Tim Sparwasser

Summary

Publications

  1. Mayer C, Tian L, Hesse C, Kühl A, Swallow M, Kruse F, et al. Anti-CD4 treatment inhibits autoimmunity in scurfy mice through the attenuation of co-stimulatory signals. J Autoimmun. 2014;50:23-32 pubmed publisher
    ..Particularly, CD4 blockade might represent a novel therapeutic option for the human IPEX syndrome. ..
  2. Puttur F, Francozo M, Solmaz G, Bueno C, Lindenberg M, Gohmert M, et al. Conventional Dendritic Cells Confer Protection against Mouse Cytomegalovirus Infection via TLR9 and MyD88 Signaling. Cell Rep. 2016;17:1113-1127 pubmed publisher
    ..Overall, we compartmentalize the cellular contribution of TLR9 and MyD88 signaling in individual DC subsets and evaluate the mechanism by which cDCs control MCMV immunity. ..
  3. Almeida L, Lochner M, Berod L, Sparwasser T. Metabolic pathways in T cell activation and lineage differentiation. Semin Immunol. 2016;28:514-524 pubmed publisher
    ..Moreover, we discuss how molecular regulators such as mTOR or AMPK link environmental changes to adaptations in the cellular metabolism and elucidate the consequences on T cell differentiation and function. ..