Research Topics
| Cheryl CohenSummaryAffiliation: National Institute for Communicable Diseases Country: South Africa Publications
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Detail Information
Publications
Influenza-related mortality among adults aged 25-54 years with AIDS in South Africa and the United States of AmericaCheryl Cohen
National Institute for Communicable Diseases of the National Health Laboratory Service, University of the Witwatersrand, Johannesburg, South Africa
Clin Infect Dis 55:996-1003. 2012..We compared influenza-related mortality in adults with AIDS in South Africa and the United States in the pre-HAART era and evaluated mortality trends after HAART introduction in the United States...
Vaccine effectiveness estimates, 2004-2005 mumps outbreak, EnglandCheryl Cohen
National Institute for Communicable Diseases, Johannesburg, South Africa
Emerg Infect Dis 13:12-7. 2007..5%) in 5- to 6-year-olds to 86% (95% CI 74%-93%) in 11- to 12-year-olds (p<0.001 for 1 or 2 doses). Waning immunity may contribute to mumps outbreaks in older vaccinated populations...- Epidemiology and molecular virus characterization of reemerging rabies, South AfricaCheryl Cohen
National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa
Emerg Infect Dis 13:1879-86. 2007..Delayed recognition of the human cases may have resulted from decreased clinical suspicion after many years of effective control of the disease and the occurrence of atypical clinical presentations... - Elevated influenza-related excess mortality in South African elderly individuals, 1998-2005Cheryl Cohen
National Institute for Communicable Diseases of the National Health Laboratory Service, South Africa
Clin Infect Dis 51:1362-9. 2010..We aimed to compare influenza-related mortality among individuals aged ≥65 years in South Africa and the United States... - Increased incidence of meningococcal disease in HIV-infected individuals associated with higher case-fatality ratios in South AfricaCheryl Cohen
National Institute for Communicable Diseases, Johannesburg, South Africa
AIDS 24:1351-60. 2010..We aimed to compare the incidence of meningococcal disease amongst HIV-infected and uninfected individuals and to evaluate whether HIV is a risk factor for mortality and bacteremia amongst patients with meningococcal disease... - An unusual pneumococcal sequence type is the predominant cause of serotype 3 invasive disease in South AfricaKedibone M Mothibeli
Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases, Medical Research Council, University of the Witwatersrand, Johannesburg, South Africa
J Clin Microbiol 48:184-91. 2010..We have therefore identified ST458 as predominating in South Africa, but with an invasive potential similar to that of the predominant global clone ST180... - Neisseria meningitidis intermediately resistant to penicillin and causing invasive disease in South Africa in 2001 to 2005Mignon du Plessis
National Institute for Communicable Diseases of the National Health Laboratory Service, University of the Witwatersrand, Johannesburg, South Africa
J Clin Microbiol 46:3208-14. 2008..This is the first report describing the prevalence and molecular epidemiology of Pen(i) meningococcal isolates from sub-Saharan Africa... - Serotype 6C is associated with penicillin-susceptible meningeal infections in human immunodeficiency virus (HIV)-infected adults among invasive pneumococcal isolates previously identified as serotype 6A in South AfricaMignon du Plessis
National Institute for Communicable Diseases, Sandringham, South Africa
Int J Antimicrob Agents 32:S66-70. 2008..Our data from the vaccine efficacy trial suggest that cross-protection of the conjugate vaccine is against true serotype 6A strains... - Emergence of levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance studyAnne Von Gottberg
National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa
Lancet 371:1108-13. 2008..Our aim was to estimate the incidence of, and risk factors for, invasive pneumococcal disease caused by fluoroquinolone-resistant Streptococcus pneumoniae in children in South Africa... - The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysisMarta C Nunes
Medical Research Council Respiratory and Meningeal Pathogens Research Unit and Department of Science and Technology National Research Foundation Vaccine Preventable Diseases, University of the Witwatersrand, South Africa
AIDS 25:453-62. 2011..A national antiretroviral program was initiated in South Africa in 2004. This study evaluates the impact of the highly active antiretroviral therapy (HAART) treatment program on the burden of IPD among African children... - Evolutionary dynamics of 2009 pandemic influenza A virus subtype H1N1 in South Africa during 2009-2010Marietjie Venter
National Institute for Communicable Diseases Division, National Health Laboratory Service, Department of Medical Virology, University of Pretoria, Johannesburg, South Africa
J Infect Dis 206:S166-72. 2012.... - Persistent high burden of invasive pneumococcal disease in South African HIV-infected adults in the era of an antiretroviral treatment programMarta C Nunes
Department of Science and Technology National Research Foundation, Vaccine Preventable Diseases and Medical Research Council, Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
PLoS ONE 6:e27929. 2011..The aim of this study was to evaluate trends in IPD hospitalizations in HIV-infected adults in Soweto, South Africa, associated with up-scaling of the HAART program from 2003 to 2008... - Introduction of pneumococcal conjugate vaccine into the public immunization program in South Africa: translating research into policyShabir A Madhi
National Institute for Communicable Diseases, A Division of the National Health Laboratory Service, Johannesburg, South Africa
Vaccine 30:C21-7. 2012..This schedule was largely premised on containing the cost of vaccine introduction, whilst including a booster dose of PCV to assist in prolonging the duration of protection in HIV-infected children... - Risk factors for multidrug-resistant invasive pneumococcal disease in South Africa, a setting with high HIV prevalence, in the prevaccine era from 2003 to 2008Penny Crowther-Gibson
