Glenda E Gray

Summary

Affiliation: University of the Witwatersrand
Country: South Africa

Publications

  1. ncbi request reprint Effect of HIV on women
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    AIDS Read 16:365-8, 373-7. 2006
  2. ncbi request reprint Pain in women with HIV/AIDS
    Glenda Gray
    Perinatal HIV Research Unit, University of Witwatersrand, Chris Hani Baragwanath Hosoital, Old Potch Road, Soweto, 1864 Johannesburg, Gauteng, South Africa
    Pain 132:S13-21. 2007
  3. pmc Development of a whole blood intracellular cytokine staining assay for mapping CD4(+) and CD8(+) T-cell responses across the HIV-1 genome
    Stephen Meddows-Taylor
    AIDS Virus Research Unit, National Institute for Communicable Diseases, and Department of Virology, University of the Witwatersrand, Johannesburg, South Africa
    J Virol Methods 144:115-21. 2007
  4. pmc Adolescent HIV-Cause for Concern in Southern Africa
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    PLoS Med 7:e1000227. 2010
  5. ncbi request reprint Recombinant adenovirus type 5 HIV gag/pol/nef vaccine in South Africa: unblinded, long-term follow-up of the phase 2b HVTN 503/Phambili study
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa South African Medical Research Council, Cape Town, South Africa Electronic address
    Lancet Infect Dis 14:388-96. 2014
  6. pmc Health diplomacy and the adaptation of global health interventions to local needs in sub-Saharan Africa and Thailand: evaluating findings from Project Accept (HPTN 043)
    Sebastian Kevany
    Institute for Health Policy Studies, University of California, San Francisco, 50 Beale Street, Suite 1300, San Francisco, CA 94105, USA
    BMC Public Health 12:459. 2012
  7. pmc Identification and characterisation of vaginal lactobacilli from South African women
    Sonal Pendharkar
    Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    BMC Infect Dis 13:43. 2013
  8. pmc HIV surveillance in a large, community-based study: results from the pilot study of Project Accept (HIV Prevention Trials Network 043)
    Estelle Piwowar-Manning
    Dept of Pathology, Johns Hopkins Univ, School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 11:251. 2011
  9. ncbi request reprint Immune-based prevention of mother-to-child HIV-1 transmission
    Glenda E Gray
    University of the Witwatersrand, Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, Soweto, Johannesburg, South Africa
    Curr Opin Mol Ther 9:168-75. 2007
  10. pmc HIV and pregnancy
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    BMJ 334:950-3. 2007

Detail Information

Publications61

  1. ncbi request reprint Effect of HIV on women
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    AIDS Read 16:365-8, 373-7. 2006
    ..In addition, women are more likely to have antiretroviral treatment side effects, and certain antiretroviral regimens may impair contraceptive efficacy. Prevention strategies are presently not female-controlled...
  2. ncbi request reprint Pain in women with HIV/AIDS
    Glenda Gray
    Perinatal HIV Research Unit, University of Witwatersrand, Chris Hani Baragwanath Hosoital, Old Potch Road, Soweto, 1864 Johannesburg, Gauteng, South Africa
    Pain 132:S13-21. 2007
    ..Unless the conditions under which women live are addressed, and attempts made to empower them in their daily lives, their limited ability to access treatment, care and pain relief will continue to be unacceptable...
  3. pmc Development of a whole blood intracellular cytokine staining assay for mapping CD4(+) and CD8(+) T-cell responses across the HIV-1 genome
    Stephen Meddows-Taylor
    AIDS Virus Research Unit, National Institute for Communicable Diseases, and Department of Virology, University of the Witwatersrand, Johannesburg, South Africa
    J Virol Methods 144:115-21. 2007
    ....
  4. pmc Adolescent HIV-Cause for Concern in Southern Africa
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    PLoS Med 7:e1000227. 2010
    ..Glenda Gray discusses the implications of a new study that found that almost half of all adolescents hospitalized in Zimbabwe were HIV-infected...
  5. ncbi request reprint Recombinant adenovirus type 5 HIV gag/pol/nef vaccine in South Africa: unblinded, long-term follow-up of the phase 2b HVTN 503/Phambili study
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa South African Medical Research Council, Cape Town, South Africa Electronic address
    Lancet Infect Dis 14:388-96. 2014
    ..Here we report long-term follow-up data...
