Robin Wood

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. pmc Lipoarabinomannan in urine during tuberculosis treatment: association with host and pathogen factors and mycobacteriuria
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town Faculty of Health Sciences, Cape Town, South Africa
    BMC Infect Dis 12:47. 2012
  2. pmc Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925, Cape Town, South Africa
    Syst Rev 2:6. 2013
  3. pmc Mean CD4 cell count changes in patients failing a first-line antiretroviral therapy in resource-limited settings
    Alexandra Calmy
    HIV Unit, Geneva University Hospital, Geneva, Switzerland
    BMC Infect Dis 12:147. 2012
  4. pmc The epidemiology and clinical correlates of HIV-1 co-receptor tropism in non-subtype B infections from India, Uganda and South Africa
    Quazi Ataher
    Pfizer Inc, New York, NY 10017, USA
    J Int AIDS Soc 15:2. 2012
  5. pmc Quality of life and the impact of drug toxicities in a South African community-based antiretroviral programme
    Jennifer Pitt
    Desmond Tutu HIV Foundation, Institute of Infectious Diseases and Molecular Medicine, Cape Town, South Africa
    J Int AIDS Soc 12:5. 2009
  6. pmc Asking the right questions: developing evidence-based strategies for treating HIV in women and children
    Quarraisha Abdool Karim
    Department of Epidemiology, Columbia University, New York, USA
    BMC Public Health 11:388. 2011
  7. pmc Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa: a cohort study
    Katherine L Fielding
    London School of Hygiene and Tropical Medicine, London, UK
    BMC Infect Dis 8:93. 2008
  8. pmc Plasma levels of soluble urokinase-type plasminogen activator receptor (suPAR) and early mortality risk among patients enrolling for antiretroviral treatment in South Africa
    Stephen D Lawn
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 7:41. 2007
  9. pmc Identification of losses to follow-up in a community-based antiretroviral therapy clinic in South Africa using a computerized pharmacy tracking system
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    BMC Infect Dis 10:329. 2010
  10. ncbi request reprint Should we be initiating antiretroviral therapy earlier? An argument in favour
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, and University of Cape Town, South Africa
    S Afr Med J 95:926, 928. 2005

Detail Information

Publications132 found, 100 shown here

  1. pmc Lipoarabinomannan in urine during tuberculosis treatment: association with host and pathogen factors and mycobacteriuria
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town Faculty of Health Sciences, Cape Town, South Africa
    BMC Infect Dis 12:47. 2012
    ..However, the LAM-ELISA assay has demonstrated variable sensitivity in diagnosing TB in diverse clinical populations. We therefore explored pathogen and host factors potentially impacting LAM detection...
  2. pmc Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925, Cape Town, South Africa
    Syst Rev 2:6. 2013
    ..We, therefore, propose to conduct a review of current best evidence for the use of mobile phone text messaging to promote patient adherence to TB treatment...
  3. pmc Mean CD4 cell count changes in patients failing a first-line antiretroviral therapy in resource-limited settings
    Alexandra Calmy
    HIV Unit, Geneva University Hospital, Geneva, Switzerland
    BMC Infect Dis 12:147. 2012
    ..We assessed the impact of on-going HIV-RNA replication on CD4 cell count slopes in patients treated with a first-line combination ART...
  4. pmc The epidemiology and clinical correlates of HIV-1 co-receptor tropism in non-subtype B infections from India, Uganda and South Africa
    Quazi Ataher
    Pfizer Inc, New York, NY 10017, USA
    J Int AIDS Soc 15:2. 2012
    ..This study was undertaken to evaluate HIV-1 co-receptor tropism in the developing world where non-B subtypes predominate, in order to assess the therapeutic and prophylactic potential of CCR5 antagonists in these regions...
  5. pmc Quality of life and the impact of drug toxicities in a South African community-based antiretroviral programme
    Jennifer Pitt
    Desmond Tutu HIV Foundation, Institute of Infectious Diseases and Molecular Medicine, Cape Town, South Africa
    J Int AIDS Soc 12:5. 2009
    ..abstract:..
  6. pmc Asking the right questions: developing evidence-based strategies for treating HIV in women and children
    Quarraisha Abdool Karim
    Department of Epidemiology, Columbia University, New York, USA
    BMC Public Health 11:388. 2011
    ..The guideline's new goals present an opportunity for advancing the women and children's agenda outlined in the Consensus Statement...
  7. pmc Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa: a cohort study
    Katherine L Fielding
    London School of Hygiene and Tropical Medicine, London, UK
    BMC Infect Dis 8:93. 2008
    ..Reasons for the variation in reported treatment outcomes from antiretroviral therapy (ART) programmes in developing countries are not clearly defined...
