Cristina Alenda

Summary

Country: Spain

Publications

  1. ncbi request reprint Secretory carcinoma of the male breast: correlation of aspiration cytology and pathology
    Cristina Alenda
    Department of Pathology, Hospital General Universitario de Alicante, Alicante, Spain
    Diagn Cytopathol 32:47-50. 2005
  2. pmc Evidence for classification of c.1852_1853AA>GC in MLH1 as a neutral variant for Lynch syndrome
    Adela Castillejo
    Laboratorio Investigacion, Hospital Universitario Elche, Elche, Spain
    BMC Med Genet 12:12. 2011
  3. ncbi request reprint Hepatotoxicity related to paraquat and diquat absorption through intact skin
    Ana M Peiró
    Clinical Pharmacology Unit, Hospital General de Alicante, Pintor Baeza, S N, 03010, Alicante, Spain
    Dig Dis Sci 52:3282-4. 2007
  4. pmc Detection of BRAF V600E mutation in colorectal cancer: comparison of automatic sequencing and real-time chemistry methodology
    Susana Benlloch
    Unidad de Investigacion, Hospital General Universitario de Alicante, C Maestro Alonso 109, 03010 Alicante, Spain
    J Mol Diagn 8:540-3. 2006
  5. ncbi request reprint Analysis of HER2 by chromogenic in situ hybridization and immunohistochemistry in lymph node-negative breast carcinoma: Prognostic relevance
    Gloria Peiro
    Research Unit, Hospital General Universitari d Alacant, 03010 Alacant, Spain
    Hum Pathol 38:26-34. 2007
  6. doi request reprint The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status
    Rodrigo Jover
    Unidad de Gastroenterologia, Hospital General Universitario de Alicante, Alicante, Spain
    Eur J Cancer 45:365-73. 2009
  7. pmc Utility of p16 immunohistochemistry for the identification of Lynch syndrome
    Artemio Paya
    Unidad de Investigacion, Hospital General Universitario de Alicante, Alicante, Spain
    Clin Cancer Res 15:3156-62. 2009
  8. ncbi request reprint Immunohistochemical analysis of tumor angiogenic factors in human pituitary adenomas
    Maria Niveiro
    Department of Pathology, General Universitary Hospital of Alicante, Pintor Baeza s n, 03010 Alicante, Spain
    Hum Pathol 36:1090-5. 2005
  9. pmc Methylation analysis of MLH1 improves the selection of patients for genetic testing in Lynch syndrome
    Lucía Pérez-Carbonell
    Unidad de Investigacion, Hospital General Universitario de Alicante, Pintor Baeza 12, 03010 Alicante, Spain
    J Mol Diagn 12:498-504. 2010
  10. ncbi request reprint Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway
    Xavier Llor
    Gastroenterology Department, Germans Trias i Pujol Hospital, Universitat Autonoma de Barcelona, Spain
    Clin Cancer Res 11:7304-10. 2005

Collaborators

  • Rodrigo Jover
  • Antoni Castells
  • Montserrat Andreu
  • Xavier Llor
  • Gloria Peiro
  • Pedro Zapater
  • Susana Benlloch
  • Alfredo Carrato
  • Jose Such
  • Gregory H Enders
  • J P Gisbert
  • M Esteller
  • Beatriz Bellosillo
  • Artemio Paya
  • Xavier Bessa
  • Sergi Castellvi-Bel
  • Rosa M Xicola
  • Elisenda Pons
  • Francesc Balaguer
  • Adela Castillejo
  • Virginia Piñol
  • Lucía Pérez-Carbonell
  • Jose Luis Soto
  • Belén Ballesté
  • Francisco Rodriguez-Moranta
  • Victor M Barbera
  • Estefanía Rojas
  • Carmen Guillen
  • Clara Ruiz-Ponte
  • Angel Carracedo
  • Luis Bujanda
  • Victoria Gonzalo
  • Josep M Pique
  • Jenifer Muñoz
  • Rafael de Cid
  • Ana M Peiró
  • Maria Niveiro
  • Cecilia Egoavil
  • Maria Isabel Castillejo
  • Angel Segura
  • Ana Martinez-Canto
  • Victor Manuel Barbera
  • Carla Guarinos
  • Rafael Lazaro
  • Ana Beatriz Sanchez-Heras
  • Juan Clofent
  • Enrique Ochoa
  • Nuria Acame
  • Francisco J Gutiérrez-Aviñó
  • Jim Koh
  • Llucia Tito
  • Mercedes Martinez-Villacampa
  • Angels Vilella
  • Anna Giros
  • Miguel Perez-Mateo
  • José M Duque
  • Luisa de Castro
  • Miquel A Gassull
  • Ferran Fernandez-Bañares
  • Rosa Ma Xicola
  • Josep Maria Reñé
  • Carmen Cordero
  • Ana M Garcia
  • David Nicolas-Perez
  • Ana Ramirez
  • Ana Gutierrez
  • Joaquin Rigau
  • Lídia Argüello
  • Juan Diego Morillas
  • Joaquin Cubiella
  • F Ignacio Aranda
  • Antonio Pico

