Llucia Alos

Summary

Country: Spain

Publications

  1. ncbi request reprint Adenosquamous carcinoma of the head and neck: criteria for diagnosis in a study of 12 cases
    L Alos
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Histopathology 44:570-9. 2004
  2. pmc Activation of the EGFR/ERK pathway in high-grade mucoepidermoid carcinomas of the salivary glands
    B Lujan
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Villarroel, 170, Barcelona 08036, Spain
    Br J Cancer 103:510-6. 2010
  3. doi request reprint Human papillomaviruses are identified in a subgroup of sinonasal squamous cell carcinomas with favorable outcome
    Llucia Alos
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Cancer 115:2701-9. 2009
  4. ncbi request reprint Immunoarchitecture of lymphoid tissue in HIV-infection during antiretroviral therapy correlates with viral persistence
    Llucia Alos
    Department of Pathology, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Spain
    Mod Pathol 18:127-36. 2005
  5. ncbi request reprint Expression of membrane-bound mucins (MUC1 and MUC4) and secreted mucins (MUC2, MUC5AC, MUC5B, MUC6 and MUC7) in mucoepidermoid carcinomas of salivary glands
    Llucia Alos
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain
    Am J Surg Pathol 29:806-13. 2005
  6. pmc Lymphoid tissue collagen deposition in HIV-infected patients correlates with the imbalance between matrix metalloproteinases and their inhibitors
    Alba Diaz
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
    J Infect Dis 203:810-3. 2011
  7. ncbi request reprint HIV-1 upregulates intercellular adhesion molecule-1 gene expression in lymphoid tissue of patients with chronic HIV-1 infection
    Marta Garrido
    Department of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    J Acquir Immune Defic Syndr 46:268-74. 2007
  8. ncbi request reprint Predictors of tonsillar tissue HIV-1 viral burden at baseline and after 1 year of antiretroviral therapy
    Pilar Navarrete
    Infectious Diseases Unit, Clinic Institute of Infectious Diseases and Immunology, Faculty of Medicine, University of Barcelona, Barcelona, Spain
    Antivir Ther 8:635-7. 2003
  9. doi request reprint Characterization of 1152 lesions excised over 10 years using total-body photography and digital dermatoscopy in the surveillance of patients at high risk for melanoma
    Gabriel Salerni
    Melanoma Unit, Dermatology Department, Hospital Clinic of Barcelona, IDIBAPS, Barcelona, Spain
    J Am Acad Dermatol 67:836-45. 2012
  10. ncbi request reprint Redistribution of FOXP3-positive regulatory T cells from lymphoid tissues to peripheral blood in HIV-infected patients
    Ana Mozos
    Hematopathology Section, Department of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    J Acquir Immune Defic Syndr 46:529-37. 2007

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Adenosquamous carcinoma of the head and neck: criteria for diagnosis in a study of 12 cases
    L Alos
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Histopathology 44:570-9. 2004
    ..In this study we report the clinicopathological results of 12 ASCs, with special attention to their histological and immunohistochemical characteristics in order to define this neoplasm more precisely...
  2. pmc Activation of the EGFR/ERK pathway in high-grade mucoepidermoid carcinomas of the salivary glands
    B Lujan
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Villarroel, 170, Barcelona 08036, Spain
    Br J Cancer 103:510-6. 2010
    ..High-grade tumours usually have an aggressive biological course and they require additional oncological treatment after surgery...
  3. doi request reprint Human papillomaviruses are identified in a subgroup of sinonasal squamous cell carcinomas with favorable outcome
    Llucia Alos
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Cancer 115:2701-9. 2009
    ..The role of human papillomavirus (HPV) in the pathogenesis of squamous cell carcinomas (SCCs) of the sinonasal tract and its clinicopathological implications were evaluated...
  4. ncbi request reprint Immunoarchitecture of lymphoid tissue in HIV-infection during antiretroviral therapy correlates with viral persistence
    Llucia Alos
    Department of Pathology, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Spain
    Mod Pathol 18:127-36. 2005
    ..However, these parameters studied in lymphoid tissue are not re-established completely, even after 36 months of highly active antiretroviral therapy...
