José R Blesa

Summary

Country: Spain

Publications

  1. ncbi NRF-2 transcription factor is required for human TOMM20 gene expression
    José R Blesa
    Centro de Investigacion Principe Felipe, Laboratory of Cell Organization, Valencia, Spain
    Gene 391:198-208. 2007
  2. doi NRF-1 is the major transcription factor regulating the expression of the human TOMM34 gene
    José R Blesa
    Fundacion Centro de Investigacion Principe Felipe, Av Autopista del Saler 16 3, Valencia, Spain
    Biochem Cell Biol 86:46-56. 2008
  3. doi In vitro methylation of nuclear respiratory factor-2 binding sites suppresses the promoter activity of the human TOMM70 gene
    José R Blesa
    Centro de Investigación Príncipe Felipe Av Autopista del Saler 16 346012 Valencia, Spain
    Gene 427:58-64. 2008
  4. ncbi Distinct functional contributions of 2 GABP-NRF-2 recognition sites within the context of the human TOMM70 promoter
    José R Blesa
    Fundacion Centro de Investigacion Principe Felipe, Av Autopista del Saler 16 3, 46013 Valencia, Spain
    Biochem Cell Biol 84:813-22. 2006

Detail Information

Publications4

  1. ncbi NRF-2 transcription factor is required for human TOMM20 gene expression
    José R Blesa
    Centro de Investigacion Principe Felipe, Laboratory of Cell Organization, Valencia, Spain
    Gene 391:198-208. 2007
    ..The NRF-2 binding site is required to activate transcription. The proximal NRF-1 site cooperates with NRF-2 in regulating the expression of the gene. The distal NRF-1 binding site is not functional...
  2. doi NRF-1 is the major transcription factor regulating the expression of the human TOMM34 gene
    José R Blesa
    Fundacion Centro de Investigacion Principe Felipe, Av Autopista del Saler 16 3, Valencia, Spain
    Biochem Cell Biol 86:46-56. 2008
    ..We conclude that NRF-1 is the main transcription factor regulating the expression of TOMM34. Sp1 interacts with NRF-1 to stimulate the promoter's full activity...
  3. doi In vitro methylation of nuclear respiratory factor-2 binding sites suppresses the promoter activity of the human TOMM70 gene
    José R Blesa
    Centro de Investigación Príncipe Felipe Av Autopista del Saler 16 346012 Valencia, Spain
    Gene 427:58-64. 2008
    ..Since a number of nuclear genes encoding mitochondrial translocases have NRF-2 binding sequences containing CpG methylation sites, a possible role of methylation as a regulatory mechanism of mitochondrial biogenesis can be ruled out...
  4. ncbi Distinct functional contributions of 2 GABP-NRF-2 recognition sites within the context of the human TOMM70 promoter
    José R Blesa
    Fundacion Centro de Investigacion Principe Felipe, Av Autopista del Saler 16 3, 46013 Valencia, Spain
    Biochem Cell Biol 84:813-22. 2006
    ..Evidence is provided that they work in an additive manner as single sites...