  8. pmc Plasma levels of soluble urokinase-type plasminogen activator receptor (suPAR) and early mortality risk among patients enrolling for antiretroviral treatment in South Africa
    Stephen D Lawn
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 7:41. 2007
    ..The practical utility of plasma suPAR in assessing short-term all-cause mortality risk was evaluated in patients with advanced immunodeficiency enrolling in an antiretroviral treatment (ART) programme in South Africa...
  9. pmc Identification of losses to follow-up in a community-based antiretroviral therapy clinic in South Africa using a computerized pharmacy tracking system
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    BMC Infect Dis 10:329. 2010
    ..We determined the duration of pharmacy delay that optimally identified true LTFU...
  10. ncbi request reprint Should we be initiating antiretroviral therapy earlier? An argument in favour
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, and University of Cape Town, South Africa
    S Afr Med J 95:926, 928. 2005
  11. pmc Tuberculosis transmission to young children in a South African community: modeling household and community infection risks
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Faculty of Health Sciences, Cape Town, South Africa
    Clin Infect Dis 51:401-8. 2010
    ..A model was used to explore the interactions between prevalence of adult tuberculosis infection, adult-to-child contacts, and household ventilation, which could result in such a high annual risk of tuberculosis infection...
  12. ncbi request reprint When to start antiretroviral therapy in children with TB?
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Expert Rev Anti Infect Ther 8:1101-4. 2010
    ..While results of adult randomized trials addressing this question are becoming available, there are little data to inform the 'when to start' question for children...
  13. pmc Atazanavir: its role in HIV treatment
    Robin Wood
    Institute of Infectious Disease and Molecular Medicine, University of Cape Town Faculty of Health Sciences, Anzio Road, Observatory 7925, South Africa
    Expert Rev Anti Infect Ther 6:785-96. 2008
    ..Atazanavir is licensed for once-daily use and atazanavir/ritonavir competes with lopinavir/ritonavir as the most commonly prescribed PI...
  14. ncbi request reprint The case for integrating tuberculosis and HIV treatment services in South Africa
    Robin Wood
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Infect Dis 196:S497-9. 2007
    ....
  15. ncbi request reprint Nevirapine toxicity--implications for management of South African patients
    Robin Wood
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town
    S Afr Med J 95:253-7. 2005
  16. pmc Accuracy of immunological criteria for identifying virological failure in children on antiretroviral therapy - the IeDEA Southern Africa Collaboration
    Mary Ann Davies
    School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    Trop Med Int Health 16:1367-71. 2011
    ....
  17. ncbi request reprint Conservation of first-line antiretroviral treatment regimen where therapeutic options are limited
    Catherine Orrell
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    Antivir Ther 12:83-8. 2007
    ....
  18. pmc Tuberculosis during the first year of antiretroviral therapy in a South African cohort using an intensive pretreatment screening strategy
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    AIDS 24:1323-8. 2010
    ....
  19. pmc Linkage to HIV, TB and non-communicable disease care from a mobile testing unit in Cape Town, South Africa
    Darshini Govindasamy
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    PLoS ONE 8:e80017. 2013
    ..HIV counseling and testing may serve as an entry point for non-communicable disease screening...
  20. pmc The role of targeted viral load testing in diagnosing virological failure in children on antiretroviral therapy with immunological failure
    Mary Ann Davies
    School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa Empilweni Service and Research Unit, Rahima Moosa Mother and Child Hospital and University of Witwatersrand, Johannesburg, South Africa Red Cross Children s Hospital and School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa Wits Reproductive Health and HIV Institute Harriet Shezi Children s Clinic, Chris Hani Baragwanath Hospital, Soweto, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa Tygerberg Academic Hospital, University of Stellenbosch, Stellenbosch, South Africa Médecins Sans Frontières South Africa and Khayelitsha ART Programme, Khayelitsha, Cape Town, South Africa Sinikithemba Clinic, McCord Hospital, Durban, South Africa Gugulethu Community Health Centre and Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa Institute of Social and Preventive Medicine ISPM, University of Bern, Bern, Switzerland
    Trop Med Int Health 17:1386-90. 2012
    ....
  21. pmc Antiretroviral program associated with reduction in untreated prevalent tuberculosis in a South African township
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Am J Respir Crit Care Med 182:1080-5. 2010
    ..Prevalent untreated TB is the main source of transmission. In settings with large burdens of human immunodeficiency virus (HIV) and TB, highly active antiretroviral therapy (HAART) may contribute to TB control...
  22. pmc Increasing transfers-out from an antiretroviral treatment service in South Africa: patient characteristics and rates of virological non-suppression
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    PLoS ONE 8:e57907. 2013
    ..To determine the proportion, characteristics and outcomes of patients who transfer-out from an antiretroviral therapy (ART) service in a South African township...
