Agustin Albillos

Summary

Country: Spain

Publications

  1. doi Role of endoscopy in primary prophylaxis for esophageal variceal bleeding
    Agustin Albillos
    Hospital Universitario Ramon y Cajal, Universidad de Alcala, Madrid, Spain
    Clin Liver Dis 14:231-50. 2010
  2. ncbi Secondary prophylaxis for esophageal variceal bleeding
    Agustin Albillos
    Department of Gastroenterology and Hepatology, Hospital Universitario Ramon y Cajal, CIBERehd, IRYCIS, University of Alcala, Ctra Colmenar km 9 100, Madrid 28034, Spain Electronic address
    Clin Liver Dis 18:359-70. 2014
  3. doi The biological response modifier AM3 attenuates the inflammatory cell response and hepatic fibrosis in rats with biliary cirrhosis
    Agustin Albillos
    Departamento de Medicina, Facultad de Medicina Campus Universitario, Universidad de Alcala, Carretera Madrid Barcelona Km 33 600, Alcala de Henares, Madrid, Spain
    Gut 59:943-52. 2010
  4. pmc Classification of cirrhosis: the clinical use of HVPG measurements
    Agustín Albilllos
    Department of Gastoenterology and Hepatology, Hospital Ramon y Cajal, Madrid, Spain
    Dis Markers 31:121-8. 2011
  5. ncbi Preventing first variceal hemorrhage in cirrhosis
    Agustin Albillos
    Servicio de Gastroenterologia, Hospital Universitario Ramon y Cajal, CIBERehd, Unidad I D Asociada al Centro Nacional de Biotecnología CSIC, Universidad Alcala, Madrid, Spain
    J Clin Gastroenterol 41:S305-11. 2007
  6. pmc The extent of the collateral circulation influences the postprandial increase in portal pressure in patients with cirrhosis
    Agustin Albillos
    Hospital Universitario Ramon y Cajal, Universidad de Alcala, Madrid, Spain
    Gut 56:259-64. 2007
  7. ncbi A meta-analysis of transjugular intrahepatic portosystemic shunt versus paracentesis for refractory ascites
    Agustin Albillos
    Servicio de Gastroenterologia, Hospital Universitario Ramon y Cajal, Departamento de Medicina, Universidad de Alcala, Madrid, Spain
    J Hepatol 43:990-6. 2005
  8. ncbi Serum lipopolysaccharide-binding protein prediction of severe bacterial infection in cirrhotic patients with ascites
    Agustin Albillos
    Laboratorio de Enfermedades del Sistema Inmune y Oncología, Unidad I D Asociada al CSIC, Departamento de Medicina, Universidad de Alcala, Carretera Madrid Barcelona, Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    Lancet 363:1608-10. 2004
  9. ncbi Tumour necrosis factor-alpha expression by activated monocytes and altered T-cell homeostasis in ascitic alcoholic cirrhosis: amelioration with norfloxacin
    Agustin Albillos
    Laboratorio de Enfermedades del Sistema Inmune y Oncología, Unidad I D Asociada al Centro Nacional de Biotecnología, Departamento de Medicina, Universidad de Alcala, Alcala de Henares, Madrid, Spain
    J Hepatol 40:624-31. 2004
  10. ncbi Increased lipopolysaccharide binding protein in cirrhotic patients with marked immune and hemodynamic derangement
    Agustin Albillos
    Servicio de Gastroenterologia, Hospital Ramon y Cajal, Alcala de Henares, Madrid, Spain
    Hepatology 37:208-17. 2003

