Neil A Martinson

Summary

Affiliation: University of the Witwatersrand/Medical Research Council
Country: South Africa

Publications

  1. ncbi Combining PMTCT with active case finding for tuberculosis
    Paula B N Kali
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 42:379-81. 2006
  2. ncbi HAART and risk of tuberculosis in HIV-infected South African children: a multi-site retrospective cohort
    Neil A Martinson
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    Int J Tuberc Lung Dis 13:862-7. 2009
  3. ncbi High rates of HIV in surgical patients in Soweto, South Africa: impact on resource utilisation and recommendations for HIV testing
    Neil A Martinson
    Perinatal HIV Research Unit, University of Witwatersrand, Johannesburg, South Africa
    Trans R Soc Trop Med Hyg 101:176-82. 2007
  4. ncbi Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine
    Neil A Martinson
    Johns Hopkins University Center for Tuberculosis Research, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 44:148-53. 2007
  5. ncbi Transmission rates in consecutive pregnancies exposed to single-dose nevirapine in Soweto, South Africa and Abidjan, Côte d'Ivoire
    Neil A Martinson
    School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 45:206-9. 2007
  6. doi Women exposed to single-dose nevirapine in successive pregnancies: effectiveness and nonnucleoside reverse transcriptase inhibitor resistance
    Neil A Martinson
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    AIDS 23:809-16. 2009
  7. pmc New regimens to prevent tuberculosis in adults with HIV infection
    Neil A Martinson
    Center for Tuberculosis Research and Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    N Engl J Med 365:11-20. 2011
  8. pmc Isoniazid preventive therapy, HAART and tuberculosis risk in HIV-infected adults in South Africa: a prospective cohort
    Jonathan E Golub
    Johns Hopkins University, School of Medicine, 1550 Orleans St, 1M 07 Baltimore, MD 21231, USA
    AIDS 23:631-6. 2009
  9. pmc Body mass index and risk of tuberculosis and death
    Colleen F Hanrahan
    Johns Hopkins Bloomberg School of Public Heath, Baltimore, Maryland, USA
    AIDS 24:1501-8. 2010
  10. pmc Efficacy of short-course AZT plus 3TC to reduce nevirapine resistance in the prevention of mother-to-child HIV transmission: a randomized clinical trial
    James A McIntyre
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    PLoS Med 6:e1000172. 2009