  5. ncbi request reprint Expression of membrane-bound mucins (MUC1 and MUC4) and secreted mucins (MUC2, MUC5AC, MUC5B, MUC6 and MUC7) in mucoepidermoid carcinomas of salivary glands
    Llucia Alos
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain
    Am J Surg Pathol 29:806-13. 2005
    ..This mucin expression pattern can be useful for diagnostic purposes. Therefore, MUC1 expression is related to tumor progression and worse prognosis, whereas MUC4 expression is related to a better prognosis...
  6. pmc Lymphoid tissue collagen deposition in HIV-infected patients correlates with the imbalance between matrix metalloproteinases and their inhibitors
    Alba Diaz
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
    J Infect Dis 203:810-3. 2011
    ..047). To our knowledge, this is the first time that MMP/TIMP imbalance has been correlated with lymphoid tissue collagen deposition and incomplete immune recovery in HIV-infected patients, even after long-term antiretroviral treatment...
  7. ncbi request reprint HIV-1 upregulates intercellular adhesion molecule-1 gene expression in lymphoid tissue of patients with chronic HIV-1 infection
    Marta Garrido
    Department of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    J Acquir Immune Defic Syndr 46:268-74. 2007
    ..Our main objective was to study ICAM-1 expression in LT from HIV-1-infected persons and to correlate this expression with LT viral load and the immunoarchitecture alteration before and after highly active antiretroviral therapy (HAART)...
  8. ncbi request reprint Predictors of tonsillar tissue HIV-1 viral burden at baseline and after 1 year of antiretroviral therapy
    Pilar Navarrete
    Infectious Diseases Unit, Clinic Institute of Infectious Diseases and Immunology, Faculty of Medicine, University of Barcelona, Barcelona, Spain
    Antivir Ther 8:635-7. 2003
    ..No correlation was observed after 1 year of antiretroviral therapy. A protease inhibitor-containing regimen was the best predictor of good tonsillar tissue virological response...
  9. doi request reprint Characterization of 1152 lesions excised over 10 years using total-body photography and digital dermatoscopy in the surveillance of patients at high risk for melanoma
    Gabriel Salerni
    Melanoma Unit, Dermatology Department, Hospital Clinic of Barcelona, IDIBAPS, Barcelona, Spain
    J Am Acad Dermatol 67:836-45. 2012
    ..The combined use of total-body photography and digital dermatoscopy, named "two-step method of digital follow-up," allowed the detection of incipient melanoma as a result of dermatoscopic or macroscopic changes during follow-up...
  10. ncbi request reprint Redistribution of FOXP3-positive regulatory T cells from lymphoid tissues to peripheral blood in HIV-infected patients
    Ana Mozos
    Hematopathology Section, Department of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    J Acquir Immune Defic Syndr 46:529-37. 2007
    ..Design: Paired samples from lymphoid tissue and peripheral blood were simultaneously obtained from 27 HIV-infected patients (before and after highly active antiretroviral therapy [HAART]) and 6 controls...
  11. doi request reprint Ex vivo dermoscopy for biobank-oriented sampling of melanoma
    Joseph Malvehy
    Melanoma Unit, Department of Dermatology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain2Centro de Investigacion Biomedica en Red Enfermedades Raras, Instituto de Salud Carlos III, Barcelona, Spain
    JAMA Dermatol 149:1060-7. 2013
    ..In the era of targeted therapy for cancer, translational research identifying molecular targets in melanoma offers novel opportunities for potential new treatments...
  12. doi request reprint Pigmented spindle cell nevus: clues for differentiating it from spindle cell malignant melanoma. A comprehensive survey including clinicopathologic, immunohistochemical, and FISH studies
    Alba Diaz
    Department of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Spain
    Am J Surg Pathol 35:1733-42. 2011
    ..However, ancillary techniques such as proliferation antigen Ki-67, cyclin D1, survivin, and FISH can be useful as adjunctive tools...
