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Species | Julian Benito-LeonSummaryCountry: Spain Publications
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Publications
Impaired health-related quality of life predicts progression of disability in multiple sclerosisJ Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Eur J Neurol 20:79-86. 2013..To determine the value of health-related quality of life (HRQOL) in predicting progression of disability in patients with multiple sclerosis (MS) over a period of 2 years...
Impact of apathy on health-related quality of life in recently diagnosed Parkinson's disease: the ANIMO studyJulian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Mov Disord 27:211-8. 2012..It should be one of the primary concerns among clinicians who provide treatment to individuals affected by PD...
Impact of fatigue in multiple sclerosis: the Fatigue Impact Scale for Daily Use (D-FIS)J Benito-Leon
Department of Neurology, Mostoles General Hospital, and Gregorio Marañón University, Madrid, Spain
Mult Scler 13:645-51. 2007..The Fatigue Impact Scale for Daily Use (D-FIS) is an eight-item instrument designed to measure subjective daily experience of fatigue. This study sought to determine the metric properties of the D-FIS in multiple sclerosis (MS) patients...
Elderly-onset essential tremor and mild cognitive impairment: a population-based study (NEDICES)Julian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Alzheimers Dis 23:727-35. 2011..73, 95% CI = 0.34 to 1.57, p = 0.43). In this study, older-onset ET was associated with MCI. This finding supports the hypothesis that cognitive disturbances are one of the core non-motor symptoms of ET...
Clinical update: diagnosis and treatment of essential tremorJulian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, E 28041 Madrid, Spain
Lancet 369:1152-4. 2007
Reported hearing impairment in essential tremor: a population-based case-control studyJulian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Neuroepidemiology 29:213-7. 2007..3; 95% confidence interval 1.01-1.7; p = 0.04). ET seemed to be associated with reported hearing impairment. The basis for this finding, which has been noted in several studies, deserves further exploration...
Essential tremor: emerging views of a common disorderJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Madrid, Spain
Nat Clin Pract Neurol 2:666-78; quiz 2p following 691. 2006..In addition, recent investigations of environmental toxicants that might be linked to ET open the way towards primary disease prevention through a reduction in exposure to these factors...
Elderly-onset essential tremor is associated with dementiaJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Madrid, Spain
Neurology 66:1500-5. 2006..To determine whether essential tremor (ET) is associated with prevalent dementia...
[Prophylactic treatment of migraine]Julian Benito-Leon
Servicio de Neurologia, Hospital General de Mostoles, Mostoles, Madrid, Spain
Med Clin (Barc) 126:467-72. 2006
Population-based case-control study of cognitive function in essential tremorJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Mostoles, Madrid, Spain
Neurology 66:69-74. 2006..To determine whether patients with essential tremor (ET) have cognitive deficits when compared with controls and whether the types of cognitive deficits reported previously are also found in this large sampling of patients with ET...
Guillain-Barré-like syndrome associated with olanzapine hypersensitivity reactionJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Madrid, Spain
Clin Neuropharmacol 28:150-1. 2005..The presence of progressive numbness, motor weakness, or pain in the limbs of patients receiving olanzapine should raise suspicion of Guillain-Barré syndrome...
Isolated CNS Whipple disease: acute onset and relapsing-remitting courseJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Mostoles, Madrid, Spain
Scand J Infect Dis 39:623-5. 2007..We describe 2 patients with isolated CNS WD who presented unusually with an acute onset followed by a relapsing-remitting course. Neither was diagnosed with WD until they had had several relapses...
The CAREQOL-MS was a useful instrument to measure caregiver quality of life in multiple sclerosisJulian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Clin Epidemiol 64:675-86. 2011..To develop and test the first specific instrument for assessing caregiver health-related quality of life (HRQOL) in multiple sclerosis (MS) (CAREQOL-MS)...
Total daily sleep duration and the risk of dementia: a prospective population-based studyJ Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Eur J Neurol 16:990-7. 2009..We determined in a population-based study whether sleep duration was associated with an increased risk of incident dementia...
Brain structural changes in essential tremor: voxel-based morphometry at 3-TeslaJulian Benito-Leon
Departamento de Neurologia, Hospital Universitario 12 de Octubre, Madrid, Spain
J Neurol Sci 287:138-42. 2009..Two voxel-based morphometry (VBM) studies, each using a 1.5-T magnet, evaluated ET patients, leading to contradictory results. Using a 3-T magnet, we assessed whether white or gray matter changes occurred in ET patients vs. controls...