  23. pmc Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    PLoS Med 10:e1001418. 2013
    ..We aimed to estimate the life expectancy of patients starting ART in South Africa and compare it with that of HIV-negative adults...
  24. ncbi request reprint Tuberculosis-associated immune reconstitution disease: incidence, risk factors and impact in an antiretroviral treatment service in South Africa
    Stephen D Lawn
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa
    AIDS 21:335-41. 2007
    ..To determine the burden and impact of immune reconstitution disease (IRD) associated with tuberculosis (TB) among patients initiating antiretroviral treatment (ART) in sub-Saharan Africa...
  25. ncbi request reprint When to initiate highly active antiretroviral therapy in sub-Saharan Africa? A South African cost-effectiveness study
    Motasim Badri
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Department of Medicine, University of Cape Town, South Africa
    Antivir Ther 11:63-72. 2006
    ..However, cost-effectiveness of initiating treatment at different CD4 count thresholds has not been explored in resource-poor settings...
  26. pmc Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial
    Joseph N Jarvis
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Infectious Diseases Unit, GF Jooste Hospital, Cape Town, South Africa
    AIDS 26:1105-13. 2012
    ..We performed a randomized controlled trial to determine whether addition of IFNγ to standard therapy increased the rate of clearance of cryptococcal infection in HIV-associated cryptococcal meningitis...
  27. doi request reprint Comparison of the early fungicidal activity of high-dose fluconazole, voriconazole, and flucytosine as second-line drugs given in combination with amphotericin B for the treatment of HIV-associated cryptococcal meningitis
    Angela Loyse
    Infectious Diseases Unit, GF Jooste Hospital, Cape Town, South Africa
    Clin Infect Dis 54:121-8. 2012
    ..Alternative, more widely available, and/or more effective antifungal combination treatment regimens are urgently needed...
  28. pmc Utility of CD4 cell counts for early prediction of virological failure during antiretroviral therapy in a resource-limited setting
    Motasim Badri
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 8:89. 2008
    ..However, the practical utility of CD4 cell count measurements as an alternative monitoring strategy has not been rigorously assessed...
  29. ncbi request reprint Immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis: a prospective study
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    J Acquir Immune Defic Syndr 51:130-4. 2009
    ..Prospective data on incidence, characteristics, and risk factors for cryptococcal meningitis immune reconstitution inflammatory syndrome (CM-IRIS) are lacking...
  30. pmc Community perspectives on the ethical issues surrounding adolescent HIV vaccine trials in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa
    Vaccine 26:5679-83. 2008
    ..In general, ethical adolescent HIV vaccine trials will be feasible in this community...
  31. pmc Time to initiation of antiretroviral therapy among patients with HIV-associated tuberculosis in Cape Town, South Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 57:136-40. 2011
    ..7%, and 51.1% of patients started ART within 2, 4, and 8 weeks of tuberculosis treatment, respectively. Operational barriers must be tackled to permit further acceleration of ART initiation as recommended by 2010 WHO ART guidelines...
  32. pmc Utility of interferon-gamma ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    BMC Infect Dis 7:99. 2007
    ..We studied determinants of ELISPOT responses among patients with advanced HIV infection (but without active TB) living in a South African community with very high TB notification rates...
  33. ncbi request reprint Urine lipoarabinomannan assay for tuberculosis screening before antiretroviral therapy diagnostic yield and association with immune reconstitution disease
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa, and Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    AIDS 23:1875-80. 2009
    ..To assess the utility of urine lipoarabinomannan (LAM) detection as a diagnostic screening test for tuberculosis (TB) in HIV-infected patients with advanced immuno deficiency and high prevalence of sputum smear-negative pulmonary disease...
  34. pmc Temporal association between incident tuberculosis and poor virological outcomes in a South African antiretroviral treatment service
    Ankur Gupta-Wright
    Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom and The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 64:261-70. 2013
    ..The temporal relationship between incident tuberculosis (TB) and virological outcomes during antiretroviral therapy (ART) is poorly defined. This was studied in a cohort in Cape Town, South Africa...
  35. ncbi request reprint Burden of tuberculosis in an antiretroviral treatment programme in sub-Saharan Africa: impact on treatment outcomes and implications for tuberculosis control
    Stephen D Lawn
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, South Africa
    AIDS 20:1605-12. 2006
    ..To determine burden and risk factors for tuberculosis (TB) in an antiretroviral treatment (ART) programme and its impact on ART outcomes...
  36. ncbi request reprint Determinants of mortality and nondeath losses from an antiretroviral treatment service in South Africa: implications for program evaluation
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Clin Infect Dis 43:770-6. 2006
    ..Understanding the determinants of key outcome measures--including death and nondeath losses--would assist in program evaluation and development...
