Gita Ramjee

Summary

Affiliation: Medical Research Council
Country: South Africa

Publications

  1. ncbi request reprint The impact of incident and prevalent herpes simplex virus-2 infection on the incidence of HIV-1 infection among commercial sex workers in South Africa
    Gita Ramjee
    HIV 1 Prevention Research Unit, Medical Research Council, Durban, South Africa
    J Acquir Immune Defic Syndr 39:333-9. 2005
  2. ncbi request reprint Prevalence of HIV among truck drivers visiting sex workers in KwaZulu-Natal, South Africa
    Gita Ramjee
    HIV Prevention and Vaccine Research Division, Medical Research Council, Durban, South Africa
    Sex Transm Dis 29:44-9. 2002
  3. pmc South Africa's experience of the closure of the cellulose sulphate microbicide trial
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, Durban, KwaZulu Natal, South Africa
    PLoS Med 4:e235. 2007
  4. pmc The diaphragm and lubricant gel for prevention of cervical sexually transmitted infections: results of a randomized controlled trial
    Gita Ramjee
    Medical Research Council, Durban, South Africa
    PLoS ONE 3:e3488. 2008
  5. ncbi request reprint The value of site preparedness studies for future implementation of phase 2/IIb/III HIV prevention trials: experience from the HPTN 055 study
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, Overport, Durban, South Africa
    J Acquir Immune Defic Syndr 47:93-100. 2008
  6. pmc Geographical clustering of high risk sexual behaviors in "hot-spots" for HIV and sexually transmitted infections in Kwazulu-Natal, South Africa
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, 123 Jan Hofmeyr Road, Westville, Durban, South Africa
    AIDS Behav 18:317-22. 2014
  7. pmc HIV incidence among non-pregnant women living in selected rural, semi-rural and urban areas in KwaZulu-Natal, South Africa
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, 123 Jan Hofmeyr Road, Westville, Durban 3630, South Africa
    AIDS Behav 16:2062-71. 2012
  8. pmc Population-level impact of hormonal contraception on incidence of HIV infection and pregnancy in women in Durban, South Africa
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, 123 Jan Hofmeyr Road, Westville, Durban, 3630, South Africa
    Bull World Health Organ 90:748-55. 2012
  9. ncbi request reprint Incidence of Sexually Transmitted Infections among HIV-positive sex workers in KwaZulu-Natal, South Africa
    Catherine A Connolly
    Biostatistics Unit, Medical Research Council, Durban, South Africa
    Sex Transm Dis 29:721-4. 2002
  10. pmc A developing country response to Lavery et al. "In global health research, is it legitimate to stop clinical trials early on account of their opportunity costs?"
    Douglas R Wassenaar
    Biomedical Research Ethics Committee, University of KwaZulu Natal, Durban, South Africa
    BMC Med Ethics 10:16. 2009

