A Coutsoudis

Summary

Affiliation: University of Natal
Country: South Africa

Publications

  1. ncbi Mother-to-child transmission of HIV-1 infection during exclusive breastfeeding in the first 6 months of life: an intervention cohort study
    Hoosen M Coovadia
    Centre for HIV AIDS Networking, University of KwaZulu Natal, South Africa
    Lancet 369:1107-16. 2007
  2. ncbi Flash-heat inactivation of HIV-1 in human milk: a potential method to reduce postnatal transmission in developing countries
    Kiersten Israel-Ballard
    Division of Epidemiology, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
    J Acquir Immune Defic Syndr 45:318-23. 2007
  3. ncbi Short communication: CD4 counts of HIV-infected pregnant women and their infected children--implications for PMTCT and treatment programmes
    Ankie Lebon
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
    Trop Med Int Health 12:1472-4. 2007
  4. ncbi Morbidity in children born to women infected with human immunodeficiency virus in South Africa: does mode of feeding matter?
    A Coutsoudis
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of Natal, Congella, South Africa
    Acta Paediatr 92:890-5. 2003
  5. ncbi Breast-feeding and HIV transmission: the jury is still out
    Anna Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, Private Bag 7, Congella 4013, South Africa
    J Pediatr Gastroenterol Nutr 36:434-42. 2003
  6. ncbi Infant feeding dilemmas created by HIV: South African experiences
    Anna Coutsoudis
    Department of Paediatrics and Child Health, University of KwaZulu Natal, South Africa
    J Nutr 135:956-9. 2005
  7. ncbi Free formula milk for infants of HIV-infected women: blessing or curse?
    A Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, Congella, South Africa
    Health Policy Plan 17:154-60. 2002
  8. ncbi Breastfeeding and risk of HIV transmission: an update
    Anna Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, South Africa
    Forum Nutr 56:162-4. 2003
  9. ncbi Routinely available cotrimoxazole prophylaxis and occurrence of respiratory and diarrhoeal morbidity in infants born to HIV-infected mothers in South Africa
    A Coutsoudis
    Department of Paediatrics and Child Health, University of KwaZulu Natal, Durban, South Africa
    S Afr Med J 95:339-45. 2005
  10. ncbi Method of feeding and transmission of HIV-1 from mothers to children by 15 months of age: prospective cohort study from Durban, South Africa
    A Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, Congella, South Africa
    AIDS 15:379-87. 2001