Risk of incident Parkinson's disease and parkinsonism in essential tremor: a population based studyJ Benito-Leon
Department of Neurology, University Hospital, Madrid, Spain
J Neurol Neurosurg Psychiatry 80:423-5. 2009..A longstanding literature suggests an association between essential tremor (ET) and Parkinson's disease (PD). However, the risk of incident PD has not been quantified in cases of ET compared with controls...
Population-based case-control study of morale in Parkinson's diseaseJ Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Eur J Neurol 16:330-6. 2009..Parkinson's disease (PD) is associated with cognitive, psychiatric, and motor features. Each could contribute to a poor sense of well-being and low morale. A systematic study of morale in community-dwelling PD cases has not been performed...
Low morale is associated with increased risk of mortality in the elderly: a population-based prospective study (NEDICES)Julian Benito-Leon
The Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Age Ageing 39:366-73. 2010..the study aimed to assess the association between morale and mortality...
Association between multiple sclerosis and Candida species: evidence from a case-control studyJ Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Eur J Clin Microbiol Infect Dis 29:1139-45. 2010..0 (1.5-6.1, p = 0.002) for Candida glabrata. The results were similar after excluding ten patients on immunosuppressants. The results of this single study suggest that Candida species infection may be associated with increased odds of MS...
Isolated central nervous system Whipple's disease causing reversible frontotemporal-like dementiaJulian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Clin Neurol Neurosurg 110:747-9. 2008..Because Whipple's disease is treatable, it should be considered in the workup of patients with a FTD-like behavioural and cognitive syndrome...
A population-based study of cognitive function in older people with subjective memory complaintsJulian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Alzheimers Dis 22:159-70. 2010..Predictors of SMC may differ in those with versus without MCI and those with versus without depressive symptoms...
Population-based case-control study of cigarette smoking and essential tremorJulian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Mov Disord 23:246-52. 2008..22-0.69, P = 0.001). We demonstrated an inverse association between ever smoking and ET. Additional studies are needed to reproduce these findings and assess whether this association is due to a biologically protective effect...
Incidence of essential tremor in three elderly populations of central SpainJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Mostoles, Madrid, Spain
Neurology 64:1721-5. 2005..To estimate the incidence of essential tremor (ET) in three populations in central Spain using data from the Neurologic Disorders in Central Spain (NEDICES), a population-based survey of elderly subjects (65 years and older)...
Management of essential tremor, including medical and surgical approachesJulian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas CIBERNED, Madrid, Spain
Handb Clin Neurol 100:449-56. 2011..For severe tremor, deep-brain stimulation of the thalamus may improve function...
[Intracranial hypotension syndrome]J Benito-Leon
Servicios de Neurologia, Hospital General de Mostoles, Mostoles, Madrid, Spain
Neurologia 16:418-26. 2001..In this article, we review the clinical and neuroimaging findings, pathophysiology, and treatment of this syndrome...
[Backache as the initial symptom of adrenomyeloneuropathy]J Benito-Leon
Servicio de Neurologia, Hospital General de Mostoles, Mostoles, Madrid, Espana
Rev Neurol 31:1167-70. 2000..We describe a patient with adrenomyeloneuropathy in whom the presenting symptom was lumbago...
Health-related quality of life and its relationship to cognitive and emotional functioning in multiple sclerosis patientsJ Benito-Leon
Department of Neurology, Mostoles General Hospital, Madrid, Spain
Eur J Neurol 9:497-502. 2002..Furthermore, we also found significant correlations between cognitive and emotional functioning tests and HRQoL dimensions. Thus, the worse cognitive functioning and the higher depressive and anxiety symptoms score the lower the HRQoL...
Update on essential tremorJ Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Minerva Med 102:417-40. 2011..For severe, medically refractory ET, thalamic ventralis intermedius nucleus deep brain stimulation may lessen tremor and improve function...
Prevalence of PD and other types of parkinsonism in three elderly populations of central SpainJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Mostoles, Madrid, Spain
Mov Disord 18:267-74. 2003..Despite improvement in access to health services, an important proportion of PD patients may never seek neurological attention...