  6. pmc Health diplomacy and the adaptation of global health interventions to local needs in sub-Saharan Africa and Thailand: evaluating findings from Project Accept (HPTN 043)
    Sebastian Kevany
    Institute for Health Policy Studies, University of California, San Francisco, 50 Beale Street, Suite 1300, San Francisco, CA 94105, USA
    BMC Public Health 12:459. 2012
    ..We report on the adaptations development, approval and implementation process from the Project Accept voluntary counseling and testing, community mobilization and post-test support services intervention...
  7. pmc Identification and characterisation of vaginal lactobacilli from South African women
    Sonal Pendharkar
    Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    BMC Infect Dis 13:43. 2013
    ..In this study, we have therefore identified the vaginal Lactobacillus species in a group of 40 African women from Soweto, a township on the outskirts of Johannesburg, South Africa...
  8. pmc HIV surveillance in a large, community-based study: results from the pilot study of Project Accept (HIV Prevention Trials Network 043)
    Estelle Piwowar-Manning
    Dept of Pathology, Johns Hopkins Univ, School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 11:251. 2011
    ..We evaluated the accuracy of in-country HIV rapid testing and determined HIV prevalence in the Project Accept pilot study...
  9. ncbi request reprint Immune-based prevention of mother-to-child HIV-1 transmission
    Glenda E Gray
    University of the Witwatersrand, Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, Soweto, Johannesburg, South Africa
    Curr Opin Mol Ther 9:168-75. 2007
    ....
  10. pmc HIV and pregnancy
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    BMJ 334:950-3. 2007
  11. ncbi request reprint Antiviral activity of nucleoside analogues during short-course monotherapy or dual therapy: its role in preventing HIV infection in infants
    Glenda Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, South Africa
    J Acquir Immune Defic Syndr 42:169-76. 2006
    ....
  12. ncbi request reprint A randomized trial of two postexposure prophylaxis regimens to reduce mother-to-child HIV-1 transmission in infants of untreated mothers
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg South Africa
    AIDS 19:1289-97. 2005
    ..Where women do not access antenatal care or HIV testing, postexposure prophylaxis to the infant may be an important preventative strategy...
  13. pmc Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study
    Glenda E Gray
    Perinatal HIV Research Unit, University of Witwatersrand, Johannesburg, South Africa
    Lancet Infect Dis 11:507-15. 2011
    ..We aim to assess the safety and efficacy of the vaccine in South Africa, where the major circulating clade is subtype C...
  14. pmc Overview of STEP and Phambili trial results: two phase IIb test-of-concept studies investigating the efficacy of MRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine
    Glenda Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    Curr Opin HIV AIDS 5:357-61. 2010
    ....
  15. pmc Natural killer cells that respond to human immunodeficiency virus type 1 (HIV‐1) peptides are associated with control of HIV‐1 infection
    Caroline T Tiemessen
    AIDS Virus Research Unit, National Institute for Communicable Diseases and Department of Virology, Coronation Women and Children Hospital, Enhancing Childhood HIV Outcomes, University of the Witwatersrand, Johannesburg, South Africa
    J Infect Dis 202:1444-53. 2010
    ..Peptide‐specific natural killer cells are associated with markers of less severe disease progression among HIV‐1-infected women (lower viral load and higher CD4 T cell count) and with stronger HIV‐specific T cell responses...
  16. pmc Host CCL3L1 gene copy number in relation to HIV-1-specific CD4+ and CD8+ T-cell responses and viral load in South African women
    Sharon Shalekoff
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 48:245-54. 2008
    ..017), and women who had CD4 and CD8 Gag-specific responses had significantly lower viral loads (P=0.004) and higher CCL3L1 copy number (P=0.015) than those women with only CD8 Gag-specific responses...
  17. pmc Efficacy of short-course AZT plus 3TC to reduce nevirapine resistance in the prevention of mother-to-child HIV transmission: a randomized clinical trial
    James A McIntyre
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    PLoS Med 6:e1000172. 2009
    ....
  18. pmc Natural killer cell responses to HIV-1 peptides are associated with more activating KIR genes and HLA-C genes of the C1 allotype
    Caroline T Tiemessen
    National Institute for Communicable Diseases, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 57:181-9. 2011
    ..What characterizes individuals whose natural killer (NK) cells are able to respond to HIV-1 peptides is not known...
