Collet Dandara

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. pmc Heterozygous p.Asp50Asn mutation in the GJB2 gene in two Cameroonian patients with keratitis-ichthyosis-deafness (KID) syndrome
    Ambroise Wonkam
    Division of Human Genetics, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Med Genet 14:81. 2013
  2. doi request reprint Direct-to-consumer genetic testing: To test or not to test, that is the question
    Collet Dandara
    Division of Human Genetics, University of Cape Town, South Africa
    S Afr Med J 103:510-2. 2013
  3. pmc PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients
    Marelize Swart
    Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa
    BMC Med Genet 13:112. 2012
  4. ncbi request reprint Confirmation of the recurrent ACVR1 617G>A mutation in South Africans with fibrodysplasia ossificans progressiva
    Collet Dandara
    Faculty of Health Sciences, University of Cape Town Medical School, South Africa
    S Afr Med J 102:631-3. 2012
  5. pmc The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer
    Dongping Li
    International Centre for Genetic Engineering and Biotechnology ICGEB, UCT Campus, Anzio Road Observatory 7925, Cape Town, South Africa
    BMC Genet 11:47. 2010
  6. pmc CCR2-V64I polymorphism is associated with increased risk of cervical cancer but not with HPV infection or pre-cancerous lesions in African women
    Koushik Chatterjee
    Division of Medical Virology and Institute of Infectious Disease and Molecular Medicine IIDMM, University of Cape Town, Cape Town, Republic of South Africa
    BMC Cancer 10:278. 2010
  7. ncbi request reprint Gene-environment interaction: the role of SULT1A1 and CYP3A5 polymorphisms as risk modifiers for squamous cell carcinoma of the oesophagus
    Collet Dandara
    UCT MRC Oesophageal Cancer Research Group, Division of Medical Biochemistry, Institute of Infectious Disease and Molecular Medicine IIDMM, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, South Africa
    Carcinogenesis 27:791-7. 2006
  8. ncbi request reprint Effect of rifampicin-based antitubercular therapy and the cytochrome P450 2B6 516G>T polymorphism on efavirenz concentrations in adults in South Africa
    Karen Cohen
    Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa
    Antivir Ther 14:687-95. 2009
  9. doi request reprint A Fas gene polymorphism influences herpes simplex virus type 2 infection in South African women
    Koushik Chatterjee
    Division of Medical Virology, Department of Clinical Laboratory Sciences and Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    J Med Virol 82:2082-6. 2010
  10. pmc ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients
    Marelize Swart
    Division of Human Genetics, Faculty of Health Sciences, University of Cape Town Observatory, Cape Town, South Africa
    Front Genet 3:236. 2012

Collaborators

Detail Information

Publications12

  1. pmc Heterozygous p.Asp50Asn mutation in the GJB2 gene in two Cameroonian patients with keratitis-ichthyosis-deafness (KID) syndrome
    Ambroise Wonkam
    Division of Human Genetics, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Med Genet 14:81. 2013
    ..KID appears to be genetically heterogeneous and most cases are caused by GJB2 mutations. Mutations in African patients have been rarely described...
  2. doi request reprint Direct-to-consumer genetic testing: To test or not to test, that is the question
    Collet Dandara
    Division of Human Genetics, University of Cape Town, South Africa
    S Afr Med J 103:510-2. 2013
    ..Guidelines and recommendations for DTC genetic testing in South Africa (SA) are currently lacking. We provide recommendations that seek to protect consumers and healthcare providers in SA from possible exploitation. ..
  3. pmc PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients
    Marelize Swart
    Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa
    BMC Med Genet 13:112. 2012
    ....
  4. ncbi request reprint Confirmation of the recurrent ACVR1 617G>A mutation in South Africans with fibrodysplasia ossificans progressiva
    Collet Dandara
    Faculty of Health Sciences, University of Cape Town Medical School, South Africa
    S Afr Med J 102:631-3. 2012
    ..The aim of the project was to determine whether or not this mutation is present in affected persons in South Africa...
  5. pmc The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer
    Dongping Li
    International Centre for Genetic Engineering and Biotechnology ICGEB, UCT Campus, Anzio Road Observatory 7925, Cape Town, South Africa
    BMC Genet 11:47. 2010
    ..Genetic polymorphisms in GSTs were investigated in 245 patients and 288 controls samples by PCR-RFLP analysis...
  6. pmc CCR2-V64I polymorphism is associated with increased risk of cervical cancer but not with HPV infection or pre-cancerous lesions in African women
    Koushik Chatterjee
    Division of Medical Virology and Institute of Infectious Disease and Molecular Medicine IIDMM, University of Cape Town, Cape Town, Republic of South Africa
    BMC Cancer 10:278. 2010
    ..CCR2-V64I polymorphism has been previously reported to influence the progression to cervical cancer in some populations and has also been associated with decreased progression from HIV infection to AIDS...
  7. ncbi request reprint Gene-environment interaction: the role of SULT1A1 and CYP3A5 polymorphisms as risk modifiers for squamous cell carcinoma of the oesophagus
    Collet Dandara
    UCT MRC Oesophageal Cancer Research Group, Division of Medical Biochemistry, Institute of Infectious Disease and Molecular Medicine IIDMM, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, South Africa
    Carcinogenesis 27:791-7. 2006
    ..The genotype results show that SULT1A1*2/*2 genotype is associated with increased risk for OC among subjects exposed to tobacco-smoke-related carcinogens...
  8. ncbi request reprint Effect of rifampicin-based antitubercular therapy and the cytochrome P450 2B6 516G>T polymorphism on efavirenz concentrations in adults in South Africa
    Karen Cohen
    Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa
    Antivir Ther 14:687-95. 2009
    ..We explored the effect of rifampicin-based antitubercular therapy and the 516G>T polymorphism on efavirenz concentrations in HIV-infected patients in South Africa...
  9. doi request reprint A Fas gene polymorphism influences herpes simplex virus type 2 infection in South African women
    Koushik Chatterjee
    Division of Medical Virology, Department of Clinical Laboratory Sciences and Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    J Med Virol 82:2082-6. 2010
    ..There was no significant association found with FasR-670A > G and FasL-844T > C polymorphisms and risk of HSV-2 infection. This is, to our knowledge, the first time a non-HLA genetic link with HSV-2 infection has been reported...
  10. pmc ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients
    Marelize Swart
    Division of Human Genetics, Faculty of Health Sciences, University of Cape Town Observatory, Cape Town, South Africa
    Front Genet 3:236. 2012
    ..ABCB1 plays a role in determining the plasma concentrations of efavirenz and should be taken into account in future design of assays for genotype-based dosing of efavirenz-containing regimens...
  11. doi request reprint High predictive value of CYP2B6 SNPs for steady-state plasma efavirenz levels in South African HIV/AIDS patients
    Marelize Swart
    Department of Clinical Laboratory Science, Division of Human Genetics, University of Cape Town, Cape Town, South Africa
    Pharmacogenet Genomics 23:415-27. 2013
    ....
  12. ncbi request reprint CYP3A5 genotypes and risk of oesophageal cancer in two South African populations
    Collet Dandara
    MRC UCT Oesophageal Cancer Research Group, Division of Medical Biochemistry, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town 7925, South Africa
    Cancer Lett 225:275-82. 2005
    ..025). Individuals homozygous for defective CYP3A5 had reduced risk of developing oesophageal cancer (P=0.032)...