Robert M Smith

Summary

Affiliation: University of Stellenbosch
Country: South Africa

Publications

  1. ncbi request reprint Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning
    Robert M Smith
    Hatter Institute for Cardiology Research, Faculty of Health Sciences, University of Cape Town Observatory, Cape Heart Centre, Chris Barnard Building, Cape Town 7925, South Africa
    Cardiovasc Res 63:611-6. 2004
  2. ncbi request reprint Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene
    Robert M Smith
    Hatter Institute for Cardiology Research, MRC Inter University Cape Heart Group, University of Cape Town Medical School, Observatory 7925, South Africa
    Cardiovasc Res 55:553-60. 2002
  3. ncbi request reprint Innate immunity and cardiac preconditioning: a putative intrinsic cardioprotective program
    Robert M Smith
    Hatter Institute for Cardiology Research, MRC Inter University Cape Heart Group, University of Cape Town Medical School, South Africa
    Cardiovasc Res 55:474-82. 2002
  4. doi request reprint The inflammatory response to skeletal muscle injury: illuminating complexities
    Carine Smith
    Department of Physiological Sciences, Stellenbosch University, Matieland, South Africa
    Sports Med 38:947-69. 2008
  5. ncbi request reprint Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection
    Sandrine Lecour
    Hatter Institute for Cardiology Research, MRC Inter University Cape Heart Group, University of Cape Town Medical School, South Africa
    J Mol Cell Cardiol 34:509-18. 2002
  6. ncbi request reprint TNFalpha-induced cytoprotection requires the production of free radicals within mitochondria in C2C12 myotubes
    Lydia Lacerda
    Hatter Institute for Cardiology Research, University of Cape Town, South Africa
    Life Sci 79:2194-201. 2006

Detail Information

Publications6

  1. ncbi request reprint Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning
    Robert M Smith
    Hatter Institute for Cardiology Research, Faculty of Health Sciences, University of Cape Town Observatory, Cape Heart Centre, Chris Barnard Building, Cape Town 7925, South Africa
    Cardiovasc Res 63:611-6. 2004
    ..To evaluate the functional requirement of signal transducer and activator of transcription-3 (STAT-3) in cardiac myocyte tolerance to ischemia (I) and in classical preconditioning...
  2. ncbi request reprint Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene
    Robert M Smith
    Hatter Institute for Cardiology Research, MRC Inter University Cape Heart Group, University of Cape Town Medical School, Observatory 7925, South Africa
    Cardiovasc Res 55:553-60. 2002
    ..Moreover, whether TNFalpha is required to induce the ischemic preconditioning phenotype has not been determined...
  3. ncbi request reprint Innate immunity and cardiac preconditioning: a putative intrinsic cardioprotective program
    Robert M Smith
    Hatter Institute for Cardiology Research, MRC Inter University Cape Heart Group, University of Cape Town Medical School, South Africa
    Cardiovasc Res 55:474-82. 2002
    ....
  4. doi request reprint The inflammatory response to skeletal muscle injury: illuminating complexities
    Carine Smith
    Department of Physiological Sciences, Stellenbosch University, Matieland, South Africa
    Sports Med 38:947-69. 2008
    ....
  5. ncbi request reprint Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection
    Sandrine Lecour
    Hatter Institute for Cardiology Research, MRC Inter University Cape Heart Group, University of Cape Town Medical School, South Africa
    J Mol Cell Cardiol 34:509-18. 2002
    ..In conclusion, TNF alpha activates preconditioning-like tolerance against infarction and contractile dysfunction. This cardioprotection is mediated, in part, via activation of novel sphingolipid signaling intermediates...
  6. ncbi request reprint TNFalpha-induced cytoprotection requires the production of free radicals within mitochondria in C2C12 myotubes
    Lydia Lacerda
    Hatter Institute for Cardiology Research, University of Cape Town, South Africa
    Life Sci 79:2194-201. 2006
    ..In conclusion, TNFalpha-induced ROS generation can occur within the mitochondria, resulting in temporal mitochondrial perturbations which may initiate the cytoprotective effect of TNFalpha...