Detail Information

Publications32

  1. ncbi Combining PMTCT with active case finding for tuberculosis
    Paula B N Kali
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 42:379-81. 2006
    ..We conclude that rates of TB in HIV-infected pregnant women are high, and screening for TB during routine antenatal care should be implemented in high HIV-prevalence settings...
  2. ncbi HAART and risk of tuberculosis in HIV-infected South African children: a multi-site retrospective cohort
    Neil A Martinson
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    Int J Tuberc Lung Dis 13:862-7. 2009
    ..Four human immunodeficiency virus (HIV) clinics located at South African tertiary hospitals...
  3. ncbi High rates of HIV in surgical patients in Soweto, South Africa: impact on resource utilisation and recommendations for HIV testing
    Neil A Martinson
    Perinatal HIV Research Unit, University of Witwatersrand, Johannesburg, South Africa
    Trans R Soc Trop Med Hyg 101:176-82. 2007
    ..WHO clinical staging of HIV should include anal sepsis as an indicator of advanced HIV disease...
  4. ncbi Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine
    Neil A Martinson
    Johns Hopkins University Center for Tuberculosis Research, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 44:148-53. 2007
    ..Exposure to sd-NVP selects for resistance mutations, however. We longitudinally assessed these mutations in HIV-1-infected infants from Soweto and Durban, South Africa...
  5. ncbi Transmission rates in consecutive pregnancies exposed to single-dose nevirapine in Soweto, South Africa and Abidjan, Côte d'Ivoire
    Neil A Martinson
    School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 45:206-9. 2007
    ..Because sdNVP selects resistance in a high percentage of women, we compared the effectiveness of sdNVP in preventing peripartum MTCT in successive pregnancies...
  6. doi Women exposed to single-dose nevirapine in successive pregnancies: effectiveness and nonnucleoside reverse transcriptase inhibitor resistance
    Neil A Martinson
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    AIDS 23:809-16. 2009
    ..To assess the impact of prior exposure to single-dose nevirapine (sdNVP) on mother-to-child transmission and genotypic resistance in HIV-infected women...
  7. pmc New regimens to prevent tuberculosis in adults with HIV infection
    Neil A Martinson
    Center for Tuberculosis Research and Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    N Engl J Med 365:11-20. 2011
    ..We evaluated three new regimens for latent tuberculosis that may be more potent and durable than standard isoniazid treatment...
  8. pmc Isoniazid preventive therapy, HAART and tuberculosis risk in HIV-infected adults in South Africa: a prospective cohort
    Jonathan E Golub
    Johns Hopkins University, School of Medicine, 1550 Orleans St, 1M 07 Baltimore, MD 21231, USA
    AIDS 23:631-6. 2009
    ..There is less information on the combined effect of IPT and HAART. We assessed the effect of IPT, HAART or both IPT and HAART on tuberculosis incidence in HIV-infected adults in South Africa...
  9. pmc Body mass index and risk of tuberculosis and death
    Colleen F Hanrahan
    Johns Hopkins Bloomberg School of Public Heath, Baltimore, Maryland, USA
    AIDS 24:1501-8. 2010
    ..We examined the effect of BMI on all-cause mortality and TB incidence among a cohort of HIV-infected adults in Soweto, South Africa...
  10. pmc Efficacy of short-course AZT plus 3TC to reduce nevirapine resistance in the prevention of mother-to-child HIV transmission: a randomized clinical trial
    James A McIntyre
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    PLoS Med 6:e1000172. 2009
    ....
  11. doi Short-course Combivir after single-dose nevirapine reduces but does not eliminate the emergence of nevirapine resistance in women
    Sarah Palmer
    HIV Drug Resistance Program, NCI, NIH, Frederick, MD, USA
    Antivir Ther 17:327-36. 2012
    ..To detect NVP resistance with greater sensitivity, we analysed TOPS samples by allele-specific real-time PCR (ASP)...
  12. pmc Progression and regression of premalignant cervical lesions in HIV-infected women from Soweto: a prospective cohort
    Tanvier Omar
    Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 25:87-94. 2011
    ..To ascertain progression and regression of cervical dysplasia in HIV-infected women in Soweto...
  13. doi Community-based targeted case finding for tuberculosis and HIV in household contacts of patients with tuberculosis in South Africa
    Adrienne E Shapiro
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21231, USA
    Am J Respir Crit Care Med 185:1110-6. 2012
    ..South Africa has a high prevalence of tuberculosis (TB) and HIV-coinfected adults in whom TB is often diagnosed late in the course of disease...
  14. pmc Predictors of persistent cytologic abnormalities after treatment of cervical intraepithelial neoplasia in Soweto, South Africa: a cohort study in a HIV high prevalence population
    Yasmin Adam
    Department of Obstetrics and Gynaecology, Chris Hani Baragwanath Hospital, Johannesburg, South Africa
    BMC Cancer 8:211. 2008
    ..We investigated clinical predictors of persistent cytological abnormalities in women who had had a large loop excision of the transformation zone (LLETZ)...
  15. pmc Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis
    Maunank Shah
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Clin Microbiol 48:2972-4. 2010
    ..Patients with disseminated TB and/or advanced HIV are target populations for whom urine LAM detection may be particularly useful...
  16. pmc CD4 and viral load dynamics in antiretroviral-naïve HIV-infected adults from Soweto, South Africa: a prospective cohort
    Neil A Martinson
    Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America Department of Science and Technology National Research Foundation Centre of Excellence for Biomedical TB Research, Johannesburg, South Africa
    PLoS ONE 9:e96369. 2014
    ..Our objective is to report CD4 decline and changes in viral load (VL) in a group of HIV-infected adults enrolled in a randomized trial of preventive treatment for TB in South Africa where clade C infection predominates...
  17. pmc Causes of death on antiretroviral therapy: a post-mortem study from South Africa
    Emily B Wong
    WITS Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 7:e47542. 2012
    ..Mortality in the first months of antiretroviral therapy (ART) is a significant clinical problem in sub-Saharan Africa. To date, no post-mortem study has investigated the causes of mortality in these patients...