  13. doi request reprint Assessment of migration of HIV-1-loaded dendritic cells labeled with 111In-oxine used as a therapeutic vaccine in HIV-1-infected patients
    Alba Ruiz
    Infectious Diseases Unit, Hospital Clinic, Villarroel 170, Barcelona, Spain
    Immunotherapy 1:347-54. 2009
    ..92, p = 0.03). If more than 20,000 ILDCs had migrated, they could have been detected. In future trials, a higher number of DCs or alternative methods should be used to assess the migration of DCs to lymph nodes...
  14. doi request reprint Factors associated with collagen deposition in lymphoid tissue in long-term treated HIV-infected patients
    Alba Diaz
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    AIDS 24:2029-39. 2010
    ..The factors associated with fibrosis in lymphoid tissue in long-term treated HIV-infected patients and their correlation with immune reconstitution were assessed...
  15. doi request reprint Early stages of melanoma on the limbs of high-risk patients: clinical, dermoscopic, reflectance confocal microscopy and histopathological characterization for improved recognition
    Cristina Carrera
    Department of Dermatology, Melanoma and Dermatopathology Units, Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain
    Acta Derm Venereol 91:137-46. 2011
    ..Although the biological behaviour of these incipient tumours remains uncertain, the most appropriate treatment seems to be recognition and proper excision...
  16. ncbi request reprint p16 overexpression identifies HPV-positive vulvar squamous cell carcinomas
    Monica Santos
    Department of Pathology, Hospital Clínic Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Am J Surg Pathol 30:1347-56. 2006
    ..Immunostaining for p16 is a reliable marker for HPV-positive VSSCs, which improves the results of histologic classification...
  17. ncbi request reprint Autologous elastic cartilage for laryngoplasty: histologic evaluation in a rabbit model
    Miguel Caballero
    Department of Otorhinolaryngology, Hospital Clinic of Barcelona, Barcelona, Spain
    Ann Otol Rhinol Laryngol 112:734-9. 2003
    ..Autologous auricular cartilage appears to be an appropriate material for type I thyroplasty procedures because of the low absorption rate...
  18. ncbi request reprint Therapeutic immunization with dendritic cells loaded with heat-inactivated autologous HIV-1 in patients with chronic HIV-1 infection
    Felipe Garcia
    Infectious Diseases Unit, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Spain
    J Infect Dis 191:1680-5. 2005
    ..This response was associated with changes in HIV-1-specific CD4(+) lymphoproliferative and CD8(+) T cell responses. These changes were not observed in a group of nonimmunized control patients...
  19. ncbi request reprint Inflammatory myofibroblastic tumor in the larynx: clinicopathologic features and histogenesis
    Jose Maria Guilemany
    Department of Otorhinolaryngology, Hospital Clinic, Barcelona, Barcelona ES 08036, Spain
    Acta Otolaryngol 125:215-9. 2005
    ..Immunohistochemical studies revealed positivity of spindle cells to vimentin, muscle-specific actin and smooth muscle actin. The patient showed no evidence of disease 24 months after surgery...
  20. ncbi request reprint High-risk human papillomavirus is transcriptionally active in a subset of sinonasal squamous cell carcinomas
    Ana B Larque
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Mod Pathol 27:343-51. 2014
    ..Immunostaining for p16 can be used as a surrogate marker to identify these tumors. ..
  21. ncbi request reprint Extranodal lymphoma originating from mucosa-associated lymphoid tissue of the nasopharynx
    Eduardo Prades
    Rhinology Unit, Department of Otorhinolaryngology, Hospital Clinic, Barcelona, Spain
    Acta Otolaryngol 123:1098-101. 2003
    ..After 48 months of follow-up there was no evidence of disease and a control MRI scan was normal. The prognosis of this type of tumour is unpredictable and there are too few cases to enable definitive conclusions to be drawn...
