J A Carr

Summary

Affiliation: University of Stellenbosch
Country: South Africa

Publications

  1. doi A putative founder effect for Parkinson's disease in South African Afrikaners
    Jonathan Carr
    Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town, South Africa
    S Afr Med J 104:411-2. 2014
  2. pmc Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene
    Rowena J Keyser
    Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Cape Town, 8001, South Africa
    BMC Med Genet 10:105. 2009
  3. ncbi FAME 3: a novel form of progressive myoclonus and epilepsy
    J A Carr
    Division of Neurology, Faculty of Health Sciences, University of Stellenbosch, South Africa
    Neurology 68:1382-9. 2007
  4. doi Classifying myoclonus: a riddle, wrapped in a mystery, inside an enigma
    Jonathan Carr
    Division of Neurology, Faculty of Health Sciences, University of Stellenbosch, South Africa
    Parkinsonism Relat Disord 18:S174-6. 2012
  5. ncbi Early pubertal female rats are more resistant than males to 6-hydroxydopamine neurotoxicity and behavioural deficits: a possible role for trophic factors
    I S Pienaar
    Division of Medical Physiology, University of Stellenbosch, Western Cape, South Africa
    Restor Neurol Neurosci 25:513-26. 2007
  6. ncbi The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo
    J A L Ives
    Roche Products Ltd, 40 Broadwater Road, Welwyn Garden City, AL7 3AY, Hertfordshire, UK
    Antiviral Res 55:307-17. 2002
  7. ncbi Seasonal exposures to triazine and other pesticides in surface waters in the western Highveld corn-production region in South Africa
    L H Du Preez
    School of Environmental Sciences and Development, North West University, Potchefstroom Campus, Private Bag X6001, Potchefstroom 2520, South Africa
    Environ Pollut 135:131-41. 2005

Collaborators

Detail Information

Publications7

  1. doi A putative founder effect for Parkinson's disease in South African Afrikaners
    Jonathan Carr
    Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town, South Africa
    S Afr Med J 104:411-2. 2014
    ..Secondly, in the event that effective treatments are developed, particularly for presymptomatic patients, the Afrikaner population may be considered to be at risk and requiring careful assessment with accurate biomarkers. ..
  2. pmc Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene
    Rowena J Keyser
    Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Cape Town, 8001, South Africa
    BMC Med Genet 10:105. 2009
    ..In the present study South African PD patients were screened for mutations in DJ-1 and we aimed to investigate the functional significance of a novel 16 bp deletion variant identified in one patient...
  3. ncbi FAME 3: a novel form of progressive myoclonus and epilepsy
    J A Carr
    Division of Neurology, Faculty of Health Sciences, University of Stellenbosch, South Africa
    Neurology 68:1382-9. 2007
    ..Familial adult myoclonic epilepsy (FAME) is associated with myoclonus, tremor, and rare seizures, and is a nonprogressive disorder linked to the FAME 1 locus. A similar disorder has been linked to the FAME 2 locus...
  4. doi Classifying myoclonus: a riddle, wrapped in a mystery, inside an enigma
    Jonathan Carr
    Division of Neurology, Faculty of Health Sciences, University of Stellenbosch, South Africa
    Parkinsonism Relat Disord 18:S174-6. 2012
    ..The role of subcortical structures in influencing electrophysiological phenomena is poorly understood, and merits further investigation...
  5. ncbi Early pubertal female rats are more resistant than males to 6-hydroxydopamine neurotoxicity and behavioural deficits: a possible role for trophic factors
    I S Pienaar
    Division of Medical Physiology, University of Stellenbosch, Western Cape, South Africa
    Restor Neurol Neurosci 25:513-26. 2007
    ..The present study focused on possible gender differences in vulnerability to 6-OHDA during the early pubertal period when the effects exerted by gonadal steroid hormones are unpronounced...
  6. ncbi The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo
    J A L Ives
    Roche Products Ltd, 40 Broadwater Road, Welwyn Garden City, AL7 3AY, Hertfordshire, UK
    Antiviral Res 55:307-17. 2002
    ..Additionally, pathogenicity of the mutant virus is significantly compromised in ferret, compared to the corresponding wild type virus. Virus carrying a H274Y mutation is unlikely to be of clinical consequence in man...
  7. ncbi Seasonal exposures to triazine and other pesticides in surface waters in the western Highveld corn-production region in South Africa
    L H Du Preez
    School of Environmental Sciences and Development, North West University, Potchefstroom Campus, Private Bag X6001, Potchefstroom 2520, South Africa
    Environ Pollut 135:131-41. 2005
    ..Because of dilution by higher than normal rainfall in the study period, these concentrations may not be predictive of those in years of normal rainfall...