Research Topics
Species | John M PettiforSummaryAffiliation: University of the Witwatersrand Country: South Africa Publications
| Collaborators
|
Detail Information
Publications
RicketsJohn M Pettifor
MRC Mineral Metabolism Research Unit, Department of Paediatrics, University of the Witwatersrand, P.O. Bertsham 2013, South Africa
Calcif Tissue Int 70:398-9. 2002- Vitamin D metabolism in a frugivorous nocturnal mammal, the Egyptian fruit bat (Rousettus aegyptiacus)Meropi Cavaleros
Department of Paediatrics, University of the Witwatersrand, Johannesburg, 7 York Road, 2193, South Africa
Gen Comp Endocrinol 133:109-17. 2003.... - Nutritional rickets: deficiency of vitamin D, calcium, or both?John M Pettifor
Medical Research Council Mineral Metabolism Research Unit, Department of Paediatrics, Chris Hani Baragwanath Hospital and the University of the Witwatersrand, Johannesburg, South Africa
Am J Clin Nutr 80:1725S-9S. 2004..Dietary calcium deficiency and vitamin D deficiency represent 2 ends of the spectrum for the pathogenesis of nutritional rickets, with a combination of the 2 in the middle... - Rickets and vitamin D deficiency in children and adolescentsJohn M Pettifor
Department of Paediatrics, Chris Hani Baragwanath Hospital, Soweto 2013, South Africa
Endocrinol Metab Clin North Am 34:537-53, vii. 2005..The worldwide nature of the problem is described. Preventive strategies are discussed, and various treatment options are provided... - Comment: childhood nutrition and social supportJohn M Pettifor
Department of Paediatrics, University of Witwatersrand and Chris Hani Baragwanath Hospital, South Africa
Scand J Public Health Suppl 69:128-9. 2007 
Hypophosphatemic rickets: unraveling the role of FGF23John M Pettifor
MRC Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, 7 York Rd, Parktown, Johannesburg 2193, South Africa
Calcif Tissue Int 91:297-306. 2012..Phase 1 and phase 2 trials in humans with X-linked hypophosphatemic rickets are currently under way...- Vitamin D &/or calcium deficiency rickets in infants & children: a global perspectiveJohn M Pettifor
Department of Paediatrics, Chris Hani Baragwanath Hospital and the University of the Witwatersrand Johannesburg, South Africa
Indian J Med Res 127:245-9. 2008..Yet we are still unclear as to the factors which predispose some children to the disease... - The role of vitamin D in paediatric bone healthJohn M Pettifor
MRC Mineral Metabolism Research Unit, Department of Paediatrics, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, York Road, Parktown 2193, Johannesburg, South Africa
Best Pract Res Clin Endocrinol Metab 25:573-84. 2011..Further studies are needed in these areas prior to definitive conclusions are drawn about the optimal vitamin D requirements and circulating 25(OH)D concentrations for foetal, infant and childhood bone health... 
What's new in hypophosphataemic rickets?John M Pettifor
MRC Mineral Metabolism Research Unit, Department of Paediatrics, Chris Hani Baragwanath Hospital, University of the Witwatersrand, PO Bertsham 2013, Johannesburg, South Africa
Eur J Pediatr 167:493-9. 2008..Although our understanding of the interrelationships is far from complete, it raises the possibilities of improved therapeutic agents in the long-term, and has resulted in improved diagnostic abilities in the short-term...- Nutritional status and HIV in rural South African childrenElizabeth W Kimani-Murage
MRC Wits Rural Public Health and Health Transitions Research Unit Agincourt, School of Public Health, Faculty of Health Sciences, University of Witwatersrand, South Africa
BMC Pediatr 11:23. 2011..This study describes HIV prevalence in children, patterns of malnutrition by HIV status and determinants of nutritional status... - Heterogeneity of fracture pathogenesis in urban South African children: the birth to twenty cohortKebashni Thandrayen
MRC Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa
J Bone Miner Res 26:2834-42. 2011..No contributing factors in black males and females were found, and needs further elucidation... - Infant programming of bone size and bone mass in 10-year-old black and white South African childrenLinda Vidulich
MRC Mineral Metabolism Research Unit, Department of Paediatrics, University of the Witwatersrand, Johannesburg, South Africa
Paediatr Perinat Epidemiol 21:354-62. 2007.... - Factors influencing the vitamin D status of 10-year-old urban South African childrenMachuene A Poopedi
MRC Mineral Metabolism Research Unit and Birth to Twenty Research Programme, Department of Paediatrics and Child Health, Chris Hani Baragwanath Hospital, The University of the Witwatersrand, PO Bertsham, 2013 Johannesburg, South Africa
Public Health Nutr 14:334-9. 2011..Assessment of vitamin D status in a cohort of healthy 10-year-old urban children and the factors that influence vitamin D status in these children... - Predictors of adolescent weight status and central obesity in rural South AfricaElizabeth W Kimani-Murage
