J A O Ojewole

Summary

Affiliation: University of KwaZulu-Natal
Country: South Africa

Publications

  1. ncbi Hypoglycaemic effect of Clausena anisata (Willd) Hook methanolic root extract in rats
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of Durban Westville, Durban 4000, South Africa
    J Ethnopharmacol 81:231-7. 2002
  2. ncbi Anticonvulsant effect of Persea americana Mill (Lauraceae) (Avocado) leaf aqueous extract in mice
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 20:696-700. 2006
  3. ncbi Antiinflammatory and analgesic effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rats and mice
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 28:441-6. 2006
  4. ncbi Analgesic, anti-inflammatory and hypoglycaemic effects of Rhus chirindensis (Baker F.) [Anacardiaceae] stem-bark aqueous extract in mice and rats
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 113:338-45. 2007
  5. ncbi Uterolytic effect of Hypoxis hemerocallidea Fisch. & C.A. Mey. (Hypoxidaceae) corm [;African Potato'] aqueous extract
    Agatha Nyinawumuntu
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, South Africa
    J Smooth Muscle Res 44:167-76. 2008
  6. doi Sclerocarya birrea (A. Rich) Hochst. ['Marula'] (Anacardiaceae): a review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Phytother Res 24:633-9. 2010
  7. ncbi Analgesic and antiinflammatory effects of mollic acid glucoside, a 1 alpha-hydroxycycloartenoid saponin extractive from Combretum molle R. Br. ex G. Don (Combretaceae) leaf
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 22:30-5. 2008
  8. ncbi Antinociceptive, anti-inflammatory and antidiabetic effects of Bryophyllum pinnatum (Crassulaceae) leaf aqueous extract
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 99:13-9. 2005
  9. ncbi Antinociceptive, antiinflammatory and antidiabetic effects of Leonotis leonurus (L.) R. BR. [Lamiaceae] leaf aqueous extract in mice and rats
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 27:257-64. 2005
  10. ncbi Antinociceptive, anti-inflammatory and antidiabetic properties of Hypoxis hemerocallidea Fisch. & C.A. Mey. (Hypoxidaceae) corm ['African Potato'] aqueous extract in mice and rats
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    J Ethnopharmacol 103:126-34. 2006

Collaborators

Detail Information

Publications57

  1. ncbi Hypoglycaemic effect of Clausena anisata (Willd) Hook methanolic root extract in rats
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of Durban Westville, Durban 4000, South Africa
    J Ethnopharmacol 81:231-7. 2002
    ..anisata root in the management and/or control of adult-onset, Type-2 diabetes mellitus in some communities of South Africa...
  2. ncbi Anticonvulsant effect of Persea americana Mill (Lauraceae) (Avocado) leaf aqueous extract in mice
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 20:696-700. 2006
    ....
  3. ncbi Antiinflammatory and analgesic effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rats and mice
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 28:441-6. 2006
    ....
  4. ncbi Analgesic, anti-inflammatory and hypoglycaemic effects of Rhus chirindensis (Baker F.) [Anacardiaceae] stem-bark aqueous extract in mice and rats
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 113:338-45. 2007
    ....
  5. ncbi Uterolytic effect of Hypoxis hemerocallidea Fisch. & C.A. Mey. (Hypoxidaceae) corm [;African Potato'] aqueous extract
    Agatha Nyinawumuntu
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, South Africa
    J Smooth Muscle Res 44:167-76. 2008
    ....
  6. doi Sclerocarya birrea (A. Rich) Hochst. ['Marula'] (Anacardiaceae): a review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Phytother Res 24:633-9. 2010
    ..birrea's chemical constituents, as well as its ethnomedicinal, pharmacological and toxicological properties...
  7. ncbi Analgesic and antiinflammatory effects of mollic acid glucoside, a 1 alpha-hydroxycycloartenoid saponin extractive from Combretum molle R. Br. ex G. Don (Combretaceae) leaf
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 22:30-5. 2008
    ....