Collaborators

Detail Information

Publications25

  1. doi Role of endoscopy in primary prophylaxis for esophageal variceal bleeding
    Agustin Albillos
    Hospital Universitario Ramon y Cajal, Universidad de Alcala, Madrid, Spain
    Clin Liver Dis 14:231-50. 2010
    ..Primary prophylaxis to prevent the first bleeding episode in patients with cirrhosis and esophageal varices is therefore critically important in the management of patients with cirrhosis...
  2. ncbi Secondary prophylaxis for esophageal variceal bleeding
    Agustin Albillos
    Department of Gastroenterology and Hepatology, Hospital Universitario Ramon y Cajal, CIBERehd, IRYCIS, University of Alcala, Ctra Colmenar km 9 100, Madrid 28034, Spain Electronic address
    Clin Liver Dis 18:359-70. 2014
    ..TIPS is the rescue treatment, but it could be considered as first choice in patients that first bleed while on beta-blockers, those with contraindications to beta-blockers or with refractory ascites, and those with fundal varices. ..
  3. doi The biological response modifier AM3 attenuates the inflammatory cell response and hepatic fibrosis in rats with biliary cirrhosis
    Agustin Albillos
    Departamento de Medicina, Facultad de Medicina Campus Universitario, Universidad de Alcala, Carretera Madrid Barcelona Km 33 600, Alcala de Henares, Madrid, Spain
    Gut 59:943-52. 2010
    ..AM3 is a low-toxicity biological response modifier with regulatory effects on innate and adaptative immunity, and the ability to normalise the production of tumour necrosis factor alpha (TNFalpha)...
  4. pmc Classification of cirrhosis: the clinical use of HVPG measurements
    Agustín Albilllos
    Department of Gastoenterology and Hepatology, Hospital Ramon y Cajal, Madrid, Spain
    Dis Markers 31:121-8. 2011
    ..In consequence, portal pressure measurement by means of HVPG allows stratifying cirrhosis in stages with defined outcomes, prognosis, and management strategies...
  5. ncbi Preventing first variceal hemorrhage in cirrhosis
    Agustin Albillos
    Servicio de Gastroenterologia, Hospital Universitario Ramon y Cajal, CIBERehd, Unidad I D Asociada al Centro Nacional de Biotecnología CSIC, Universidad Alcala, Madrid, Spain
    J Clin Gastroenterol 41:S305-11. 2007
    ..However, no study has yet demonstrated that banding as rescue therapy in nonresponders lowers the risk of first bleeding and improves survival...
  6. pmc The extent of the collateral circulation influences the postprandial increase in portal pressure in patients with cirrhosis
    Agustin Albillos
    Hospital Universitario Ramon y Cajal, Universidad de Alcala, Madrid, Spain
    Gut 56:259-64. 2007
    ..In cirrhosis, repeated flares of portal pressure and collateral blood flow provoked by postprandial hyperaemia may contribute to variceal dilation and rupture...
  7. ncbi A meta-analysis of transjugular intrahepatic portosystemic shunt versus paracentesis for refractory ascites
    Agustin Albillos
    Servicio de Gastroenterologia, Hospital Universitario Ramon y Cajal, Departamento de Medicina, Universidad de Alcala, Madrid, Spain
    J Hepatol 43:990-6. 2005
    ..Meta-analysis designed to provide evidence-based guidance on the effect of TIPS and paracentesis on mortality and encephalopathy in cirrhotic patients with refractory ascites...
  8. ncbi Serum lipopolysaccharide-binding protein prediction of severe bacterial infection in cirrhotic patients with ascites
    Agustin Albillos
    Laboratorio de Enfermedades del Sistema Inmune y Oncología, Unidad I D Asociada al CSIC, Departamento de Medicina, Universidad de Alcala, Carretera Madrid Barcelona, Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    Lancet 363:1608-10. 2004
    ..49, 95% CI 1.42-14.1). Monitoring of serum lipopolysaccharide-binding protein could, therefore, help to target cirrhotic patients with ascites for antibiotic prophylaxis...
  9. ncbi Tumour necrosis factor-alpha expression by activated monocytes and altered T-cell homeostasis in ascitic alcoholic cirrhosis: amelioration with norfloxacin
    Agustin Albillos
    Laboratorio de Enfermedades del Sistema Inmune y Oncología, Unidad I D Asociada al Centro Nacional de Biotecnología, Departamento de Medicina, Universidad de Alcala, Alcala de Henares, Madrid, Spain
    J Hepatol 40:624-31. 2004
    ....
  10. ncbi Increased lipopolysaccharide binding protein in cirrhotic patients with marked immune and hemodynamic derangement
    Agustin Albillos
    Servicio de Gastroenterologia, Hospital Ramon y Cajal, Alcala de Henares, Madrid, Spain
    Hepatology 37:208-17. 2003
    ..Amelioration of these abnormalities by norfloxacin suggests the involvement of enteric bacteria or their products in the triggering of the process...
  11. ncbi Defective thymopoiesis and poor peripheral homeostatic replenishment of T-helper cells cause T-cell lymphopenia in cirrhosis
    Margaret Lario
    Departamento de Medicina, Universidad de Alcala, Madrid, Spain
    J Hepatol 59:723-30. 2013
    ..Little is known about the pathogenetic mechanisms involved in Th-cell depletion in cirrhosis. We investigated the mechanisms involved in circulating Th-cell lymphopenia in cirrhosis...
  12. ncbi Mesenteric Th1 polarization and monocyte TNF-alpha production: first steps to systemic inflammation in rats with cirrhosis
    Leticia Muñoz
    Laboratorio de Enfermedades del Sistema Inmune, Unidad I D Asociada al Centro Nacional de Biotecnología CSIC, Departamento de Medicina, Universidad de Alcala, 28871 Alcala de Henares, Madrid, Spain
    Hepatology 42:411-9. 2005
    ..Later, the recirculation of these activated effector immune cells into blood promotes systemic inflammation...