  19. pmc In vivo effects of HIV-1 exposure in the presence and absence of single-dose nevirapine on cellular plasma activation markers of infants born to HIV-1-seropositive mothers
    Diana B Schramm
    AIDS Virus Research Unit, National Institute for Communicable Diseases and Department of Virology, University of the Witwatersrand, Gauteng, South Africa
    J Acquir Immune Defic Syndr 42:545-53. 2006
    ....
  20. pmc KIR-HLA and maternal-infant HIV-1 transmission in sub-Saharan Africa
    Maria Paximadis
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    PLoS ONE 6:e16541. 2011
    ..In conclusion this study has identified a number of significant associations that suggest an important role for NK cells in maternal-to-infant HIV-1 transmission...
  21. ncbi request reprint Combining PMTCT with active case finding for tuberculosis
    Paula B N Kali
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 42:379-81. 2006
    ..We conclude that rates of TB in HIV-infected pregnant women are high, and screening for TB during routine antenatal care should be implemented in high HIV-prevalence settings...
  22. pmc Pregnancy incidence and correlates during the HVTN 503 Phambili HIV vaccine trial conducted among South African women
    Mary H Latka
    The Aurum Institute, Johannesburg, South Africa
    PLoS ONE 7:e31387. 2012
    ..Using data from the HVTN 503/"Phambili" vaccine trial, we report pregnancy incidence during and after the vaccination period and identify factors, measured at screening, associated with incident pregnancy...
  23. doi request reprint KIR2DS4 allelic variants: Differential effects on in utero and intrapartum HIV-1 mother-to-child transmission
    Heather A Hong
    Centre for HIV and STIs, National Institute for Communicable Diseases, NHLS, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Clin Immunol 149:498-508. 2013
    ..005, OR=3.84); whilst in M-I+ discordance, infant possession of KIR2DS4-v was associated with increased risk of IU acquisition (P=0.002; OR=6.40). This study highlights the importance of KIR2DS4 in HIV-1 transmission/acquisition. ..
  24. pmc Progression and regression of premalignant cervical lesions in HIV-infected women from Soweto: a prospective cohort
    Tanvier Omar
    Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 25:87-94. 2011
    ..To ascertain progression and regression of cervical dysplasia in HIV-infected women in Soweto...
  25. pmc Low maternal viral loads and reduced granulocyte-macrophage colony-stimulating factor levels characterize exposed, uninfected infants who develop protective human immunodeficiency virus type 1-specific responses
    Diana B Schramm
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Department of Virology, University of the Witwatersrand, Gauteng, South Africa
    Clin Vaccine Immunol 14:348-54. 2007
    ....
  26. ncbi request reprint High rates of HIV in surgical patients in Soweto, South Africa: impact on resource utilisation and recommendations for HIV testing
    Neil A Martinson
    Perinatal HIV Research Unit, University of Witwatersrand, Johannesburg, South Africa
    Trans R Soc Trop Med Hyg 101:176-82. 2007
    ..WHO clinical staging of HIV should include anal sepsis as an indicator of advanced HIV disease...
  27. pmc Reduced ability of newborns to produce CCL3 is associated with increased susceptibility to perinatal human immunodeficiency virus 1 transmission
    Stephen Meddows-Taylor
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Department of Virology, University of the Witwatersrand, Sandringham, Johannesburg 2131, South Africa
    J Gen Virol 87:2055-65. 2006
    ..Our findings suggest that infants who display a deficient-production phenotype of CCL3 are at increased risk of acquiring HIV-1, indicating that this chemokine in particular plays an essential role in protective immunity...
  28. pmc Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers
    Sharon Shalekoff
    AIDS Virus Research Unit, National Institute for Communicable Diseases, and Department of Virology, Johannesburg, South Africa
    Clin Diagn Lab Immunol 11:229-34. 2004
    ..5 months and increased between 9 and 15 months to levels approaching those of uninfected adults. Proportions of CCR5-expressing cells, however, were very low in cord blood and subsequently increased with age...