Detail Information

Publications19

  1. ncbi request reprint Secretory carcinoma of the male breast: correlation of aspiration cytology and pathology
    Cristina Alenda
    Department of Pathology, Hospital General Universitario de Alicante, Alicante, Spain
    Diagn Cytopathol 32:47-50. 2005
    ..Most cells contained intracytoplasmic vacuoles, which are the key feature of an accurate diagnosis. Differential diagnosis with other tumors is discussed briefly...
  2. pmc Evidence for classification of c.1852_1853AA>GC in MLH1 as a neutral variant for Lynch syndrome
    Adela Castillejo
    Laboratorio Investigacion, Hospital Universitario Elche, Elche, Spain
    BMC Med Genet 12:12. 2011
    ..Reports on the pathogenicity of the c.1852_1853AA>GC (p.Lys618Ala) variant of the MLH1 gene are conflicting. In this study, we provide new evidence indicating that this variant has no significant implications for LS...
  3. ncbi request reprint Hepatotoxicity related to paraquat and diquat absorption through intact skin
    Ana M Peiró
    Clinical Pharmacology Unit, Hospital General de Alicante, Pintor Baeza, S N, 03010, Alicante, Spain
    Dig Dis Sci 52:3282-4. 2007
  4. pmc Detection of BRAF V600E mutation in colorectal cancer: comparison of automatic sequencing and real-time chemistry methodology
    Susana Benlloch
    Unidad de Investigacion, Hospital General Universitario de Alicante, C Maestro Alonso 109, 03010 Alicante, Spain
    J Mol Diagn 8:540-3. 2006
    ..Because real-time chemistry methodology has advantages in cost, time, and labor, we consider it a valuable alternative to automatic direct sequencing, particularly for serial measurements...
  5. ncbi request reprint Analysis of HER2 by chromogenic in situ hybridization and immunohistochemistry in lymph node-negative breast carcinoma: Prognostic relevance
    Gloria Peiro
    Research Unit, Hospital General Universitari d Alacant, 03010 Alacant, Spain
    Hum Pathol 38:26-34. 2007
    ..Moreover, CISH is a valuable tool for the assessment of HER2 gene status with potential prognostic value and, therefore, in clinical decision making for treatment of high-risk LNNBC...
  6. doi request reprint The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status
    Rodrigo Jover
    Unidad de Gastroenterologia, Hospital General Universitario de Alicante, Alicante, Spain
    Eur J Cancer 45:365-73. 2009
    ..The aim of this study is to evaluate if mismatch repair (MMR) defective colorectal cancer has a different response to adjuvant 5-fluorouracil (5-FU) chemotherapy in a cohort of patients prospectively followed during 5 years...
  7. pmc Utility of p16 immunohistochemistry for the identification of Lynch syndrome
    Artemio Paya
    Unidad de Investigacion, Hospital General Universitario de Alicante, Alicante, Spain
    Clin Cancer Res 15:3156-62. 2009
    ..These tumors can also show epigenetic silencing of other genes, such as p16. The aim of our study is to evaluate the utility of p16 immunohistochemistry in the prediction of MLH1 germline mutations...
  8. ncbi request reprint Immunohistochemical analysis of tumor angiogenic factors in human pituitary adenomas
    Maria Niveiro
    Department of Pathology, General Universitary Hospital of Alicante, Pintor Baeza s n, 03010 Alicante, Spain
    Hum Pathol 36:1090-5. 2005
    ..Moreover, Flk-1 is associated with a more aggressive phenotype, and it may have potential therapeutic interest...
  9. pmc Methylation analysis of MLH1 improves the selection of patients for genetic testing in Lynch syndrome
    Lucía Pérez-Carbonell
    Unidad de Investigacion, Hospital General Universitario de Alicante, Pintor Baeza 12, 03010 Alicante, Spain
    J Mol Diagn 12:498-504. 2010
    ..Taken together, methylation analysis of MLH1 shows better performance characteristics than BRAF V600E mutation in the selection of patients for genetic testing of MLH1, especially when using MS-MLPA...
  10. ncbi request reprint Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway
    Xavier Llor