  13. doi Prognostic value of hepatic venous pressure gradient in patients with compensated chronic hepatitis C-related cirrhosis
    Diego Rincon
    Hepatic Hemodynamic Laboratory, Liver Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Scand J Gastroenterol 48:487-95. 2013
    ..The aim of this study was to identify predictors of decompensation in patients with compensated chronic hepatitis C (CHC)-related cirrhosis with and without esophageal varices (Baveno stages 1 and 2)...
  14. doi Interaction between intestinal dendritic cells and bacteria translocated from the gut in rats with cirrhosis
    Leticia Muñoz
    Departamento de Medicina, Universidad de Alcala, Madrid, Spain
    Hepatology 56:1861-9. 2012
    ..In cirrhotic rats, bowel decontamination with antibiotics eliminated Bact-DNA in MLNs and GBT, normalized the activation state and functions of CD103(+) -DCs, and increased their TNF-α production...
  15. ncbi Value of the hepatic venous pressure gradient to monitor drug therapy for portal hypertension: a meta-analysis
    Agustin Albillos
    Servicio de Gastroenterologia, Hospital Ramon y Cajal, Madrid, Spain
    Am J Gastroenterol 102:1116-26. 2007
    ..Our aim was to establish whether target HVPG reduction predicts variceal bleeding in cirrhotic patients receiving variceal bleeding prophylaxis...
  16. ncbi Meta-analysis: Combination endoscopic and drug therapy to prevent variceal rebleeding in cirrhosis
    Rosario Gonzalez
    Hospital Universitario Ramon y Cajal, Madrid, Spain
    Ann Intern Med 149:109-22. 2008
    ..Combining endoscopic therapy and beta-blockers may improve outcomes in patients with cirrhosis and bleeding esophageal varices...
  17. ncbi Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: a meta-analysis
    Rafael Bañares
    Gastroenterology Unit, Hospital General Gregorio Maranon, Department of Medicine, Universidad Complutense, Madrid, Spain
    Hepatology 35:609-15. 2002
    ..In conclusion, in patients with AVB, pharmacologic agents improve the efficacy of endoscopic therapy to achieve initial control of bleeding and 5-day hemostasis, yet fail to affect mortality...
  18. ncbi Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis
    Rafael Bañares
    Hepatic Hemodynamic Laboratory, Liver Unit, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Hepatology 36:1367-73. 2002
    ..However, its clinical applicability may be limited by its systemic hypotensive effects. Further trials are needed to confirm the therapeutic potential of carvedilol...
  19. ncbi Relationship between response to interferon-alpha and function of peripheral blood mononuclear cells in chronic hepatitis C patients
    Fatima Esquivel
    Department of Medicine, Hospital Principe de Asturias, University of Alcala, Madrid, Spain
    Dig Dis Sci 47:2154-62. 2002
    ..This suggests that an alteration of the immune system in these patients may underlie their inadequate response to antiviral therapy...
  20. ncbi Systemic, renal, and hepatic hemodynamic derangement in cirrhotic patients with spontaneous bacterial peritonitis
    Luis Ruiz-del-Arbol
    Liver Hemodynamic Unit, Department of Gastroenterology, Hospital Ramon y Cajal, University of Alcala de Henares, Madrid, Spain
    Hepatology 38:1210-8. 2003
    ..This occurs despite rapid resolution of infection and is associated with an extremely poor prognosis...
  21. doi Critical role of the liver in the induction of systemic inflammation in rats with preascitic cirrhosis
    María Úbeda
    Laboratory of Immune System Disease, Department of Medicine, University of Alcala, Alcala de Henares, Madrid Spain
    Hepatology 52:2086-95. 2010
    ..In addition, in compensated cirrhosis, bacterial DNA fragments reach the MLNs, where they elicit a local inflammatory response...
  22. doi Loss of surface antigens is a conserved feature of apoptotic lymphocytes from several mammalian species
    David Diaz
    Department of Medicine, University of Alcala, Madrid, Spain
    Cell Immunol 271:163-72. 2011
    ..These data suggest that the loss of expression of LAgs by apoptotic lymphocytes is a common and conserved feature of lymphocytes undergoing apoptosis in several mammalian species...
  23. doi Rebleeding prophylaxis improves outcomes in patients with hepatocellular carcinoma. A multicenter case-control study
    Cristina Ripoll
    Servicio de Aparato Digestivo, Hospital Universitario Gregorio Maranon, IISGM, CIBERehd, Universidad Complutense, Madrid, Spain
    Hepatology 58:2079-88. 2013
    ..001). Lack of prophylaxis increased rebleeding and mortality. On multivariate analysis Child-Pugh score, presence of HCC, portal vein thrombosis, and lack of secondary prophylaxis were predictors of death...
  24. doi Quantitative profile of lipid classes in blood by normal phase chromatography with evaporative light scattering detector: application in the detection of lipid class abnormalities in liver cirrhosis
    Laura Chamorro
    Servicio de Bioquimica Clinica, Hospital Universitario Ramon y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain
    Clin Chim Acta 421:132-9. 2013
    ..In the present work, we have optimized an HPLC method to quantify lipid classes in plasma and erythrocytes and applied it to samples from patients with cirrhosis...
  25. doi Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial
    Rafael Bañares
    Liver Unit, Hospital General Universitario Gregorio Maranon, IISGM, Medical School, Universidad Complutense, Madrid, Spain
    Hepatology 57:1153-62. 2013
    ..02) and bilirubin (P=0.001) and a more frequent improvement in HE (from grade II-IV to grade 0-I; 62.5% versus 38.2%; P=0.07) was observed in the MARS group. Severe adverse events were similar...