H J Zar

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. ncbi request reprint Respiratory infections in children in developing countries
    Heather J Zar
    Department of Paediatrics and Child Health, Division of Paediatric Pulmonology, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Pediatr Ann 31:133-8. 2002
  2. ncbi request reprint Childhood pneumonia--progress and challenges
    Heather J Zar
    School of Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children s Hospital, Rondebosch, Cape Town, South Africa
    S Afr Med J 96:890-900. 2006
  3. ncbi request reprint Diagnosis and management of community-acquired pneumonia in childhood--South African Thoracic Society Guidelines
    H J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital and University of Cape Town
    S Afr Med J 95:977-81, 984-90. 2005
  4. ncbi request reprint The changing prevalence of asthma, allergic rhinitis and atopic eczema in African adolescents from 1995 to 2002
    Heather J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Allergy Immunol 18:560-5. 2007
  5. pmc Effect of isoniazid prophylaxis on mortality and incidence of tuberculosis in children with HIV: randomised controlled trial
    Heather J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, South Africa
    BMJ 334:136. 2007
  6. ncbi request reprint Global paediatric pulmonology: out of Africa
    Heather J Zar
    Department of Paediatric Pulmonology, School of Child and Adolescent Health, Red Cross Childrens Hospital, University of Cape Town, South Africa
    Paediatr Respir Rev 7:S226-8. 2006
  7. pmc Randomised controlled trial of the efficacy of a metered dose inhaler with bottle spacer for bronchodilator treatment in acute lower airway obstruction
    H J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 92:142-6. 2007
  8. ncbi request reprint Oral trimethoprim-sulphamethoxazole levels in stable HIV-infected children
    Heather J Zar
    School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, Cape Town
    S Afr Med J 96:627-9. 2006
  9. doi request reprint Guideline for the management of acute asthma in children: 2013 update
    S Kling
    Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Children s Hospital, Parow, Cape Town, South Africa
    S Afr Med J 103:199-207. 2013
  10. pmc Sputum induction for the diagnosis of pulmonary tuberculosis in infants and young children in an urban setting in South Africa
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Arch Dis Child 82:305-8. 2000

Detail Information

Publications66

  1. ncbi request reprint Respiratory infections in children in developing countries
    Heather J Zar
    Department of Paediatrics and Child Health, Division of Paediatric Pulmonology, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Pediatr Ann 31:133-8. 2002
  2. ncbi request reprint Childhood pneumonia--progress and challenges
    Heather J Zar
    School of Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children s Hospital, Rondebosch, Cape Town, South Africa
    S Afr Med J 96:890-900. 2006
    ..This article reviews changes in the epidemiology, management and prevention of childhood pneumonia in developing countries, specifically in Africa and South Africa, and addresses future challenges...
  3. ncbi request reprint Diagnosis and management of community-acquired pneumonia in childhood--South African Thoracic Society Guidelines
    H J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital and University of Cape Town
    S Afr Med J 95:977-81, 984-90. 2005
    ..The incidence, severity and spectrum of childhood pneumonia have changed owing to the HIV epidemic. Increasing emergence of antimicrobial resistance necessitates a rational approach to the use of antibiotics in pneumonia management...
  4. ncbi request reprint The changing prevalence of asthma, allergic rhinitis and atopic eczema in African adolescents from 1995 to 2002
    Heather J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Allergy Immunol 18:560-5. 2007
    ..Symptoms of asthma, allergic rhinitis and atopic eczema in adolescents have increased over the past 7 yr in this geographical area. Allergic diseases are common in this group of adolescents and increasingly impair their quality of life...
  5. pmc Effect of isoniazid prophylaxis on mortality and incidence of tuberculosis in children with HIV: randomised controlled trial
    Heather J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, South Africa
    BMJ 334:136. 2007
    ..To investigate the impact of isoniazid prophylaxis on mortality and incidence of tuberculosis in children with HIV...
  6. ncbi request reprint Global paediatric pulmonology: out of Africa
    Heather J Zar
    Department of Paediatric Pulmonology, School of Child and Adolescent Health, Red Cross Childrens Hospital, University of Cape Town, South Africa
    Paediatr Respir Rev 7:S226-8. 2006
    ..Greater access to newer vaccines and, in HIV-infected children, to anti-retroviral therapy and prophylaxis is necessary to further reduce the burden of childhood respiratory illness in Africa...
