H J Zar

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. ncbi Home-made spacers for bronchodilator therapy in children with acute asthma: a randomised trial
    H J Zar
    Department of Paediatrics and Child Health, University of Cape Town and Red Cross War Memorial Children s Hospital, South Africa
    Lancet 354:979-82. 1999
  2. ncbi Serum immunoglobulin E levels in human immunodeficiency virus-infected children with pneumonia
    Heather J Zar
    Department of Paediatrics and Child Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Allergy Immunol 13:328-33. 2002
  3. ncbi A 500-ml plastic bottle: an effective spacer for children with asthma
    Heather J Zar
    Department of Paediatrics and Child Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Allergy Immunol 13:217-22. 2002
  4. ncbi Nosocomial pneumonia in pediatric patients: practical problems and rational solutions
    Heather J Zar
    Department of Paediatrics and Child Health, Faculty of Health Sciences, University of Cape Town, 46 Sawkins Road, Cape Town, South Africa
    Paediatr Drugs 4:73-83. 2002
  5. ncbi Finger clubbing in children with human immunodeficiency virus infection
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Ann Trop Paediatr 21:15-9. 2001
  6. ncbi Aetiology and outcome of pneumonia in human immunodeficiency virus-infected children hospitalized in South Africa
    H J Zar
    Department of Paediatrics, University of Cape Town South Africa
    Acta Paediatr 90:119-25. 2001
  7. ncbi Pneumocystis carinii pneumonia in South African children infected with human immunodeficiency virus
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Pediatr Infect Dis J 19:603-7. 2000
  8. pmc Lung deposition of aerosol--a comparison of different spacers
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 82:495-8. 2000
  9. pmc Sputum induction for the diagnosis of pulmonary tuberculosis in infants and young children in an urban setting in South Africa
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Arch Dis Child 82:305-8. 2000
  10. ncbi The impact of HIV infection and trimethoprim-sulphamethoxazole prophylaxis on bacterial isolates from children with community-acquired pneumonia in South Africa
    Heather J Zar
    School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    J Trop Pediatr 49:78-83. 2003

Detail Information

Publications35

  1. ncbi Home-made spacers for bronchodilator therapy in children with acute asthma: a randomised trial
    H J Zar
    Department of Paediatrics and Child Health, University of Cape Town and Red Cross War Memorial Children s Hospital, South Africa
    Lancet 354:979-82. 1999
    ..We tested the efficacy of home-made spacers (500 mL plastic bottle, polystyrene cup) compared with a conventional spacer for delivery of a beta2 agonist via MDI for children with acute asthma...
  2. ncbi Serum immunoglobulin E levels in human immunodeficiency virus-infected children with pneumonia
    Heather J Zar
    Department of Paediatrics and Child Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Allergy Immunol 13:328-33. 2002
    ..HIV-infected children with pneumonia have higher serum IgE compared with seronegative patients. In HIV-positive children, IgE levels did not correlate with the degree of immunosuppression or with outcome...
  3. ncbi A 500-ml plastic bottle: an effective spacer for children with asthma
    Heather J Zar
    Department of Paediatrics and Child Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Pediatr Allergy Immunol 13:217-22. 2002
    ..It is concluded that a modified 500-ml plastic bottle is an effective spacer; modification and use of this device should be incorporated into international guidelines for the management of children with asthma...
  4. ncbi Nosocomial pneumonia in pediatric patients: practical problems and rational solutions
    Heather J Zar
    Department of Paediatrics and Child Health, Faculty of Health Sciences, University of Cape Town, 46 Sawkins Road, Cape Town, South Africa
    Paediatr Drugs 4:73-83. 2002
    ..Of these, hand hygiene, appropriate infection control policies, and judicious use of antibacterials are essential...
  5. ncbi Finger clubbing in children with human immunodeficiency virus infection
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Ann Trop Paediatr 21:15-9. 2001
    ..7% vs 24.2%, p = 0.035). In geographical areas with high HIV seroprevalence rates, the presence of clubbing in a child hospitalized for respiratory disease should raise the suspicion of HIV infection...
  6. ncbi Aetiology and outcome of pneumonia in human immunodeficiency virus-infected children hospitalized in South Africa
    H J Zar
    Department of Paediatrics, University of Cape Town South Africa
    Acta Paediatr 90:119-25. 2001
    ..HIV-infected children with pneumonia have a worse outcome than HIV-negative patients...
  7. ncbi Pneumocystis carinii pneumonia in South African children infected with human immunodeficiency virus
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Pediatr Infect Dis J 19:603-7. 2000
    ..There is little information on the incidence of PCP in HIV-infected children in Africa...
  8. pmc Lung deposition of aerosol--a comparison of different spacers
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 82:495-8. 2000
    ....