[Health-related quality of life in multiple sclerosis]J Benito-Leon
Seccion de Neurologia, Hospital General de Mostoles, Mostoles, Spain
Neurologia 18:210-7. 2003..In fact, HRQoL measurements in MS are becoming important in assessing the effect of treatment and progression of the disease. This article will provide a review of the most significant studies on HRQoL in MS...
[Ischemic stroke in children]J Benito-Leon
Servicio de Neurologia Infantil, Hospital Universitario 12 de Octubre, Madrid, Espana
Rev Neurol 27:631-4; discussion 634-5. 1998..Ischemic stroke in children and infants is a rare condition. We present a series of 23 pediatric patients of ischemic stroke...
Incidence of Parkinson disease and parkinsonism in three elderly populations of central SpainJ Benito-Leon
Department of Neurology, Mostoles General Hospital, Ministry of Labor and Social Affairs, Madrid, Spain
Neurology 62:734-41. 2004..The scarcity of statistics on the incidence of PD and other types of parkinsonism using this methodology led the authors to estimate them in three elderly populations...
Neurosyphilis masquerading as corticobasal degenerationJ Benito-Leon
Department of Neurology, Mostoles General Hospital, Mostoles, Madrid, Spain
Mov Disord 19:1367-70. 2004..Syphilis, "the great imitator," may also masquerade as CBD. Because neurosyphilis is treatable, it should be considered in the workup of patients with cognitive impairment and motor signs of CBD...
Combined quinacrine and chlorpromazine therapy in fatal familial insomniaJulian Benito-Leon
Service of Neurology, Mostoles General Hospital, Mostoles, Madrid, Spain
Clin Neuropharmacol 27:201-3. 2004..The objective of this paper was to report on 2 fatal familial insomnia patients whose overall condition worsened despite quinacrine and chlorpromazine treatment...
Rapidly deteriorating polyneuropathy associated with osteosclerotic myeloma responsive to intravenous immunoglobulin and radiotherapyJ Benito-Leon
Department of Neurology, Universitary Hospital 12 de Octubre, Madrid, Spain
J Neurol Sci 158:113-7. 1998..We describe a 49-year-old patient with rapidly deteriorating polyneuropathy associated with osteosclerotic myeloma, who responded favorably to a combination of intravenous immunoglobulin and radiotherapy...
Population-based case-control study of cognitive function in early Parkinson's disease (NEDICES)Julian Benito-Leon
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Neurol Sci 310:176-82. 2011..Population-based assessments of cognitive function in patients with early Parkinson's disease (PD) are rare. We examined whether patients with early PD have cognitive deficits when compared with matched controls..
Statins and cognitive functioning in the elderly: a population-based studyJuliín Benito-León
The Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Alzheimers Dis 21:95-102. 2010..In this population-based sample, elderly participants treated with statins and untreated controls performed similarly in all tested cognitive areas. These results do not support a positive benefit of statins on cognition...
Premotor cognitive status in a cohort of incident Parkinson disease patients (NEDICES)Alvaro Sánchez-Ferro
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Neurol Sci 310:211-5. 2011..We examined whether patients with incident PD had had global cognitive function disturbances three years prior to diagnosis when compared with matched controls in a cohort of community-dwelling subjects...
Dementia-associated mortality at thirteen years in the NEDICES Cohort StudyAlberto Villarejo
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Alzheimers Dis 26:543-51. 2011..Age, gender, and co-morbidity are associated with higher mortality in dementia patients. Almost one third of deaths in persons over 85 years-old could be attributable to dementia...
Prevalence of essential tremor in three elderly populations of central SpainJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Mostoles, Madrid, Spain
Mov Disord 18:389-94. 2003..Despite the variability in worldwide data, ET is a frequently encountered disorder in elderly people. Furthermore, as ET may be seen as a relatively benign condition, a large proportion of patients may never seek neurological attention...
Mortality from Parkinson's disease: a population-based prospective study (NEDICES)Ignacio J Posada
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Mov Disord 26:2522-9. 2011..40-4.90; P < .001). In this prospective population-based study, Parkinson's disease was an independent predictor of mortality in the elderly. Parkinson's disease patients with dementia had particularly high risks of mortality...
Health-related quality of life evaluation by proxy in Parkinson's disease: approach using PDQ-8 and EuroQoL-5DPablo Martinez-Martin
Neuroepidemiology Unit, National Centre for Epidemiology, Carlos III Institute of Public Health, Madrid, Spain
Mov Disord 19:312-8. 2004..The degree of agreement varied for individual dimensions. Proxy evaluation of PD patients' HRQoL showed limitations mainly with assessments using the EuroQoL and especially in patients with severe disease and depression...