  7. pmc Randomised controlled trial of the efficacy of a metered dose inhaler with bottle spacer for bronchodilator treatment in acute lower airway obstruction
    H J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 92:142-6. 2007
    ..Conventional spacers are expensive or unavailable in developing countries, but there is little information on the efficacy of low-cost spacers in young children...
  8. ncbi request reprint Oral trimethoprim-sulphamethoxazole levels in stable HIV-infected children
    Heather J Zar
    School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, Cape Town
    S Afr Med J 96:627-9. 2006
    ..However, oral therapy is desirable as the intravenous route is costly, time-consuming, more difficult to administer and carries a risk of needlestick injury...
  9. doi request reprint Guideline for the management of acute asthma in children: 2013 update
    S Kling
    Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Children s Hospital, Parow, Cape Town, South Africa
    S Afr Med J 103:199-207. 2013
    ..Acute asthma exacerbations remain a common cause of hospitalisation and healthcare utilisation in South African children...
  10. pmc Sputum induction for the diagnosis of pulmonary tuberculosis in infants and young children in an urban setting in South Africa
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Arch Dis Child 82:305-8. 2000
    ..Bacteriological confirmation of pulmonary tuberculosis is difficult in infants and young children. In adults and older children, sputum induction has been successfully used; this technique has not been tested in younger children...
  11. ncbi request reprint Pneumocystis carinii pneumonia in South African children infected with human immunodeficiency virus
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Pediatr Infect Dis J 19:603-7. 2000
    ..There is little information on the incidence of PCP in HIV-infected children in Africa...
  12. doi request reprint Safety of long-term isoniazid preventive therapy in children with HIV: a comparison of two dosing schedules
    S M Le Roux
    Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 17:26-31. 2013
    ..Two paediatric hospitals in Cape Town, South Africa...
  13. doi request reprint Community-acquired pneumonia in HIV-infected children: a global perspective
    D M Gray
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Curr Opin Pulm Med 16:208-16. 2010
    ..Pneumonia is a leading cause of morbidity and death in HIV-infected children. The aim of this study was to review recent advances in the epidemiology, cause, management and prevention of pneumonia in HIV-infected children...
  14. ncbi request reprint Home-made spacers for bronchodilator therapy in children with acute asthma: a randomised trial
    H J Zar
    Department of Paediatrics and Child Health, University of Cape Town and Red Cross War Memorial Children s Hospital, South Africa
    Lancet 354:979-82. 1999
    ..We tested the efficacy of home-made spacers (500 mL plastic bottle, polystyrene cup) compared with a conventional spacer for delivery of a beta2 agonist via MDI for children with acute asthma...
  15. doi request reprint Management of community-acquired pneumonia in HIV-infected children
    Diane Gray
    G25 Paediatric HIV AIDS Service, Groote Schuur Hospital, Observatory, Cape Town, South Africa
    Expert Rev Anti Infect Ther 7:437-51. 2009
    ..Specific preventive interventions, including chemoprophylaxis for P. jiroveci pneumonia or for TB and early initiation of highly active antiretroviral therapy, may significantly reduce the burden of pneumonia in HIV-infected children...
  16. ncbi request reprint Prevention of HIV-associated respiratory illness in children in developing countries: potential benefits
    H J Zar
    School of Child and Adolescent Health, Red Cross Childrens Hospital, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 7:820-7. 2003
    ....
  17. ncbi request reprint Prevalence of dihydropteroate synthase mutants in HIV-infected South African children with Pneumocystis jiroveci pneumonia
    H J Zar
    School of Child and Adolescent Health, Red Cross Childrens Hospital, University of Cape Town, Rondebosch, South Africa
    Clin Infect Dis 39:1047-51. 2004
    ....
  18. doi request reprint The impact of isoniazid preventive therapy and antiretroviral therapy on tuberculosis in children infected with HIV in a high tuberculosis incidence setting
    L J Frigati
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, Klipfontein Road, Rondebosch 7700, South Africa
    Thorax 66:496-501. 2011
    ..Strategies to prevent TB in children include isoniazid preventive therapy (IPT) and antiretroviral therapy (ART). IPT and ART have been reported to reduce TB incidence in adults but there are few studies in children...
