Research Topics
| Neil A MartinsonSummaryAffiliation: University of the Witwatersrand/Medical Research Council Country: South Africa Publications
| Collaborators
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Detail Information
Publications
Combining PMTCT with active case finding for tuberculosisPaula B N Kali
Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
J Acquir Immune Defic Syndr 42:379-81. 2006..We conclude that rates of TB in HIV-infected pregnant women are high, and screening for TB during routine antenatal care should be implemented in high HIV-prevalence settings...- HAART and risk of tuberculosis in HIV-infected South African children: a multi-site retrospective cohortNeil A Martinson
Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
Int J Tuberc Lung Dis 13:862-7. 2009..Four human immunodeficiency virus (HIV) clinics located at South African tertiary hospitals... - High rates of HIV in surgical patients in Soweto, South Africa: impact on resource utilisation and recommendations for HIV testingNeil A Martinson
Perinatal HIV Research Unit, University of Witwatersrand, Johannesburg, South Africa
Trans R Soc Trop Med Hyg 101:176-82. 2007..WHO clinical staging of HIV should include anal sepsis as an indicator of advanced HIV disease... - Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapineNeil A Martinson
Johns Hopkins University Center for Tuberculosis Research, Baltimore, MD, USA
J Acquir Immune Defic Syndr 44:148-53. 2007..Exposure to sd-NVP selects for resistance mutations, however. We longitudinally assessed these mutations in HIV-1-infected infants from Soweto and Durban, South Africa... - Transmission rates in consecutive pregnancies exposed to single-dose nevirapine in Soweto, South Africa and Abidjan, Côte d'IvoireNeil A Martinson
School of Medicine, Johns Hopkins University, Baltimore, MD, USA
J Acquir Immune Defic Syndr 45:206-9. 2007..Because sdNVP selects resistance in a high percentage of women, we compared the effectiveness of sdNVP in preventing peripartum MTCT in successive pregnancies... 
New regimens to prevent tuberculosis in adults with HIV infectionNeil A Martinson
Center for Tuberculosis Research and Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
N Engl J Med 365:11-20. 2011..We evaluated three new regimens for latent tuberculosis that may be more potent and durable than standard isoniazid treatment...
Women exposed to single-dose nevirapine in successive pregnancies: effectiveness and nonnucleoside reverse transcriptase inhibitor resistanceNeil A Martinson
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
AIDS 23:809-16. 2009..To assess the impact of prior exposure to single-dose nevirapine (sdNVP) on mother-to-child transmission and genotypic resistance in HIV-infected women...- Isoniazid preventive therapy, HAART and tuberculosis risk in HIV-infected adults in South Africa: a prospective cohortJonathan E Golub
Johns Hopkins University, School of Medicine, 1550 Orleans St, 1M 07 Baltimore, MD 21231, USA
AIDS 23:631-6. 2009..There is less information on the combined effect of IPT and HAART. We assessed the effect of IPT, HAART or both IPT and HAART on tuberculosis incidence in HIV-infected adults in South Africa... - Body mass index and risk of tuberculosis and deathColleen F Hanrahan
Johns Hopkins Bloomberg School of Public Heath, Baltimore, Maryland, USA
AIDS 24:1501-8. 2010..We examined the effect of BMI on all-cause mortality and TB incidence among a cohort of HIV-infected adults in Soweto, South Africa... - Short-course Combivir after single-dose nevirapine reduces but does not eliminate the emergence of nevirapine resistance in womenSarah Palmer
HIV Drug Resistance Program, NCI, NIH, Frederick, MD, USA
Antivir Ther 17:327-36. 2012..To detect NVP resistance with greater sensitivity, we analysed TOPS samples by allele-specific real-time PCR (ASP)... - Efficacy of short-course AZT plus 3TC to reduce nevirapine resistance in the prevention of mother-to-child HIV transmission: a randomized clinical trialJames A McIntyre
Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
PLoS Med 6:e1000172. 2009.... - Progression and regression of premalignant cervical lesions in HIV-infected women from Soweto: a prospective cohortTanvier Omar
Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg, South Africa
AIDS 25:87-94. 2011..To ascertain progression and regression of cervical dysplasia in HIV-infected women in Soweto... - Community-based targeted case finding for tuberculosis and HIV in household contacts of patients with tuberculosis in South AfricaAdrienne E Shapiro
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21231, USA
Am J Respir Crit Care Med 185:1110-6. 2012..South Africa has a high prevalence of tuberculosis (TB) and HIV-coinfected adults in whom TB is often diagnosed late in the course of disease... - Predictors of persistent cytologic abnormalities after treatment of cervical intraepithelial neoplasia in Soweto, South Africa: a cohort study in a HIV high prevalence populationYasmin Adam
Department of Obstetrics and Gynaecology, Chris Hani Baragwanath Hospital, Johannesburg, South Africa
BMC Cancer 8:211. 2008..We investigated clinical predictors of persistent cytological abnormalities in women who had had a large loop excision of the transformation zone (LLETZ)... - Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosisMaunank Shah
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Clin Microbiol 48:2972-4. 2010..Patients with disseminated TB and/or advanced HIV are target populations for whom urine LAM detection may be particularly useful... - Causes of death on antiretroviral therapy: a post-mortem study from South AfricaEmily B Wong
WITS Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa
