Hoosen Coovadia

Summary

Affiliation: Reproductive Health and HIV Research Unit
Country: South Africa

Publications

  1. pmc HIV-1 subtype C envelope characteristics associated with divergent rates of chronic disease progression
    Derseree Archary
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R, Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Retrovirology 7:92. 2010
  2. doi The health and health system of South Africa: historical roots of current public health challenges
    Hoosen Coovadia
    Nelson Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Lancet 374:817-34. 2009
  3. pmc Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection
    Christina F Thobakgale
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu Natal, Durban, South Africa
    J Virol 83:10234-44. 2009
  4. pmc Efficacy and safety of an extended nevirapine regimen in infants of breastfeeding mothers with HIV-1 infection for prevention of HIV-1 transmission (HPTN 046): 18-month results of a randomized, double-blind, placebo-controlled trial
    Mary Glenn Fowler
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD Maternal Adolescent and Child Health, University of the Witwatersrand, South Africa Fred Hutchinson Cancer Research Center, Seattle, WA Department of Pediatrics, Stanford University School of Medicine, Stanford, CA Department of Obstetrics and Gynecology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa Makerere University, Johns Hopkins University, Research Collaboration, Kampala, Uganda Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania Department of Pediatrics, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe Department of Global Health and Population, Harvard University School of Public Health, Boston, MA Family Health International, Research Triangle Park, NC Division of HIV AIDS, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, MD and Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD
    J Acquir Immune Defic Syndr 65:366-74. 2014
  5. doi Women's morbidity and mortality in the first 2 years after delivery according to HIV status
    Anna Coutsoudis
    Department of Paediatrics and Child Health, University of KwaZulu Natal, Durban, South Africa
    AIDS 24:2859-66. 2010
  6. doi Breastfeeding, HIV status and weights in South African children: a comparison of HIV-exposed and unexposed children
    Deven Patel
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, KwaZulu Natal 3935, South Africa
    AIDS 24:437-45. 2010
  7. ncbi Short communication: CD4 counts of HIV-infected pregnant women and their infected children--implications for PMTCT and treatment programmes
    Ankie Lebon
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
    Trop Med Int Health 12:1472-4. 2007
  8. pmc Human immunodeficiency virus-specific CD8+ T-cell activity is detectable from birth in the majority of in utero-infected infants
    Christina F Thobakgale
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu Natal, Durban, South Africa
    J Virol 81:12775-84. 2007
  9. pmc HIV disease progression in the first year after delivery among African women followed in the HPTN 046 clinical trial
    D Heather Watts
    Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD Fred Hutchinson Cancer Research Center, Seattle, WA Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA University of Zimbabwe College of Medicine, Harare, Zimbabwe Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa Makerere University Johns Hopkins University Research Collaboration, Kampala, Uganda Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania Harvard School of Public Health, Boston, MA Family Health International, Research Triangle Park, Chapel Hill, NC Johns Hopkins Medical Institutes, Baltimore, MD National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD Maternal Adolescent and Child Health, University of the Witwatersrand, Johannesburg, South Africa, and Statistical Center for HIV AIDS Research and Prevention SCHARP, Seattle, WA
    J Acquir Immune Defic Syndr 64:299-306. 2013
  10. doi Current issues in prevention of mother-to-child transmission of HIV-1
    Hoosen Coovadia
    Doris Duke Medical Research Institute, Nelson Mandela School of Medicine, University of KwaZulu Natal, 719 Umbilo Road, Congella, South Africa 4013, South Africa
    Curr Opin HIV AIDS 4:319-24. 2009

