Leigh F Johnson

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. doi A review of mathematical models of HIV/AIDS interventions and their implications for policy
    Leigh F Johnson
    School of Public Health and Family Medicine, Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    Sex Transm Infect 87:629-34. 2011
  2. ncbi The effect of early initiation of antiretroviral treatment in infants on pediatric AIDS mortality in South Africa: a model-based analysis
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    Pediatr Infect Dis J 31:474-80. 2012
  3. pmc Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    PLoS Med 10:e1001418. 2013
  4. pmc The effect of changes in condom usage and antiretroviral treatment coverage on human immunodeficiency virus incidence in South Africa: a model-based analysis
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    J R Soc Interface 9:1544-54. 2012
  5. pmc The contribution of maternal HIV seroconversion during late pregnancy and breastfeeding to mother-to-child transmission of HIV
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 59:417-25. 2012
  6. doi The role of immunity in the epidemiology of gonorrhoea, chlamydial infection and trichomoniasis: insights from a mathematical model
    L F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa
    Epidemiol Infect 139:1875-83. 2011
  7. doi The effect of syndromic management interventions on the prevalence of sexually transmitted infections in South Africa
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa
    Sex Reprod Healthc 2:13-20. 2011
  8. pmc A Bayesian approach to uncertainty analysis of sexually transmitted infection models
    Leigh F Johnson
    Centre for Actuarial Research, University of Cape Town, Rondebosch, Cape Town, South Africa
    Sex Transm Infect 86:169-74. 2010
  9. ncbi The effect of educational attainment and other factors on HIV risk in South African women: results from antenatal surveillance, 2000-2005
    Leigh F Johnson
    Centre for Actuarial Research, University of Cape Town, South Africa
    AIDS 23:1583-8. 2009
  10. ncbi The effect of genital tract infections on HIV-1 shedding in the genital tract: a systematic review and meta-analysis
    Leigh F Johnson
    Centre for Actuarial Research, University of Cape Town, South Africa
    Sex Transm Dis 35:946-59. 2008