  19. ncbi request reprint Changes in fatal and near-fatal asthma in an urban area of South Africa from 1980-1997
    H J Zar
    Dept of Pediatrics and Child Health, University of Cape Town, South Africa
    Eur Respir J 18:33-7. 2001
    ..However, the relatively high asthma mortality rate in people of mixed race and the predominance of deaths outside health facilities and on weekends suggest problems with access to care...
  20. doi request reprint Radiographic features of paediatric pneumocystis pneumonia -- a historical perspective
    R D Pitcher
    Division of Paediatric Radiology, Red Cross War Memorial Children s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Clin Radiol 63:666-72. 2008
    ..To establish differences in the radiographic features of PCP documented in HIV-infected children in developed and developing countries...
  21. ncbi request reprint Finger clubbing in children with human immunodeficiency virus infection
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Ann Trop Paediatr 21:15-9. 2001
    ..7% vs 24.2%, p = 0.035). In geographical areas with high HIV seroprevalence rates, the presence of clubbing in a child hospitalized for respiratory disease should raise the suspicion of HIV infection...
  22. doi request reprint Bilateral partial lung lavage in an infant with pulmonary alveolar proteinosis
    O Hodges
    Department of Anaesthesia, Groote Schuur Hospital, Observatory, South Africa
    Br J Anaesth 104:228-30. 2010
    ..The infant did not require extra-corporeal oxygenation during the procedure or postoperative ventilation. This method may offer a feasible option for performing lavage in a resource constrained environment...
  23. ncbi request reprint Guideline for the management of chronic asthma in children - 2009 update
    Cassim Motala
    University of Cape Town
    S Afr Med J 99:897-912. 2009
    ..The guideline document was endorsed by the South African Thoracic Society (SATS), the National Asthma Education Programme (NAEP), the South African Paediatric Association (SAPA) and the South African Academy of Family Practice...
  24. ncbi request reprint Aetiology and outcome of pneumonia in human immunodeficiency virus-infected children hospitalized in South Africa
    H J Zar
    Department of Paediatrics, University of Cape Town South Africa
    Acta Paediatr 90:119-25. 2001
    ..HIV-infected children with pneumonia have a worse outcome than HIV-negative patients...
  25. ncbi request reprint Child lung health: a global concern. An introduction to the series
    Heather J Zar
    School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Pediatr Pulmonol 42:1085-6. 2007
  26. doi request reprint Diagnosis of pulmonary tuberculosis in children: new advances
    Heather J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Expert Rev Anti Infect Ther 8:277-88. 2010
    ..Greater efforts to obtain a microbiologic diagnosis should be made in children, even in primary care settings. Further research to develop a more accurate, cost-effective and simple diagnostic test for childhood TB is urgently needed...
  27. ncbi request reprint Diagnosis of pulmonary tuberculosis in children--what's new?
    Heather J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital and University of Cape Town
    S Afr Med J 97:983-5. 2007
  28. doi request reprint Pneumocystis pneumonia in South African children with and without human immunodeficiency virus infection in the era of highly active antiretroviral therapy
    Brenda M Morrow
    Department of Paediatics and Child Health, University of Cape Town, Cape Town, South Africa
    Pediatr Infect Dis J 29:535-9. 2010
    ..Pneumocystis pneumonia (PCP) is a major cause of hospitalization and mortality in human immunodeficiency virus (HIV)-infected African children...
  29. ncbi request reprint Chronic lung disease in human immunodeficiency virus (HIV) infected children
    Heather J Zar
    School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Pediatr Pulmonol 43:1-10. 2008
    ..Preventative strategies include immunization, chemoprophylaxis, and micronutrient supplementation. Early use of HAART may prevent the development of chronic lung disease...
  30. doi request reprint Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay
    Mary Ann Davies
    Red Cross Children s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    AIDS 23:961-9. 2009
    ..To evaluate an enzyme-linked immunospot assay (ELISPOT) for the diagnosis of tuberculosis (TB) in HIV-infected children with suspected TB and to compare the performance of ELISPOT with the tuberculin skin test (TST)...
  31. pmc Human rhinovirus infection in young African children with acute wheezing
    Heidi E Smuts
    Division Medical Virology NHLS, Department of Clinical Laboratory Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 11:65. 2011
    ..The aim of this study was to determine the role of HRV as a cause of acute wheezing in South African children...