  8. ncbi Antinociceptive, anti-inflammatory and antidiabetic effects of Bryophyllum pinnatum (Crassulaceae) leaf aqueous extract
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 99:13-9. 2005
    ..The different flavonoids, polyphenols, triterpenoids and other chemical constituents of the herb are speculated to account for the observed antinociceptive, anti-inflammatory and antidiabetic properties of the plant...
  9. ncbi Antinociceptive, antiinflammatory and antidiabetic effects of Leonotis leonurus (L.) R. BR. [Lamiaceae] leaf aqueous extract in mice and rats
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 27:257-64. 2005
    ....
  10. ncbi Antinociceptive, anti-inflammatory and antidiabetic properties of Hypoxis hemerocallidea Fisch. & C.A. Mey. (Hypoxidaceae) corm ['African Potato'] aqueous extract in mice and rats
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    J Ethnopharmacol 103:126-34. 2006
    ....
  11. ncbi Antiinflammatory, analgesic and hypoglycemic effects of Mangifera indica Linn. (Anacardiaceae) stem-bark aqueous extract
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 27:547-54. 2005
    ....
  12. ncbi Analgesic and anticonvulsant properties of Tetrapleura tetraptera (Taub) (Fabaceae) fruit aqueous extract in mice
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 19:1023-9. 2005
    ....
  13. ncbi Hypoglycemic and hypotensive effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 27:689-95. 2005
    ....
  14. ncbi Vasodilatory and hypoglycaemic effects of two pyrano-isoflavone extractives from Eriosema kraussianum N. E. Br. [Fabaceae] rootstock in experimental rat models
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Scottsville, Durban 4000, South Africa
    Phytochemistry 67:610-7. 2006
    ..The findings of this laboratory animal study indicate that the two hydro-ethanol extractives of E. kraussianum (K1 and K2) possess hypoglycaemic and secondary, vasorelaxant effects in the experimental paradigms used...
  15. ncbi Anti-inflammatory and hypoglycaemic effects of Tetrapleura tetraptera (Taub) [Fabaceae] fruit aqueous extract in rats
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 95:177-82. 2004
    ....
  16. ncbi Evaluation of the analgesic, anti-inflammatory and anti-diabetic properties of Sclerocarya birrea (A. Rich.) Hochst. stem-bark aqueous extract in mice and rats
    John A O Ojewole
    Department of Pharmacology, University of Durban Westville, Durban 4000, South Africa
    Phytother Res 18:601-8. 2004
    ....
  17. ncbi Bronchorelaxant property of 'African potato' (Hypoxis hemerocallidea corm) aqueous extract in vitro
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban 4000, South Africa
    J Smooth Muscle Res 45:241-8. 2009
    ....
  18. doi Antidiarrhoeal activity of Hypoxis hemerocallidea Fisch. & C. A. Mey. (Hypoxidaceae) Corm ('African potato') aqueous extract in rodents
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 23:965-71. 2009
    ..This finding supports the use of 'African potato' as a natural supplementary remedy for the treatment, management and/or control of diarrhoea in some rural communities of southern Africa...
  19. doi Hypoglycaemic effect of mollic acid glucoside, a 1alpha-hydroxycycloartenoid saponin extractive from Combretum molle R. Br. ex G. Don (Combretaceae) leaf, in rodents
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban 4000, South Africa
    J Nat Med 63:117-23. 2009
    ..These findings lend pharmacological credence to the folkloric, ethnomedical uses of the plant's leaf in the management and/or control of diabetes mellitus in some rural communities of southern Africa...
  20. ncbi Antidiarrhoeal activity of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rodents
    John A O Ojewole
    Department of Pharmacology, University of KwaZulu Natal, Durban, South Africa
    J Smooth Muscle Res 44:195-207. 2008
    ....
  21. doi Anticonvulsant effect of Rhus chirindensis (Baker F.) (Anacardiaceae) stem-bark aqueous extract in mice
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 117:130-5. 2008
    ..In conclusion, the findings of this study lend pharmacological credence to the suggested folkloric, ethnomedical uses of Rhus chirindensis in the management of childhood convulsions and epilepsy in some rural communities of South Africa...
  22. ncbi Anticonvulsant property of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Brain Res Bull 75:126-32. 2008
    ....
