A I Louw

Summary

Affiliation: University of Pretoria
Country: South Africa

Publications

  1. pmc Heterologous expression of plasmodial proteins for structural studies and functional annotation
    Lyn Marie Birkholtz
    Department of Biochemistry, University of Pretoria, Pretoria, South Africa
    Malar J 7:197. 2008
  2. pmc Deletion mutagenesis of large areas in Plasmodium falciparum genes: a comparative study
    Marni Williams
    Department of Biochemistry, School of Biological Sciences, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa
    Malar J 6:64. 2007
  3. pmc Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels
    John V W Becker
    CSIR Biosciences, PO Box 395, Pretoria, 0001, South Africa
    BMC Genomics 11:235. 2010
  4. pmc MADIBA: a web server toolkit for biological interpretation of Plasmodium and plant gene clusters
    Philip J Law
    Bioinformatics and Computational Biology Unit, African Centre for Gene Technologies ACGT, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, 0002, South Africa
    BMC Genomics 9:105. 2008
  5. ncbi request reprint The influence of tick behavior, biotope and host specificity on concerted evolution of the platelet aggregation inhibitor savignygrin, from the soft tick Ornithodoros savignyi
    B J Mans
    Department of Biochemistry, University of Pretoria, Pretoria 0002, South Africa
    Insect Biochem Mol Biol 33:623-9. 2003

Collaborators

  • B J Mans
  • Lyn Marie Birkholtz
  • John V W Becker
  • Philip J Law
  • Marni Williams
  • Bridget G Crampton
  • Stoyan Stoychev
  • Dalu T Mancama
  • Shaun Reeksting
  • Linda Mtwisha
  • Anna C van Brummelen
  • Elizabeth J Morris
  • Gregory Blatch
  • Dave K Berger
  • Linda Stephens
  • Addmore Shonhai
  • Fourie Joubert
  • Lyndon Oldfield
  • Clotilde Claudel-Renard
  • Esmaré Human
  • Robyn Roth
  • Theresa L Coetzer
  • Zoleka Ngcete
  • Heinrich C Hoppe

Detail Information

Publications5

  1. pmc Heterologous expression of plasmodial proteins for structural studies and functional annotation
    Lyn Marie Birkholtz
    Department of Biochemistry, University of Pretoria, Pretoria, South Africa
    Malar J 7:197. 2008
    ..Here the status quo of heterologous production of plasmodial proteins is presented, constraints are highlighted and alternative strategies and hosts for functional expression and annotation of plasmodial proteins are reviewed...
  2. pmc Deletion mutagenesis of large areas in Plasmodium falciparum genes: a comparative study
    Marni Williams
    Department of Biochemistry, School of Biological Sciences, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa
    Malar J 6:64. 2007
    ..A comparative study of five widely used PCR-based mutagenesis methods identified a modified inverse PCR method as particularly suitable for the deletion of large areas (>100 bp) in malaria parasite genes...
  3. pmc Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels
    John V W Becker
    CSIR Biosciences, PO Box 395, Pretoria, 0001, South Africa
    BMC Genomics 11:235. 2010
    ..falciparum spermidine synthase (PfSpdSyn) were examined on a morphological, transcriptomic, proteomic and metabolic level...
  4. pmc MADIBA: a web server toolkit for biological interpretation of Plasmodium and plant gene clusters
    Philip J Law
    Bioinformatics and Computational Biology Unit, African Centre for Gene Technologies ACGT, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, 0002, South Africa
    BMC Genomics 9:105. 2008
    ..While many algorithms and software have been developed for analysing gene expression, the extraction of relevant information from experimental data is still a substantial challenge, requiring significant time and skill...
  5. ncbi request reprint The influence of tick behavior, biotope and host specificity on concerted evolution of the platelet aggregation inhibitor savignygrin, from the soft tick Ornithodoros savignyi
    B J Mans
    Department of Biochemistry, University of Pretoria, Pretoria 0002, South Africa
    Insect Biochem Mol Biol 33:623-9. 2003
    ..Our results suggest that environmental factors and host associations do play an important role in the evolution of anti-hemostatic components in ticks...