  29. ncbi request reprint Comparative costs of inpatient care for HIV-infected and uninfected children and adults in Soweto, South Africa
    Leena S Thomas
    School of Public Health, University of the Witwatersrand, and Gauteng Department of Health, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 46:410-6. 2007
    ..HIV/AIDS creates a massive burden of care for health systems. A better understanding of the impact of HIV infection on health care utilization and costs may enable better use of limited resources...
  30. ncbi request reprint Characterisation of near-full length genome sequences of three South African human immunodeficiency virus type 1 subtype C isolates
    Gillian M Hunt
    AIDS Virus Research Unit, National Institute for Communicable Diseases and Department of Virology, University of the Witwatersrand, Johannesburg, South Africa
    Virus Genes 26:49-56. 2003
    ..This information contributes to our overall knowledge of circulating strains in South Africa and to the making of effective vaccines and chemotherapeutic agents...
  31. pmc What can we do to reduce mother to child transmission of HIV?
    James Mcintyre
    Perinatal HIV Research Unit, University of the Witwatersrand, Chris Hani Baragwanath Hospital, PO Bertsham, Johannesburg 2013, South Africa
    BMJ 324:218-21. 2002
  32. pmc Insensitivity of paediatric HIV-1 subtype C viruses to broadly neutralising monoclonal antibodies raised against subtype B
    Elin Solomonovna Gray
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    PLoS Med 3:e255. 2006
    ..To assess the suitability of such an approach, we determined the sensitivity of paediatric HIV-1 subtype C viruses to the broadly neutralising MAbs IgG1b12, 2G12, 2F5, and 4E10...
  33. ncbi request reprint Correlates of sexual risk among sexual minority and heterosexual South african youths
    Idia B Thurston
    Idia B Thurston is with the Department of Psychology, University of Memphis, Memphis, TN Janan Dietrich, Kennedy N Otwombe, Busiswe Nkala, and Glenda E Gray are with the Perinatal HIV Research Unit, University of the Witwatersrand, Chris Hani Baragwanath Hospital, Johannesburg, South Africa Laura M Bogart is with Boston Children s Hospital and the Harvard Medical School, Boston, MA Kathleen J Sikkema is with the Department of Psychology and Neuroscience, Duke University, Durham, NC
    Am J Public Health 104:1265-9. 2014
    ..90; SE = 0.95; P < .001) and were more likely to engage in sex trading (OR = 3.11; CI = 1.12-8.62; P < .05). South African SMYs are at increased risk relative to their heterosexual peers. ..
  34. ncbi request reprint Predictors of parent-adolescent communication in post-apartheid South Africa: a protective factor in adolescent sexual and reproductive health
    Jenny Coetzee
    Perinatal HIV Research Unit, University of the Witwatersrand, Chris Hani Baragwanath Hospital, Johannesburg 1864, South Africa Department of Human and Community Development, University of the Witwatersrand, Johannesburg 2000, South Africa Canadian African Prevention Trials Network, Ottawa Hospital General Campus, Ottawa, ON K1H 8L6, Canada Electronic address
    J Adolesc 37:313-24. 2014
    ..15-0.89). Overall levels of parent-adolescent communication in South Africa are low. HIV prevention programmes for South African adolescents should include information and skills regarding effective parent-adolescent communication...
  35. pmc Effect of Maternal HIV-1 Status and Antiretroviral Drugs on Haematological Profiles of South African Infants in Early Life
    Diana B Schramm
    AIDS Virus Research Unit, National Institute for Communicable Diseases and Department of Virology, University of the Witwatersrand, Gauteng, South Africa
    Open AIDS J 4:156-65. 2010
    ..These previously undescribed features may affect immune response capability in early life and clinical consequences of such changes need to be further investigated...
  36. pmc Willingness to participate in biomedical HIV prevention studies after the HVTN 503/Phambili trial: a survey conducted among adolescents in Soweto, South Africa
    Kennedy N Otwombe
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 58:211-8. 2011
    ..Adolescents' overall willingness to participate (WTP) in biomedical HIV prevention trials was examined, including after the prematurely discontinued phase IIb HVTN 503/Phambili HIV vaccine trial, in Soweto, South Africa...