  23. ncbi Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban, South Africa
    Phytother Res 20:764-72. 2006
    ....
  24. ncbi Analgesic, anti-inflammatory and hypoglycaemic effects of Securidaca longepedunculata (Fresen.) [Polygalaceae] root-bark aqueous extract
    J A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Inflammopharmacology 16:174-81. 2008
    ..longepedunculata root-bark in the treatment, management and/or control of painful, arthritic, inflammatory conditions, as well as in the management and/or control of type 2 diabetes mellitus in some rural communities of South Africa...
  25. ncbi Anticonvulsant activity of Hypoxis hemerocallidea Fisch. & C. A. Mey. (Hypoxidaceae) corm ('African potato') aqueous extract in mice
    John A O Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 22:91-6. 2008
    ....
  26. ncbi Analgesic, antiinflammatory and hypoglycemic effects of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 26:409-16. 2004
    ....
  27. doi Effects of Persea americana Mill (Lauraceae) ["Avocado"] ethanolic leaf extract on blood glucose and kidney function in streptozotocin-induced diabetic rats and on kidney cell lines of the proximal (LLCPK1) and distal tubules (MDBK)
    M Gondwe
    Discipline of Human Physiology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 30:25-35. 2008
    ..These results indicate not only the basis of the ethnomedicinal use of P. americana leaf extract in diabetes management, but also of need for further studies to identify and evaluate the safety of PAE's bioactive compounds...
  28. ncbi Hypoglycaemic and hypotensive effects of Globimetula cupulata (DC) Van Tieghem (Loranthaceae) aqueous leaf extract in rats
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Cardiovasc J S Afr 18:9-15. 2007
    ..This therefore lends pharmacological support to the folkloric, ethnomedical uses of the plant in the management and/ or control of diabetes mellitus and hypertension among the Yoruba-speaking people of western Nigeria...
  29. ncbi Analgesic, antiinflammatory and antidiabetic properties of Harpagophytum procumbens DC (Pedaliaceae) secondary root aqueous extract
    Ismail M Mahomed
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 18:982-9. 2004
    ....
  30. ncbi Hypoglycemic effect of Hypoxis hemerocallidea corm (African potato) aqueous extract in rats
    I M Mahomed
    Department of Pharmacology, Faculty of Health Sciences, University of Durban Westville, Durban 4000, South Africa
    Methods Find Exp Clin Pharmacol 25:617-23. 2003
    ....
  31. ncbi Effects of Ficus thonningii (Blume) [Morarceae] stem-bark ethanolic extract on blood glucose, cardiovascular and kidney functions of rats, and on kidney cell lines of the proximal (LLC-PK1) and distal tubules (MDBK)
    C T Musabayane
    Discipline of Human Physiology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Ren Fail 29:389-97. 2007
    ..Our experimental findings suggest that FTE possesses reno- and cardio-protective effects in diabetes mellitus...
  32. ncbi Cardiovascular effects of Persea americana Mill (Lauraceae) (avocado) aqueous leaf extract in experimental animals
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Cardiovasc J Afr 18:69-76. 2007
    ..However, the findings of this study tend to suggest that P americana leaf could be used as a natural supplementary remedy in essential hypertension and certain cases of cardiac dysfunctions in some rural Africa communities...
  33. ncbi Hypoglycemic effect of Sclerocarya birrea [(A. Rich.) Hochst.] [Anacardiaceae] stem-bark aqueous extract in rats
    J A O Ojewole
    Department of Pharmacology, University of Durban Westville, Durban, South Africa
    Phytomedicine 10:675-81. 2003
    ....
  34. ncbi Some in vitro and in vivo cardiovascular effects of Hypoxis hemerocallidea Fisch & CA Mey (Hypoxidaceae) corm (African potato) aqueous extract in experimental animal models
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Cardiovasc J S Afr 17:166-71. 2006
    ....