  18. pmc Diagnostic accuracy of a urine lipoarabinomannan test for tuberculosis in hospitalized patients in a High HIV prevalence setting
    Maunank Shah
    Department of Medicine, Johns Hopkins University Center for Tuberculosis Research, Baltimore, MD 21231, USA
    J Acquir Immune Defic Syndr 52:145-51. 2009
    ..Effective tuberculosis (TB) control in HIV-prevalent settings is hindered by absence of accurate, rapid TB diagnostic tests. We evaluated the accuracy of a urine lipoarabinomannan (LAM) test for TB diagnosis in South Africa...
  19. ncbi Causes of death in hospitalized adults with a premortem diagnosis of tuberculosis: an autopsy study
    Neil A Martinson
    Johns Hopkins University Center for TB Research, Baltimore, Maryland, USA
    AIDS 21:2043-50. 2007
    ..To ascertain the immediate and underlying causes of death in adults who died in hospital with a premortem diagnosis of tuberculosis...
  20. doi Tuberculosis in Africa--combating an HIV-driven crisis
    Richard E Chaisson
    Center for Tuberculosis Research at the Johns Hopkins University School of Medicine, Baltimore, USA
    N Engl J Med 358:1089-92. 2008
  21. pmc Mortality associated with delays between clinic entry and ART initiation in resource-limited settings: results of a transition-state model
    Christopher J Hoffmann
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    J Acquir Immune Defic Syndr 63:105-11. 2013
    ..To estimate the mortality impact of delay in antiretroviral therapy (ART) initiation from the time of entry into care...
  22. pmc Linking the global positioning system (GPS) to a personal digital assistant (PDA) to support tuberculosis control in South Africa: a pilot study
    Barry Dwolatzky
    School of Electrical and Information Engineering, University of the Witwatersrand, PO Box 542 Wits 2050 Johannesburg, South Africa
    Int J Health Geogr 5:34. 2006
    ..Additionally, we assessed the feasibility of using aerial photographs to locate homes...
  23. ncbi Comparative costs of inpatient care for HIV-infected and uninfected children and adults in Soweto, South Africa
    Leena S Thomas
    School of Public Health, University of the Witwatersrand, and Gauteng Department of Health, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 46:410-6. 2007
    ..HIV/AIDS creates a massive burden of care for health systems. A better understanding of the impact of HIV infection on health care utilization and costs may enable better use of limited resources...
  24. pmc Active tuberculosis case-finding among pregnant women presenting to antenatal clinics in Soweto, South Africa
    Celine R Gounder
    Center for Tuberculosis Research, Johns Hopkins University, Baltimore, MD 21287, USA
    J Acquir Immune Defic Syndr 57:e77-84. 2011
    ..TB is a significant cause of maternal morbidity. Detection of TB during pregnancy could provide substantial benefits to women and their children...
  25. doi Condom avoidance and determinants of demand for male circumcision in Johannesburg, South Africa
    John F P Bridges
    Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Health Policy Plan 26:298-306. 2011
    ..This said, male circumcision strategies should reinforce a range of HIV prevention strategies, including condom use, as we find evidence that whites may view circumcision as a means to avoid condom use...
  26. ncbi Preferences for characteristics of antiretroviral therapy provision in Johannesburg, South Africa: results of a conjoint analysis
    Marjorie Opuni
    Department of Population, Family and Reproductive Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    AIDS Behav 14:807-15. 2010
    ..8 and 3.0% in the HIV patient and household samples, respectively. Cost as well as staff attitude, wait time, and clinic branding may constitute important barriers to ART uptake and adherence in resource-poor settings...
  27. ncbi Designing family-centered male circumcision services: a conjoint analysis approach
    John F P Bridges
    Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Patient 5:101-11. 2012
    ..For many potential clients, mothers and/or fathers will play an important role in the decision to be circumcised, and hence services will need to be designed with the preferences of mothers, fathers, and sons in mind...
  28. doi Male circumcision for HIV prevention: developments from sub-Saharan Africa
    Guy de Bruyn
    Perinatal HIV Research Unit, New Nurses Home, Chris Hani Baragwanath Hospital, Chris Hani Road, Johannesburg, South Africa
    Expert Rev Anti Infect Ther 8:23-31. 2010
    ..This perspective reviews recent research findings and provides a summary of progress in various countries...
  29. pmc Maternal hepatitis B and infant infection among pregnant women living with HIV in South Africa
    Christopher J Hoffmann
    Center for TB Research, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    J Int AIDS Soc 17:18871. 2014
    ..We describe maternal chronic hepatitis B (CHB) prevalence and infant infection during the first year of life within a cohort of women living with HIV...
  30. pmc Hepatitis B virus infection in human immunodeficiency virus infected southern African adults: occult or overt--that is the question
    Trevor G Bell
    Hepatitis Virus Diversity Research Programme, Department of Internal Medicine, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 7:e45750. 2012
    ..Detection of HBsAg(-ve) HBV DNA(+ve) subjects is advisable considering they were clinically indistinguishable from HBsAg(+ve) HBV DNA(+ve) individuals and should not be overlooked, especially if lamivudine is included in the ART...
  31. pmc Scaling up antiretroviral therapy in South Africa: the impact of speed on survival
    Rochelle P Walensky
    The Divisions of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Infect Dis 197:1324-32. 2008
    ..Only 33% of eligible human immunodeficiency virus (HIV)-infected patients in South Africa receive antiretroviral therapy (ART). We sought to estimate the impact of alternative ART scale-up scenarios on patient outcomes from 2007-2012...
  32. ncbi Optimizing treatment for HIV-infected South African women exposed to single-dose nevirapine: balancing efficacy and cost
    Charles B Holmes
    Divisions of Infectious Disease and General Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
    Clin Infect Dis 42:1772-80. 2006
    ..Our objectives were to project the tradeoffs regarding life expectancy, cost, and cost-effectiveness of these ART regimens for NVP-exposed, HIV-infected women in South Africa...