Novel N Chegou

Summary

Affiliation: University of Stellenbosch
Country: South Africa

Publications

  1. pmc Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting
    Novel N Chegou
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa
    PLoS ONE 8:e64226. 2013
  2. pmc Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area
    Novel N Chegou
    Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa
    PLoS ONE 7:e38501. 2012
  3. pmc Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting
    Novel N Chegou
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Tygerberg 7505, South Africa
    BMC Infect Dis 12:10. 2012
  4. pmc Host markers in QuantiFERON supernatants differentiate active TB from latent TB infection: preliminary report
    Novel N Chegou
    Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, University of Stellenbosch, Cape Town, Western Cape Province, Tygerberg 7505, South Africa
    BMC Pulm Med 9:21. 2009
  5. doi request reprint Evaluation of adapted whole-blood interferon-gamma release assays for the diagnosis of pleural tuberculosis
    Novel N Chegou
    Department of Biomedical Sciences, Division of Molecular Biology and Human Genetics, DST NRF Centre of Excellence for Biomedical Tuberculosis Research, US MRC Centre for Molecular and Cellular Biology, Stellenbosch University, Cape Town, South Africa
    Respiration 76:131-8. 2008
  6. doi request reprint Tuberculosis assays: past, present and future
    Novel N Chegou
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, University of Stellenbosch, PO Box 19063, Francie van Zijl Drive, Tygerberg 7505, South Africa
    Expert Rev Anti Infect Ther 9:457-69. 2011
  7. doi request reprint Serodiagnostic markers for the prediction of the outcome of intensive phase tuberculosis therapy
    Ralf Baumann
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, P O Box 19063, Tygerberg 7505, South Africa
    Tuberculosis (Edinb) 93:239-45. 2013
  8. doi request reprint Differential cytokine/chemokines and KL-6 profiles in patients with different forms of tuberculosis
    Joel Fleury Djoba Siawaya
    Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences MRC Centre for Molecular and Cellular Biology DST and NRF Centre of Excellence for Biomedical TB Research, Stellenbosch University, South Africa
    Cytokine 47:132-6. 2009

Detail Information

Publications8

  1. pmc Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting
    Novel N Chegou
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa
    PLoS ONE 8:e64226. 2013
    ..tb) infection states. In this study, the utility of such markers was investigated in children screened for TB in a setting with high TB incidence...
  2. pmc Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area
    Novel N Chegou
    Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa
    PLoS ONE 7:e38501. 2012
    ..In this study, the levels of 11 host markers other than IFN-γ, were evaluated in whole blood culture supernatants after stimulation with M.tb infection phase-dependent antigens, for the diagnosis of TB disease...
  3. pmc Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting
    Novel N Chegou
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Tygerberg 7505, South Africa
    BMC Infect Dis 12:10. 2012
    ..tb infection states. In this study, we assessed the diagnostic potential of 118 different M.tb infection phase-dependent antigens in TB patients and household contacts (HHCs) in a high-burden setting...
  4. pmc Host markers in QuantiFERON supernatants differentiate active TB from latent TB infection: preliminary report
    Novel N Chegou
    Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, University of Stellenbosch, Cape Town, Western Cape Province, Tygerberg 7505, South Africa
    BMC Pulm Med 9:21. 2009
    ..These assays however, do not discriminate between latent TB infection (LTBI) and active TB disease...
  5. doi request reprint Evaluation of adapted whole-blood interferon-gamma release assays for the diagnosis of pleural tuberculosis
    Novel N Chegou
    Department of Biomedical Sciences, Division of Molecular Biology and Human Genetics, DST NRF Centre of Excellence for Biomedical Tuberculosis Research, US MRC Centre for Molecular and Cellular Biology, Stellenbosch University, Cape Town, South Africa
    Respiration 76:131-8. 2008
    ..Recently, in vitro interferon (IFN)-gamma-based assays have been introduced in the diagnosis of latent TB, but these techniques have not been established in the diagnosis of active TB disease, including pleural TB...
  6. doi request reprint Tuberculosis assays: past, present and future
    Novel N Chegou
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, University of Stellenbosch, PO Box 19063, Francie van Zijl Drive, Tygerberg 7505, South Africa
    Expert Rev Anti Infect Ther 9:457-69. 2011
    ..Host markers associated with active disease may hold promise, especially in situations where sputum diagnostics are problematic, including in children, HIV-infected individuals and in the case of extrapulmonary TB...
  7. doi request reprint Serodiagnostic markers for the prediction of the outcome of intensive phase tuberculosis therapy
    Ralf Baumann
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, P O Box 19063, Tygerberg 7505, South Africa
    Tuberculosis (Edinb) 93:239-45. 2013
    ..This approach holds promise and requires further evaluation for its utility in the prediction of treatment failure and relapse, the evaluation of new TB therapeutics, as well as in the care of individual patients...
  8. doi request reprint Differential cytokine/chemokines and KL-6 profiles in patients with different forms of tuberculosis
    Joel Fleury Djoba Siawaya
    Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences MRC Centre for Molecular and Cellular Biology DST and NRF Centre of Excellence for Biomedical TB Research, Stellenbosch University, South Africa
    Cytokine 47:132-6. 2009
    ..Plasma levels of cytokines may therefore contribute to biosignatures of diseases like TB but the data also highlight systemic differences between pulmonary TB, pleural TB and other form of pleural effusion diseases...