  35. ncbi Antiinflammatory properties of Hypoxis hemerocallidea corm (African potato) extracts in rats
    J A O Ojewole
    Department of Pharmacology, University of Durban Westville, Durban, South Africa
    Methods Find Exp Clin Pharmacol 24:685-7. 2002
    ..However, the two extracts of African potato examined in this study were found to be less potent than acetyl salicylic acid (ASA) as an antiinflammatory agent...
  36. ncbi Evaluation of the anti-inflammatory properties of Sclerocarya birrea (A. Rich.) Hochst. (family: Anacardiaceae) stem-bark extracts in rats
    John A O Ojewole
    Department of Pharmacology, University of Durban Westville, Private Bag X54001, Durban, 4000, South Africa
    J Ethnopharmacol 85:217-20. 2003
    ....
  37. ncbi Hypoglycaemic and hypotensive effects of Harpephyllum caffrum Bernh ex CF Krauss (Anacardiaceae) stem-bark aqueous extract in rats
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Cardiovasc J S Afr 17:67-72. 2006
    ....
  38. ncbi Potentiation of the antiinflammatory effect of Anacardium occidentale (Linn.) stem-bark aqueous extract by grapefruit juice
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of Durban Westville, Durban, South Africa
    Methods Find Exp Clin Pharmacol 26:183-8. 2004
    ....
  39. doi Grapefruit juice improves glycemic control but exacerbates metformin-induced lactic acidosis in non-diabetic rats
    P M O Owira
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 31:563-70. 2009
    ..0122; r(2) = 0.9080) and GFJ-treated test rats (P = 0.0005; r(2) = 0.9893). Although GFJ may be beneficial to diabetic patients, it may exacerbate lactic acidosis in diabetic patients taking metformin concurrently...
  40. ncbi Studies on the antiplasmodial properties of some South African medicinal plants used as antimalarial remedies in Zulu folk medicine
    N Nundkumar
    Department of Biochemistry, Faculty of Science, University of Durban Westville, Durban, South Africa
    Methods Find Exp Clin Pharmacol 24:397-401. 2002
    ..Phytochemical analysis of these two active plant extracts revealed the presence of anthraquinones, flavonoids, seccoirridoids and terpenoids...
  41. ncbi Effects of oral administration of some herbal extracts on food consumption and blood glucose levels in normal and streptozotocin-treated diabetic rats
    C T Musabayane
    Department of Human Physiology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Methods Find Exp Clin Pharmacol 28:223-8. 2006
    ..These findings merit long-term investigation...
  42. ncbi Effects of Hypoxis hemerocallidea (Fisch. & C.A. Mey.) [Hypoxidaceae] corm (African Potato) aqueous extract on renal electrolyte and fluid handling in the rat
    C T Musabayane
    Department of Human Physiology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Ren Fail 27:763-70. 2005
    ..02 mL x min (-1)) and increased plasma creatinine concentration (55 +/- 3 micromol x L(-1) vs. 68 +/-6 micromol x L(-1)). The results from this study suggest that the H. hemerocallidea corm aqueous extract may impair kidney function...
  43. pmc Cardiovascular effects of Ekebergia capensis Sparrm (Meliaceae) ethanolic leaf extract in experimental animal paradigms
    David R Kamadyaapa
    Department of Human Physiology, School of Medical Sciences, University of KwaZulu Natal, Durban, South Africa
    Cardiovasc J Afr 20:162-7, 169. 2009
    ..These observations suggest that the hypotensive effect of EKE was in part mediated via modulation of total peripheral resistance of the vascular smooth muscles...
  44. ncbi Hypoglycemic effect of methanolic extract of Musa paradisiaca (Musaceae) green fruits in normal and diabetic mice
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of Durban Westville, Durban, South Africa
    Methods Find Exp Clin Pharmacol 25:453-6. 2003
    ....
  45. ncbi Laboratory evaluation of the hypoglycemic effect of Anacardium occidentale Linn (Anacardiaceae) stem-bark extracts in rats
    J A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of Durban Westville, Durban, South Africa
    Methods Find Exp Clin Pharmacol 25:199-204. 2003
    ....
  46. ncbi Vasorelaxant and hypotensive effects of Sclerocarya birrea (A Rich) Hochst (Anacardiaceae) stem bark aqueous extract in rats
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Cardiovasc J S Afr 17:117-23. 2006
    ....
