Research Topics
| Leigh F JohnsonSummaryAffiliation: University of Cape Town Country: South Africa Publications
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Detail Information
Publications
The effect of changes in condom usage and antiretroviral treatment coverage on human immunodeficiency virus incidence in South Africa: a model-based analysisLeigh F Johnson
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
J R Soc Interface 9:1544-54. 2012..Both models also estimated a small reduction in incidence owing to antiretroviral treatment by 2008. Increased condom use therefore appears to be the most significant factor explaining the recent South African HIV incidence decline...
The effect of early initiation of antiretroviral treatment in infants on pediatric AIDS mortality in South Africa: a model-based analysisLeigh F Johnson
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
Pediatr Infect Dis J 31:474-80. 2012..This study aims to assess the likely impact of this change in guideline in South Africa...
The contribution of maternal HIV seroconversion during late pregnancy and breastfeeding to mother-to-child transmission of HIVLeigh F Johnson
Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
J Acquir Immune Defic Syndr 59:417-25. 2012....
A review of mathematical models of HIV/AIDS interventions and their implications for policyLeigh F Johnson
School of Public Health and Family Medicine, Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
Sex Transm Infect 87:629-34. 2011..This review aims to summarise key messages emerging from mathematical models of HIV/AIDS interventions and identifies ways in which models can assist policy makers...
The effect of syndromic management interventions on the prevalence of sexually transmitted infections in South AfricaLeigh F Johnson
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa
Sex Reprod Healthc 2:13-20. 2011..This study aims to determine the effect of syndromic management protocols that have been introduced in South Africa since 1994...
The role of immunity in the epidemiology of gonorrhoea, chlamydial infection and trichomoniasis: insights from a mathematical modelL F Johnson
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa
Epidemiol Infect 139:1875-83. 2011..Mathematical models that do not allow for immunity could therefore overestimate the effectiveness of STI interventions...
A Bayesian approach to uncertainty analysis of sexually transmitted infection modelsLeigh F Johnson
Centre for Actuarial Research, University of Cape Town, Rondebosch, Cape Town, South Africa
Sex Transm Infect 86:169-74. 2010....
The effect of educational attainment and other factors on HIV risk in South African women: results from antenatal surveillance, 2000-2005Leigh F Johnson
Centre for Actuarial Research, University of Cape Town, South Africa
AIDS 23:1583-8. 2009..To assess the effect of educational attainment and other factors on the risk of HIV in pregnant South African women...
The effect of genital tract infections on HIV-1 shedding in the genital tract: a systematic review and meta-analysisLeigh F Johnson
Centre for Actuarial Research, University of Cape Town, South Africa
Sex Transm Dis 35:946-59. 2008..These infections are likely to be particularly important in promoting the sexual transmission and mother-to-child intrapartum transmission of HIV-1, and should therefore be the focus of HIV prevention strategies...
The burden of disease attributable to sexually transmitted infections in South Africa in 2000Leigh Johnson
Centre for Actuarial Research, University of Cape Town
S Afr Med J 97:658-62. 2007..To estimate the burden of disease attributable to sexually transmitted infections (STIs) in South Africa, to identify the factors contributing to this burden, and to review successes and failures in reducing this burden...
HIV/AIDS vaccination in adolescents would be efficient and practical when vaccine supplies are limitedLeigh F Johnson
Centre for Actuarial Research, University of Cape Town, Private Bag, Rondebosch 7701, South Africa
Vaccine 25:7502-9. 2007....
The role of sexually transmitted infections in the evolution of the South African HIV epidemicLeigh F Johnson
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Anzio Road, Observatory, South Africa
Trop Med Int Health 17:161-8. 2012..To assess the extent to which sexually transmitted infections (STIs) have contributed to the spread of HIV in South Africa and to estimate the extent to which improvements in STI treatment have reduced HIV incidence...
Life expectancies of South african adults starting antiretroviral treatment: collaborative analysis of cohort studiesLeigh F Johnson
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
PLoS Med 10:e1001418. 2013..We aimed to estimate the life expectancy of patients starting ART in South Africa and compare it with that of HIV-negative adults...
Gender differences in survival among adult patients starting antiretroviral therapy in South Africa: a multicentre cohort studyMorna Cornell
Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
PLoS Med 9:e1001304. 2012..Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood. We examined the magnitude of and risk factors for gender differences in mortality on ART...
Antiretroviral therapy and TB notification rates in a high HIV prevalence South African communityKeren Middelkoop
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
J Acquir Immune Defic Syndr 56:263-9. 2011..Antiretroviral therapy (ART) has been proposed as an intervention for reducing tuberculosis (TB) burdens in areas with high HIV prevalence. However, little data is available on the impact of ART on population-level TB...
Influence of human immunodeficiency virus and CD4 count on the prevalence of human papillomavirus in heterosexual couplesZizipho Z A Mbulawa
Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
J Gen Virol 91:3023-31. 2010..In contrast, female genital HPV prevalence and HPV type-specific sharing were determined by their own HIV-positive status and not by that of their male partner...
Steady growth in antiretroviral treatment provision by disease management and community treatment programmesLeigh F Johnson
S Afr Med J 97:358-9. 2007