  37. pmc Indoor social networks in a South African township: potential contribution of location to tuberculosis transmission
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    PLoS ONE 7:e39246. 2012
    ..We therefore quantified time spent and contacts met in indoor locations and public transport by residents of a South African township with a very high TB burden...
  38. pmc Treatment outcomes in HIV-infected adolescents attending a community-based antiretroviral therapy clinic in South Africa
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925 Cape Town, South Africa
    BMC Infect Dis 12:21. 2012
    ..The present study therefore compared the treatment outcomes in adolescents with those of young adults at a public sector community-based ART programme in Cape Town, South Africa...
  39. pmc Short-term and long-term risk of tuberculosis associated with CD4 cell recovery during antiretroviral therapy in South Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    AIDS 23:1717-25. 2009
    ..To determine the short-term and long-term risks of tuberculosis (TB) associated with CD4 cell recovery during antiretroviral therapy (ART)...
  40. pmc The impact of gender and income on survival and retention in a South African antiretroviral therapy programme
    Morna Cornell
    University of Cape Town, South Africa
    Trop Med Int Health 14:722-31. 2009
    ..We investigated the association of gender and income with survival and retention in a South African ART programme...
  41. pmc Undiagnosed tuberculosis in a community with high HIV prevalence: implications for tuberculosis control
    Robin Wood
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Health Science Faculty, UCT Observatory, Cape Town 7925, South Africa
    Am J Respir Crit Care Med 175:87-93. 2007
    ..We conducted a cross-sectional survey of pulmonary TB (PTB) and HIV infection in a community of 13,000 with high HIV prevalence and high TB notification rate and a well-functioning DOTS TB control program...
  42. pmc Changes in programmatic outcomes during 7 years of scale-up at a community-based antiretroviral treatment service in South Africa
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 56:e1-8. 2011
    ..To assess sustainability of programmatic outcomes in a community-based antiretroviral therapy (ART) service in South Africa during 7 years of scale-up...
  43. pmc Temporal trends in the characteristics of children at antiretroviral therapy initiation in southern Africa: the IeDEA-SA Collaboration
    Mary Ann Davies
    School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    PLoS ONE 8:e81037. 2013
    ..We examined temporal changes in patient and regimen characteristics at ART start using data from 12 cohorts in 4 countries participating in the IeDEA-SA collaboration...
  44. pmc Predictive Value of Anemia for Tuberculosis in HIV-Infected Patients in Sub-Saharan Africa: An Indication for Routine Microbiological Investigation Using New Rapid Assays
    Andrew D Kerkhoff
    School of Medicine and Health Sciences, The George Washington University, Washington, DC Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa and Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Acquir Immune Defic Syndr 66:33-40. 2014
    ..We assessed the prevalence of TB among those with HIV-related anemia and evaluated new means of rapid TB diagnosis...
  45. pmc When to start antiretroviral therapy in children aged 2-5 years: a collaborative causal modelling analysis of cohort studies from southern Africa
    Michael Schomaker
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    PLoS Med 10:e1001555. 2013
    ....
  46. pmc Rates of tuberculosis transmission to children and adolescents in a community with a high prevalence of HIV infection among adults
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, School of Public Health and Family Medicine, University of Cape Town, Mowbray, Cape Town, South Africa
    Clin Infect Dis 47:349-55. 2008
    ....
  47. ncbi request reprint Rapid scale-up of a community-based HIV treatment service: programme performance over 3 consecutive years in Guguletu, South Africa
    Linda Gail Bekker
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town
    S Afr Med J 96:315-20. 2006
    ..Despite rapid expansion of antiretroviral therapy (ART) in sub-Saharan Africa there are few longitudinal data describing programme performance during rapid scale-up...
  48. ncbi request reprint A 42-week open-label study to assess the pharmacokinetics, antiretroviral activity, and safety of amprenavir or amprenavir plus ritonavir in combination with abacavir and lamivudine for treatment of HIV-infected patients
    Robin Wood
    Somerset Hospital, University of Cape Town, South Africa
    Clin Infect Dis 39:591-4. 2004
    ..regimen, was 6.08 (4.94-7.49) for the twice-daily APV-RTV regimen, and it was 4.19 (2.90-6.08) for the daily APV-RTV regimen. The regimens were well tolerated, which supports APV-RTV as an option for twice-daily or daily therapy for HIV...
  49. ncbi request reprint High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Clin Infect Dis 47:123-30. 2008
    ..A dosage range for AmB of 0.7-1 mg/kg per day is noted in current guidelines, but there are no data comparing 0.7 mg/kg per day with 1 mg/kg per day...