  9. pmc Sputum induction for the diagnosis of pulmonary tuberculosis in infants and young children in an urban setting in South Africa
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Arch Dis Child 82:305-8. 2000
    ..Bacteriological confirmation of pulmonary tuberculosis is difficult in infants and young children. In adults and older children, sputum induction has been successfully used; this technique has not been tested in younger children...
  10. ncbi The impact of HIV infection and trimethoprim-sulphamethoxazole prophylaxis on bacterial isolates from children with community-acquired pneumonia in South Africa
    Heather J Zar
    School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    J Trop Pediatr 49:78-83. 2003
    ..17 of 79 (22 per cent), p = 0.009]. The rising prevalence of HIV infection and the use of TMP-SMX prophylaxis may alter the spectrum of colonizing and pathogenic bacteria in children in developing countries...
  11. doi Guideline for the management of acute asthma in children: 2013 update
    S Kling
    Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Children s Hospital, Parow, Cape Town, South Africa
    S Afr Med J 103:199-207. 2013
    ..Acute asthma exacerbations remain a common cause of hospitalisation and healthcare utilisation in South African children...
  12. ncbi Sputum induction as a diagnostic tool for community-acquired pneumonia in infants and young children from a high HIV prevalence area
    H J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, South Africa
    Pediatr Pulmonol 36:58-62. 2003
    ..In conclusion, induced sputum is a useful and safe diagnostic procedure in infants and children with CAP from a high HIV prevalence area...
  13. doi Safety of long-term isoniazid preventive therapy in children with HIV: a comparison of two dosing schedules
    S M Le Roux
    Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 17:26-31. 2013
    ..Two paediatric hospitals in Cape Town, South Africa...
  14. doi Community-acquired pneumonia in HIV-infected children: a global perspective
    D M Gray
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
    Curr Opin Pulm Med 16:208-16. 2010
    ..Pneumonia is a leading cause of morbidity and death in HIV-infected children. The aim of this study was to review recent advances in the epidemiology, cause, management and prevention of pneumonia in HIV-infected children...
  15. pmc Randomised controlled trial of the efficacy of a metered dose inhaler with bottle spacer for bronchodilator treatment in acute lower airway obstruction
    H J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 92:142-6. 2007
    ..Conventional spacers are expensive or unavailable in developing countries, but there is little information on the efficacy of low-cost spacers in young children...
  16. doi Induced sputum or gastric lavage for community-based diagnosis of childhood pulmonary tuberculosis?
    M Hatherill
    South African Tuberculosis Vaccine Initiative SATVI, Institute of Infectious Disease and Molecular Medicine IIDMM, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 94:195-201. 2009
    ..To compare the diagnostic yield of Mycobacterium tuberculosis from induced sputum (IS) and gastric lavage (GL) among children in a community setting...
  17. ncbi Prevalence of dihydropteroate synthase mutants in HIV-infected South African children with Pneumocystis jiroveci pneumonia
    H J Zar
    School of Child and Adolescent Health, Red Cross Childrens Hospital, University of Cape Town, Rondebosch, South Africa
    Clin Infect Dis 39:1047-51. 2004
    ....
  18. ncbi Asthma--is survival good enough?
    R J Green
    Department of Paediatrics and Child Health, University of Pretoria, South Africa
    S Afr Med J 97:172-4. 2007
  19. doi The impact of isoniazid preventive therapy and antiretroviral therapy on tuberculosis in children infected with HIV in a high tuberculosis incidence setting
    L J Frigati
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, Klipfontein Road, Rondebosch 7700, South Africa
    Thorax 66:496-501. 2011
    ..Strategies to prevent TB in children include isoniazid preventive therapy (IPT) and antiretroviral therapy (ART). IPT and ART have been reported to reduce TB incidence in adults but there are few studies in children...
  20. ncbi Guideline for the management of chronic asthma in children--2009 update
    C Motala
    Division of Allergy, Department of Paediatrics and Child Health, University of Cape Town and Red Cross War Memorial Children s Hospital, Cape Town
    S Afr Med J 99:898-912. 2009
    ..The main aim of the guideline is to promote a better standard of treatment based on understanding of the pathophysiology and pharmacotherapy of asthma, and encouraging uniformity in asthma management...
  21. doi Radiographic features of paediatric pneumocystis pneumonia -- a historical perspective
    R D Pitcher
    Division of Paediatric Radiology, Red Cross War Memorial Children s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Clin Radiol 63:666-72. 2008
    ..To establish differences in the radiographic features of PCP documented in HIV-infected children in developed and developing countries...
  22. ncbi Changes in fatal and near-fatal asthma in an urban area of South Africa from 1980-1997
    H J Zar
    Dept of Pediatrics and Child Health, University of Cape Town, South Africa
    Eur Respir J 18:33-7. 2001
    ..However, the relatively high asthma mortality rate in people of mixed race and the predominance of deaths outside health facilities and on weekends suggest problems with access to care...