  37. ncbi request reprint Tuberculosis active case-finding in a mother-to-child HIV transmission prevention programme in Soweto, South Africa
    Jean Nachega
    Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 17:1398-400. 2003
  38. doi request reprint Male circumcision for HIV prevention: developments from sub-Saharan Africa
    Guy de Bruyn
    Perinatal HIV Research Unit, New Nurses Home, Chris Hani Baragwanath Hospital, Chris Hani Road, Johannesburg, South Africa
    Expert Rev Anti Infect Ther 8:23-31. 2010
    ..This perspective reviews recent research findings and provides a summary of progress in various countries...
  39. ncbi request reprint Low frequency of the V106M mutation among HIV-1 subtype C-infected pregnant women exposed to nevirapine
    Lynn Morris
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Sandringham, Johannesburg, South Africa
    AIDS 17:1698-700. 2003
    ..V106M is a novel resistance mutation found in subtype C viruses exposed to efavirenz. This mutation is thus also induced at a low frequency in subtype C viruses exposed to single dose nevirapine...
  40. ncbi request reprint Viral dynamics and CD4+ T cell counts in subtype C human immunodeficiency virus type 1-infected individuals from southern Africa
    Clive M Gray
    National Institute for Communicable Diseases, Johannesburg, South Africa
    AIDS Res Hum Retroviruses 21:285-91. 2005
    ....
  41. pmc Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants
    Shabir A Madhi
    Department of Science National Research Foundation, Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South Africa
    J Infect Dis 202:355-61. 2010
    ..Nevertheless, M-/I- infants had superior OPA responses, compared with those in HIV+/ART+ infants, who in turn had better OPA responses, compared with those in HIV+/ART- infants...
  42. pmc Knowledge and attitudes towards HIV vaccines among Soweto adolescents
    Guy de Bruyn
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    BMC Res Notes 1:76. 2008
    ..All pupils within the selected schools from whom parental consent and child assent could be obtained were eligible for participation. A self-administered, facilitated questionnaire was completed by all participants...
  43. doi request reprint Development of phenotypic HIV-1 drug resistance after exposure to single-dose nevirapine
    Adriaan E Basson
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 49:538-43. 2008
    ..To assess the levels of phenotypic resistance conferred by these mutations, we examined the ability of sample-derived HIV-1 reverse transcriptase to function in the presence of nevirapine (NVP)...
  44. ncbi request reprint HIV-1 subtype C reverse transcriptase sequences from drug-naive pregnant women in South Africa
    Candice Pillay
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Sandringham 2131, Johannesburg, South Africa
    AIDS Res Hum Retroviruses 18:605-10. 2002
    ....
  45. doi request reprint A qualitative assessment of decisions affecting contraceptive utilization and fertility intentions among HIV-positive women in Soweto, South Africa
    Fatima Laher
    Perinatal HIV Research Unit, University of the Witwatersrand, Diepkloof, P O Box 114, Johannesburg, Soweto, 1864, South Africa
    AIDS Behav 13:47-54. 2009
    ..Routine counseling about pregnancy desires and contraception should be offered to HIV-positive women...
  46. pmc Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load
    Agatha Masemola
    National Institute for Communicable Diseases, Johannesburg, South Africa
    J Virol 78:3233-43. 2004
    ..These data have significance for the design of vaccines and for interpretation of vaccine-induced responses...
  47. ncbi request reprint Genotypic and phenotypic characterization of viral isolates from HIV-1 subtype C-infected children with slow and rapid disease progression
    Isaac Choge
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    AIDS Res Hum Retroviruses 22:458-65. 2006
    ..Similar to adults, CXCR4 usage was uncommon among HIV-1 subtype C isolates from pediatric infections...
  48. doi request reprint A steady state of CD4+ T cell memory maturation and activation is established during primary subtype C HIV-1 infection
    Pholo Maenetje
    AIDS Research Unit, National Institute for Communicable Diseases, Johannesburg, Gauteng, South Africa
    J Immunol 184:4926-35. 2010
    ....
  49. doi request reprint Role of menstruation in contraceptive choice among HIV-infected women in Soweto, South Africa
    Fatima Laher
    Perinatal HIV Research Unit, Soweto, Johannesburg, Gauteng Province, South Africa
    Contraception 81:547-51. 2010
    ..It is unknown whether HIV-infected women are more sensitive to menstrual changes and how this affects contraceptive choice. This study describes perceptions toward menses and contraceptive-induced amenorrhea among HIV-infected women...