Collaborators

Detail Information

Publications34

  1. ncbi request reprint The impact of incident and prevalent herpes simplex virus-2 infection on the incidence of HIV-1 infection among commercial sex workers in South Africa
    Gita Ramjee
    HIV 1 Prevention Research Unit, Medical Research Council, Durban, South Africa
    J Acquir Immune Defic Syndr 39:333-9. 2005
    ..Drawing on other recent studies these data suggest that incident HSV-2 infection increases the risk of HIV-1 infection; the effect wanes with time since infection; and the effect is significantly greater for men than it is for women...
  2. ncbi request reprint Prevalence of HIV among truck drivers visiting sex workers in KwaZulu-Natal, South Africa
    Gita Ramjee
    HIV Prevention and Vaccine Research Division, Medical Research Council, Durban, South Africa
    Sex Transm Dis 29:44-9. 2002
    ..Although the role of mobile populations in the spread of HIV has been documented in several countries, there are few data on HIV among truck drivers in South Africa and the sex workers with whom they interact...
  3. pmc South Africa's experience of the closure of the cellulose sulphate microbicide trial
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, Durban, KwaZulu Natal, South Africa
    PLoS Med 4:e235. 2007
  4. pmc The diaphragm and lubricant gel for prevention of cervical sexually transmitted infections: results of a randomized controlled trial
    Gita Ramjee
    Medical Research Council, Durban, South Africa
    PLoS ONE 3:e3488. 2008
    ....
  5. ncbi request reprint The value of site preparedness studies for future implementation of phase 2/IIb/III HIV prevention trials: experience from the HPTN 055 study
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, Overport, Durban, South Africa
    J Acquir Immune Defic Syndr 47:93-100. 2008
    ..To evaluate the preparedness for phase 2/IIb/III microbicide trials at 4 clinical trial sites: Durban and Hlabisa (South Africa), Lusaka (Zambia), and Moshi (Tanzania)...
  6. pmc Geographical clustering of high risk sexual behaviors in "hot-spots" for HIV and sexually transmitted infections in Kwazulu-Natal, South Africa
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, 123 Jan Hofmeyr Road, Westville, Durban, South Africa
    AIDS Behav 18:317-22. 2014
    ....
  7. pmc HIV incidence among non-pregnant women living in selected rural, semi-rural and urban areas in KwaZulu-Natal, South Africa
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, 123 Jan Hofmeyr Road, Westville, Durban 3630, South Africa
    AIDS Behav 16:2062-71. 2012
    ..The epidemic in KwaZulu-Natal calls for targeted HIV prevention interventions among those at highest risk of acquiring or transmitting infection...
  8. pmc Population-level impact of hormonal contraception on incidence of HIV infection and pregnancy in women in Durban, South Africa
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, 123 Jan Hofmeyr Road, Westville, Durban, 3630, South Africa
    Bull World Health Organ 90:748-55. 2012
    ..To estimate the potential impact of using hormonal contraceptives on rates of infection with human immunodeficiency virus type 1 (HIV-1) and pregnancy by theoretically removing the use of hormonal contraceptives from a study population...
  9. ncbi request reprint Incidence of Sexually Transmitted Infections among HIV-positive sex workers in KwaZulu-Natal, South Africa
    Catherine A Connolly
    Biostatistics Unit, Medical Research Council, Durban, South Africa
    Sex Transm Dis 29:721-4. 2002
    ..However, the success of such programs among HIV-positive sex workers has not been shown. GOAL The goal of the study was to determine the incidence of STIs ( and infections) among HIV-positive sex workers...
  10. pmc A developing country response to Lavery et al. "In global health research, is it legitimate to stop clinical trials early on account of their opportunity costs?"
    Douglas R Wassenaar
    Biomedical Research Ethics Committee, University of KwaZulu Natal, Durban, South Africa
    BMC Med Ethics 10:16. 2009
    ..A recent paper presents an argument and mechanism for the possible stopping of clinical trials early based on opportunity costs...
  11. doi request reprint Novel strategies implemented to ensure high participant retention rates in a community based HIV prevention effectiveness trial in South Africa and Zimbabwe
    Sharika Gappoo
    HIV Prevention Research Unit, Medical Research Council, South Africa
    Contemp Clin Trials 30:411-8. 2009
    ....
  12. pmc Microbicides for HIV prevention
    Gita Ramjee
    Medical Research Council, Durban, South Africa
    Indian J Med Res 134:930-8. 2011
    ....
  13. pmc Experiences in conducting multiple community-based HIV prevention trials among women in KwaZulu-Natal, South Africa
    Gita Ramjee
    HIV Prevention Research Unit, South African Medical Research Council, 123 Jan Hofmeyr Road, Westville, 3630, Durban, South Africa
    AIDS Res Ther 7:10. 2010
    ..The critical mass of scientists trained as clinical trialists will continue to address the relentless HIV epidemic in our setting and ensure our commitment to finding a biomedical HIV prevention option for women in the future...
  14. ncbi request reprint Microbicide research: current and future directions
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, Durban, South Africa
    Curr Opin HIV AIDS 5:316-21. 2010
    ..This review takes into consideration clinical, basic scientific and behavioural research published on microbicides in the past 12-18 months...
  15. pmc High risk sexual behaviors are associated with sexual violence among a cohort of women in Durban, South Africa
    Zakir Gaffoor
    HIV Prevention Research Unit, Medical Research Council, Durban, South Africa
    BMC Res Notes 6:532. 2013
    ..This study describes the prevalence of Forced Sex (FS) experiences of women who enrolled into an HIV biomedical intervention study, and its association with risky sexual behaviour...
  16. doi request reprint The last decade of microbicide clinical trials in Africa: from hypothesis to facts
    Gita Ramjee
    HIV Prevention Research Unit, Medical Research Council, Durban, South Africa
    AIDS 24:S40-9. 2010
    ..PrEP for vaginal administration in various formulations is being tested to continue our commitment to providing more HIV prevention options to millions of women worldwide...