Collaborators

Detail Information

Publications45

  1. ncbi Mother-to-child transmission of HIV-1 infection during exclusive breastfeeding in the first 6 months of life: an intervention cohort study
    Hoosen M Coovadia
    Centre for HIV AIDS Networking, University of KwaZulu Natal, South Africa
    Lancet 369:1107-16. 2007
    ..We assessed the HIV-1 transmission risks and survival associated with exclusive breastfeeding and other types of infant feeding...
  2. ncbi Flash-heat inactivation of HIV-1 in human milk: a potential method to reduce postnatal transmission in developing countries
    Kiersten Israel-Ballard
    Division of Epidemiology, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
    J Acquir Immune Defic Syndr 45:318-23. 2007
    ..The World Health Organization recommends heat-treated breast milk as an infant-feeding alternative. We investigated the ability of a simple method, flash-heat, to inactivate HIV in breast milk from HIV-positive mothers...
  3. ncbi Short communication: CD4 counts of HIV-infected pregnant women and their infected children--implications for PMTCT and treatment programmes
    Ankie Lebon
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
    Trop Med Int Health 12:1472-4. 2007
    ..The antenatal-postnatal divide needs to be bridged with respect to the follow-up of both HIV-infected women and their exposed infants...
  4. ncbi Morbidity in children born to women infected with human immunodeficiency virus in South Africa: does mode of feeding matter?
    A Coutsoudis
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of Natal, Congella, South Africa
    Acta Paediatr 92:890-5. 2003
    ..To examine infant morbidity risks associated with refraining from breastfeeding where it is used in an attempt to prevent mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV)...
  5. ncbi Breast-feeding and HIV transmission: the jury is still out
    Anna Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, Private Bag 7, Congella 4013, South Africa
    J Pediatr Gastroenterol Nutr 36:434-42. 2003
  6. ncbi Infant feeding dilemmas created by HIV: South African experiences
    Anna Coutsoudis
    Department of Paediatrics and Child Health, University of KwaZulu Natal, South Africa
    J Nutr 135:956-9. 2005
    ..Mothers found it difficult to stop breast-feeding earlier than the norm, and it therefore is important that mothers considering early cessation of breast-feeding be given sufficient preparation and support...
  7. ncbi Free formula milk for infants of HIV-infected women: blessing or curse?
    A Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, Congella, South Africa
    Health Policy Plan 17:154-60. 2002
    ....
  8. ncbi Breastfeeding and risk of HIV transmission: an update
    Anna Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, South Africa
    Forum Nutr 56:162-4. 2003
  9. ncbi Routinely available cotrimoxazole prophylaxis and occurrence of respiratory and diarrhoeal morbidity in infants born to HIV-infected mothers in South Africa
    A Coutsoudis
    Department of Paediatrics and Child Health, University of KwaZulu Natal, Durban, South Africa
    S Afr Med J 95:339-45. 2005
    ..To examine the influence of cotrimoxazole (CTM) prophylaxis on incidence of lower respiratory tract infections (LRTIs) and diarrhoea...
  10. ncbi Method of feeding and transmission of HIV-1 from mothers to children by 15 months of age: prospective cohort study from Durban, South Africa
    A Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, Congella, South Africa
    AIDS 15:379-87. 2001
    ..To determine the risk of HIV transmission by infant feeding modality...
  11. ncbi Influence of infant-feeding patterns on early mother-to-child transmission of HIV-1 in Durban, South Africa: a prospective cohort study. South African Vitamin A Study Group
    A Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, South Africa
    Lancet 354:471-6. 1999
    ..We compared transmission rates in exclusively breastfed, mixed-fed, and formula-fed (never breastfed) infants to assess whether the pattern of breastfeeding is a critical determinant of early mother-to-child transmission of HIV-1...
  12. ncbi A health and nutritional profile of rural school children in KwaZulu-Natal, South Africa
    C C Jinabhai
    Department of Community Health, School of Family and Public Health Medicine, University of Natal, Private Bag 7, Congella 4013, Durban, South Africa
    Ann Trop Paediatr 21:50-8. 2001
    ..Micronutrient supplementation and de-worming provide opportunities for school-based health promotion and primary health care interventions, and might produce significant health and educational benefits...
  13. ncbi A randomized controlled trial of the effect of antihelminthic treatment and micronutrient fortification on health status and school performance of rural primary school children
    C C Jinabhai
    Department of Community Health, Nelson R Mandela School of Medicine, University of Natal, Durban, South Africa
    Ann Trop Paediatr 21:319-33. 2001
    ....
  14. ncbi Influence of infant feeding patterns on early mother-to-child transmission of HIV-1 in Durban, South Africa
    A Coutsoudis
    Department of Paediatrics and Child Health, University of Natal, Congella, South Africa
    Ann N Y Acad Sci 918:136-44. 2000
    ..If confirmed, exclusive breastfeeding may offer HIV-infected women in developing countries an affordable, culturally acceptable, and effective means of reducing MTCT of HIV-1 while maintaining the overwhelming benefits of breastfeeding...
  15. ncbi Secretory leukocyte protease inhibitor in vaginal fluids and perinatal human immunodeficiency virus type 1 transmission
    K Pillay
