Research Topics
| Johan B UbbinkSummaryAffiliation: University of Pretoria Country: South Africa Publications
| Collaborators |
Detail Information
Publications
The effect of a subnormal vitamin B-6 status on homocysteine metabolismJ B Ubbink
Department of Chemistry Pathology, University of Pretoria, South Africa
J Clin Invest 98:177-84. 1996..01) reduced in both groups after vitamin supplementation. It is concluded that a vitamin B-6 deficiency may contribute to impaired transsulfuration and an abnormal methionine load test, which is associated with premature vascular disease...
Homocysteine and ischaemic heart disease in the Caerphilly cohortJ B Ubbink
University of Pretoria, Department of Chemical Pathology, Faculty of Medicine, South Africa
Atherosclerosis 140:349-56. 1998..05)...
Should all elderly people receive folate supplements?J B Ubbink
Department of Chemical Pathology, University of Pretoria, South Africa
Drugs Aging 13:415-20. 1998..The daily folate supplement should be at least 0.5 mg/day and it should never be used as a surrogate for a diet rich in fruit and vegetables...
Comparison of three different plasma homocysteine assays with gas chromatography-mass spectrometryJ B Ubbink
Department of Chemical Pathology, University of Pretoria, P O Box 2034, Pretoria 0001, South Africa
Clin Chem 45:670-5. 1999..Various methods are available to measure plasma total homocyst(e)ine (tHcy) concentrations, but whether plasma tHcy assays may be used interchangeably is not known...
Assay methods for the measurement of total homocyst(e)ine in plasmaJ B Ubbink
Department of Chemical Pathology, University of Pretoria, South Africa
Semin Thromb Hemost 26:233-41. 2000..Between-method and between-laboratory variations in serum tHcy analysis are not yet satisfactory; certified reference material and standardization of the plasma tHcy assay will be essential to reduce between-laboratory bias...
Variability of post-methionine load plasma homocysteine assaysJohan B Ubbink
Department of Chemical Pathology, University of Pretoria, P O Box 2034, South Africa
Clin Chim Acta 330:111-9. 2003..Lack of standardization impedes inter-laboratory comparisons. Criteria based on biological variation are suggested to standardize the methionine load test...
Hyperhomocyst(e)inemia is an important risk factor for vascular disease in subjects with high-molecular weight apo(a) isoformsRhena Delport
Department of Chemical Pathology, Institute of Pathology, University of Pretoria, Pretoria, South Africa
Cardiovasc J S Afr 15:207-13. 2004..92; 95% CI: 0.51-7.24. CONCLUSIONS: We conclude that hyperhomocyst(e)inemia is an important risk factor in individuals with high-molecular weight apo(a) isoforms...
Biological variation in sweat sodium chloride conductivityDa elene van der Merwe
Department of Chemical Pathology, Faculty of Medicine, University of Pretoria, South Africa
Ann Clin Biochem 39:39-43. 2002..The aim of this study was to determine the components of biological variation for sweat sodium chloride conductivity and to apply biological variation parameters in the interpretation of sweat conductivity...
Physiologic mechanisms to maintain methionine status during protein malnutritionJohan B Ubbink
Nutrition 18:96-7. 2002