  23. ncbi Diagnosis and management of community-acquired pneumonia in childhood--South African Thoracic Society Guidelines
    H J Zar
    School of Child and Adolescent Health, Red Cross Children s Hospital and University of Cape Town
    S Afr Med J 95:977-81, 984-90. 2005
    ..The incidence, severity and spectrum of childhood pneumonia have changed owing to the HIV epidemic. Increasing emergence of antimicrobial resistance necessitates a rational approach to the use of antibiotics in pneumonia management...
  24. doi Bilateral partial lung lavage in an infant with pulmonary alveolar proteinosis
    O Hodges
    Department of Anaesthesia, Groote Schuur Hospital, Observatory, South Africa
    Br J Anaesth 104:228-30. 2010
    ..The infant did not require extra-corporeal oxygenation during the procedure or postoperative ventilation. This method may offer a feasible option for performing lavage in a resource constrained environment...
  25. ncbi Guideline for the management of chronic asthma in children - 2009 update
    Cassim Motala
    University of Cape Town
    S Afr Med J 99:897-912. 2009
    ..The guideline document was endorsed by the South African Thoracic Society (SATS), the National Asthma Education Programme (NAEP), the South African Paediatric Association (SAPA) and the South African Academy of Family Practice...
  26. ncbi Isoniazid preventive therapy in HIV-infected children on antiretroviral therapy: a pilot study
    D M Gray
    Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 18:322-7. 2014
    ..Data on isoniazid preventive therapy (IPT) efficacy in HIV-infected children receiving antiretroviral therapy (ART) are inconclusive...
  27. ncbi Prevention of HIV-associated respiratory illness in children in developing countries: potential benefits
    H J Zar
    School of Child and Adolescent Health, Red Cross Childrens Hospital, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 7:820-7. 2003
    ....
  28. doi Chest radiographic features of lymphocytic interstitial pneumonitis in HIV-infected children
    R D Pitcher
    Division of Paediatric Radiology, Red Cross War Memorial Children s Hospital, Department of Radiation Medicine, University of Cape Town, South Africa
    Clin Radiol 65:150-4. 2010
    ....
  29. pmc Pneumonia in low and middle income countries: progress and challenges
    H J Zar
    Department of Paediatrics and Child Health, Red Cross War Memorial Childrens Hospital, University of Cape Town, Cape Town, South Africa
    Thorax 68:1052-6. 2013
    ..Widespread implementation of currently effective preventative and management strategies for pneumonia remains challenging in many low and middle income countries. ..
  30. doi Sputum induction for microbiological diagnosis of childhood pulmonary tuberculosis in a community setting
    H A Moore
    Kuyasa Clinic, Khayelitsha, Cape Town, South Africa
    Int J Tuberc Lung Dis 15:1185-90, i. 2011
    ..Sputum induction has increasingly enabled microbiological confirmation of pulmonary tuberculosis (PTB) in hospitalised children, but it has not been evaluated in a community setting...
  31. doi Global strategy for asthma management and prevention: GINA executive summary
    E D Bateman
    University of Cape Town Lung Institute, PO Box 34560, Groote School, 7700 Mowbray, Cape Town, South Africa
    Eur Respir J 31:143-78. 2008
    ..The importance of the patient-care giver partnership and guided self-management, along with setting goals for treatment, are also emphasised...
  32. doi Guideline for the management of acute asthma in children: 2013 update
    S Kling
    Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Children s Hospital, Parow, Cape Town, South Africa
    S Afr Med J 103:199-207. 2013
    ....
  33. ncbi Chlamydia trachomatis lower respiratory tract infection in infants
    H J Zar
    Department of Paediatrics and Child Health, University of Cape Town, South Africa
    Ann Trop Paediatr 19:9-13. 1999
    ..pneumoniae, S. aureus and N. gonorrhoeae were cultured from five different patients infected with chlamydia. The majority of infants with chlamydial infection had mild disease requiring only outpatient anti- biotic therapy...
  34. pmc Diagnostic accuracy of chest radiography in detecting mediastinal lymphadenopathy in suspected pulmonary tuberculosis
    G H Swingler
    Division of Paediatric Medicine, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Arch Dis Child 90:1153-6. 2005
    ..To estimate the diagnostic accuracy of chest radiography in the detection of chest lymphadenopathy in children with clinically suspected pulmonary tuberculosis...
  35. ncbi Influenza guideline for South Africa--update 2008
    R J Green
    Department of Paediatrics and Child Health, University of Pretoria, Pretoria
    S Afr Med J 98:224-30. 2008
    ....