  32. doi request reprint Role of human metapneumovirus, human coronavirus NL63 and human bocavirus in infants and young children with acute wheezing
    Heidi Smuts
    Division Medical Virology NHLS, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Med Virol 80:906-12. 2008
    ..Viruses are an important cause of wheezing in preschool children; hMPV, HCoV NL63, and HBoV are less common than the usual respiratory pathogens...
  33. doi request reprint Improvements in lung function of a pediatric cystic fibrosis population in a developing country
    Brenda M Morrow
    School of Child and Adolescent Health, University of Cape Town UCT, Cape Town, WC, South Africa
    J Pediatr (Rio J) 84:403-9. 2008
    ..To document the change in pulmonary function of a pediatric cystic fibrosis population managed at the Red Cross War Memorial Children's Hospital, Cape Town, South Africa, between January 1999 and December 2006...
  34. ncbi request reprint Pneumococcal conjugate vaccine--a health priority
    Heather J Zar
    Department of Paediatric Pulmonology and School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital and University of Cape Town
    S Afr Med J 98:463-7. 2008
    ..Widespread availability and vaccination with PCV is urgently needed for all children under 2 years of age in South Africa. In addition, the use of PCV for all HIV-infected children under 9 years should be prioritised...
  35. ncbi request reprint Nosocomial pneumonia in pediatric patients: practical problems and rational solutions
    Heather J Zar
    Department of Paediatrics and Child Health, Faculty of Health Sciences, University of Cape Town, 46 Sawkins Road, Cape Town, South Africa
    Paediatr Drugs 4:73-83. 2002
    ..Of these, hand hygiene, appropriate infection control policies, and judicious use of antibacterials are essential...
  36. ncbi request reprint The impact of HIV infection and trimethoprim-sulphamethoxazole prophylaxis on bacterial isolates from children with community-acquired pneumonia in South Africa
    Heather J Zar
    School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    J Trop Pediatr 49:78-83. 2003
    ..17 of 79 (22 per cent), p = 0.009]. The rising prevalence of HIV infection and the use of TMP-SMX prophylaxis may alter the spectrum of colonizing and pathogenic bacteria in children in developing countries...
  37. ncbi request reprint A 500-ml plastic bottle: an effective spacer for children with asthma
    Heather J Zar
    Department of Paediatrics and Child Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Allergy Immunol 13:217-22. 2002
    ..It is concluded that a modified 500-ml plastic bottle is an effective spacer; modification and use of this device should be incorporated into international guidelines for the management of children with asthma...
  38. ncbi request reprint Global burden of pediatric respiratory illness and the implications for management and prevention
    Heather J Zar
    School Child and Adolescent Health, Red Cross War Memorial Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Pulmonol 36:457-61. 2003
  39. doi request reprint A randomized controlled trial of intermittent compared with daily cotrimoxazole preventive therapy in HIV-infected children
    Heather J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    AIDS 24:2225-32. 2010
    ..We investigated the efficacy and tolerability of intermittent CPT compared with daily CPT in HIV-infected children over a 5-year period...
  40. ncbi request reprint Tuberculosis in the developing world
    Heather J Zar
    Department of School Adolescent and Child Health, Red Cross Children s Hospital, University of Cape Town, 5th Floor, ICH Building, Klipfontein Road, Cape Town, South Africa
    Pediatr Pulmonol Suppl 26:53-4. 2004
  41. ncbi request reprint Etiology of sickle cell chest
    Heather J Zar
    Department of School Adolescent and Child Health, Red Cross Childrens Hospital, University of Cape Town, 7th floor ICH Building, Klipfontein Road, Cape Town 7700, South Africa
    Pediatr Pulmonol Suppl 26:188-90. 2004
  42. ncbi request reprint Pneumonia in HIV-infected and HIV-uninfected children in developing countries: epidemiology, clinical features, and management
    Heather J Zar
    School of Child and Adolescent Health, Department of Pediatric Pulmonology, Red Cross War Memorial Children s Hospital, University of Cape Town, Cape Town, South Africa
    Curr Opin Pulm Med 10:176-82. 2004
    ..This article reviews recent findings on the epidemiology, clinical features, and management of HIV-infected and -uninfected children with pneumonia in developing countries...