Patients', doctors', and caregivers' assessment of disability using the UPDRS-ADL section: are these ratings interchangeable?Pablo Martinez-Martin
National Center for Epidemiology, Carlos III Institute of Public Health, Madrid, Spain
Mov Disord 18:985-92. 2003..In PD, UPDRS-section 2-based assessment of disability by patients themselves and caregivers is a valid and reliable outcome...
Clinical correlates of apathy in patients recently diagnosed with Parkinson's disease: the ANIMO studyEsther Cubo
Department of Neurology, Complejo Asistencial Universitario, Burgos, Spain
Neuroepidemiology 38:48-55. 2012..Little is known about apathy in the early stages of Parkinson's disease (PD). We determined the clinical correlates of apathy in a large representative sample of patients recently diagnosed with PD (ANIMO study)...
A review about the impact of multiple sclerosis on health-related quality of lifeJulian Benito-Leon
tment of Neurology, Mostoles General Hospital, Madrid, Spain
Disabil Rehabil 25:1291-303. 2003..Assessment of multiple sclerosis-specific health-related quality of life should be included in future clinical trials to provide a complete picture of patients' health status...
Memory impairment in a simple recall task increases mortality at 10 years in non-demented elderlyAlberto Villarejo
Department of Neurology, Hospital Universitario 12 de Octubre, Madrid, Spain
Int J Geriatr Psychiatry 26:182-7. 2011..To evaluate whether memory impairment detected in the three-word delayed recall task of the Mini-Mental State Examination (MMSE) increases the risk of mortality...
Impact of fatigue in Parkinson's disease: the Fatigue Impact Scale for Daily Use (D-FIS)Pablo Martinez-Martin
Unit of Neuroepidemiology, National Centre for Epidemiology, ISCIII, Madrid, The Spanish Network HOHSR, Spain
Qual Life Res 15:597-606. 2006..In PD, D-FIS is a consistent and valid measure for fatigue, a frequent symptom previously found to impair patients' HRQoL. Fatigue was also linked to depression and disability in this study...
Prevalence of dementia and major dementia subtypes in Spanish populations: a reanalysis of dementia prevalence surveys, 1990-2008Jesus de Pedro-Cuesta
National Centre for Epidemiology, CIBERNED and Alzheimer Disease Research Unit, Carlos III Institute of Public Health, Madrid, Spain
BMC Neurol 9:55. 2009..This study describes the prevalence of dementia and major dementia subtypes in Spanish elderly...
Cerebrovascular disease incidence in central Spain (NEDICES): a population-based prospective studyAntonio Martinez-Salio
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Neurol Sci 298:85-90. 2010....
Risk of incident dementia in drug-untreated arterial hypertension: a population-based studyFelix Bermejo-Pareja
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Alzheimers Dis 22:949-58. 2010..38, 95% CI =1.32–4.29, p=0.004). Results were similar for risk of AD. Our results suggest that drug-untreated hypertension may be an independent risk factor for dementia and AD in the elderly...
Quality of life of caregivers in Parkinson's diseasePablo Martinez-Martin
National Center for Epidemiology, Carlos III Institute of Public Health, Madrid, Spain
Qual Life Res 14:463-72. 2005..To assess the impact of PD on informal caregivers of patients and identify the main factors related to caregiver strain...
Caregiver burden in Parkinson's diseasePablo Martinez-Martin
Neuroepidemiology Unit, National Center for Epidemiology, Carlos III Institute of Public Health, Madrid, Spain
Mov Disord 22:924-31; quiz 1060. 2007..This study underscores the need to consider the impact of PD on caregivers' well-being...
[Neuropsychiatric disturbances in essential tremor]Andrés Labiano-Fontcuberta
Servicio de Neurologia, Hospital Universitario 12 de Octubre, Madrid, Espana
Med Clin (Barc) 138:171-6. 2012....
Risk of incident dementia in essential tremor: a population-based studyFelix Bermejo Pareja
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Mov Disord 22:1573-80. 2007..The basis for this dementia, which is not known, requires additional study...
