H Geldenhuys

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. pmc Lessons learnt from the first efficacy trial of a new infant tuberculosis vaccine since BCG
    Michele Tameris
    South African TB Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine IIDMM and School of Child and Adolescent Health, University of Cape Town, Brewelskloof Hospital, Haarlem Street, Worcester, Western Cape 6850, South Africa Electronic address
    Tuberculosis (Edinb) 93:143-9. 2013
  2. doi request reprint Analysis of time to regulatory and ethical approval of SATVI TB vaccine trials in South Africa
    H Geldenhuys
    South African Tuberculosis Vaccine Initiative SATVI, Institute of Infectious Disease and Molecular Medicine IIDMM, University of Cape Town, South Africa
    S Afr Med J 103:85-9. 2013
  3. doi request reprint Vaccine trials in the developing world: operational lessons learnt from a phase IV poliomyelitis vaccine trial in South Africa
    H Geldenhuys
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Diseases and Molecular Medicine IIDMM, University of Cape Town, South Africa
    Vaccine 30:5839-43. 2012
  4. doi request reprint Safety and tolerability of sputum induction in adolescents and adults with suspected pulmonary tuberculosis
    H D Geldenhuys
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Eur J Clin Microbiol Infect Dis 31:529-37. 2012
  5. ncbi request reprint The tuberculin skin test: a comparison of ruler and calliper readings
    H Geldenhuys
    South African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 14:1266-71. 2010
  6. doi request reprint Tuberculosis case finding for vaccine trials in young children in high-incidence settings: a randomised trial
    S Moyo
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 16:185-91. 2012
  7. doi request reprint Tuberculin skin test and QuantiFERON® assay in young children investigated for tuberculosis in South Africa
    S Moyo
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 15:1176-81, i. 2011
  8. ncbi request reprint Age-related tuberculosis incidence and severity in children under 5 years of age in Cape Town, South Africa
    S Moyo
    South African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 14:149-54. 2010
  9. doi request reprint Risky behaviour and psychosocial correlates in adolescents - is there a link with tuberculosis?
    H Geldenhuys
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Diseases and Molecular Medicine IIDMM, University of Cape Town, South Africa
    Afr J Psychiatry (Johannesbg) 14:383-7. 2011
  10. doi request reprint Sputum induction for the diagnosis of pulmonary tuberculosis: a systematic review and meta-analysis
    Y Gonzalez-Angulo
    South African Tuberculosis Vaccine Initiative SATVI, Wernher Beit Building N2 10, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa
    Eur J Clin Microbiol Infect Dis 31:1619-30. 2012

Collaborators

  • M Hatherill
  • H Mahomed
  • S Moyo
  • Suzanne Verver
  • D J Stein
  • M Pai
  • Michele Tameris
  • Y Gonzalez-Angulo
  • Angelique K K Luabeya
  • Jacqui Shea
  • Bernard Landry
  • Gregory Hussey
  • Willem Hanekom
  • Stephen Lockhart
  • Helen McShane
  • Thomas Scriba
  • J Bruce McClain
  • Marwou de Kock
  • Linda van der Merwe
  • Robert Walker
  • W Hanekom
  • G Hussey
  • C S Wiysonge

Detail Information

Publications10

  1. pmc Lessons learnt from the first efficacy trial of a new infant tuberculosis vaccine since BCG
    Michele Tameris
    South African TB Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine IIDMM and School of Child and Adolescent Health, University of Cape Town, Brewelskloof Hospital, Haarlem Street, Worcester, Western Cape 6850, South Africa Electronic address
    Tuberculosis (Edinb) 93:143-9. 2013
    ..A phase IIb trial of a candidate vaccine, MVA85A, was conducted in a high burden setting in South Africa to evaluate proof-of-concept efficacy for prevention of TB in infants...
  2. doi request reprint Analysis of time to regulatory and ethical approval of SATVI TB vaccine trials in South Africa
    H Geldenhuys
    South African Tuberculosis Vaccine Initiative SATVI, Institute of Infectious Disease and Molecular Medicine IIDMM, University of Cape Town, South Africa
    S Afr Med J 103:85-9. 2013
    ..Delays in regulatory and ethical approval may affect operational and budget planning and clinical development of the product...
  3. doi request reprint Vaccine trials in the developing world: operational lessons learnt from a phase IV poliomyelitis vaccine trial in South Africa
    H Geldenhuys
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Diseases and Molecular Medicine IIDMM, University of Cape Town, South Africa
    Vaccine 30:5839-43. 2012
    ..Conducting vaccine trials in developing nations is necessary but operationally complex. We describe operational lessons learnt from a phase IV poliomyelitis vaccine trial in a semi-rural region of South Africa...
  4. doi request reprint Safety and tolerability of sputum induction in adolescents and adults with suspected pulmonary tuberculosis
    H D Geldenhuys
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Eur J Clin Microbiol Infect Dis 31:529-37. 2012
    ..No serious adverse events occurred. Induced sputum is safe, tolerable, and feasible in adult and adolescent TB suspects in a community healthcare setting...
  5. ncbi request reprint The tuberculin skin test: a comparison of ruler and calliper readings
    H Geldenhuys
    South African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 14:1266-71. 2010
    ..TST skin induration may be measured either by a transparent ruler or by a pair of callipers. We hypothesised that the type of instrument used may affect the reading...
  6. doi request reprint Tuberculosis case finding for vaccine trials in young children in high-incidence settings: a randomised trial
    S Moyo
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 16:185-91. 2012
    ..A high tuberculosis (TB) burden rural area in South Africa...
  7. doi request reprint Tuberculin skin test and QuantiFERON® assay in young children investigated for tuberculosis in South Africa
    S Moyo
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 15:1176-81, i. 2011
    ..Although the literature on interferon-gamma release assays on tuberculosis (TB) in children has increased, data pertaining to young children remain relatively limited...
  8. ncbi request reprint Age-related tuberculosis incidence and severity in children under 5 years of age in Cape Town, South Africa
    S Moyo
    South African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town, South Africa
    Int J Tuberc Lung Dis 14:149-54. 2010
    ..Limited data are available on the characteristics of tuberculosis (TB) disease in young children, especially in high-burden countries...
  9. doi request reprint Risky behaviour and psychosocial correlates in adolescents - is there a link with tuberculosis?
    H Geldenhuys
    South African Tuberculosis Vaccine Initiative, Institute of Infectious Diseases and Molecular Medicine IIDMM, University of Cape Town, South Africa
    Afr J Psychiatry (Johannesbg) 14:383-7. 2011
    ..The study aimed to determine whether psychosocial and behavioural variables affect incidence of TB disease in adolescents...
  10. doi request reprint Sputum induction for the diagnosis of pulmonary tuberculosis: a systematic review and meta-analysis
    Y Gonzalez-Angulo
    South African Tuberculosis Vaccine Initiative SATVI, Wernher Beit Building N2 10, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa
    Eur J Clin Microbiol Infect Dis 31:1619-30. 2012
    ..The use of a particular nebulized saline concentration for SI cannot be recommended on the basis of this meta-regression analysis...