PLoS ONE 7:e47542. 2012..Mortality in the first months of antiretroviral therapy (ART) is a significant clinical problem in sub-Saharan Africa. To date, no post-mortem study has investigated the causes of mortality in these patients... - Diagnostic accuracy of a urine lipoarabinomannan test for tuberculosis in hospitalized patients in a High HIV prevalence settingMaunank Shah
Department of Medicine, Johns Hopkins University Center for Tuberculosis Research, Baltimore, MD 21231, USA
J Acquir Immune Defic Syndr 52:145-51. 2009..Effective tuberculosis (TB) control in HIV-prevalent settings is hindered by absence of accurate, rapid TB diagnostic tests. We evaluated the accuracy of a urine lipoarabinomannan (LAM) test for TB diagnosis in South Africa... - Causes of death in hospitalized adults with a premortem diagnosis of tuberculosis: an autopsy studyNeil A Martinson
Johns Hopkins University Center for TB Research, Baltimore, Maryland, USA
AIDS 21:2043-50. 2007..To ascertain the immediate and underlying causes of death in adults who died in hospital with a premortem diagnosis of tuberculosis... - Tuberculosis in Africa--combating an HIV-driven crisisRichard E Chaisson
Center for Tuberculosis Research at the Johns Hopkins University School of Medicine, Baltimore, USA
N Engl J Med 358:1089-92. 2008 - Linking the global positioning system (GPS) to a personal digital assistant (PDA) to support tuberculosis control in South Africa: a pilot studyBarry Dwolatzky
School of Electrical and Information Engineering, University of the Witwatersrand, PO Box 542 Wits 2050 Johannesburg, South Africa
Int J Health Geogr 5:34. 2006..Additionally, we assessed the feasibility of using aerial photographs to locate homes... - Active tuberculosis case-finding among pregnant women presenting to antenatal clinics in Soweto, South AfricaCeline R Gounder
Center for Tuberculosis Research, Johns Hopkins University, Baltimore, MD 21287, USA
J Acquir Immune Defic Syndr 57:e77-84. 2011..TB is a significant cause of maternal morbidity. Detection of TB during pregnancy could provide substantial benefits to women and their children... - Comparative costs of inpatient care for HIV-infected and uninfected children and adults in Soweto, South AfricaLeena S Thomas
School of Public Health, University of the Witwatersrand, and Gauteng Department of Health, Johannesburg, South Africa
J Acquir Immune Defic Syndr 46:410-6. 2007..HIV/AIDS creates a massive burden of care for health systems. A better understanding of the impact of HIV infection on health care utilization and costs may enable better use of limited resources... - Preferences for characteristics of antiretroviral therapy provision in Johannesburg, South Africa: results of a conjoint analysisMarjorie Opuni
Department of Population, Family and Reproductive Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
AIDS Behav 14:807-15. 2010..8 and 3.0% in the HIV patient and household samples, respectively. Cost as well as staff attitude, wait time, and clinic branding may constitute important barriers to ART uptake and adherence in resource-poor settings... - Condom avoidance and determinants of demand for male circumcision in Johannesburg, South AfricaJohn F P Bridges
Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Health Policy Plan 26:298-306. 2011..This said, male circumcision strategies should reinforce a range of HIV prevention strategies, including condom use, as we find evidence that whites may view circumcision as a means to avoid condom use... - Designing family-centered male circumcision services: a conjoint analysis approachJohn F P Bridges
Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Patient 5:101-11. 2012..For many potential clients, mothers and/or fathers will play an important role in the decision to be circumcised, and hence services will need to be designed with the preferences of mothers, fathers, and sons in mind... - Male circumcision for HIV prevention: developments from sub-Saharan AfricaGuy de Bruyn
Perinatal HIV Research Unit, New Nurses Home, Chris Hani Baragwanath Hospital, Chris Hani Road, Johannesburg, South Africa
Expert Rev Anti Infect Ther 8:23-31. 2010..This perspective reviews recent research findings and provides a summary of progress in various countries... - Hepatitis B virus infection in human immunodeficiency virus infected southern African adults: occult or overt--that is the questionTrevor G Bell
Hepatitis Virus Diversity Research Programme, Department of Internal Medicine, University of the Witwatersrand, Johannesburg, South Africa
PLoS ONE 7:e45750. 2012..Detection of HBsAg(-ve) HBV DNA(+ve) subjects is advisable considering they were clinically indistinguishable from HBsAg(+ve) HBV DNA(+ve) individuals and should not be overlooked, especially if lamivudine is included in the ART... - Optimizing treatment for HIV-infected South African women exposed to single-dose nevirapine: balancing efficacy and costCharles B Holmes
Divisions of Infectious Disease and General Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
Clin Infect Dis 42:1772-80. 2006..Our objectives were to project the tradeoffs regarding life expectancy, cost, and cost-effectiveness of these ART regimens for NVP-exposed, HIV-infected women in South Africa... - Scaling up antiretroviral therapy in South Africa: the impact of speed on survivalRochelle P Walensky
The Divisions of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
J Infect Dis 197:1324-32. 2008..Only 33% of eligible human immunodeficiency virus (HIV)-infected patients in South Africa receive antiretroviral therapy (ART). We sought to estimate the impact of alternative ART scale-up scenarios on patient outcomes from 2007-2012...