  50. pmc CD4 cell count recovery among HIV-infected patients with very advanced immunodeficiency commencing antiretroviral treatment in sub-Saharan Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 6:59. 2006
    ..Patients accessing antiretroviral treatment (ART) programmes in sub-Saharan Africa frequently have very advanced immunodeficiency. Previous data suggest that such patients may have diminished capacity for CD4 cell count recovery...
  51. doi request reprint Changing patterns in HIV/AIDS stigma and uptake of voluntary counselling and testing services: the results of two consecutive community surveys conducted in the Western Cape, South Africa
    Sumaya Mall
    Department of Psychology, University of Stellenbosch, Cape Town, South Africa
    AIDS Care 25:194-201. 2013
    ..Given the role of HIV/AIDS-associated stigma in influencing choices to access HIV testing, and the benefits associated with HIV testing, interventions to reduce stigma in communities affected by this disease should be encouraged...
  52. pmc An incentivized HIV counseling and testing program targeting hard-to-reach unemployed men in Cape Town, South Africa
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 59:e28-34. 2012
    ..Innovative strategies are needed to increase uptake of testing among men. This study assessed the effectiveness of incentivized mobile HCT in reaching unemployed men in Cape Town, South Africa...
  53. pmc Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    AIDS 23:335-42. 2009
    ..To determine the relationship between mortality risk and the CD4 cell response to antiretroviral therapy (ART)...
  54. pmc Screening for HIV-associated tuberculosis and rifampicin resistance before antiretroviral therapy using the Xpert MTB/RIF assay: a prospective study
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    PLoS Med 8:e1001067. 2011
    ..However, its utility for routine TB screening and detection of rifampicin resistance among HIV-infected patients with advanced immunodeficiency enrolling in antiretroviral therapy (ART) services is unknown...
  55. pmc Efavirenz and rifampicin in the South African context: is there a need to dose-increase efavirenz with concurrent rifampicin therapy?
    Catherine Orrell
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Antivir Ther 16:527-34. 2011
    ..Increasing efavirenz (EFV) dose from 600 mg to 800 mg daily has been suggested with concomitant rifampicin (RFN), as induction of cytochrome P450 isoenzymes may reduce EFV plasma concentrations...
  56. ncbi request reprint Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    AIDS 23:701-6. 2009
    ....
  57. pmc Virologic failure and second-line antiretroviral therapy in children in South Africa--the IeDEA Southern Africa collaboration
    Mary Ann Davies
    School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 56:270-8. 2011
    ..We evaluated the probability and determinants of virologic failure and switching in children in South Africa...
  58. pmc Factors affecting tuberculosis strain success over 10 years in a high TB- and HIV-burdened community
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa, Department of Medicine, University of Cape Town, Cape Town, South Africa, Department of Epidemiology, Mailman School of Public Health, Columbia University, NY, New York, USA, Public Health Research Institute, Tuberculosis Center, New Jersey Medical School, Rutgers, State University of New Jersey, Newark, USA, Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa, National Health Laboratory Service, Cape Town, South Africa, Division of Medical Microbiology, Department of Clinical Laboratory Sciences, University of Cape Town, Cape Town, South Africa and Laboratory of Mycobacterial Immunity and Pathogenesis, Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, USADesmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa, Department of Medicine, University of Cape Town, Cape Town, South Africa, Department of Epidemiology, Mailman School of Public Health, Columbia University, Australia
    Int J Epidemiol 43:1114-22. 2014
    ..Factors associated with Mycobacterium tuberculosis (Mtb) strain success over time in high burdened communities are unknown...
  59. pmc HIV-associated tuberculosis: relationship between disease severity and the sensitivity of new sputum-based and urine-based diagnostic assays
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Med 11:231. 2013
    ..We determined the relationship between disease severity and the sensitivity of new sputum-based and urine-based diagnostic assays...
  60. pmc Resistance in pediatric patients experiencing virologic failure with first-line and second-line antiretroviral therapy
    Catherine Orrell
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town Faculty of Health Sciences, Cape Town, South Africa
    Pediatr Infect Dis J 32:644-7. 2013
    ..Nineteen percent had wild-type virus. Appropriate antiretroviral therapy sequencing in sub-Saharan African children is essential for prolong treatment options. ..
  61. ncbi request reprint Brief report: methods for collecting sexual behaviour information from South African adolescents--a comparison of paper versus personal digital assistant questionnaires
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town Faculty of Health Sciences, PO Box 13801 Mowbray 7705, South Africa
    J Adolesc 30:353-9. 2007
    ..Subjectively, adolescents found the use of PDA to be simple and confidential. PDA may be a useful method to collect sensitive, self-reported information from adolescents in resource-limited settings...
