A Cornish-Bowden

Summary

Affiliation: University of Stellenbosch
Country: South Africa

Publications

  1. ncbi request reprint Co-response analysis: a new experimental strategy for metabolic control analysis
    J H Hofmeyr
    Dept of Biochemistry, University of Stellenbosch, South Africa
    J Theor Biol 182:371-80. 1996
  2. ncbi request reprint The reversible Hill equation: how to incorporate cooperative enzymes into metabolic models
    J H Hofmeyr
    Department of Biochemistry, University of Stellenbosch, South Africa
    Comput Appl Biosci 13:377-85. 1997
  3. ncbi request reprint Regulating the cellular economy of supply and demand
    J S Hofmeyr
    Department of Biochemistry, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa
    FEBS Lett 476:47-51. 2000
  4. ncbi request reprint Building the cellular puzzle: control in multi-level reaction networks
    J H Hofmeyr
    Department of Biochemistry, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa
    J Theor Biol 208:261-85. 2001
  5. ncbi request reprint The regulatory design of an allosteric feedback loop: the effect of saturation by pathway substrate
    Jan Hendrik Hofmeyr
    Department of Biochemistry, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa
    Biochem Soc Trans 30:19-25. 2002

Collaborators

  • J H Hofmeyr
  • Jan Hendrik Hofmeyr
  • J S Hofmeyr
  • Brett G Olivier
  • H V Westerhoff

Detail Information

Publications5

  1. ncbi request reprint Co-response analysis: a new experimental strategy for metabolic control analysis
    J H Hofmeyr
    Dept of Biochemistry, University of Stellenbosch, South Africa
    J Theor Biol 182:371-80. 1996
    ..The approach requires no quantitative information about the magnitudes of the effects on the individual enzyme activities, and consequently no enzymes need to be studied in isolation from the pathway...
  2. ncbi request reprint The reversible Hill equation: how to incorporate cooperative enzymes into metabolic models
    J H Hofmeyr
    Department of Biochemistry, University of Stellenbosch, South Africa
    Comput Appl Biosci 13:377-85. 1997
    ..There is a need, therefore, for approximate reversible equations that allow convenient simulation without violating thermodynamic constraints...
  3. ncbi request reprint Regulating the cellular economy of supply and demand
    J S Hofmeyr
    Department of Biochemistry, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa
    FEBS Lett 476:47-51. 2000
    ..One important result is the demonstration that when flux is controlled by one block, the other block determines to which degree the concentration of the linking metabolite is homeostatically maintained...
  4. ncbi request reprint Building the cellular puzzle: control in multi-level reaction networks
    J H Hofmeyr
    Department of Biochemistry, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa
    J Theor Biol 208:261-85. 2001
    ..This newly developed theory therefore makes it possible to quantitatively dissect intermodular, internal and external regulation in multi-level systems...
  5. ncbi request reprint The regulatory design of an allosteric feedback loop: the effect of saturation by pathway substrate
    Jan Hendrik Hofmeyr
    Department of Biochemistry, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa
    Biochem Soc Trans 30:19-25. 2002
    ..Combining the supply and demand rate characteristics allows us to explore both the control distribution at steady state and the regulatory performance of the system over a wide range of demand activities...