  43. ncbi request reprint Neonatal chlamydial infections: prevention and treatment
    Heather J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Paediatr Drugs 7:103-10. 2005
    ....
  44. ncbi request reprint Incorrect use of a homemade spacer for treatment of recurrent wheezing in children--a cause for concern
    Heather J Zar
    Red Cross Children s Hospital, University of Cape Town
    S Afr Med J 95:388, 390. 2005
  45. ncbi request reprint Clinical indicators of Pneumocystis jiroveci pneumonia (PCP) in South African children infected with the human immunodeficiency virus
    Geoffrey L Fatti
    Department of Human Biology, and Lung Institute, University of Cape Town, Cape Town, South Africa
    Int J Infect Dis 10:282-5. 2006
    ..Pneumocystis pneumonia (PCP) caused by Pneumocystis jiroveci is common in HIV-infected children, producing substantial morbidity and mortality. Initiation of timely, effective therapy depends on clinical identification of children with PCP...
  46. ncbi request reprint Induced sputum versus gastric lavage for microbiological confirmation of pulmonary tuberculosis in infants and young children: a prospective study
    Heather J Zar
    School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Lancet 365:130-4. 2005
    ..We aimed to compare the yield of Mycobacterium tuberculosis from repeated induced sputum with that from gastric lavage in young children from an area with a high rate of HIV and tuberculosis...
  47. ncbi request reprint Serum immunoglobulin E levels in human immunodeficiency virus-infected children with pneumonia
    Heather J Zar
    Department of Paediatrics and Child Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Allergy Immunol 13:328-33. 2002
    ..HIV-infected children with pneumonia have higher serum IgE compared with seronegative patients. In HIV-positive children, IgE levels did not correlate with the degree of immunosuppression or with outcome...
  48. doi request reprint Isoniazid preventive therapy in HIV-infected children on antiretroviral therapy: a pilot study
    D M Gray
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 18:322-7. 2014
    ..Data on isoniazid preventive therapy (IPT) efficacy in HIV-infected children receiving antiretroviral therapy (ART) are inconclusive...
  49. doi request reprint Pneumonia in low and middle income countries: progress and challenges
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Childrens Hospital, University of Cape Town, Cape Town, South Africa
    Thorax 68:1052-6. 2013
    ..Widespread implementation of currently effective preventative and management strategies for pneumonia remains challenging in many low and middle income countries. ..
  50. doi request reprint Chest radiographic features of lymphocytic interstitial pneumonitis in HIV-infected children
    R D Pitcher
    Division of Paediatric Radiology, Red Cross War Memorial Children s Hospital, Department of Radiation Medicine, University of Cape Town, South Africa
    Clin Radiol 65:150-4. 2010
    ....
  51. doi request reprint Induced sputum or gastric lavage for community-based diagnosis of childhood pulmonary tuberculosis?
    M Hatherill
    South African Tuberculosis Vaccine Initiative SATVI, Institute of Infectious Disease and Molecular Medicine IIDMM, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 94:195-201. 2009
    ..To compare the diagnostic yield of Mycobacterium tuberculosis from induced sputum (IS) and gastric lavage (GL) among children in a community setting...
  52. ncbi request reprint Guideline for the management of chronic asthma in children--2009 update
    C Motala
    Division of Allergy, Department of Paediatrics and Child Health, University of Cape Town and Red Cross War Memorial Children s Hospital, Cape Town
    S Afr Med J 99:898-912. 2009
    ..The main aim of the guideline is to promote a better standard of treatment based on understanding of the pathophysiology and pharmacotherapy of asthma, and encouraging uniformity in asthma management...
  53. ncbi request reprint Sputum induction as a diagnostic tool for community-acquired pneumonia in infants and young children from a high HIV prevalence area
    H J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, South Africa
    Pediatr Pulmonol 36:58-62. 2003
    ..In conclusion, induced sputum is a useful and safe diagnostic procedure in infants and children with CAP from a high HIV prevalence area...
  54. pmc Lung deposition of aerosol--a comparison of different spacers
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 82:495-8. 2000
    ....