  62. ncbi request reprint Cost of a dedicated ART clinic
    Guy Harling
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town
    S Afr Med J 97:593-6. 2007
    ..The provision of antiretroviral therapy (ART) is being rolled out across South Africa. Little evidence exists on the cost of running clinics for ART provision...
  63. ncbi request reprint Impact of HIV infection on the epidemiology of tuberculosis in a peri-urban community in South Africa: the need for age-specific interventions
    Stephen D Lawn
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    Clin Infect Dis 42:1040-7. 2006
    ..Evaluation of additional control interventions requires detailed understanding of the epidemiological relationship between these diseases at the community level...
  64. doi request reprint Clinical significance of lipoarabinomannan detection in urine using a low-cost point-of-care diagnostic assay for HIV-associated tuberculosis
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    AIDS 26:1635-43. 2012
    ..We determined the characteristics and outcomes of such patients...
  65. pmc Burden of new and recurrent tuberculosis in a major South African city stratified by age and HIV-status
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    PLoS ONE 6:e25098. 2011
    ....
  66. pmc Healthcare utilization of patients accessing an African national treatment program
    Guy Harling
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    BMC Health Serv Res 7:80. 2007
    ..Existing studies of healthcare utilization on HAART have been conducted in the developed world, where HAART is commenced when HIV illness is less advanced...
  67. pmc Childhood tuberculosis infection and disease: a spatial and temporal transmission analysis in a South African township
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Department of Medicine, University of Cape Town
    S Afr Med J 99:738-43. 2009
    ..While adult TB results from both recent and past infection, childhood TB results from recent infection and reflects ongoing transmission despite current TB control strategies...
  68. ncbi request reprint The evolving cost of HIV in South Africa: changes in health care cost with duration on antiretroviral therapy for public sector patients
    Guy Harling
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 45:348-54. 2007
    ..This analysis suggests that the total cost of treatment for patients on ART falls by almost half after 1 year, largely attributable to a reduction in hospital costs...
  69. ncbi request reprint Tuberculosis among HIV-infected patients receiving HAART: long term incidence and risk factors in a South African cohort
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    AIDS 19:2109-16. 2005
    ..To determine the long-term incidence of tuberculosis (TB) and associated risk factors among individuals receiving HAART in South Africa...
  70. pmc Screening for cryptococcal antigenemia in patients accessing an antiretroviral treatment program in South Africa
    Joseph N Jarvis
    Department of Medicine, Division of Infectious Diseases, Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Clin Infect Dis 48:856-62. 2009
    ..Screening for cryptococcal antigen in patients who enroll in ART programs may identify those at risk of cryptococcal meningitis and permit targeted use of preemptive therapy...
  71. pmc Nurse versus doctor management of HIV-infected patients receiving antiretroviral therapy (CIPRA-SA): a randomised non-inferiority trial
    Ian Sanne
    Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Lancet 376:33-40. 2010
    ..We compared outcomes of nurse versus doctor management of ART care for HIV-infected patients...
  72. pmc Linkage to HIV care and antiretroviral therapy in Cape Town, South Africa
    Katharina Kranzer
    Department of Medicine, Faculty of Health Sciences, The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    PLoS ONE 5:e13801. 2010
    ..Programme reports typically focus on loss to follow-up and mortality among patients receiving ART. However, little is known about linkage and retention in care of individuals prior to starting ART...
  73. pmc Molecular epidemiology of Mycobacterium tuberculosis in a South African community with high HIV prevalence
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Cape Town, South Africa
    J Infect Dis 200:1207-11. 2009
    ..The strong association between W-Beijing and HIV infection may have important implications for tuberculosis control...
  74. pmc Treatment interruption in a primary care antiretroviral therapy program in South Africa: cohort analysis of trends and risk factors
    Katharina Kranzer
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Science, University of Cape Town, South Africa
    J Acquir Immune Defic Syndr 55:e17-23. 2010
    ..To investigate antiretroviral treatment (ART) interruption in a long-term treatment cohort in South Africa...
  75. pmc Loss to follow-up and mortality among pregnant women referred to a community clinic for antiretroviral treatment
    Richard Kaplan
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    AIDS 22:1679-81. 2008
    ..This finding highlights the need for programmatic interventions to address retention in care for this patient population...
  76. ncbi request reprint Adolescent and adult participation in an HIV vaccine trial preparedness cohort in South Africa
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    J Adolesc Health 43:8-14. 2008
    ..We analyzed adult and adolescent data from a cohort study conducted to assess the feasibility of involving adolescents and adults in HIV vaccine-related studies...
