could contribute to poor prognosis. Early diagnosis is essential to initiate appropriate treatment and improve the quality of life and survival of patients with this challenging disorder...
  43. ncbi request reprint Antineutrophil cytoplasmic antibodies
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Lancet 368:404-18. 2006
    ..Accurate understanding of the key pathogenic points of ANCA-associated vasculitis can undoubtedly provide a more rational therapeutic approach...
  44. doi request reprint Topical and systemic medications for the treatment of primary Sjögren's syndrome
    Manuel Ramos-Casals
    Sjögren s Syndrome Research Group AGAUR, Laboratory of Autoimmune Diseases Josep Font, Department of Autoimmune Diseases, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Nat Rev Rheumatol 8:399-411. 2012
    ..On the basis of this evidence, we provide guidance on the use of these agents in different clinical scenarios...
  45. doi request reprint [Prevalence of atrial fibrillation and related factors in hospitalized old patients: ESFINGE study]
    Alfonso Lopez Soto
    Servicio de Medicina Interna, Instituto Clínico de Medicina y Dermatología, Hospital Clinic de Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Barcelona, Espana
    Med Clin (Barc) 138:231-7. 2012
    ..The main objective of this study was to assess the prevalence of AF in hospitalized old patients as well as its characteristics and related clinical and therapeutic factors...
  46. pmc Anti-neutrophil cytoplasmic antibody pathogenesis in small-vessel vasculitis: an update
    José A Gómez-Puerta
    Department of Internal Medicine, Hospital Clinic, Barcelona, Spain
    Am J Pathol 175:1790-8. 2009
    ..Understanding the key pathogenic mechanisms of AAV may provide a safer, more rational therapeutic approach than the traditional (ie, corticosteroids and immunosuppressants) treatment strategy...
  47. doi request reprint Non-myeloablative hematopoietic stem cell transplantation in the treatment of severe idiopathic CD4+ lymphocytopenia
    Carlos Cervera
    Services of Infectious Diseases, Hospital Clinic of Barcelona, University of Barcelona, IDIBAPS, Barcelona, Spain
    Eur J Haematol 87:87-91. 2011
    ..Non-myeloablative allogeneic hematopoietic stem cell transplantation should be considered a treatment option for patients with severe forms of idiopathic CD4+ lymphocytopenia...
  48. ncbi request reprint Technetium 99m-labeled tetrofosmin and iodine 123-labeled metaiodobenzylguanidine scintigraphy in the assessment of transmyocardial laser revascularization
    Africa Muxi
    Servei de Medicina Nuclear Centre de Diagnóstic per la Imatge, Hospital Clinic, Universitat de Barcelona, Spain
    J Thorac Cardiovasc Surg 125:1493-8. 2003
    ..The aim of this study was to assess whether transmyocardial laser revascularization produces changes in innervation, perfusion scintigraphy, or both that could explain the benefit to patients...
  49. doi request reprint Usefulness of serum tumor markers, including progastrin-releasing peptide, in patients with lung cancer: correlation with histology
    Rafael Molina
    Laboratory of Biochemistry Oncobiology Unit, University of Barcelona, ES 08036 Barcelona, Spain
    Tumour Biol 30:121-9. 2009
    ..Tumor markers have been extensively studied in lung cancer, reporting some relationship to the histology, but their clinical utility is not clear...
  50. doi request reprint Angiographic and magnetic resonance imaging evaluation of in-hospital delay in primary percutaneous intervention delivery on myocardial salvage
    José T Ortiz-Pérez
    Feinberg Cardiovascular Research Institute and Division of Cardiology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA
    Am J Cardiol 106:924-30. 2010
    ..01). In conclusion, myocardial salvage progressively decreases up to 5 hours after symptom onset. However, the benefit of the recommended door-to-balloon time appears to be confined to patients presenting within 1 hour of symptom onset...
  51. ncbi request reprint [Reduction in acute myocardial infarction mortality over a five-year period]
    Magda Heras
    Servicio de Cardiologia, Hospital Clinic, Barcelona, Espana
    Rev Esp Cardiol 59:200-8. 2006
    ..To assess recent changes in the management of patients with acute myocardial infarction (AMI) and their impact on mortality using data from the PRIAMHO I and II registries (1995 and 2000)...
  52. ncbi request reprint Additional value of B-type natriuretic peptide on discrimination of patients at risk for mortality after a non-ST-segment elevation acute coronary syndrome
    Ana García-Alvarez
    University of Barcelona, Barcelona, Spain
    Eur Heart J Acute Cardiovasc Care 3:132-40. 2014
    ..We aimed to evaluate whether BNP levels provide additional improvement on discrimination and reclassification of patients at risk of mortality during admission and follow up after a NSTE-ACS...