Detail Information

Publications20

  1. doi A review of mathematical models of HIV/AIDS interventions and their implications for policy
    Leigh F Johnson
    School of Public Health and Family Medicine, Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    Sex Transm Infect 87:629-34. 2011
    ..This review aims to summarise key messages emerging from mathematical models of HIV/AIDS interventions and identifies ways in which models can assist policy makers...
  2. ncbi The effect of early initiation of antiretroviral treatment in infants on pediatric AIDS mortality in South Africa: a model-based analysis
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    Pediatr Infect Dis J 31:474-80. 2012
    ..This study aims to assess the likely impact of this change in guideline in South Africa...
  3. pmc Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    PLoS Med 10:e1001418. 2013
    ..We aimed to estimate the life expectancy of patients starting ART in South Africa and compare it with that of HIV-negative adults...
  4. pmc The effect of changes in condom usage and antiretroviral treatment coverage on human immunodeficiency virus incidence in South Africa: a model-based analysis
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    J R Soc Interface 9:1544-54. 2012
    ..Both models also estimated a small reduction in incidence owing to antiretroviral treatment by 2008. Increased condom use therefore appears to be the most significant factor explaining the recent South African HIV incidence decline...
  5. pmc The contribution of maternal HIV seroconversion during late pregnancy and breastfeeding to mother-to-child transmission of HIV
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 59:417-25. 2012
    ....
  6. doi The role of immunity in the epidemiology of gonorrhoea, chlamydial infection and trichomoniasis: insights from a mathematical model
    L F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa
    Epidemiol Infect 139:1875-83. 2011
    ..Mathematical models that do not allow for immunity could therefore overestimate the effectiveness of STI interventions...
  7. doi The effect of syndromic management interventions on the prevalence of sexually transmitted infections in South Africa
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa
    Sex Reprod Healthc 2:13-20. 2011
    ..This study aims to determine the effect of syndromic management protocols that have been introduced in South Africa since 1994...
  8. pmc A Bayesian approach to uncertainty analysis of sexually transmitted infection models
    Leigh F Johnson
    Centre for Actuarial Research, University of Cape Town, Rondebosch, Cape Town, South Africa
    Sex Transm Infect 86:169-74. 2010
    ....
  9. ncbi The effect of educational attainment and other factors on HIV risk in South African women: results from antenatal surveillance, 2000-2005
    Leigh F Johnson
    Centre for Actuarial Research, University of Cape Town, South Africa
    AIDS 23:1583-8. 2009
    ..To assess the effect of educational attainment and other factors on the risk of HIV in pregnant South African women...
  10. ncbi The effect of genital tract infections on HIV-1 shedding in the genital tract: a systematic review and meta-analysis
    Leigh F Johnson
    Centre for Actuarial Research, University of Cape Town, South Africa
    Sex Transm Dis 35:946-59. 2008
    ..These infections are likely to be particularly important in promoting the sexual transmission and mother-to-child intrapartum transmission of HIV-1, and should therefore be the focus of HIV prevention strategies...
  11. ncbi The burden of disease attributable to sexually transmitted infections in South Africa in 2000
    Leigh Johnson
    Centre for Actuarial Research, University of Cape Town
    S Afr Med J 97:658-62. 2007
    ..To estimate the burden of disease attributable to sexually transmitted infections (STIs) in South Africa, to identify the factors contributing to this burden, and to review successes and failures in reducing this burden...
  12. ncbi HIV/AIDS vaccination in adolescents would be efficient and practical when vaccine supplies are limited
    Leigh F Johnson
    Centre for Actuarial Research, University of Cape Town, Private Bag, Rondebosch 7701, South Africa
    Vaccine 25:7502-9. 2007
    ....
  13. doi The impact of human immunodeficiency virus on human papillomavirus transmission in heterosexually active couples
    Zizipho Z A Mbulawa
    Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    J Infect 67:51-8. 2013
    ..This study investigated HPV transmission and the factors influencing it in heterosexually active couples in South Africa...
  14. pmc Gender differences in survival among adult patients starting antiretroviral therapy in South Africa: a multicentre cohort study
    Morna Cornell
    Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    PLoS Med 9:e1001304. 2012
    ..Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood. We examined the magnitude of and risk factors for gender differences in mortality on ART...
  15. ncbi The role of sexually transmitted infections in the evolution of the South African HIV epidemic
    Leigh F Johnson
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Anzio Road, Observatory, South Africa
    Trop Med Int Health 17:161-8. 2012
    ..To assess the extent to which sexually transmitted infections (STIs) have contributed to the spread of HIV in South Africa and to estimate the extent to which improvements in STI treatment have reduced HIV incidence...
  16. pmc Increased alpha-9 human papillomavirus species viral load in human immunodeficiency virus positive women
    Zizipho Z A Mbulawa
    Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory, 7925 Cape Town, South Africa
    BMC Infect Dis 14:51. 2014
    ..This study investigated the effect of human immunodeficiency virus (HIV) co-infection, HIV viral load and CD4 count on the HR-HPV viral load; and also investigated the predictors of cervical abnormalities...
  17. pmc Antiretroviral therapy and TB notification rates in a high HIV prevalence South African community
    Keren Middelkoop
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 56:263-9. 2011
    ..Antiretroviral therapy (ART) has been proposed as an intervention for reducing tuberculosis (TB) burdens in areas with high HIV prevalence. However, little data is available on the impact of ART on population-level TB...
  18. pmc Tracing of patients lost to follow-up and HIV transmission: mathematical modeling study based on 2 large ART programs in Malawi
    Janne Estill
    Institute of Social and Preventive Medicine ISPM, University of Bern, Bern, Switzerland The International Union Against Tuberculosis and Lung Disease, Paris, France Lighthouse Trust, Lilongwe, Malawi Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa Department of Infectious Diseases, University Hospital Bern, Bern, Switzerland Department of Infectious Diseases, University of Dakar, Dakar, Senegal International Training and Education Center for Health, University of Washington, Seattle, WA
    J Acquir Immune Defic Syndr 65:e179-86. 2014
    ..Treatment as prevention depends on retaining HIV-infected patients in care. We investigated the effect on HIV transmission of bringing patients lost to follow-up (LTFU) back into care...
  19. ncbi Influence of human immunodeficiency virus and CD4 count on the prevalence of human papillomavirus in heterosexual couples
    Zizipho Z A Mbulawa
    Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    J Gen Virol 91:3023-31. 2010
    ..In contrast, female genital HPV prevalence and HPV type-specific sharing were determined by their own HIV-positive status and not by that of their male partner...
  20. ncbi Steady growth in antiretroviral treatment provision by disease management and community treatment programmes
    Leigh F Johnson
    S Afr Med J 97:358-9. 2007