  77. ncbi request reprint Adolescent HIV prevalence, sexual risk, and willingness to participate in HIV vaccine trials
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    J Adolesc Health 39:642-8. 2006
    ..To determine human immunodeficiency virus (HIV) prevalence, sexual risk behaviors, and attitudes toward HIV vaccine trials among 11-19 year-olds in a peri-urban community near Cape Town, South Africa...
  78. pmc Gender differences in survival among adult patients starting antiretroviral therapy in South Africa: a multicentre cohort study
    Morna Cornell
    Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    PLoS Med 9:e1001304. 2012
    ..Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood. We examined the magnitude of and risk factors for gender differences in mortality on ART...
  79. pmc Delays in starting antiretroviral therapy in patients with HIV-associated tuberculosis accessing non-integrated clinical services in a South African township
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 11:258. 2011
    ..We examined the timing of ART among patients receiving care provided by non-integrated TB and ART services in Cape Town, South Africa...
  80. pmc Force of tuberculosis infection among adolescents in a high HIV and TB prevalence community: a cross-sectional observation study
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 11:156. 2011
    ..However, there are little data assessing incidence of TB infection in adolescents in these settings...
  81. pmc Social mixing patterns within a South African township community: implications for respiratory disease transmission and control
    Simon P Johnstone-Robertson
    Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Western Cape, South Africa
    Am J Epidemiol 174:1246-55. 2011
    ..High numbers of indoor contacts and intergenerational mixing in households and transport may contribute to exceptionally high rates of tuberculosis transmission reported in the community...
  82. pmc Strategies to reduce early morbidity and mortality in adults receiving antiretroviral therapy in resource-limited settings
    Stephen D Lawn
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Curr Opin HIV AIDS 5:18-26. 2010
    ..We focus on articles providing insights into this burden of disease and strategies to address it...
  83. ncbi request reprint Provider-initiated HIV testing increases access of patients with HIV-associated tuberculosis to antiretroviral treatment
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town
    S Afr Med J 101:258-62. 2011
    ..We sought to determine the impact of the introduction of provider-initiated HIV-testing in TB clinics in 2005 on subsequent referrals of patients with HIV-associated TB at a community-based ART service in Cape Town...
  84. ncbi request reprint Short-term risk of AIDS or death in people infected with HIV-1 before antiretroviral therapy in South Africa: a longitudinal study
    Motasim Badri
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory 7925, Cape Town, South Africa
    Lancet 368:1254-9. 2006
    ..Our aim was to investigate these risks in patients who had no access to ART or who were given zidovudine alone...
  85. ncbi request reprint Antiretrovirals and isoniazid preventive therapy in the prevention of HIV-associated tuberculosis in settings with limited health-care resources
    Stephen D Lawn
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Cape Town, South Africa
    Lancet Infect Dis 10:489-98. 2010
    ..Data from randomised controlled trials are needed to underpin further development of public-health policy...
  86. ncbi request reprint Design and evaluation of a drama-based intervention to promote voluntary counseling and HIV testing in a South African community
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Sex Transm Dis 33:524-6. 2006
    ..Voluntary counseling and testing (VCT) services are a major component of HIV prevention and treatment efforts. We developed a drama-based intervention to promote VCT services in a peri-urban community in South Africa...
  87. ncbi request reprint Tuberculosis control in South Africa--will HAART help?
    Stephen D Lawn
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa
    S Afr Med J 96:502-4. 2006
  88. pmc Antiretroviral therapy and TB notification rates in a high HIV prevalence South African community
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 56:263-9. 2011
    ..Antiretroviral therapy (ART) has been proposed as an intervention for reducing tuberculosis (TB) burdens in areas with high HIV prevalence. However, little data is available on the impact of ART on population-level TB...
  89. pmc Cost-effectiveness of highly active antiretroviral therapy in South Africa
    Motasim Badri
    Department of Medicine, Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    PLoS Med 3:e4. 2006
    ..Little information exists on the impact of highly active antiretroviral therapy (HAART) on health-care provision in South Africa despite increasing scale-up of access to HAART and gradual reduction in HAART prices...
  90. pmc Linkage to HIV care from a mobile testing unit in South Africa by different CD4 count strata
    Darshini Govindasamy
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 58:344-52. 2011
    ..The linkage and barriers of linkage to facility-based HIV care from a mobile HIV testing unit have not previously been described...
  91. pmc HIV type-1 clade C resistance genotypes in treatment-naive patients and after first virological failure in a large community antiretroviral therapy programme
    Catherine Orrell
    Desmond Tutu HIV Foundation, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Antivir Ther 14:523-31. 2009
    ..This study aimed to evaluate HIV type-1 (HIV-1) drug resistance pretreatment and in those failing first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy (ART) in South Africa...