  47. ncbi Hypoglycaemic and hypotensive effects of Momordica charantia Linn (Cucurbitaceae) whole-plant aqueous extract in rats
    John A O Ojewole
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Cardiovasc J S Afr 17:227-32. 2006
    ....
  48. ncbi Anticonvulsant activity of Harpagophytum procumbens DC [Pedaliaceae] secondary root aqueous extract in mice
    Ismail M Mahomed
    Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Brain Res Bull 69:57-62. 2006
    ....
  49. ncbi Effects of Syzygium cordatum (Hochst.) [Myrtaceae] leaf extract on plasma glucose and hepatic glycogen in streptozotocin-induced diabetic rats
    C T Musabayane
    Department of Human Physiology and Physiological Chemistry, School of Medical Sciences, University of KwaZulu Natal, Westville Campus, Private Bag X54001, Durban 4000, South Africa
    J Ethnopharmacol 97:485-90. 2005
    ..The possible mechanism(s) involved in the short-term hypoglycaemic effect of the extract could not be established by the current study...
  50. ncbi Diabetes mellitus and responses of the urinary bladder to acetylcholine: an in vitro study
    Abdon M Nsabimana
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    J Smooth Muscle Res 44:143-50. 2008
    ..The magnitude and/or intensity of the diabetic bladder enhanced contractile responses to ACh continued to increase as the diabetic state of the animals progressed...
  51. ncbi Biphasic effect of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract on rat isolated vascular smooth muscles
    Witness D H Chiwororo
    Department of Pharmacology, University of KwaZulu Natal, Durban, South Africa
    J Smooth Muscle Res 44:217-29. 2008
    ..Taken together, the findings of this study indicate that PGE possesses a biphasic effect on rat isolated vascular smooth muscles...
  52. doi 'African potato' (Hypoxis hemerocallidea corm): a plant-medicine for modern and 21st century diseases of mankind? - a review
    Peter M O Owira
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, South Africa
    Phytother Res 23:147-52. 2009
    ..However, more laboratory and clinical studies are required to clarify these observations, and to isolate, purify and characterize the active chemical constituents responsible for the herb's pharmaco-therapeutic effects...
  53. ncbi Cardiovascular effects of Helichrysum ceres S Moore [Asteraceae] ethanolic leaf extract in some experimental animal paradigms
    Cephas T Musabayane
    Department of Human Physiology, School of Medical Sciences, University of KwaZulu Natal, Durban
    Cardiovasc J Afr 19:246-53. 2008
    ..The observed cardiovascular effects of HCE partly support the basis for its use in the management of high blood pressure in folkloric medicine...
  54. ncbi Spasmolytic effect of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract on rat isolated uterine horns
    Witness D H Chiwororo
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    J Smooth Muscle Res 45:31-8. 2009
    ..The spasmolytic effect of PGE observed in the present study lends pharmacological support to the traditional use of ;guava' leaves in the management, control and/or treatment of primary dysmenorrhoea in some rural African communities...
  55. ncbi Evaluation of the antidysrhythmic effects of delta- and kappa-opioid receptor agonists and antagonists on calcium chloride-, adrenaline- and ischemia/reperfusion-induced arrhythmias in rats
    A Valtchanova-Matchouganska
    Department of Pharmacology, Faculty of Health Sciences, University of Durban Westville, Durban, South Africa
    Methods Find Exp Clin Pharmacol 26:31-8. 2004
    ....
  56. ncbi Uterotonic effect of Harpagophytum procumbens DC (Pedaliaceae) secondary root aqueous extract on rat isolated uterine horns
    Ismail M Mahomed
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban 4000, South Africa
    J Smooth Muscle Res 45:231-9. 2009
    ..These findings lend pharmacological credence to the suggested folkloric obstetric uses of the plant's secondary root for induction and/or acceleration of labour, as well as for expelling retained placentas in pregnant women...
  57. ncbi Therapeutic claims of African potato: Fact or fiction?
    John A O Ojewole
    Cardiovasc J S Afr 17:225-6. 2006