MRC Wits Rural Public Health and Health Transitions Research Unit Agincourt, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Public Health Nutr 14:1114-22. 2011..To investigate predictors of adolescent obesity in rural South Africa... - Current socio-economic measures, and not those measured during infancy, affect bone mass in poor urban South african childrenShane A Norris
Department of Paediatrics, MRC Mineral Metabolism Research Unit, University of the Witwatersrand, Johannesburg, South Africa
J Bone Miner Res 23:1409-16. 2008..SES has a significant independent effect on whole body BMC through its impact on BA. This suggests that poverty alleviation policies in South Africa could have a positive effect on bone health... - Changes in dietary habits and eating practices in adolescents living in urban South Africa: the birth to twenty cohortAlison Feeley
Department of Paediatrics, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Nutrition 28:e1-6. 2012..To assess changes in the dietary habits and eating practices of a longitudinal cohort of adolescents over a 5-y period living in Soweto and Johannesburg... - Maternal vitamin D status: implications for the development of infantile nutritional ricketsKebashni Thandrayen
MRC Mineral Metabolism Research Unit, Department of Pediatrics, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa
Endocrinol Metab Clin North Am 39:303-20, table of contents. 2010..Operational research studies are needed to understand the best methods of implementing supplementation programs and the factors that are likely to impede their success... - Implications of adopting the WHO 2006 Child Growth Standards: case study from urban South Africa, the Birth to Twenty cohortShane A Norris
MRC Mineral Metabolism Research Unit, Paediatrics, University of Witwatersrand and Chris Hani Baragwanath Hospital, Johannesburg, South Africa
Ann Hum Biol 36:21-7. 2009..The World Health Organization (WHO) recently developed growth standards to overcome the limitations of previous references... - Determinants of bone size and strength in 13-year-old South African children: the influence of ethnicity, sex and pubertal maturationLisa K Micklesfield
MRC Mineral Metabolism Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa
Bone 48:777-85. 2011..South African black children have wider diaphyseal regions of appendicular bones with greater measures of bone strength... - The prevalence of stunting, overweight and obesity, and metabolic disease risk in rural South African childrenElizabeth W Kimani-Murage
MRC Wits Rural Public Health and Health Transitions Research Unit Agincourt, School of Public Health, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa
BMC Public Health 10:158. 2010..This study aimed to investigate the prevalence and patterns of stunting and overweight/obesity, and hence risk for metabolic disease, in a group of children and adolescents in rural South Africa... - Comparisons of body size, composition, and whole body bone mass between North American and South African childrenLisa K Micklesfield
UCT MRC Research Unit for Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, South Africa
J Bone Miner Res 22:1869-77. 2007..Our findings support the role of genetic and environmental influences in the determination of bone mass in prepubertal children... - Nutritional rickets in developing countriesJohn M Pettifor
Department of Paediatrics, Chris Hani Baragwanath Hospital, Johannesburg, South Africa
Forum Nutr 56:176-8. 2003 - Effect of ethnicity and sex on the growth of the axial and appendicular skeleton of children living in a developing countryLukhanyo H Nyati
Medical Research Council Mineral Metabolism Research Unit, Department of Pediatrics and Child Health, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
Am J Phys Anthropol 130:135-41. 2006..In conclusion, there is a differential effect of ethnicity and sex on the growth of the axial and appendicular skeletons, and regional segment length is a better predictor of site-specific bone mass than stature... - Investigation into longitudinal dietary behaviours and household socio-economic indicators and their association with BMI Z-score and fat mass in South African adolescents: the Birth to Twenty (Bt20) cohortAlison B Feeley
MRC Wits Developmental Pathways for Health Research Unit, School of Medicine, University of the Witwatersrand, 7 York Road, Parktown, 2193 Johannesburg, South Africa
Public Health Nutr 16:693-703. 2013..The present study aimed to assess the relationship between dietary habits, change in socio-economic status and BMI Z-score and fat mass in a cohort of South African adolescents... - Maternal vitamin D status: implications for the development of infantile nutritional ricketsKebashni Thandrayen
MRC Developmental Pathways for Health Research Unit, Deptartment of Pediatrics, Chris Hani Baragwanath Hospital, PO Bertsham, Johannesburg 2013, South Africa