  53. doi request reprint Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes
    Xavier Bosch
    Department of Cardiology, Hospital Clinic, University of Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Villarroel 170, Barcelona, Spain, 08036
    Cochrane Database Syst Rev 10:CD002130. 2013
    ..Glycoprotein IIb/IIIa blockers strongly inhibit platelet aggregation and may prevent mortality and myocardial infarction. This is an update of a Cochrane review first published in 2001, and previously updated in 2007 and 2010...
  54. doi request reprint Early risk stratification of patients with cardiogenic shock complicating acute myocardial infarction who undergo percutaneous coronary intervention
    Ana García-Alvarez
    Cardiology Department, Thorax Institute, Hospital Clinic, Institut d Investigaciones Biomèdiques August Pi i Sunyer, University of Barcelona, Spain
    Am J Cardiol 103:1073-7. 2009
    ..A simple risk score rapidly available in the catheterization laboratory can efficiently estimate prognosis...
  55. ncbi request reprint A practical approach with outcome for the prognostic assessment of non-ST-segment elevation chest pain and normal troponin
    Juan Sanchis
    Servei de Cardiologia, Hospital Clinic Universitari, Universitat de Valencia, Barcelona, Spain
    Am J Cardiol 99:797-801. 2007
    ....
  56. doi request reprint Shoshin beriberi mimicking a high-risk non-ST-segment elevation acute coronary syndrome with cardiogenic shock: when the arteries are not guilty
    Pablo Loma-Osorio
    Unidad Coronaria, Servicio de Cardiologia, Hospital Clinic, Barcelona, Spain
    J Emerg Med 41:e73-7. 2011
    ..Cardiac acute beriberi (Shoshin syndrome) is a rare disease that may lead to a fatal outcome if not treated specifically...
  57. pmc B-cell-depleting therapy in systemic lupus erythematosus
    Manuel Ramos-Casals
    Laboratory of Autoimmune Diseases Josep Font, IDIBAPS, Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Spain
    Am J Med 125:327-36. 2012
    ....
  58. doi request reprint Therapeutic targeting of B cells for rheumatic autoimmune diseases
    Pablo Engel
    Immunology Unit, Department of Cell Biology, Immunology and Neuroscience, Faculty of Medicine, University of Barcelona, Barcelona, Spain
    Pharmacol Rev 63:127-56. 2011
    ....
  59. ncbi request reprint Role of hepatitis C virus infection in malignant lymphoma in Spain
    Silvia de Sanjose
    Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Barcelona, Spain
    Int J Cancer 111:81-5. 2004
    ..HCV infection is associated with an increased risk of a broad spectrum of lymphoid neoplasms among non severely immunocompromised subjects in Spain...
  60. ncbi request reprint Usefulness of anti-p155 autoantibody for diagnosing cancer-associated dermatomyositis: a systematic review and meta-analysis
    Ernesto Trallero-Araguás
    Vall d Hebron General Hospital, Barcelona, Spain
    Arthritis Rheum 64:523-32. 2012
    ..We performed a systematic review and meta-analysis to ascertain the accuracy of anti-p155 testing for the diagnosis of cancer-associated myositis...
  61. ncbi request reprint Causes of ineligibility in randomized controlled trials and long-term mortality in patients with non-ST-segment elevation acute coronary syndromes
    Xavier Bosch
    Department of Cardiology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Spain
    Int J Cardiol 124:86-91. 2008
    ....
  62. ncbi request reprint [Performance assessment of an emergency department chest pain unit]
    Ernest Bragulat
    Servicio de Urgencias, Area de Urgencias, Hospital Clinic, Barcelona, Spain
    Rev Esp Cardiol 60:276-84. 2007
    ....
  63. doi request reprint Prevention of chemotherapy-induced left ventricular dysfunction with enalapril and carvedilol: rationale and design of the OVERCOME trial
    Xavier Bosch
    Cardiology Department, Thorax Institute, Hospital Clinic, Barcelona, Spain
    J Card Fail 17:643-8. 2011
    ....
  64. doi request reprint Utility of serum tumor markers as an aid in the differential diagnosis of patients with clinical suspicion of cancer and in patients with cancer of unknown primary site
    Rafael Molina
    Laboratory of Clinical Biochemistry Unit for Cancer Research, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Villarroel 170, Barcelona, 08036, Spain
    Tumour Biol 33:463-74. 2012
    ....
  65. doi request reprint Therapy: Spleen tyrosine kinase inhibitors--novel therapies for RA?
    José A Gómez-Puerta
    Arthritis Unit, Department of Rheumatology, Hospital Clinic, Villarroel 170, Barcelona, Spain
    Nat Rev Rheumatol 7:134-6. 2011
    ..Where might these agents fit in the current armamentarium against this disease?..