Division of Public Health Surveillance and Response, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa
Antimicrob Agents Chemother 56:5088-95. 2012..The effect of many of the MDR risk factors could be reduced by more judicious use of antibiotics. Because PCV13 serotypes account for most MDR infections, pneumococcal vaccination may reduce the prevalence of multidrug resistance... - Molecular basis and clonal nature of increasing pneumococcal macrolide resistance in South Africa, 2000-2005Nicole Wolter
Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases, Medical Research Council and University of the Witwatersrand, Sandringham, South Africa
Int J Antimicrob Agents 32:62-7. 2008..Routine use of the 7-valent pneumococcal conjugate vaccine (PCV-7) could reduce the burden of macrolide-resistant pneumococcal disease in South Africa... - Emergence of endemic serogroup W135 meningococcal disease associated with a high mortality rate in South AfricaAnne Von Gottberg
Respiratory and Meningeal Pathogens Research, National Institute for Communicable Diseases, Private Bag X4, Sandringham, 2131, Gauteng, South Africa
Clin Infect Dis 46:377-86. 2008..In the African meningitis belt, Neisseria meningitidis serogroup W135 has emerged as a cause of epidemic disease. The establishment of W135 as the predominant cause of endemic disease has not been described... - Respiratory viral coinfections identified by a 10-plex real-time reverse-transcription polymerase chain reaction assay in patients hospitalized with severe acute respiratory illness--South Africa, 2009-2010Marthi A Pretorius
National Institute for Communicable Diseases, National Health Laboratory Service, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
J Infect Dis 206:S159-65. 2012.... - Invasive disease due to Haemophilus influenzae serotype b ten years after routine vaccination, South Africa, 2003-2009Anne Von Gottberg
National Institute for Communicable Diseases NICD of the National Health Laboratory Service NHLS, Johannesburg, South Africa
Vaccine 30:565-71. 2012..Following initial declines in Hib disease, national surveillance has identified increasing numbers of Hib disease episodes in fully vaccinated children... - Measles outbreak in South Africa: epidemiology of laboratory-confirmed measles cases and assessment of intervention, 2009-2011Genevie M Ntshoe
Centre for Vaccines and Immunology, National Institute for Communicable Diseases NICD of the National Health Laboratory Service NHLS, Johannesburg, South Africa
PLoS ONE 8:e55682. 2013..We describe the epidemiology of laboratory-confirmed measles case-patients and assess the impact of the nationwide mass vaccination campaign during the 2009 to 2011 measles outbreak in South Africa... - Systemic shigellosis in South AfricaKaren H Keddy
Centre for Enteric Diseases, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa
Clin Infect Dis 54:1448-54. 2012..We examined the clinical and microbiologic characteristics of systemic shigellosis in South Africa, where rates of HIV infection are high... - Increased risk of death in human immunodeficiency virus-infected children with pneumococcal meningitis in South Africa, 2003-2005Peter Nyasulu
School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Pediatr Infect Dis J 30:1075-80. 2011..Pneumococcal disease is a major global cause of morbidity and mortality. This study evaluated risk factors for mortality in children with pneumococcal meningitis and other invasive pneumococcal diseases (IPD)... 
Analysis of a temporal cluster of Shigella boydii isolates in Mpumalanga, South Africa, November to December 2007Anthony M Smith
National Institute for Communicable Diseases, Johannesburg
J Infect Dev Ctries 3:65-70. 2009..In the present study, we report on the analysis of a temporal cluster of 29 S. boydii serotype 2 strains, isolated in the Mpumalanga Province of South Africa (SA) over the period of November to December 2007...- A comparison of cases of paediatric-onset and adult-onset cryptococcosis detected through population-based surveillance, 2005-2007Susan T Meiring
National Institute for Communicable Diseases, National Health Laboratory Service, Sandringham, South Africa
AIDS 26:2307-14. 2012..We compared the epidemiology of laboratory-confirmed paediatric cryptococcal disease with adult-onset disease in the South African population... - Twenty-five years of outpatient influenza surveillance in South Africa, 1984-2008Johanna M McAnerney
National Institute for Communicable Diseases of the National Health Laboratory Services, Johannesburg, South Africa
J Infect Dis 206:S153-8. 2012..The aim of this manuscript is to describe the trends and epidemiology of outpatient influenza in South Africa prior to the influenza A(H1N1) pandemic... - Increased prevalence of severe malaria in HIV-infected adults in South AfricaCheryl Cohen
Division of Clinical Microbiology and Infectious Diseases, University of the Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa
Clin Infect Dis 41:1631-7. 2005..248). CONCLUSIONS: HIV-infected nonimmune adults are at increased risk of severe malaria. This risk is associated with a low CD4+ T cell count. This interaction is of great public health importance... - Introduction of 2009 pandemic influenza A virus subtype H1N1 into South Africa: clinical presentation, epidemiology, and transmissibility of the first 100 casesBrett N Archer
National Institute for Communicable Diseases, National Health Laboratory Service, University of Witwatersrand, Johannesburg, South Africa
J Infect Dis 206:S148-53. 2012..We documented the introduction of 2009 pandemic influenza A virus subtype H1N1 (A[H1N1]pdm09) into South Africa and describe its clinical presentation, epidemiology, and transmissibility... - Nosocomial outbreak of novel arenavirus infection, southern AfricaJanusz T Paweska
National Institute for Communicable Diseases, Sandringham, South Africa
Emerg Infect Dis 15:1598-602. 2009..Three cases involved secondary spread of infection from the first patient, and 1 was a tertiary infection. A novel arenavirus was identified. The source of the first patient's infection remains undetermined... - Cryptococcosis in Gauteng: implications for monitoring of HIV treatment programmesKerrigan M McCarthy
S Afr Med J 98:452, 454. 2008