Collaborators

Detail Information

Publications16

  1. pmc HIV-1 subtype C envelope characteristics associated with divergent rates of chronic disease progression
    Derseree Archary
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R, Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Retrovirology 7:92. 2010
    ..5 months...
  2. doi The health and health system of South Africa: historical roots of current public health challenges
    Hoosen Coovadia
    Nelson Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Lancet 374:817-34. 2009
    ..The HIV epidemic has contributed to and accelerated these challenges. All of these factors need to be addressed by the new government if health is to be improved and the Millennium Development Goals achieved in South Africa...
  3. pmc Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection
    Christina F Thobakgale
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu Natal, Durban, South Africa
    J Virol 83:10234-44. 2009
    ....
  4. pmc Efficacy and safety of an extended nevirapine regimen in infants of breastfeeding mothers with HIV-1 infection for prevention of HIV-1 transmission (HPTN 046): 18-month results of a randomized, double-blind, placebo-controlled trial
    Mary Glenn Fowler
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD Maternal Adolescent and Child Health, University of the Witwatersrand, South Africa Fred Hutchinson Cancer Research Center, Seattle, WA Department of Pediatrics, Stanford University School of Medicine, Stanford, CA Department of Obstetrics and Gynecology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa Makerere University, Johns Hopkins University, Research Collaboration, Kampala, Uganda Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania Department of Pediatrics, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe Department of Global Health and Population, Harvard University School of Public Health, Boston, MA Family Health International, Research Triangle Park, NC Division of HIV AIDS, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, MD and Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD
    J Acquir Immune Defic Syndr 65:366-74. 2014
    ..HPTN 046 compared the efficacy and safety of infant nevirapine (NVP) among HIV-exposed breastfed infants randomized at 6 weeks to 6 months to t NVP or placebo to prevent postnatal infection: we report final 18-month outcomes...
  5. doi Women's morbidity and mortality in the first 2 years after delivery according to HIV status
    Anna Coutsoudis
    Department of Paediatrics and Child Health, University of KwaZulu Natal, Durban, South Africa
    AIDS 24:2859-66. 2010
    ..Better knowledge of the impact of HIV status on morbidity and mortality patterns of women after delivery is important to improve clinical and policy recommendations...
  6. doi Breastfeeding, HIV status and weights in South African children: a comparison of HIV-exposed and unexposed children
    Deven Patel
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, KwaZulu Natal 3935, South Africa
    AIDS 24:437-45. 2010
    ..To examine growth of children by maternal and infant HIV status allowing for infant feeding mode...
  7. ncbi Short communication: CD4 counts of HIV-infected pregnant women and their infected children--implications for PMTCT and treatment programmes
    Ankie Lebon
    Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
    Trop Med Int Health 12:1472-4. 2007
    ..The antenatal-postnatal divide needs to be bridged with respect to the follow-up of both HIV-infected women and their exposed infants...
  8. pmc Human immunodeficiency virus-specific CD8+ T-cell activity is detectable from birth in the majority of in utero-infected infants
    Christina F Thobakgale
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu Natal, Durban, South Africa
    J Virol 81:12775-84. 2007
    ..Moreover, the detection of virus-specific CD8+ T-cell responses in the first days of life in most in utero-infected infants is encouraging for HIV vaccine interventions in infants...
  9. pmc HIV disease progression in the first year after delivery among African women followed in the HPTN 046 clinical trial
    D Heather Watts
    Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD Fred Hutchinson Cancer Research Center, Seattle, WA Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA University of Zimbabwe College of Medicine, Harare, Zimbabwe Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa Makerere University Johns Hopkins University Research Collaboration, Kampala, Uganda Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania Harvard School of Public Health, Boston, MA Family Health International, Research Triangle Park, Chapel Hill, NC Johns Hopkins Medical Institutes, Baltimore, MD National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD Maternal Adolescent and Child Health, University of the Witwatersrand, Johannesburg, South Africa, and Statistical Center for HIV AIDS Research and Prevention SCHARP, Seattle, WA
    J Acquir Immune Defic Syndr 64:299-306. 2013
    ..We evaluated disease progression among HIV-infected women not on ART with CD4⁺ lymphocyte counts above 200 cells per microliter at delivery...
  10. doi Current issues in prevention of mother-to-child transmission of HIV-1
    Hoosen Coovadia
    Doris Duke Medical Research Institute, Nelson Mandela School of Medicine, University of KwaZulu Natal, 719 Umbilo Road, Congella, South Africa 4013, South Africa
    Curr Opin HIV AIDS 4:319-24. 2009
    ..To review new evidence in prevention of mother-to-child-transmission of HIV-1, which establishes, in principle, the feasibility of greatly improved effectiveness in developing countries...
  11. doi From Alma-Ata to Agincourt: primary health care in AIDS
    Hoosen Coovadia
    University of KwaZulu Natal, Durban, Kwazulu Natal 4013, South Africa
    Lancet 372:866-8. 2008
  12. doi Science and society: the HIV epidemic and South African political responses
    Hoosen Coovadia
    Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Adv Exp Med Biol 609:16-28. 2008
  13. pmc Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in South Africa
    Taryn N Green
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu Natal, Durban, South Africa
    AIDS Res Hum Retroviruses 28:324-32. 2012
    ..Enhanced genotypic prediction tools are needed as current tools are not sensitive enough for predicting CXCR4 usage...
  14. ncbi CD8+ T-cell responses to different HIV proteins have discordant associations with viral load
    Photini Kiepiela
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu Natal, Durban 4013, South Africa
    Nat Med 13:46-53. 2007
    ..These population-based data, suggesting the existence of both effective immune responses and responses lacking demonstrable biological impact in chronic HIV infection, are of relevance to HIV vaccine design and evaluation...
  15. ncbi Prevention of transmission of HIV-1 from mothers to infants in Africa
    Hoosen Coovadia
    Centre for HIV and AIDS Networking, University of KwaZulu Natal, Nelson R Mandela School of Medicine, Doris Duke Medical Research Institute, Congella, Durban, South Africa
    Adv Exp Med Biol 582:201-20. 2006
  16. ncbi Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: a randomised double-blind placebo-controlled trial
    Raziya Bobat
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Lancet 366:1862-7. 2005
    ..However, in children with HIV-1 infection, the safety of zinc supplementation is uncertain. We aimed to assess the role of zinc in HIV-1 replication before mass zinc supplementation is recommended in regions of high HIV-1 prevalence...