  66. pmc Basophils, IgE, and autoantibody-mediated kidney disease
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Bimoèdiques August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Spain
    J Immunol 186:6083-90. 2011
    ..In addition to envisaging exciting therapeutic prospects, these novel findings open the way for the study of basophils in other autoimmune and renal diseases...
  67. ncbi request reprint Left ventricular ejection fraction to predict early mortality in patients with non-ST-segment elevation acute coronary syndromes
    Xavier Bosch
    Institut de Malalties Cardiovasculars, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Am Heart J 150:215-20. 2005
    ..This study examines whether the routine determination of left ventricular ejection fraction (EF) adds significant prognostic information to currently recommended stratifiers...
  68. pmc Kikuchi-Fujimoto disease
    Xavier Bosch
    Department of Internal Medicine, Hospital Clinic, University of Barcelona, Spain
    Orphanet J Rare Dis 1:18. 2006
    ..Spontaneous recovery occurs in 1 to 4 months. Patients with Kikuchi-Fujimoto disease should be followed-up for several years to survey the possibility of the development of systemic lupus erythematosus...
  69. ncbi request reprint Treatment of primary Sjögren syndrome: a systematic review
    Manuel Ramos-Casals
    Sjögren Syndrome Research Group AGAUR, Josep Font Laboratory of Autoimmune Diseases, IDIBAPS, Department of Autoimmune Diseases, Hospital Clinic, C Villarroel, 170, 08036 Barcelona, Spain
    JAMA 304:452-60. 2010
    ..A variety of topical and systemic drugs are available to treat primary Sjögren syndrome, although no evidence-based therapeutic guidelines are currently available...
  70. ncbi request reprint Prognostic usefulness of white blood cell count on admission and one-year outcome in patients with non-ST-segment elevation acute chest pain
    Juan Sanchis
    Servei de Cardiologia, Hospital Clinic Universitari, Universitat de Valencia, Valencia, Spain
    Am J Cardiol 98:885-9. 2006
    ..However, in the absence of myocardial necrosis, leukocyte count lacks prognostic value...
  71. ncbi request reprint [Management of myocardial infarction in Spain in the year 2000. The PRIAMHO II study]
    Fernando Aros
    Area de Cardiología y Críticos Hospital Txagorritxu Vitoria España
    Rev Esp Cardiol 56:1165-73. 2003
    ..Hospital registries are useful tools to measure the degree of implementation of new treatments and clinical practice guidelines...
  72. ncbi request reprint [Long-term prognosis of women with non-ST-segment elevation acute coronary syndromes. a case-control study]
    Xavier Bosch
    Institut de Malalties Cardiovasculars Hospital Clínic Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS Departament de Medicina Universitat de Barcelona España
    Rev Esp Cardiol 55:1235-42. 2002
    ..However, information about the prognosis of women with non-ST-segment-elevation acute coronary syndromes (NSTEACS) is scarce. The aim of this study was to determine if the long-term prognosis of men and women with NSTEACS differs...
  73. ncbi request reprint [Reperfusion treatment in an acute myocardial infarction in patients older than 75 years. Do we need a randomized controlled trial?]
    Xavier Bosch
    Rev Esp Cardiol 58:333-7. 2005
  74. ncbi request reprint Spain makes plans to combat sex tourism
    Xavier Bosch
    Lancet 363:542. 2004
  75. ncbi request reprint New risk score for patients with acute chest pain, non-ST-segment deviation, and normal troponin concentrations: a comparison with the TIMI risk score
    Juan Sanchis
    Servei de Cardiologia, Hospital Clinic Universitari, Universitat de Valencia, Valencia, Spain
    J Am Coll Cardiol 46:443-9. 2005
    ..The purpose of this research was to develop a risk score for patients with chest pain, non-ST-segment deviation electrocardiogram (ECG), and normal troponin levels...
  76. ncbi request reprint Usefulness of early exercise testing and clinical risk score for prognostic evaluation in chest pain units without preexisting evidence of myocardial ischemia
    Juan Sanchis
    Servei de Cardiologia, Hospital Clinic Universitari, Valencia, Spain
    Am J Cardiol 97:633-5. 2006
    ..2 to 2.9, p = 0.003) end points. In conclusion, if a policy of invasive management is implemented for patients with positive exercise test results, the clinical risk score constitutes the main prognostic predictor of 1-year outcome...
  77. ncbi request reprint Prognostic value of clinical variables at presentation in patients with non-ST-segment elevation acute coronary syndromes: results of the Proyecto de Estudio del Pronóstico de la Angina (PEPA)
    Esteban Lopez de Sa
    Hospital General U Gregorio Marañón, Madrid, Spain
    Medicine (Baltimore) 81:434-42. 2002
    ....