  22. ncbi request reprint Treatment of 125 sinonasal tumors: prognostic factors, outcome, and follow-up
    Jose L Blanch
    Department of Otorhinolaryngology, Hospital Clinic, Universidad de Barcelona, Spain
    Otolaryngol Head Neck Surg 131:973-6. 2004
    ..Sinonasal tumors have a poor survival, despite early diagnosis, radical surgical resection, and strict follow-up. Radiotherapy seems not to be clearly necessary in stage T1...
  23. ncbi request reprint TERT and AURKA Gene Copy Number Gains Enhance the Detection of Acral Lentiginous Melanomas by Fluorescence in Situ Hybridization
    Alba Diaz
    Department of Pathology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    J Mol Diagn 16:198-206. 2014
    ..015). Our results indicate that addition of specific FISH probes to the current probe could improve sensitivity for the diagnosis of acral melanomas. Further studies in larger numbers of cases are needed to validate these results. ..
  24. ncbi request reprint Gene single nucleotide polymorphism accumulation improves survival in advanced head and neck cancer patients treated with weekly paclitaxel
    Juan J Grau
    Oncology Department, Institut Clinic de Malalties Hemato Oncologiques, Hospital Clinic, University of Barcelona, Spain
    Laryngoscope 119:1484-90. 2009
    ..Single nucleotide polymorphisms (SNPs) of certain genes involved in drug metabolism correlate with survival...
  25. ncbi request reprint Orbitoethmoid aneurysmal bone cyst. Case report and literature review
    Jose Maria Guilemany
    Department of Otorhinolaryngology, Hospital Clinic, Barcelona, Spain
    Rhinology 42:164-6. 2004
    ..These findings are characteristic of aneurysmal bone cysts. After 30 months of postoperative follow-up the patient remains disease-free and asymptomatic...
  26. ncbi request reprint Peripheral primitive neuroectodermal tumour of the left maxillary sinus
    Isam Alobid
    Rhinology Unit, Department of Otorhinolaryngology, Hospital Clinic, Barcelona, Spain
    Acta Otolaryngol 123:776-8. 2003
    ..After 59 months of follow-up, the patient remained free of disease and a repeat MRI scan was normalized, with no sign of residual tumour...
  27. ncbi request reprint In vivo reflectance confocal microscopy to monitor the response of lentigo maligna to imiquimod
    Ivette Alarcón
    Dermatology Department, Melanoma Unit, Hospital Clinic of Barcelona, Barcelona, Spain Institut de Recerca Biomédica August Pi i Sunyer IDIBAPS, Barcelona, Spain
    J Am Acad Dermatol 71:49-55. 2014
    ..Reflectance confocal microscopy (RCM) is a noninvasive method that has not been validated for monitoring the treatment of LM with imiquimod...
  28. doi request reprint Methylthioadenosine phosphorylase inactivation depends on gene deletion in laryngeal squamous cell carcinoma
    Laura Conde
    Fundació Clínic per a la Recerca Biomèdica, Barcelona, Spain
    Histopathology 61:1082-8. 2012
    ..MTAP status could be important for tumour cell sensitivity to adjuvant chemotherapy. To our knowledge, there have been no reports to date on MTAP status in laryngeal carcinoma...
  29. ncbi request reprint Prognostic significance of surgical margins in transoral CO2 laser microsurgery for T1-T4 pharyngo-laryngeal cancers
    Jose L Blanch
    Department of Otorhinolaryngology Head and Neck Surgery, Hospital Clinic i Universitari, C Villarroel 170, 08036 Barcelona, Spain
    Eur Arch Otorhinolaryngol 264:1045-51. 2007
    ..028). Tumor involvement of the surgical margin was associated with higher rates of local relapse, distant metastasis and the necessity of salvage surgery, together with a lower specific actuarial survival rate...
  30. ncbi request reprint Particulate silicone for vocal fold augmentation: morphometric evaluation in a rabbit model
    Manuel Bernal-Sprekelsen
    Department of Otorhinolaryngology, Hospital Clinic, Barcelona, University of Barcelona, Barcelona, Spain
    Ann Otol Rhinol Laryngol 113:234-41. 2004
    ..The group with injection of PDMS yielded histologic images compatible with greater and more stable medialization than did the group with injection of PTFE...