  50. ncbi request reprint Novel and promiscuous CTL epitopes in conserved regions of Gag targeted by individuals with early subtype C HIV type 1 infection from southern Africa
    Agatha M Masemola
    National Institute for Communicable Diseases, University of Witwatersrand, Johannesburg, South Africa
    J Immunol 173:4607-17. 2004
    ....
  51. ncbi request reprint The NEAT study: a 48-week open-label study to compare the antiviral efficacy and safety of GW433908 versus nelfinavir in antiretroviral therapy-naive HIV-1-infected patients
    Amalia Rodriguez-French
    Centro de Vacunas y Tratamiento de Enfermedades Febriles, Centro Especializado y Hospital Pediátrico San Fernando, La Sabana, Panama
    J Acquir Immune Defic Syndr 35:22-32. 2004
    ..To compare the efficacy, durability, and tolerability of GW433908 (908), 1400 mg twice-daily (BID), with nelfinavir (NFV), 1250 mg BID...
  52. doi request reprint Breast-feeding, antiretroviral prophylaxis, and HIV
    Glenda E Gray
    N Engl J Med 359:189-91. 2008
  53. ncbi request reprint Transmission rates in consecutive pregnancies exposed to single-dose nevirapine in Soweto, South Africa and Abidjan, Côte d'Ivoire
    Neil A Martinson
    School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 45:206-9. 2007
    ..Because sdNVP selects resistance in a high percentage of women, we compared the effectiveness of sdNVP in preventing peripartum MTCT in successive pregnancies...
  54. pmc Predicting the impact of a partially effective HIV vaccine and subsequent risk behavior change on the heterosexual HIV epidemic in low- and middle-income countries: A South African example
    Kyeen M Andersson
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06510, USA
    J Acquir Immune Defic Syndr 46:78-90. 2007
    ..Even modestly effective HIV vaccines can confer enormous benefits in terms of HIV infections averted and decreased HIV prevalence. However, programs to reduce risk behavior may be important components of successful vaccination campaigns...
  55. ncbi request reprint Gender-based violence, relationship power, and risk of HIV infection in women attending antenatal clinics in South Africa
    Kristin L Dunkle
    Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA
    Lancet 363:1415-21. 2004
    ..No study on women has yet assessed gender-based violence as a risk factor for HIV after adjustment for women's own high-risk behaviours, although these are known to be associated with experience of violence...
  56. ncbi request reprint Prevalence and patterns of gender-based violence and revictimization among women attending antenatal clinics in Soweto, South Africa
    Kristin L Dunkle
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48104 3028, USA
    Am J Epidemiol 160:230-9. 2004
    ..92, 4.98). This study confirms the need for increased attention by the public health community to primary and secondary prevention of gender-based violence, with a specific need to reduce risk among South African adolescents...
  57. pmc African infants' CCL3 gene copies influence perinatal HIV transmission in the absence of maternal nevirapine
    Louise Kuhn
    Gertrude H Sergievsky Centre, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    AIDS 21:1753-61. 2007
    ..We investigated whether maternal or infant CCL3L1 gene copy numbers are associated with perinatal HIV transmission when single-dose nevirapine is given for prevention...
  58. ncbi request reprint Transactional sex among women in Soweto, South Africa: prevalence, risk factors and association with HIV infection
    Kristin L Dunkle
    Department of Epidemiology, University of Michigan, 611 Church Street, Ann Arbor, MI 48109 3028, USA
    Soc Sci Med 59:1581-92. 2004
    ..Research, policy and programmatic initiatives should consider the role of transactional sex in women's HIV risk, with attention to the intersecting roles of violence, poverty, and substance use in shaping women's sexual behaviour...
  59. doi request reprint Walking the tightrope in prevention of mother-to-child transmission of HIV infection
    Glenda E Gray
    Clin Infect Dis 46:622-4. 2008
  60. ncbi request reprint Co-trimoxazole prophylaxis in African children with HIV-1
    Shabir A Madhi
    Lancet 365:749-50; author reply 750-1. 2005
  61. ncbi request reprint Scientific justification for the participation of children and adolescents in HIV-1 vaccine trials in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, South Africa
    S Afr Med J 95:685-7. 2005