J M Heckmann

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. ncbi request reprint The characteristics of juvenile myasthenia gravis among South Africans
    Jeannine M Heckmann
    Division of Neurology, Department of Medicine, Groote Schuur Hospital
    S Afr Med J 102:532-6. 2012
  2. doi request reprint Polymyositis in African HIV-infected subjects
    J M Heckmann
    Division of Neurology, Department of Medicine, Groote Schuur Hospital and University of Cape Town, South Africa
    Neuromuscul Disord 20:735-9. 2010
  3. pmc A functional SNP in the regulatory region of the decay-accelerating factor gene associates with extraocular muscle pareses in myasthenia gravis
    J M Heckmann
    Neurology Research Group, Department of Medicine, University of Cape Town, Cape Town, South Africa
    Genes Immun 11:1-10. 2010
  4. ncbi request reprint Beware of 'normal' creatine kinase levels in HIV-associated polymyositis
    C Kenyon
    University of Cape Town
    S Afr Med J 100:156-7. 2010
  5. pmc A single-blinded trial of methotrexate versus azathioprine as steroid-sparing agents in generalized myasthenia gravis
    Jeannine M Heckmann
    Department of Medicine, Division of Neurology, University of Cape Town, Observatory, Cape Town, 7925, South Africa
    BMC Neurol 11:97. 2011
  6. ncbi request reprint Incidence of seropositive myasthenia gravis in Cape Town and South Africa
    K J Bateman
    Division of Neurology, Groote Schuur Hospital and University of Cape Town
    S Afr Med J 97:959-62. 2007
  7. ncbi request reprint Myasthenia gravis in South Africans: racial differences in clinical manifestations
    J M Heckmann
    Division of Neurology, E8 74, Groote Schuur Hospital and University of Cape Town Observatory, 7925, South Africa
    Neuromuscul Disord 17:929-34. 2007
  8. doi request reprint Sensory polyneuropathy in human immunodeficiency virus-infected patients receiving tuberculosis treatment
    C M Centner
    Neurology Research Group, Department of Medicine, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 18:27-33. 2014
  9. doi request reprint Association of transforming growth factor β-1 (TGFB1) regulatory region polymorphisms with myasthenia gravis-related ophthalmoparesis
    M V Akinyi
    Neurology Research Group, Department of Medicine, Groote Schuur Hospital and University of Cape Town, Cape Town 7925, South Africa
    J Neuroimmunol 246:96-9. 2012
  10. doi request reprint Predictive testing for Huntington disease in a developing country
    M J Futter
    Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa
    Clin Genet 75:92-7. 2009

Collaborators

Detail Information

Publications11

  1. ncbi request reprint The characteristics of juvenile myasthenia gravis among South Africans
    Jeannine M Heckmann
    Division of Neurology, Department of Medicine, Groote Schuur Hospital
    S Afr Med J 102:532-6. 2012
    ..To report the characteristics of juvenile-onset (<20 years) myasthenia gravis (MG) in Africa...
  2. doi request reprint Polymyositis in African HIV-infected subjects
    J M Heckmann
    Division of Neurology, Department of Medicine, Groote Schuur Hospital and University of Cape Town, South Africa
    Neuromuscul Disord 20:735-9. 2010
    ....
  3. pmc A functional SNP in the regulatory region of the decay-accelerating factor gene associates with extraocular muscle pareses in myasthenia gravis
    J M Heckmann
    Neurology Research Group, Department of Medicine, University of Cape Town, Cape Town, South Africa
    Genes Immun 11:1-10. 2010
    ..Susceptible individuals may benefit from anti-complement therapy in addition to immunosuppression...
  4. ncbi request reprint Beware of 'normal' creatine kinase levels in HIV-associated polymyositis
    C Kenyon
    University of Cape Town
    S Afr Med J 100:156-7. 2010
    ..However, muscle inflammation can be associated with normal or near-normal CK levels. We report 4 cases of HIV-associated polymyositis in which the diagnosis was almost missed owing to the absence of raised CK levels...
  5. pmc A single-blinded trial of methotrexate versus azathioprine as steroid-sparing agents in generalized myasthenia gravis
    Jeannine M Heckmann
    Department of Medicine, Division of Neurology, University of Cape Town, Observatory, Cape Town, 7925, South Africa
    BMC Neurol 11:97. 2011
    ..We evaluated the steroid-sparing efficacy of MTX (17.5 mg weekly) compared with AZA (2.5 mg/kg daily) in subjects recently diagnosed with generalized MG by assessing their average monthly prednisone requirements...
  6. ncbi request reprint Incidence of seropositive myasthenia gravis in Cape Town and South Africa
    K J Bateman
    Division of Neurology, Groote Schuur Hospital and University of Cape Town
    S Afr Med J 97:959-62. 2007
    ..In the developed world the incidence of MG has increased, particularly among older individuals, but no epidemiological studies have been done on SPMG in Africa...
  7. ncbi request reprint Myasthenia gravis in South Africans: racial differences in clinical manifestations
    J M Heckmann
    Division of Neurology, E8 74, Groote Schuur Hospital and University of Cape Town Observatory, 7925, South Africa
    Neuromuscul Disord 17:929-34. 2007
    ..The racial variation in some phenotypic features of myasthenia gravis and outcome to therapy, highlights the need to study biological factors in different subgroups to develop a more rational approach to immuno-suppressive therapy...
  8. doi request reprint Sensory polyneuropathy in human immunodeficiency virus-infected patients receiving tuberculosis treatment
    C M Centner
    Neurology Research Group, Department of Medicine, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 18:27-33. 2014
    ..Vitamin B6 and genetically determined slow isoniazid (INH) acetylation are believed to play key roles in the development of SPN in a TB treatment setting...
  9. doi request reprint Association of transforming growth factor β-1 (TGFB1) regulatory region polymorphisms with myasthenia gravis-related ophthalmoparesis
    M V Akinyi
    Neurology Research Group, Department of Medicine, Groote Schuur Hospital and University of Cape Town, Cape Town 7925, South Africa
    J Neuroimmunol 246:96-9. 2012
    ....
  10. doi request reprint Predictive testing for Huntington disease in a developing country
    M J Futter
    Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa
    Clin Genet 75:92-7. 2009
    ..Strategies to address these aspects have been incorporated into the program and will be reassessed after 1 year...
  11. doi request reprint Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review
    J J Van der Watt
    Division of Neurology, Department of Medicine, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 15:722-8. 2011
    ....