Prevalence of tics in schoolchildren in central Spain: a population-based studyEsther Cubo
Department of Neurology, Hospital General Yague, Burgos, Spain
Pediatr Neurol 45:100-8. 2011..The most frequent diagnoses involved chronic motor tics (6.07%) and Tourette syndrome (5.26%). Tic disorders are common in childhood, and the use or nonuse of impairment criteria exerts a significant impact on tic prevalence estimates...
Anger in Parkinson's disease: a case-control studyYolanda Macías
Parkinson s Disease Association of Móstoles, Mostoles, Madrid, Spain
Mov Disord 23:195-9. 2008..Conclusions: PD patients showed lower levels of external expression of anger and higher levels of control of anger. Our results demonstrate another dimension to the stoic personality trait seen in PD...
Gait disorders of unknown cause in the elderly: Clinical and MRI findingsOriol Franch
Department of Neurology, Hospital Ruber Internacional, Madrid, Spain
J Neurol Sci 280:84-6. 2009..Disequilibrium of unknown cause in older people has been associated with white matter lesions on neuroimaging studies...
Methods and design of the baseline survey of the neurological disorders in Salamanca (NEDISA) cohort: a population-based study in Central-Western SpainJesus Cacho
Department of Neurology, Salamanca University Hospital, Salamanca, Spain
Neuroepidemiology 36:62-8. 2011..We assessed the epidemiology of stroke, cognitive disorders, essential tremor (ET), Parkinson's disease (PD) and restless legs syndrome...
Incidence and subtypes of dementia in three elderly populations of central SpainF Bermejo-Pareja
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Neurol Sci 264:63-72. 2008..To assess age-, gender, and subtype-specific incidence rates of dementia in three populations in central Spain using data from the Neurological Disorders in Central Spain (NEDICES), a population-based survey of elderly participants...
Does the combination of the MMSE and clock drawing test (mini-clock) improve the detection of mild Alzheimer's disease and mild cognitive impairment?Jesus Cacho
Department of Neurology, University Hospital of Salamanca, University of Salamanca, Salamanca, Spain
J Alzheimers Dis 22:889-96. 2010..It has a high interrater and test-retest reliability, can be quickly administered, and does not require major training...
Consistency of clinical diagnosis of dementia in NEDICES: A population-based longitudinal study in SpainF Bermejo-Pareja
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
J Geriatr Psychiatry Neurol 22:246-55. 2009..We evaluated the consistency of the clinical diagnosis of dementia over a period of 3 years of follow-up in a population-based, cohort study of older people in central Spain...
A review of the potential therapeutic role of statins in the treatment of Alzheimer's disease: current research and opinionAlvaro Sánchez-Ferro
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain Department of Medicine, Complutense University, Madrid, Spain Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain Instituto de Salud Carlos III, Madrid, Spain
Neuropsychiatr Dis Treat 9:55-63. 2013..Therefore, the role of statins as a therapy in this disorder may be of great interest. The aim of the present review is to summarize of the role of statins in the treatment of Alzheimer's disease...
Changes at the CYP2C locus and disruption of CYP2C8/9 linkage disequilibrium in patients with essential tremorCarmen Martinez
Department of Pharmacology and Psychiatry, Medical School, University of Extremadura, Badajoz, and Department of Medicine Neurology, Principe de Asturias Hospital, Alcala de Henares, Madrid, Spain
Neuromolecular Med 9:195-204. 2007..0001). These findings were independent of gender, age, age of onset, or clinical symptoms. These results suggest that alterations at the CYP2C gene locus are associated with the risk for ET...
Multifocal myoclonus induced by haloperidolCristina Domínguez
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Neurol Sci 30:385-6. 2009..We report the first case of a patient with severe Alzheimer's disease who presented with non-epileptic myoclonus just after haloperidol treatment was initiated...
Methods and demographic findings of the baseline survey of the NEDICES cohort: a door-to-door survey of neurological disorders in three communities from Central SpainJ M Morales
Department of Research, Ministry of Labour and Social Affairs, Madrid, Spain
Public Health 118:426-33. 2004..The survey was designed to study dementia, essential tremor, Parkinson's disease and stroke...
Widespread urticaria due to intramuscular interferon beta-1a therapy for multiple sclerosisCristina Guijarro
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Neurol Sci 32:309-11. 2011..Widespread urticaria complicating intramuscular INF-β-1a therapy in multiple sclerosis should be therefore added to the list of dermatological lesions associated with interferon therapy...