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of Natal, Private Bag 7, Congella, 4013, Republic of South Africa
    J Infect Dis 183:653-6. 2001
    ..174 virions/mL; P=.09). Increased concentrations of selected innate mucosal immune factors, such as SLPI, seem to be associated with reduced rates of perinatal HIV-1 transmission and may contribute to natural antiretroviral defense...
  16. ncbi Infant feeding counselling for HIV-infected and uninfected women: appropriateness of choice and practice
    R M Bland
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
    Bull World Health Organ 85:289-96. 2007
    ..To examine infant feeding intentions of HIV-infected and uninfected women and the appropriateness of their choices according to their home resources; and to determine their adherence to their intentions in the first postnatal week...
  17. ncbi Messages about dual contraception in areas of high HIV prevalence are not heeded
    N Ngubane
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, Durban
    S Afr Med J 98:209-12. 2008
    ..It is critical for HIV-negative women to prevent seroconversion and HIV transmission to their infants during pregnancy and breastfeeding...
  18. ncbi HIV in pregnancy: strategies for management
    H M Coovadia
    Department of Paediatrics and Child Health, University of Natal, Congella, 4013, South Africa
    Semin Neonatol 5:181-8. 2000
    ..Strategies suitable and inappropriate for developing countries, and operational difficulties, are discussed...
  19. ncbi Feeding mode, intestinal permeability, and neopterin excretion: a longitudinal study in infants of HIV-infected South African women
    N C Rollins
    Department of Pediatrics, University of Natal, Durban, South Africa
    J Acquir Immune Defic Syndr 28:132-9. 2001
    ..The effects of feeding mode on infant intestinal permeability or urinary neopterin excretion do not explain a possible protective effect of exclusive breast feeding on mother-to-child transmission of HIV...
  20. ncbi Rapid testing may not improve uptake of HIV testing and same day results in a rural South African community: a cohort study of 12,000 women
    Ntombizodumo B Mkwanazi
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, Durban, South Africa
    PLoS ONE 3:e3501. 2008
    ..We report on the acceptability of HIV counselling and testing, and uptake of results, before and after the introduction of rapid testing in this area...
  21. ncbi Growth in early childhood in a cohort of children born to HIV-1-infected women from Durban, South Africa
    R Bobat
    Department of Paediatrics, Nelson R Mandela School of Medicine, University of Natal, Private Bag 7, Congella 4013, South Africa
    Ann Trop Paediatr 21:203-10. 2001
    ..Early nutritional intervention might help prevent early progression or death in HIV-infected children, particularly in developing countries without access to anti-retroviral therapy in state hospitals...
  22. ncbi Epidemiology of helminth infections: implications for parasite control programmes, a South African perspective
    C C Jinabhai
    Department of Community Health, Nelson R Mandela School of Medicine, University of Natal, Congella, South Africa
    Public Health Nutr 4:1211-9. 2001
    ..To assess the South African government's parasite control policy...
  23. ncbi Duration, pattern of breastfeeding and postnatal transmission of HIV: pooled analysis of individual data from West and South African cohorts
    Renaud Becquet
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, Somkhele, South Africa
    PLoS ONE 4:e7397. 2009
    ..Both breastfeeding pattern and duration are associated with postnatal HIV acquisition; their relative contribution has not been reliably quantified...
  24. ncbi HIV, infant feeding and more perils for poor people: new WHO guidelines encourage review of formula milk policies
    Anna Coutsoudis
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu Natal, South Africa
    Bull World Health Organ 86:210-4. 2008
    ..Exclusive breastfeeding, which is threatened by the HIV epidemic, remains an unfailing anchor of child survival...
  25. ncbi GB virus type C coinfection in HIV-infected African mothers and their infants, KwaZulu Natal, South Africa
    Mahomed A Sathar
    Department of Medicine, Nelson R Mandela School of Medicine, Faculty of Health Sciences, University of Natal, Congella, Durban, South Africa
    Clin Infect Dis 38:405-9. 2004
    ..The immunological indices measured tend to suggest an association with protection and or delayed progression of HIV disease in GBV-C-infected mothers...
  26. ncbi Weight evolution and perceptions of adults living with HIV following initiation of antiretroviral therapy in a South African urban setting
    E Hurley
    Department of Family Medicine, University of KwaZulu Natal, Durban
    S Afr Med J 101:645-50. 2011
    ..Obesity and undernutrition are common in South Africa and influence the health outcomes of people living with the human immunodeficiency virus (PLHIV)...
  27. ncbi Vertical HIV transmission in South Africa: translating research into policy and practice
    Salim Abdool Karim
    University of Natal, 4041, South Africa
    Lancet 359:992-3. 2002
  28. ncbi Intervention to promote exclusive breast-feeding for the first 6 months of life in a high HIV prevalence area
    Ruth M Bland
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, KwaZulu Natal, South Africa
    AIDS 22:883-91. 2008
    ..We report on a nonrandomized intervention cohort study to increase exclusive breast-feeding rates for 6 months after delivery in HIV-positive and HIV-negative women in KwaZulu-Natal, South Africa...
  29. ncbi HIV, infant feeding, and survival: old wine in new bottles, but brimming with promise
    Hoosen M Coovadia
