Research Topics
| David CoetzeeSummaryAffiliation: University of Cape Town Country: South Africa Publications
| Collaborators
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Detail Information
Publications
Promoting adherence to antiretroviral therapy: the experience from a primary care setting in Khayelitsha, South AfricaDavid Coetzee
Infectious Disease Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
AIDS 18:S27-31. 2004..To describe the approach used to promote adherence to antiretroviral therapy (ART) and to present the outcomes in the first primary care public sector ART project in South Africa...
Effectiveness of the first district-wide programme for the prevention of mother-to-child transmission of HIV in South AfricaDavid Coetzee
Infectious Disease Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
Bull World Health Organ 83:489-94. 2005....- Impact of human immunodeficiency virus 1 infection and inflammation on the composition and yield of cervical mononuclear cells in the female genital tractNonhlanhla N Nkwanyana
Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
Immunology 128:e746-57. 2009..In conclusion, we suggest that inflammation at the cervix and HIV infection are likely to be key determinants in the absolute number of mucosal immune cells recovered by cervical cytobrushing... 
Outcomes of nevirapine- and efavirenz-based antiretroviral therapy when coadministered with rifampicin-based antitubercular therapyAndrew Boulle
School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
JAMA 300:530-9. 2008..Rifampicin-based antitubercular therapy reduces the plasma concentrations of nevirapine and efavirenz. The virological consequences of these interactions are not well described...- Influence of human immunodeficiency virus and CD4 count on the prevalence of human papillomavirus in heterosexual couplesZizipho Z A Mbulawa
Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
J Gen Virol 91:3023-31. 2010..In contrast, female genital HPV prevalence and HPV type-specific sharing were determined by their own HIV-positive status and not by that of their male partner... - Correcting for mortality among patients lost to follow up on antiretroviral therapy in South Africa: a cohort analysisGilles Van Cutsem
Medecins Sans Frontieres, Cape Town, South Africa
PLoS ONE 6:e14684. 2011..We describe LTF before and after correction for mortality in a primary care ART programme with linkages to the national vital registration system... - Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha, South AfricaAndrew Boulle
School of Public Health and Family Medicine, University of Cape Town, Anzio Road, Cape Town, South Africa
AIDS 24:563-72. 2010..We report on outcomes after 7 years of a community-based antiretroviral therapy (ART) programme in Khayelitsha, South Africa, with death registry linkages to correct for mortality under-ascertainment... - The effect of complete integration of HIV and TB services on time to initiation of antiretroviral therapy: a before-after studyBernhard Kerschberger
Medecins Sans Frontieres, Khayelitsha, Cape Town, South Africa
PLoS ONE 7:e46988. 2012..We present a model of full TB/HIV integration and estimate its effect on time to initiation of ART... - Substitutions due to antiretroviral toxicity or contraindication in the first 3 years of antiretroviral therapy in a large South African cohortAndrew Boulle
Infectious Disease Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
Antivir Ther 12:753-60. 2007..The patterns and reasons for antiretroviral therapy (ART) drug substitutions are poorly described in resource-limited settings... - Initiation of highly active antiretroviral therapy among pregnant women in Cape Town, South AfricaKathryn Stinson
Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
Trop Med Int Health 15:825-32. 2010..To investigate highly active antiretroviral therapy (HAART) initiation among pregnant women and the optimum model of service delivery for integrating HAART services into antenatal care... - Outcomes after two years of providing antiretroviral treatment in Khayelitsha, South AfricaDavid Coetzee
Infectious Disease Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Anzio Road, Observatory 7925, South Africa
AIDS 18:887-95. 2004..With responsible implementation, ART is a key component of a comprehensive response to the epidemic in those communities most affected by HIV... - Immune activation in the female genital tract during HIV infection predicts mucosal CD4 depletion and HIV sheddingHeather B Jaspan
Institute of Infectious Disease and Molecular Medicine, Cape Town, South Africa
J Infect Dis 204:1550-6. 2011..These data suggest that the presence of high frequencies of activated T cells in the female genital mucosa during HIV infection facilitates both local HIV shedding and CD4 T-cell depletion... - Integrating tuberculosis and HIV care in the primary care setting in South AfricaDavid Coetzee