  31. ncbi request reprint Intranuclear inclusions in fine needle aspirates of bronchial low grade mucoepidermoid carcinoma with clear cell change: a report of two cases
    Cleofe Romagosa
    Department of Pathology, Hospital Clinic, University of Barcelona, Spain
    Acta Cytol 46:57-60. 2002
    ..We encountered two cases displaying unusual cytologic features, including clear intranuclear inclusions...
  32. ncbi request reprint Epiglottitis and necrotizing fasciitis: a life-threatening complication of infectious mononucleosis
    Miguel Caballero
    Department of Otorhinolaryngology, Hospital Clinic and University of Barcelona, Barcelona, Spain
    Acta Otolaryngol 125:1130-3. 2005
    ..Serial CT or MRI scans are necessary to assess the development of the infection in the deep layers of the neck. Rapid medical treatment, extensive surgical debridement and intensive care are vital...
  33. doi request reprint The Kaiser's cancer revisited: was Virchow totally wrong?
    Antonio Cardesa
    Anatomia Patologica, Facultat de Medicina, Hospital Clinic, Universitat de Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, Villarroel 170, Barcelona, Spain
    Virchows Arch 458:649-57. 2011
    ..Our retrospective evaluation suggests that Virchow's detailed description of the Kaiser's cancer preceded the paper that contributed to the full understanding of HVC of the larynx by 110 years...
  34. pmc Immunological Function Restoration with Lopinavir/Ritonavir Versus Efavirenz Containing Regimens in HIV-Infected Patients: A Randomized Clinical Trial
    Berta Torres
    1 Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    AIDS Res Hum Retroviruses 30:425-33. 2014
    ..These data indicate that the differences in CD4(+) gain with different cART regimens are not immunologically meaningful and might explain the similar clinical efficacy of these regimens. ..
  35. ncbi request reprint Laryngeal solitary fibrous tumor treated with CO2 laser excision: case report
    Isam Alobid
    Department of Otorhinolaryngology, Hospital Clinic, C Villarroel 170, 08036, Barcelona, Spain
    Eur Arch Otorhinolaryngol 262:286-8. 2005
    ..The tumor was removed by transoral CO(2) laser surgery. The definitive diagnosis was obtained by immunohistochemical analysis that showed vimentin and CD34-positive cells. The patient remains free of tumor after 15 months of follow-up...
  36. ncbi request reprint Solitary fibrous tumour of the nasal cavity and paranasal sinuses
    Isam Alobid
    Rhinology Unit, Department of Otorhinolaryngology, Hospital Clinic, Barcelona, Spain
    Acta Otolaryngol 123:71-4. 2003
    ..To date, only 21 cases of SFT arising from the nasal cavity and paranasal sinuses have been reported in the literature...
  37. doi request reprint Correlation among Dermoscopy, Confocal Reflectance Microscopy, and Histologic Features of Melanoma and Basal Cell Carcinoma Collision Tumor
    Gabriel Salerni
    Melanoma Unit, Department of Dermatology Department of Pathology Biochemistry and Molecular Genetics Service, Hospital Clinic of Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Dermatol Surg 37:275-9. 2011
    ..The authors have indicated no significant interest with commercial supporters...
  38. doi request reprint Alveolar soft part sarcoma presenting with cutaneous metastases: report of a case with immunohistochemical and molecular characterization
    Susana Moyano
    Department of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Villarroel 170, Barcelona, Spain
    J Am Acad Dermatol 61:117-20. 2009
    ..Cutaneous metastases presenting as the first sign of ASPS have not been reported previously. We emphasize the difficulties in making the diagnosis of ASPS when it presents in an unusual manner...
  39. doi request reprint Laryngeal squamous cell carcinoma in HIV-positive patients: lack of association with human papillomavirus infection
    S Moyano
    Departments of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    HIV Med 10:634-9. 2009
    ....