A variant of WEBINO syndrome after top of the basilar artery strokeFernando Sierra-Hidalgo
Department of Neurology, Hospital Universitario 12 de Octubre, Madrid, Spain
Clin Neurol Neurosurg 112:801-4. 2010....
Cognitive dysfunction in multiple sclerosis: methods and prevalence from the GEDMA StudyJ Olazaran
Neurology Clinic, Hermanos Sangro Specialist Medical Centre, Madrid, Spain
Eur Neurol 61:87-93. 2009..Its prevalence varies due to disease heterogeneity and methodological issues. A neuropsychological battery of intermediate size was designed for and explored in the screening of cognitive dysfunction in MS patients...
Selective memory impairment on an adapted Mini-Mental State Examination increases risk of future dementiaJ Olazaran
Neurology Clinic, CEP Hermanos Sangro, Madrid, Spain
Int J Geriatr Psychiatry 19:1173-80. 2004..To determine whether selective memory impairment (SMI) on an adapted Mini-Mental State Examination (aMMSE) test increases risk of future dementia in a population-based survey of central Spain...
[Serum pro-oxidant and antioxidant factors and risk of Parkinson's disease: population study]J A Molina Arjona
, Hospital 12 de Octubre, Madrid
Rev Neurol 29:12-5. 1999..CONCLUSIONS: These results confirm the previous findings of classic case-control studies, suggesting the absence of relationship of the studied values with the risk for Parkinson's disease...
Cutaneous mucinoses complicating interferon beta-1b therapyJulian Benito-Leon
Department of Neurology, Mostoles General Hospital, Mostoles, Madrid, Spain
Eur Neurol 47:123-4. 2002
Accuracy of MRI criteria for dissemination in space for the diagnosis of multiple sclerosis in patients with clinically isolated syndromesMaria Diaz-Sanchez
Department of Neurology, University Hospital Virgen del Rocio, Seville, Spain
Mult Scler 16:576-80. 2010..Swanton's criteria are simpler and more sensitive than Barkhof-Tintoré's criteria, with a slight decrease in specificity. These results reinforce their use in multiple sclerosis diagnosis...
Driving cost factors in adult outpatients with refractory epilepsy: a daily clinical practice in clinics of neurology in SpainPilar Peña
Department of Neurology, General University Hospital, Valencia, Spain
Epilepsy Res 83:133-43. 2009..To explore the association between patient-reported-outcomes measurements and costs in adult outpatients with drug refractory epilepsy (DRE) in Spain...
[The NEDICES cohort of the elderly. Methodology and main neurological findings]F Bermejo-Pareja
Hospital Universitario 12 de Octubre, Madrid, Espana
Rev Neurol 46:416-23. 2008..To summarise the methodological aspects and main findings of the NEDICES (Neurological Disorders in Central Spain) cohort study of the elderly population, with over 5000 participants...
[Paraneoplastic cerebellar degeneration with asymmetrical pan-cerebellar syndrome]J Porta-Etessam
Servicio de Neurologia Hospital Universitario 12 de Octubre, Madrid, Espana
Rev Neurol 26:1015-7. 1998..Different families of tumours are associated with this, particularly (in view of its frequency) oat cell pulmonary carcinoma, gynecological tumours and Hodgkin's lymphoma...
[Differentiation between cerebral abscesses and necrotic or cystic tumours by means of diffusion sequences]J Benito Leon
Servicio de Neuroradiología Hospital Rúber Internacional, Madrid, Espana
Rev Neurol 32:137-40. 2001..Recently it has been suggested that diffusion sequences may be useful in the differential diagnosis of a necrotic or cystic mass...
[Thalamic dementia due to infarct of the left thalamus and genum of the right internal capsule]J Porta-Etessam
Servicio de Neurologia Hospital Universitario 12 de Octubre, Madrid, 28041, Espana
Rev Neurol 33:1043-6. 2001..We report a case of dementia of acute onset involving the left thalamus and the genum of the right internal capsule...
[HTLV-I myelopathy: presentation of a new case]J Diaz-Guzman
Servicio de Neurologia, Hospital Doce de Octubre, Madrid, Espana
Rev Neurol 25:557-9. 1997..So far five cases of this illness have been detected in Spain, five of them in immigrants. We present a new case in Spain, with a characteristic chronic clinical picture...
Prevalence of stroke and transient ischemic attack in three elderly populations of central SpainJ Diaz-Guzman
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain
Neuroepidemiology 30:247-53. 2008....