Infectious Disease Research Unit, School of Public Health and Family Medicine, University of Cape Town, Observatory, South Africa
Trop Med Int Health 9:A11-5. 2004.... - Isolation and characterization of T cells from semenAbraham J Olivier
Institute of Infectious Diseases and Molecular Medicine and Division of Medical Virology, University of Cape Town, Observatory 7925, Cape Town, South Africa
J Immunol Methods 375:223-31. 2012.... - Coverage of the prevention of mother-to-child transmission program in the Western Cape, South Africa using cord blood surveillanceKathryn Stinson
Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
J Acquir Immune Defic Syndr 60:199-204. 2012..Routine monitoring systems based on service data and limited to women on the PMTCT program may overestimate intervention coverage at multiple points along this cascade... - Genital human papillomavirus prevalence and human papillomavirus concordance in heterosexual couples are positively associated with human immunodeficiency virus coinfectionZizipho Z A Mbulawa
Institute of Infectious Disease and Molecular Medicine, 2School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, and 3National Health Laboratory Service, Groote Schuur Hospital, Cape Town, South Africa
J Infect Dis 199:1514-24. 2009..In conclusion, HIV coinfection in one or both sexually active partners increased HPV prevalence and HPV type-specific concordance... - Differences in antiretroviral scale up in three South African provinces: the role of implementation managementHelen Schneider
School of Public Health and Family Medicine, University of Cape Town, Anzio Road, Observatory, Cape Town 7925, South Africa
BMC Health Serv Res 10:S4. 2010.... - Impact of mucosal inflammation on cervical human immunodeficiency virus (HIV-1)-specific CD8 T-cell responses in the female genital tract during chronic HIV infectionPamela P Gumbi
Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, Cape Town, South Africa
J Virol 82:8529-36. 2008..In addition, we further show that inflammatory cytokines are associated with increased levels of HIV-specific CD8 effector cells at the genital mucosa but that these were not able to control genital HIV shedding... - Is the Western Cape at risk of an outbreak of preventable childhood diseases? Lessons from an evaluation of routine immunisation coverageJoanne Corrigall
School of Public Health, University of Cape Town
S Afr Med J 98:41-5. 2008..To determine the routine immunisation coverage rates in children aged 12 - 23 months in the Western Cape... - Monitoring effectiveness of programmes to prevent mother-to-child HIV transmission in lower-income countriesElizabeth M Stringer
Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
Bull World Health Organ 86:57-62. 2008..Finally, we propose a novel community survey-based approach that could be implemented widely throughout the developing world with minor modifications to ongoing Demographic and Health Surveys... - Implementation issues in tuberculosis/HIV program collaboration and integration: 3 case studiesGerald Friedland
AIDS Program, Section of Infectious Diseases, Department of Internal Medicine and Epidemiology, Yale University School of Medicine, New Haven, CT 06510, USA
J Infect Dis 196:S114-23. 2007..Conversely, smaller demonstration projects, even with successful outcomes, must grapple with issues related to generalization of findings, wider implementation, and scale up, to benefit larger populations of those in need... - Strengthening the health system and ensuring equity in the widescale implementation of an antiretroviral therapy programme in South AfricaHelen Schneider
S Afr Med J 93:772-3. 2003 - Regional differences in prevalence of HIV-1 discordance in Africa and enrollment of HIV-1 discordant couples into an HIV-1 prevention trialJairam R Lingappa
University of Washington, Department of Medicine, Seattle, Washington, USA
PLoS ONE 3:e1411. 2008..Substantial regional differences exist in HIV-1 prevalence in Africa, but regional differences in HIV-1 discordance among African couples, has not previously been reported... - Cohort profile: the paediatric antiretroviral treatment programmes in lower-income countries (KIDS-ART-LINC) collaborationElise Arrive
Unité INSERM 593, Institut de Santé Publique, Epidémiologie et Développement ISPED, Universite Victor Segalen, Bordeaux, France
Int J Epidemiol 37:474-80. 2008 - Sensitivity analysis and potential uses of a novel gamma interferon release assay for diagnosis of tuberculosisSimon J Tsiouris
Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 710, New York, NY 10032, USA
J Clin Microbiol 44:2844-50. 2006..The TST combined with IGRA or with a single sputum smear may have a role in excluding the diagnosis of TB in some settings...