    Nelson Mandela School of Medicine, University of Kwazulu/Natal, 719 Umbilo Road, Congella 4013, South Africa
    AIDS 21:1837-40. 2007
  30. ncbi Breastfeeding and HIV
    Anna Coutsoudis
    Department of Paediatrics and Child Health, Room 261, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Private Bag 7, Congella 4013, South Africa
    Best Pract Res Clin Obstet Gynaecol 19:185-96. 2005
    ..The research agenda is very full as many questions still remain unanswered...
  31. ncbi Effects of the human immunodeficiency virus on tuberculosis in children
    P M Jeena
    Department of Paediatrics and Child Health, Faculty of Medicine, University of Natal, Congella, South Africa
    Tuber Lung Dis 77:437-43. 1996
    ..In children however, unlike in adults, very little has been documented about the interaction between the two diseases...
  32. ncbi Infant feeding, HIV transmission and mortality at 18 months: the need for appropriate choices by mothers and prioritization within programmes
    Nigel C Rollins
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Congella, South Africa
    AIDS 22:2349-57. 2008
    ..To determine the late HIV transmission and survival risks associated with early infant feeding practices...
  33. ncbi Breastfeeding and the HIV positive mother: the debate continues
    Anna Coutsoudis
    Department of Paediatrics and Child Health, Room 261, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Private Bag 7, Congella 4013, South Africa
    Early Hum Dev 81:87-93. 2005
    ..Anti-retroviral therapy to the mother and/or infant is likely to offer the possibility of maintaining breastfeeding as a safe option for HIV-infected women...
  34. ncbi HIV-Associated Tuberculosis in the Newborn and Young Infant
    M Adhikari
    Neonatal Team, Nelson R Mandela School of Medicine, University of KwaZulu Natal, P O Box 17049, Congella, Durban 4013, South Africa
    Int J Pediatr 2011:354208. 2011
    ..Perinatal outcomes are guarded even with treatment of both diseases. Exclusive breast feeding is recommended. The community and social impact are crippling. The social issues aggravate the prognosis of these two diseases...
  35. ncbi Pregnancy outcomes in HIV-infected and uninfected women in rural and urban South Africa
    Nigel C Rollins
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Congella 4013, South Africa
    J Acquir Immune Defic Syndr 44:321-8. 2007
    ..To describe pregnancy outcomes among clade C HIV-infected and uninfected women in South Africa...
  36. ncbi Scaling-up exclusive breastfeeding support programmes: the example of KwaZulu-Natal
    Chris Desmond
    Human Sciences Research Council, Durban, South Africa
    PLoS ONE 3:e2454. 2008
    ..We present a costing and cost effectiveness analysis of a successful intervention to promote EBF in high HIV prevalence area in South Africa, and implications for scale-up in the province of KwaZulu-Natal...
  37. ncbi The prevention of mother-to-child HIV transmission programme and infant feeding practices
    Anna Coutsoudis
    S Afr Med J 94:70. 2004
  38. ncbi Antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission
    Hoosen M Coovadia
    N Engl J Med 359:1846; author reply 1848. 2008
  39. ncbi Preventing postnatal transmission of HIV-1 through breast-feeding: modifying infant feeding practices
    Nigel Rollins
    Africa Centre for Health and Population Studies, Mtubatuba, South Africa
    J Acquir Immune Defic Syndr 35:188-95. 2004
    ..This may inform policy, programming, and training options and may be especially valuable in the absence of conclusive data on the efficacy of the interventions to be applied during the breast-feeding period...
  40. ncbi Breastmilk RNA viral load in HIV-infected South African women: effects of subclinical mastitis and infant feeding
    Juana F Willumsen
    Centre for International Child Health, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    AIDS 17:407-14. 2003
    ..Multivariate models had limited predictive value for milk RNA viral load, illustrating the multiple contributors to viral load...
  41. ncbi Reply to 'Mode of infant feeding and HIV infection in children in a program for prevention of mother-to-child transmission in Uganda' by Magoni et al
    Anna Coutsoudis
    AIDS 19:1718-9; author reply 1720-1. 2005
  42. ncbi Late postnatal transmission of HIV-1 in breast-fed children: an individual patient data meta-analysis
    Anna Coutsoudis
    J Infect Dis 189:2154-66. 2004
    ..Biological and cultural mechanisms underlying the association between sex and late postnatal transmission should be further investigated. Interventions to decrease transmission of HIV-1 through breast-feeding are urgently needed...
  43. ncbi Synergy between mannose-binding lectin gene polymorphisms and supplementation with vitamin A influences susceptibility to HIV infection in infants born to HIV-positive mothers
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and the Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Clin Nutr 84:610-5. 2006
    ..Mannose-binding lectin (MBL-2) allele variants are associated with deficiencies in innate immunity and have been found to be correlated with HIV infection in adults and children...
  44. ncbi Exclusive breast-feeding and HIV transmission
    Anna Coutsoudis
    AIDS 16:498-9. 2002
  45. ncbi Vitamin content of breast milk from HIV-1-infected mothers before and after flash-heat treatment
    Kiersten A Israel-Ballard
    Department of Pediatrics, University of California, Davis Medical Center, 2516 Stockton Boulevard, Room 334, Sacramento, CA 95817, USA
    J Acquir Immune Defic Syndr 48:444-9. 2008
    ..Flash-heat is a simple heat treatment method shown to inactivate cell-free HIV...