Antonio Alcina

Summary

Country: Spain

Publications

  1. pmc High ACSL5 transcript levels associate with systemic lupus erythematosus and apoptosis in Jurkat T lymphocytes and peripheral blood cells
    Antonio Catalá-Rabasa
    Department of Cell Biology and Immunology, Instituto de Parasitologia y Biomedicina Lopez Neyra Consejo Superior de Investigaciones Cientificas, Granada, Spain
    PLoS ONE 6:e28591. 2011
  2. pmc IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D)
    Antonio Alcina
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain
    PLoS ONE 4:e4137. 2009
  3. pmc Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations
    Antonio Alcina
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Científicas IPBLN CSIC, Granada, Spain
    PLoS ONE 7:e29819. 2012
  4. pmc Role of the small GTPase Rab27a during herpes simplex virus infection of oligodendrocytic cells
    Raquel Bello-Morales
    Centro de Biologia Molecular Severo Ochoa, CSIC UAM, Nicolás Cabrera 5, Cantoblanco, 28049, Madrid, Spain
    BMC Microbiol 12:265. 2012
  5. doi request reprint The high producer variant of the Fc-receptor like-3 (FCRL3) gene is involved in protection against multiple sclerosis
    Fuencisla Matesanz
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain
    J Neuroimmunol 195:146-50. 2008
  6. pmc Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis
    Antonio Alcina
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain
    Eur J Hum Genet 18:827-31. 2010
  7. ncbi request reprint Effects of the multiple sclerosis associated -330 promoter polymorphism in IL2 allelic expression
    Fuencisla Matesanz
    Instituto de Parasitologia y Biomedicina Lopez Neyra, CSIC, C Ventanilla 11, 18001 Granada, Spain
    J Neuroimmunol 148:212-7. 2004
  8. pmc Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis
    Antonio Alcina
    Department of Cell Biology and Immunology, Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain
    Eur J Hum Genet 18:618-20. 2010
  9. pmc Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis
    Antonio Alcina
    Department of Cell Biology and Immunology Instituto de Parasitología y Biomedicina López Neyra, Consejo Superior de Investigaciones Científicas IPBLNCSIC, Granada, Spain
    J Med Genet 50:25-33. 2013
  10. ncbi request reprint Lack of association between -384 and 114 IL-2 gene polymorphisms and rheumatoid arthritis
    Maria Fedetz
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Granada, Spain
    J Rheumatol 30:435-7. 2003

Collaborators

Detail Information

Publications11

  1. pmc High ACSL5 transcript levels associate with systemic lupus erythematosus and apoptosis in Jurkat T lymphocytes and peripheral blood cells
    Antonio Catalá-Rabasa
    Department of Cell Biology and Immunology, Instituto de Parasitologia y Biomedicina Lopez Neyra Consejo Superior de Investigaciones Cientificas, Granada, Spain
    PLoS ONE 6:e28591. 2011
    ..The aim of this work was to assess among the ACSL isoforms the involvement of ACSL2, ACSL4 and ACSL5 in SLE pathogenesis...
  2. pmc IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D)
    Antonio Alcina
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain
    PLoS ONE 4:e4137. 2009
    ..IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity...
  3. pmc Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations
    Antonio Alcina
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Científicas IPBLN CSIC, Granada, Spain
    PLoS ONE 7:e29819. 2012
    ..Our data suggest that the DR/DQ expression levels, together with specific structural properties of alleles, seem to be the causal effect in MS and in other immunopathologies rather than specific antigen presentation alone...
  4. pmc Role of the small GTPase Rab27a during herpes simplex virus infection of oligodendrocytic cells
    Raquel Bello-Morales
    Centro de Biologia Molecular Severo Ochoa, CSIC UAM, Nicolás Cabrera 5, Cantoblanco, 28049, Madrid, Spain
    BMC Microbiol 12:265. 2012
    ..Rab27a also seems to be required for human cytomegalovirus assembly. However, despite the involvement of various Rab GTPases in HSV-1 envelopment, there is, to date, no data reported on the role of Rab27a in HSV-1 infection...
  5. doi request reprint The high producer variant of the Fc-receptor like-3 (FCRL3) gene is involved in protection against multiple sclerosis
    Fuencisla Matesanz
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain
    J Neuroimmunol 195:146-50. 2008
    ..94; P-value = 0.007) as was the G variant of N28D, but no association was found for rs11264799/FCRL3_4. Haplotype analysis confirmed these associations with highly consistent effect sizes for haplotypes carrying the C allele of FCRL3_3...
  6. pmc Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis
    Antonio Alcina
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain
    Eur J Hum Genet 18:827-31. 2010
    ..Our findings agree with the corresponding data of the recent IMSGC study and present new genetic evidence that points to EVI5 as a factor of susceptibility to MS...
  7. ncbi request reprint Effects of the multiple sclerosis associated -330 promoter polymorphism in IL2 allelic expression
    Fuencisla Matesanz
    Instituto de Parasitologia y Biomedicina Lopez Neyra, CSIC, C Ventanilla 11, 18001 Granada, Spain
    J Neuroimmunol 148:212-7. 2004
    ..Our data show an increased IL2 expression among GT and TT genotypes previously associated with susceptibility to MS...
  8. pmc Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis
    Antonio Alcina
    Department of Cell Biology and Immunology, Instituto de Parasitologia y Biomedicina Lopez Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain
    Eur J Hum Genet 18:618-20. 2010
    ..This study corroborates the association of one locus determined by GWAS and points to H6PD as a new candidate gene for MS...
  9. pmc Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis
    Antonio Alcina
    Department of Cell Biology and Immunology Instituto de Parasitología y Biomedicina López Neyra, Consejo Superior de Investigaciones Científicas IPBLNCSIC, Granada, Spain
    J Med Genet 50:25-33. 2013
    ..The authors sought to identify the functional variant of this region associated with MS...
  10. ncbi request reprint Lack of association between -384 and 114 IL-2 gene polymorphisms and rheumatoid arthritis
    Maria Fedetz
    Instituto de Parasitologia y Biomedicina Lopez Neyra, Granada, Spain
    J Rheumatol 30:435-7. 2003
    ..To investigate the association of 2 single nucleotide polymorphisms (SNP) at positions -384 and 114 in the human interleukin 2 (IL-2) gene with susceptibility to and severity of rheumatoid arthritis (RA)...
  11. ncbi request reprint The Plasmodium falciparum fatty acyl-CoA synthetase family (PfACS) and differential stage-specific expression in infected erythrocytes
    Fuencisla Matesanz
    Department of Immunology and Cellular Biology, Instituto de Parasitologia y Biomedicina Lopez Neyra, CSIC, C Ventanilla 11, Granada 18001, Spain
    Mol Biochem Parasitol 126:109-12. 2003