Rheum Dis Clin North Am 38:61-79. 2012..Operational research studies also need to be conducted to understand the best methods of implementing supplementation programs and the factors that are likely to impede their success... - Regression equations to estimate percentage body fat in African prepubertal children aged 9 yNoel Cameron
Department of Human Sciences, Loughborough University, United Kingdom
Am J Clin Nutr 80:70-5. 2004..These equations contain methodologic problems that could make them inappropriate for African children... - Rickets: an overview and future directions, with special reference to Bangladesh. A summary of the Rickets Convergence Group meeting, Dhaka, 26-27 January 2006Thierry Craviari
Centre Hospitalier de Gap, Gap, France
J Health Popul Nutr 26:112-21. 2008..Effective preventive measures that can feasibly reach entire communities are needed, and these may differ between various affected regions... - Pediatric vitamin D and calcium nutrition in developing countriesPhilip R Fischer
Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Rev Endocr Metab Disord 9:181-92. 2008.... - Comparison of cross-sectional geometry of the proximal femur in white and black women from Detroit and JohannesburgDorothy A Nelson
Department of Internal Medicine, Wayne State University, Detroit, Michigan 48201, USA
J Bone Miner Res 19:560-5. 2004..S. black (n = 86) and white (n = 151) and South African black (n = 60) and white (n = 48) postmenopausal women. Results are consistent with greater bone strength in the black groups in both countries... - Nutritional rickets in ichthyosis and response to calcipotrieneTom D Thacher
Department of Family Medicine, Jos University Teaching Hospital, Jos, Nigeria
Pediatrics 114:e119-23. 2004..Calcipotriene does not seem to be effective in reversing systemic vitamin D deficiency but can be effective in improving the severity of skin disease in children with ichthyosis... - Calcium absorption in Nigerian children with ricketsMariaelisa Graff
Department of Foods and Nutrition, University of Utah, Salt Lake City and Chemical Pathology, University of Jos, Jos, Nigeria
Am J Clin Nutr 80:1415-21. 2004..Calcium absorption may be inadequate to meet the skeletal demands of children with rickets during the active phase of the disease, despite being similar to that of control children... - Stunting at 2 years in relation to body composition at 9 years in African urban childrenNoel Cameron
Department of Human Sciences, Loughborough University, Loughborough LE11 3TU, United Kingdom
Obes Res 13:131-6. 2005..To determine whether African urban children who were stunted at 2 years of age demonstrated an altered body composition by the end of childhood, before entering puberty, at 9 years of age... - Nutritional rickets around the world: causes and future directionsTom D Thacher
Department of Family Medicine, Jos University Teaching Hospital, Nigeria
Ann Trop Paediatr 26:1-16. 2006..Vitamin D supplementation alone might not prevent or treat rickets in populations with limited calcium intake... - Case-control study of breast milk calcium in mothers of children with and without nutritional ricketsTom D Thacher
Department of Family Medicine, Jos University Teaching Hospital, Nigeria
Acta Paediatr 95:826-32. 2006..20) after adjusting for height, weight, and bone area (P=0.028). CONCLUSION: Reduced breast-milk calcium concentration may contribute to a reduced calcium intake in infancy and predispose children to nutritional rickets... - Rickets: vitamin D and calcium deficiencyTom D Thacher
J Bone Miner Res 22:638; author reply 639. 2007 - Vitamin D and/or calcium deficiency rickets in infants and children: a concern for developing countries?John M Pettifor
Indian Pediatr 44:893-5. 2007 - Adaptation of calcium absorption during treatment of nutritional rickets in Nigerian childrenGloria E Oramasionwu
Department of Pediatrics, USDA ARS Children s Nutrition Research Center, Baylor College of Medicine and Texas Children s Hospital, Houston, Texas 77030, USA
Br J Nutr 100:387-92. 2008..These data demonstrate that although absorptive capacity is regulated by supplementation, recovery from rickets likely occurs through efficient use of both dietary and supplemental Ca... - FGF23 is elevated in Gambian children with ricketsAnn Prentice
MRC Keneba, The Gambia
Bone 42:788-97. 2008.... - Early response to vitamin D2 in children with calcium deficiency ricketsTom D Thacher
Department of Family Medicine, Jos University Teaching Hospital, University of Jos, Jos, Nigeria
J Pediatr 149:840-4. 2006..Assessment of vitamin D sufficiency in persons or communities may need to be adjusted for habitual dietary calcium intake... - Vertical HIV transmission in South Africa: translating research into policy and practiceSalim Abdool Karim
University of Natal, 4041, South Africa
Lancet 359:992-3. 2002 - The usefulness of clinical features to identify active ricketsTom D Thacher
Department of Family Medicine, Jos University Teaching Hospital, Nigeria
Ann Trop Paediatr 22:229-37. 2002..We conclude that clinical features can be used to identify children with active rickets...