L O Somova

Summary

Affiliation: University of Durban-Westville
Country: South Africa

Publications

  1. ncbi Mongolian gerbil (Meriones unguiculatus) as a model of cerebral infarction for testing new therapeutic agents
    L I Somova
    Department of Human Physiology, University of Durban Westville, South Africa
    Methods Find Exp Clin Pharmacol 22:203-10. 2000
  2. ncbi Antioxidant status of the hypertrophic heart of Dahl hypertensive rat as a model for evaluation of antioxidants
    L I Somova
    Department of Human Physiology and Electron Microscope Unit, University of Durban Westville, South Africa
    Methods Find Exp Clin Pharmacol 23:5-12. 2001
  3. ncbi Cardiovascular and diuretic activity of kaurene derivatives of Xylopia aethiopica and Alepidea amatymbica
    L I Somova
    Department of Human Physiology, University of Durban Westville, Private Bag X54001, Durban, South Africa
    J Ethnopharmacol 77:165-74. 2001
  4. ncbi Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves
    L I Somova
    Department of Human Physiology, University of Durban Westville, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 84:299-305. 2003
  5. ncbi Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension
    L O Somova
    Department of Human Physiology, University of Durban Westville, Durban, South Africa
    Phytomedicine 10:115-21. 2003
  6. ncbi Cardiotonic and antidysrhythmic effects of oleanolic and ursolic acids, methyl maslinate and uvaol
    L I Somova
    Department of Human Physiology University of Durban Westville, Durban, South Africa
    Phytomedicine 11:121-9. 2004
  7. ncbi The role of C-reactive protein in ischemia/reperfusion injury and preconditioning in a rat model of myocardial infarction
    A Valtchanova-Matchouganska
    Tara Hospital, Morose Center 50 Saxon Rd, Hurlingham, Johannesburg 2194, South Africa
    Life Sci 75:901-10. 2004

Collaborators

Detail Information

Publications7

  1. ncbi Mongolian gerbil (Meriones unguiculatus) as a model of cerebral infarction for testing new therapeutic agents
    L I Somova
    Department of Human Physiology, University of Durban Westville, South Africa
    Methods Find Exp Clin Pharmacol 22:203-10. 2000
    ..Experimental infarction in gerbil recreates the ischemic conditions causing stroke in humans. The animal model may be used for evaluating the efficacy of therapeutic agents that may ameliorate the condition in man...
  2. ncbi Antioxidant status of the hypertrophic heart of Dahl hypertensive rat as a model for evaluation of antioxidants
    L I Somova
    Department of Human Physiology and Electron Microscope Unit, University of Durban Westville, South Africa
    Methods Find Exp Clin Pharmacol 23:5-12. 2001
    ..Before the Dahl rat can be considered as a suitable model for testing new cardiac antioxidants, a full characterization of the level of cardiac oxygen free radicals is required...
  3. ncbi Cardiovascular and diuretic activity of kaurene derivatives of Xylopia aethiopica and Alepidea amatymbica
    L I Somova
    Department of Human Physiology, University of Durban Westville, Private Bag X54001, Durban, South Africa
    J Ethnopharmacol 77:165-74. 2001
    ..Further experiments are needed to elaborate the exact mechanisms of the hypotensive and diuretic effects of diterpene kaurenoids...
  4. ncbi Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves
    L I Somova
    Department of Human Physiology, University of Durban Westville, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 84:299-305. 2003
    ..GO, OA and CT isolates could provide an effective and cheap treatment of this particular, most common type of salt-sensitive hypertension in the African population...
  5. ncbi Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension
    L O Somova
    Department of Human Physiology, University of Durban Westville, Durban, South Africa
    Phytomedicine 10:115-21. 2003
    ..Except for the antihyperlipidemic effects, the other described above in vivo antihypertensive effects of OA and UA are reported for the first time and the underlying mechanisms are currently under investigation...
  6. ncbi Cardiotonic and antidysrhythmic effects of oleanolic and ursolic acids, methyl maslinate and uvaol
    L I Somova
    Department of Human Physiology University of Durban Westville, Durban, South Africa
    Phytomedicine 11:121-9. 2004
    ....
  7. ncbi The role of C-reactive protein in ischemia/reperfusion injury and preconditioning in a rat model of myocardial infarction
    A Valtchanova-Matchouganska
    Tara Hospital, Morose Center 50 Saxon Rd, Hurlingham, Johannesburg 2194, South Africa
    Life Sci 75:901-10. 2004
    ..This could be a promising perspective in clinical interventions against ischemia/reperfusion injuries of the heart...