Nicola G A Abrescia

Summary

Country: Spain

Publications

  1. pmc From lows to highs: using low-resolution models to phase X-ray data
    David I Stuart
    Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, England
    Acta Crystallogr D Biol Crystallogr 69:2257-65. 2013
  2. pmc Structural and functional analyses of the interaction of archaeal RNA polymerase with DNA
    Magdalena N Wojtas
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Nucleic Acids Res 40:9941-52. 2012
  3. ncbi Structure unifies the viral universe
    Nicola G A Abrescia
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Annu Rev Biochem 81:795-822. 2012
  4. ncbi Combined approaches to study virus structures
    Daniel Badia-Martinez
    Structural Biology Unit, CICbioGUNE, CIBERehd, Bizkaia Technology Park, 48160, Derio, Spain
    Subcell Biochem 68:203-46. 2013
  5. pmc Mechanism of membranous tunnelling nanotube formation in viral genome delivery
    Bibiana Peralta
    Structural Biology Unit, CIC bioGUNE, CIBERehd, Derio, Spain
    PLoS Biol 11:e1001667. 2013
  6. doi Archaeal RNA polymerase: the influence of the protruding stalk in crystal packing and preliminary biophysical analysis of the Rpo13 subunit
    Magdalena Wojtas
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Biochem Soc Trans 39:25-30. 2011
  7. doi The use of low-resolution phasing followed by phase extension from 7.6 to 2.5 Å resolution with noncrystallographic symmetry to solve the structure of a bacteriophage capsid protein
    Nicola G A Abrescia
    Structural Biology Unit, CIC bioGUNE, CIBERehd, Bizkaia Technology Park, Derio, Spain
    Acta Crystallogr D Biol Crystallogr 67:228-32. 2011
  8. pmc Soaking of DNA into crystals of archaeal RNA polymerase achieved by desalting in droplets
    Magdalena N Wojtas
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Acta Crystallogr Sect F Struct Biol Cryst Commun 68:1134-8. 2012
  9. doi Three-dimensional visualization of forming Hepatitis C virus-like particles by electron-tomography
    Daniel Badia-Martinez
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Virology 430:120-6. 2012
  10. doi Archaeal transcription: making up for lost time
    Magdalena N Wojtas
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Biochem Soc Trans 41:356-61. 2013

Collaborators

Detail Information

Publications10

  1. pmc From lows to highs: using low-resolution models to phase X-ray data
    David I Stuart
    Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, England
    Acta Crystallogr D Biol Crystallogr 69:2257-65. 2013
    ..5 Å resolution, data from twinned crystals of the major coat protein (P2), ultimately yielding a quasi-atomic model of the particle, which provided significant insights into virus evolution and viral membrane biogenesis...
  2. pmc Structural and functional analyses of the interaction of archaeal RNA polymerase with DNA
    Magdalena N Wojtas
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Nucleic Acids Res 40:9941-52. 2012
    ..Our findings thus support Rpo13 as a RNAP-DNA stabilization factor, a role reminiscent of eukaryotic general transcriptional factors. The data further yield insight into the mechanisms and evolution of RNAP-DNA interaction...
  3. ncbi Structure unifies the viral universe
    Nicola G A Abrescia
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Annu Rev Biochem 81:795-822. 2012
    ..We also reflect on the future opportunities for a more concerted effort to provide high-throughput methods to facilitate the large-scale sampling of the virosphere...
  4. ncbi Combined approaches to study virus structures
    Daniel Badia-Martinez
    Structural Biology Unit, CICbioGUNE, CIBERehd, Bizkaia Technology Park, 48160, Derio, Spain
    Subcell Biochem 68:203-46. 2013
    ..The power of these hybrid method approaches are revealed through the various examples provided...
  5. pmc Mechanism of membranous tunnelling nanotube formation in viral genome delivery
    Bibiana Peralta
    Structural Biology Unit, CIC bioGUNE, CIBERehd, Derio, Spain
    PLoS Biol 11:e1001667. 2013
    ....
  6. doi Archaeal RNA polymerase: the influence of the protruding stalk in crystal packing and preliminary biophysical analysis of the Rpo13 subunit
    Magdalena Wojtas
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Biochem Soc Trans 39:25-30. 2011
    ....
  7. doi The use of low-resolution phasing followed by phase extension from 7.6 to 2.5 Å resolution with noncrystallographic symmetry to solve the structure of a bacteriophage capsid protein
    Nicola G A Abrescia
    Structural Biology Unit, CIC bioGUNE, CIBERehd, Bizkaia Technology Park, Derio, Spain
    Acta Crystallogr D Biol Crystallogr 67:228-32. 2011
    ..This represents an atypical example of an oligomeric protein for which the structure has been determined at high resolution by bootstrapping from low-resolution initial phases...
  8. pmc Soaking of DNA into crystals of archaeal RNA polymerase achieved by desalting in droplets
    Magdalena N Wojtas
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Acta Crystallogr Sect F Struct Biol Cryst Commun 68:1134-8. 2012
    ..Of the various crystals screened, one diffracted to 4.3 Å resolution and structural analysis showed the presence of bound DNA [Wojtas et al. (2012). Nucleic Acids Res. 40, doi:10.1093/nar/gks692]...
  9. doi Three-dimensional visualization of forming Hepatitis C virus-like particles by electron-tomography
    Daniel Badia-Martinez
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Virology 430:120-6. 2012
    ..This latter phenomenon could play an important role during the assembly of wt-HCV and explain the size-heterogeneity of its particles...
  10. doi Archaeal transcription: making up for lost time
    Magdalena N Wojtas
    Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain
    Biochem Soc Trans 41:356-61. 2013
    ..In the present review, we discuss the recent findings on the aRNAP and focus on the mechanisms by which the RNAP stabilizes the bound DNA during transcription...