Research Topics
| Keren MiddelkoopSummaryAffiliation: University of Cape Town Country: South Africa Publications
| Collaborators
|
Detail Information
Publications
Antiretroviral therapy and TB notification rates in a high HIV prevalence South African communityKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
J Acquir Immune Defic Syndr 56:263-9. 2011..Antiretroviral therapy (ART) has been proposed as an intervention for reducing tuberculosis (TB) burdens in areas with high HIV prevalence. However, little data is available on the impact of ART on population-level TB...
Antiretroviral program associated with reduction in untreated prevalent tuberculosis in a South African townshipKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
Am J Respir Crit Care Med 182:1080-5. 2010..Prevalent untreated TB is the main source of transmission. In settings with large burdens of human immunodeficiency virus (HIV) and TB, highly active antiretroviral therapy (HAART) may contribute to TB control...- Indoor social networks in a South African township: potential contribution of location to tuberculosis transmissionRobin Wood
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
PLoS ONE 7:e39246. 2012..We therefore quantified time spent and contacts met in indoor locations and public transport by residents of a South African township with a very high TB burden... - Changing patterns in HIV/AIDS stigma and uptake of voluntary counselling and testing services: the results of two consecutive community surveys conducted in the Western Cape, South AfricaSumaya Mall
Department of Psychology, University of Stellenbosch, Cape Town, South Africa
AIDS Care 25:194-201. 2013..Given the role of HIV/AIDS-associated stigma in influencing choices to access HIV testing, and the benefits associated with HIV testing, interventions to reduce stigma in communities affected by this disease should be encouraged... - Social mixing patterns within a South African township community: implications for respiratory disease transmission and controlSimon P Johnstone-Robertson
Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Western Cape, South Africa
Am J Epidemiol 174:1246-55. 2011..High numbers of indoor contacts and intergenerational mixing in households and transport may contribute to exceptionally high rates of tuberculosis transmission reported in the community... - Rates of tuberculosis transmission to children and adolescents in a community with a high prevalence of HIV infection among adultsKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, School of Public Health and Family Medicine, University of Cape Town, Mowbray, Cape Town, South Africa
Clin Infect Dis 47:349-55. 2008.... - Force of tuberculosis infection among adolescents in a high HIV and TB prevalence community: a cross-sectional observation studyKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
BMC Infect Dis 11:156. 2011..However, there are little data assessing incidence of TB infection in adolescents in these settings... - Childhood tuberculosis infection and disease: a spatial and temporal transmission analysis in a South African townshipKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Department of Medicine, University of Cape Town
S Afr Med J 99:738-43. 2009..While adult TB results from both recent and past infection, childhood TB results from recent infection and reflects ongoing transmission despite current TB control strategies... - Adolescent and adult participation in an HIV vaccine trial preparedness cohort in South AfricaKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
J Adolesc Health 43:8-14. 2008..We analyzed adult and adolescent data from a cohort study conducted to assess the feasibility of involving adolescents and adults in HIV vaccine-related studies... - Burden of new and recurrent tuberculosis in a major South African city stratified by age and HIV-statusRobin Wood
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
PLoS ONE 6:e25098. 2011.... - Molecular epidemiology of Mycobacterium tuberculosis in a South African community with high HIV prevalenceKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Cape Town, South Africa
J Infect Dis 200:1207-11. 2009..The strong association between W-Beijing and HIV infection may have important implications for tuberculosis control... - Socio-behaviour challenges to phase III HIV vaccine trials in Sub-Saharan AfricaJoalida Smit
MRC Unit for Anxiety and Stress Disorders, University of Stellenbosch, Cape Town, South Africa
Afr Health Sci 5:198-206. 2005..There is a need for a review of the literature to help focus such research efforts in Sub-Saharan Africa... - Sexual health, HIV risk, and retention in an adolescent HIV-prevention trial preparatory cohortHeather B Jaspan
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
J Adolesc Health 49:42-6. 2011..Although adolescents are at high risk for human immunodeficiency virus (HIV) infection, they have not been, included in HIV vaccine trials... - Lipoarabinomannan in urine during tuberculosis treatment: association with host and pathogen factors and mycobacteriuriaRobin Wood
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town Faculty of Health Sciences, Cape Town, South Africa
BMC Infect Dis 12:47. 2012..However, the LAM-ELISA assay has demonstrated variable sensitivity in diagnosing TB in diverse clinical populations. We therefore explored pathogen and host factors potentially impacting LAM detection... 
Low acceptability of medical male circumcision as an HIV/AIDS prevention intervention within a South African community that practises traditional circumcisionDaniella Mark
Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town
S Afr Med J 102:571-3. 2012..The acceptability of circumcision as a biomedical intervention mirroring an ingrained cultural practice, as well as the age and extent of the procedure, are poorly understood...- Impact of HIV infection on the epidemiology of tuberculosis in a peri-urban community in South Africa: the need for age-specific interventionsStephen D Lawn
Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
Clin Infect Dis 42:1040-7. 2006..Evaluation of additional control interventions requires detailed understanding of the epidemiological relationship between these diseases at the community level... - Tuberculosis transmission to young children in a South African community: modeling household and community infection risksRobin Wood
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Faculty of Health Sciences, Cape Town, South Africa
Clin Infect Dis 51:401-8. 2010..A model was used to explore the interactions between prevalence of adult tuberculosis infection, adult-to-child contacts, and household ventilation, which could result in such a high annual risk of tuberculosis infection... - Design and evaluation of a drama-based intervention to promote voluntary counseling and HIV testing in a South African communityKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
Sex Transm Dis 33:524-6. 2006..0001). CONCLUSION: A structured, community-based education program based on drama can lead to substantial increases in the demand for VCT services in resource-limited settings...