  92. ncbi request reprint Substitutions due to antiretroviral toxicity or contraindication in the first 3 years of antiretroviral therapy in a large South African cohort
    Andrew Boulle
    Infectious Disease Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    Antivir Ther 12:753-60. 2007
    ..The patterns and reasons for antiretroviral therapy (ART) drug substitutions are poorly described in resource-limited settings...
  93. ncbi request reprint Early mortality among adults accessing a community-based antiretroviral service in South Africa: implications for programme design
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Cape Town, South Africa
    AIDS 19:2141-8. 2005
    ..To determine rates, risk factors and causes of death among patients accessing a community-based antiretroviral treatment (ART) programme both prior to and following initiation of treatment...
  94. pmc Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007
    Morna Cornell
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa
    AIDS 24:2263-70. 2010
    ..We describe patient outcomes [mortality, loss-to-follow-up (LTFU) and retention] over time in a network of South African ART cohorts...
  95. ncbi request reprint Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: a cohort study
    Motasim Badri
    HIV Clinical Research Unit, Somerset Hospital, University of Cape Town, Green Point 8005, Cape Town, South Africa
    Lancet 359:2059-64. 2002
    ..Studies of the effect of highly active antiretroviral therapy (HAART) on the risk of HIV-1-associated tuberculosis have had variable results. We set out to determine the effect of HAART on the risk of tuberculosis in South Africa...
  96. ncbi request reprint Adherence is not a barrier to successful antiretroviral therapy in South Africa
    Catherine Orrell
    Diana, Princess of Wales HIV Research Unit, Somerset Hospital, University of Cape Town, South Africa
    AIDS 17:1369-75. 2003
    ..To determine adherence of an indigent African HIV-infected cohort initiating antiretroviral therapy (ART); to identify predictors of incomplete adherence (< 95%) and virologic failure (> 400 HIV RNA copies/ml)...
  97. ncbi request reprint Usefulness of total lymphocyte count in monitoring highly active antiretroviral therapy in resource-limited settings
    Motasim Badri
    Somerset Hospital, University of Cape Town, South Africa
    AIDS 17:541-5. 2003
    ..To assess the usefulness of total lymphocyte count (TLC) for monitoring HIV-infected patients receiving highly active antiretroviral therapy. DESIGN Observational cohort study...
  98. pmc Mother-to-child transmission of HIV in a community-based antiretroviral clinic in South Africa
    Felicity C Fitzgerald
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town
    S Afr Med J 100:827-31. 2010
    ..To examine the uptake of ART among pregnant women referred to an ART service and the associated rates and risk factors for vertical HIV transmission...
  99. pmc Six-week randomized controlled trial to compare the tolerabilities, pharmacokinetics, and antiviral activities of GW433908 and amprenavir in human immunodeficiency virus type 1-infected patients
    Robin Wood
    Somerset Hospital, University of Cape Town, Cape Town, South Africa
    Antimicrob Agents Chemother 48:116-23. 2004
    ..GW433908, in combination with abacavir and lamivudine, demonstrated potent antiviral activity and was generally well tolerated over a 4-week period...
  100. doi request reprint The changing natural history of tuberculosis and HIV coinfection in an urban area of hyperendemicity
    Linda Gail Bekker
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Health Science Faculty, University of Cape Town, Cape Town, South Africa
    Clin Infect Dis 50:S208-14. 2010
    ..There is a need for better understanding of the transmission dynamics of TB and the intensity of social interactions, which have exacerbated an HIV and TB epidemic in this community of hyperendemicity...
  101. ncbi request reprint Adolescents and HIV vaccine trials: what are the clinical trial site issues?
    Linda Gail Bekker
    The Desmond Tutu HIV Centre, The Institute of Infectious Disease and Molecular Medicine, University of Cape Town Faculty of Health Sciences, Cape Town 7925, South Africa
    J Int Assoc Physicians AIDS Care (Chic) 4:93-7. 2005
    ..Finally, a number of trial design options exist, and researchers will need to balance the risks and benefits of each, as for all issues surrounding the involvement of adolescents in HIV vaccine trials...

Research Grants2

  1. Cape Town Clinical Trials Unit (CT-CTU) for HIV/AIDS Prevention & Treatment
    Robin Wood; Fiscal Year: 2007
    ..in the Desmond Tutu HIV Centre (DTHC) at the University of Cape Town (UCT) under the leadership of Professor Robin Wood, one of South Africa's leading experts in HIV care and treatment...
  2. Cape Town Clinical Trials Unit (CT-CTU) for HIV/AIDS Prevention & Treatment
    Robin Wood; Fiscal Year: 2008
    ..in the Desmond Tutu HIV Centre (DTHC) at the University of Cape Town (UCT) under the leadership of Professor Robin Wood, one of South Africa's leading experts in HIV care and treatment...