- Mitochondrial impairment observed in fibroblasts from South African Parkinson's disease patients with parkin mutationsCelia van der Merwe
Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa Electronic address
Biochem Biophys Res Commun 447:334-40. 2014..Involvement of mitochondria as a key role player in PD pathogenesis will have important implications for the design of new and more effective therapies. ..
- Factors influencing the development of early- or late-onset Parkinson's disease in a cohort of South African patientsCelia van der Merwe
Division of Molecular Biology and Human Genetics, Stellenbosch University, Tygerberg, Western Cape, South Africa
S Afr Med J 102:848-51. 2012..PD can be categorised into early-onset PD (EOPD) with an age at onset (AAO) of ≤50 years and late-onset PD (LOPD) with an AAO of 50 years...
- Mutations in the parkin gene are a minor cause of Parkinson's disease in the South African populationWilliam L Haylett
Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Cape Town, South Africa
Parkinsonism Relat Disord 18:89-92. 2012..Further investigations of the molecular etiology of PD in the unique South African population, particularly the Black African and mixed ancestry sub-populations, are warranted...