  55. pmc Adherence to isoniazid prophylaxis among HIV-infected children: a randomized controlled trial comparing two dosing schedules
    Stanzi M le Roux
    School of Child and Adolescent Health, University of Cape Town, South Africa
    BMC Med 7:67. 2009
    ..We investigated adherence to isoniazid prophylaxis administered daily, compared to three times a week, and predictors of adherence amongst HIV-infected children...
  56. doi request reprint Sputum induction for microbiological diagnosis of childhood pulmonary tuberculosis in a community setting
    H A Moore
    Kuyasa Clinic, Khayelitsha, Cape Town, South Africa
    Int J Tuberc Lung Dis 15:1185-90, i. 2011
    ..Sputum induction has increasingly enabled microbiological confirmation of pulmonary tuberculosis (PTB) in hospitalised children, but it has not been evaluated in a community setting...
  57. pmc Diagnostic accuracy of chest radiography in detecting mediastinal lymphadenopathy in suspected pulmonary tuberculosis
    G H Swingler
    Division of Paediatric Medicine, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 90:1153-6. 2005
    ..To estimate the diagnostic accuracy of chest radiography in the detection of chest lymphadenopathy in children with clinically suspected pulmonary tuberculosis...
  58. pmc Reversion and conversion of Mycobacterium tuberculosis IFN-gamma ELISpot results during anti-tuberculous treatment in HIV-infected children
    Tom G Connell
    Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 10:138. 2010
    ..The kinetics of IFN-gamma responses to Mycobacterium tuberculosis (MTB) antigens in HIV-infected children during treatment have not however been previously investigated...
  59. doi request reprint Guideline for the management of acute asthma in children: 2013 update
    S Kling
    Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Children s Hospital, Parow, Cape Town, South Africa
    S Afr Med J 103:199-207. 2013
    ....
  60. ncbi request reprint Chlamydia trachomatis lower respiratory tract infection in infants
    H J Zar
    Department of Paediatrics and Child Health, University of Cape Town, South Africa
    Ann Trop Paediatr 19:9-13. 1999
    ..pneumoniae, S. aureus and N. gonorrhoeae were cultured from five different patients infected with chlamydia. The majority of infants with chlamydial infection had mild disease requiring only outpatient anti- biotic therapy...
  61. doi request reprint Global strategy for asthma management and prevention: GINA executive summary
    E D Bateman
    University of Cape Town Lung Institute, PO Box 34560, Groote School, 7700 Mowbray, Cape Town, South Africa
    Eur Respir J 31:143-78. 2008
    ..The importance of the patient-care giver partnership and guided self-management, along with setting goals for treatment, are also emphasised...
  62. ncbi request reprint Failure of chemoprophylaxis with standard antituberculosis agents in child contacts of multidrug-resistant tuberculosis cases
    Darryl B Sneag
    Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, USA
    Pediatr Infect Dis J 26:1142-6. 2007
    ..Current guidelines of World Health Organization suggest that isoniazid (INH), the standard first-line chemoprophylaxis, be used for those exposed to MDR-TB...
  63. ncbi request reprint Co-trimoxazole prophylaxis in African children with HIV-1
    Shabir A Madhi
    Lancet 365:749-50; author reply 750-1. 2005
  64. ncbi request reprint Training pediatric pulmonologists for the future: academic is a state of mind not just a location
    Robert B Mellins
    Pediatric Pulmonary Division, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Pediatr Pulmonol Suppl 26:9-11. 2004
  65. pmc High incidence of antimicrobial resistant organisms including extended spectrum beta-lactamase producing Enterobacteriaceae and methicillin-resistant Staphylococcus aureus in nasopharyngeal and blood isolates of HIV-infected children from Cape Town, South
    Mark F Cotton
    Department of Paediatrics, Faculty of Health Sciences, Stellenbosch University, Cape Town South Africa
    BMC Infect Dis 8:40. 2008
    ....
  66. ncbi request reprint Sensitivity and specificity of nested and real-time PCR for the detection of Pneumocystis jiroveci in clinical specimens
    Miriam J Alvarez-Martinez
    Microbiology Department, Hospital Clinic IDIBAPS, Universitat de Barcelona, Barcelona 08036, Spain
    Diagn Microbiol Infect Dis 56:153-60. 2006
    ..Real-time PCR has a statistically significantly better specificity than nested PCR (P = .015) and is likely to generate fewer false positives...