    Gastroenterology Department, Germans Trias i Pujol Hospital, Universitat Autonoma de Barcelona, Spain
    Clin Cancer Res 11:7304-10. 2005
    ..The main objectives of this study were to assess the relevance of clinically defined HNPCC patients without characteristic mutator pathway alterations and to identify their specific features...
  11. ncbi request reprint A prospective, multicenter, population-based study of BRAF mutational analysis for Lynch syndrome screening
    Xavier Bessa
    Department of Gastroenterology, Hospital del Mar, Barcelona, Catalonia, Spain
    Clin Gastroenterol Hepatol 6:206-14. 2008
    ..The aim of this study was to evaluate the contribution of BRAF V600E mutation analysis in the identification of MSH2/MLH1 gene mutation carriers in newly diagnosed CRC patients...
  12. ncbi request reprint Detection of metachronous neoplasms in colorectal cancer patients: identification of risk factors
    Belén Ballesté
    Gastroenterology Department, Hospital del Mar, and University of Barcelona, Spain
    Dis Colon Rectum 50:971-80. 2007
    ..This study was designed to identify individual and familial factors associated with the development of metachronous colorectal neoplasms in patients with colorectal cancer...
  13. ncbi request reprint Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer
    Sergi Castellvi-Bel
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBER EHD, IDIBAPS, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Carcinogenesis 28:1687-91. 2007
    ..23, P = 0.007) and familial cases and controls (OR = 1.55, 95% CI = 1.10-2.19, P = 0.01) in agreement with a hypothetical moderate increase of the cancer risk linked to the C148R ARLTS1 variant, both in sporadic and familial CRC cases...
  14. ncbi request reprint Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study
    Francesc Balaguer
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBERehd, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
    Clin Gastroenterol Hepatol 5:379-87. 2007
    ....
  15. ncbi request reprint Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors
    Rosa M Xicola
    Department of Gastroenterology, Germans Trias i Pujol Hospital, Carretera del Canyet s n, 08916 Badalona, Barcelona, Spain
    J Natl Cancer Inst 99:244-52. 2007
    ....
  16. ncbi request reprint Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations
    Francisco Rodriguez-Moranta
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Am J Gastroenterol 101:1104-11. 2006
    ..For this purpose, the National Cancer Institute outlined a set of recommendations, the Bethesda guidelines, which have recently been revised...
  17. ncbi request reprint Cyclooxygenase 2 expression in colorectal cancer with DNA mismatch repair deficiency
    Antoni Castells
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona
    Clin Cancer Res 12:1686-92. 2006
    ..Aim: To assess COX-2 expression in a large series of fully characterized colorectal cancer patients with respect to the MMR system and to dissect the mechanisms responsible for altered COX-2 expression in this setting...
  18. ncbi request reprint Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer
    Virginia Piñol
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, University of Barcelona, Barcelona, Spain
    JAMA 293:1986-94. 2005
    ..Recently, the National Cancer Institute outlined a new set of recommendations, the revised Bethesda guidelines, for the identification of individuals with HNPCC who should be tested for microsatellite instability...
  19. ncbi request reprint Defective mismatch-repair colorectal cancer: clinicopathologic characteristics and usefulness of immunohistochemical analysis for diagnosis
    Rodrigo Jover
    Department of Gastroenterology, General University Hospital of Alicante, Spain
    Am J Clin Pathol 122:389-94. 2004
    ..3%]; P = .05). There were no differences in age, family history of cancer, or TNM stage. Immunohistochemical analysis seems to be a reliable method to detect most colorectal cancers with defective MMR genes...