  78. ncbi request reprint [English edition of the Revista Española de Cardiología on the Internet. A new big step forward]
    Xavier Bosch
    Rev Esp Cardiol 55:1-3. 2002
  79. ncbi request reprint [Clinical characteristics, prognosis, and variability in the management of non-ST-segment elevation acute coronary syndromes. Data from the PEPA registry]
    Xavier Bosch
    Servicio de Cardiología Institut de Malalties Cardiovasculars Hospital Clínic Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS Barcelona España
    Rev Esp Cardiol 56:346-53. 2003
    ..To assess the clinical characteristics and inter-hospital variability in the treatment and prognosis of patients with non-ST-segment elevation acute coronary syndromes...
  80. ncbi request reprint Limitations of clinical history for evaluation of patients with acute chest pain, non-diagnostic electrocardiogram, and normal troponin
    Juan Sanchis
    Servei de Cardiologia, Hospital Clinic Universitari, Universitat de Valencia, Valencia, Spain
    Am J Cardiol 101:613-7. 2008
    ..Short-term outcomes, including revascularization, however, are not predicted as well. Therefore, ancillary tools, such as noninvasive stress tests, should be implemented for decision making at initial hospitalization or discharge...
  81. ncbi request reprint Relapsing catastrophic antiphospholipid syndrome: report of three cases
    Ronald A Asherson
    Division of Immunology, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa
    Semin Arthritis Rheum 37:366-72. 2008
    ..Relapses in patients with the CAPS are very uncommon...
  82. ncbi request reprint New website for Alzheimer's disease launched in Spain
    Xavier Bosch
    Lancet Neurol 2:3. 2003
  83. ncbi request reprint Marine ecology. Scientists brace for bad tidings after spill
    John Bohannon
    Science 298:1695. 2002
  84. ncbi request reprint Spanish centre for rehabilitation of multiple sclerosis to be built
    Xavier Bosch
    Lancet Neurol 2:391. 2003
  85. ncbi request reprint Exposure to oil spill has detrimental effect on clean-up workers' health
    Xavier Bosch
    Lancet 361:147. 2003
  86. ncbi request reprint Infectious diseases research boost
    Xavier Bosch
    Lancet Infect Dis 3:122. 2003
  87. ncbi request reprint [Clinical characteristics, management, and prognosis of patients with acute myocardial infarction not admitted to the coronary care unit. Usefulness of an intermediate care unit as the initial admission site]
    Xavier Bosch
    Institut de Malalties Cardiovasculars Hospital Clínic Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS Departament de Medicina Universitat de Barcelona Barcelona España
    Rev Esp Cardiol 56:262-70. 2003
    ..The aim of this study was to evaluate the characteristics and prognosis of the patients who were admitted to the intermediate care unit (INTCU) of a cardiology department...
  88. ncbi request reprint Accessibility to coronary angiography and one-year survival after myocardial infarction
    Fernando Aros
    Cardiologia, Hospital Txagorritxu, Vitoria, Spain
    Am J Cardiol 90:409-12. 2002
  89. pmc Controversial immunologist faces court case
    Xavier Bosch
    BMJ 324:695. 2002
  90. ncbi request reprint Catalan authorities investigate insurance fraud plot by doctors and lawyers
    Xavier Bosch
    Lancet 359:505. 2002
  91. pmc Spain to ban drinking in the street
    Xavier Bosch
    BMJ 324:446. 2002
  92. pmc Barcelona medical college runs certification system for websites
    Xavier Bosch
    BMJ 324:567. 2002
  93. ncbi request reprint Spain's regional government becomes first in Europe to sue tobacco industry
    Xavier Bosch
    Lancet 359:772. 2002
  94. ncbi request reprint Spain. New cancer center makes a big splash
    Xavier Bosch
    Science 295:1995. 2002
  95. ncbi request reprint [Intensive insulin therapy in non-diabetic patients with myocardial infarction and hyperglycemia. INSUCOR study]
    Begona Benito
    Servicio de Cardiologia, Instituto Clínico del Tórax, Barcelona, Espana
    Med Clin (Barc) 130:601-5. 2008
    ..The aim of our study was to assess the short-term effects and the safety of strict glycemic control in subjects with MI and hyperglycemia without a previous history of diabetes...
  96. ncbi request reprint Spain's drug industry agrees to ethical drug promotion behaviour
    Xavier Bosch
    Lancet 359:1926. 2002
  97. pmc Spain: old people frequently live with their families
    Xavier Bosch
    BMJ 324:1543. 2002
  98. ncbi request reprint [Why was our manuscript rejected?]
    Xavier Bosch
    Revista Española de Cardiología
    Rev Esp Cardiol 55:782-3. 2002
  99. ncbi request reprint Comprehensive genetic screening program started for Spanish patients with AD
    Xavier Bosch
    Lancet Neurol 1:466. 2002
  100. ncbi request reprint Spain's scientists granted new career choice
    Xavier Bosch
    Nat Med 9:980. 2003