  17. pmc Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: a randomised controlled trial
    Nancy S Padian
    University of California, San Francisco, CA, USA
    Lancet 370:251-61. 2007
    ..We assessed the effect of provision of latex diaphragm, lubricant gel, and condoms (intervention), compared with condoms alone (control) on HIV seroincidence in women in South Africa and Zimbabwe...
  18. pmc Regional clustering of shared neutralization determinants on primary isolates of clade C human immunodeficiency virus type 1 from South Africa
    Renata Bures
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Virol 76:2233-44. 2002
    ..The clustering of shared neutralization determinants on clade C primary HIV-1 isolates from South Africa suggests that neutralizing antibodies induced by vaccines will have less epitope diversity to overcome at a regional level...
  19. ncbi request reprint Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial
    Lut Van Damme
    Institute of Tropical Medicine, Antwerp, Belgium
    Lancet 360:971-7. 2002
    ..Results of studies of its effectiveness in prevention of HIV-1 infection in women have been inconclusive. We aimed to assess effectiveness of this vaginal gel...
  20. ncbi request reprint Response to Brown et al., 'Incident and prevalent herpes simplex virus type 2 infection increases risk of HIV acquisition among women in Uganda and Zimbabwe'
    Brian G Williams
    AIDS 21:2356-7. 2007
  21. pmc "We have our protector": misperceptions of protection against HIV among participants in a microbicide efficacy trial
    Joanne E Mantell
    MSPH, HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, NY, USA
    Am J Public Health 96:1073-7. 2006
    ..We examined perceptions of the effectiveness and acceptability of a candidate microbicide among 94 South African female sex workers who had participated in a phase 3 microbicide trial for HIV prevention...
  22. doi request reprint Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission
    Lut Van Damme
    CONRAD, Arlington, VA, USA
    N Engl J Med 359:463-72. 2008
    ..Women make up more than 50% of adults living with human immunodeficiency virus (HIV) infection or the acquired immunodeficiency syndrome (AIDS) in sub-Saharan Africa. Thus, female-initiated HIV prevention methods are urgently needed...
  23. ncbi request reprint The impact of the use of COL-1492, a nonoxynol-9 vaginal gel, on the presence of cervical human papillomavirus in female sex workers
    Dianne Marais
    Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, South Africa
    Virus Res 121:220-2. 2006
    ..5 95% CI 1.0-11.8). We conclude that the use of nonoxynol-9 did not prevent genital HPV infection and could increase the virus' ability to infect or persist...
  24. doi request reprint Provision of antiretroviral therapy in South Africa: unique challenges and remaining obstacles
    Bisola Ojikutu
    Division of AIDS, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Infect Dis 196:S523-7. 2007
    ....
  25. ncbi request reprint Nonoxynol-9 spermicide for prevention of vaginally acquired HIV and other sexually transmitted infections: systematic review and meta-analysis of randomised controlled trials including more than 5000 women
    David Wilkinson
    Division of Health Sciences, University of South Australia, Adelaide, Australia
    Lancet Infect Dis 2:613-7. 2002
    ..There is some evidence of harm through genital lesions. N-9 cannot be recommended for HIV and STI prevention...
  26. ncbi request reprint Carraguard Vaginal Gel Safety in HIV-Positive Women and Men in South Africa
    Janneke H H M van de Wijgert
    Population Council, New York, NY, USA
    J Acquir Immune Defic Syndr 46:538-46. 2007
    ..To assess the safety of the candidate microbicide Carraguard gel in HIV-positive women and men...
  27. ncbi request reprint Characterization and selection of HIV-1 subtype C isolates for use in vaccine development
    Carolyn Williamson
    Division of Medical Virology, University of Cape Town, Observatory, Cape Town, South Africa 7925
    AIDS Res Hum Retroviruses 19:133-44. 2003
    ..Genes identified in this study have been incorporated into the VEE VRP candidate vaccines targeted for clinical trial in South Africa...
  28. doi request reprint Microbicide acceptability: insights for future directions from providers and policy makers
    Susie Hoffman
    HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, New York, NY 10032, USA
    AIDS Educ Prev 20:188-202. 2008
    ..Developing these approaches will maximize the positive influence that providers can exert on user acceptability of microbicides once they become available...
  29. ncbi request reprint Incidence of HIV-1 dual infection and its association with increased viral load set point in a cohort of HIV-1 subtype C-infected female sex workers
    Jandre Grobler
    Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, University of Cape Town, Observatory, South Africa
    J Infect Dis 190:1355-9. 2004
    ..There was a significant association between dual infection and elevated viral load set point...
  30. ncbi request reprint Microbicide acceptability research: current approaches and future directions
    Joanne E Mantell
    HIV Center for Clinical and Behavioral Studies, at the New York State Psychiatric Institute and Columbia University, 1051 Riverside Drive, Unit 15, New York, NY 10032, USA
    Soc Sci Med 60:319-30. 2005
    ..Failure to understand the key factors associated with microbicide acceptability is likely to hinder the adoption and continued use of products that are effective in preventing HIV infection...
  31. ncbi request reprint Longitudinal analysis of HIV type 1 subtype C envelope sequences from South Africa
    Mia Coetzer
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Sandringham 2131, Johannesburg, South Africa
    AIDS Res Hum Retroviruses 23:316-21. 2007
    ..In both cases this coreceptor switch was associated with specific amino acid changes in the crown, an increased net amino acid charge in the V3 loop, and an increase in the length of the V1 region...
  32. ncbi request reprint Heterosexual transmission of multiple highly conserved viral variants in HIV-1 subtype C-infected seronegative women
    Cecilia Rademeyer
    Institute of Infectious Diseases and Molecular Medicine, Division of Medical Virology, University of Cape Town, Observatory 7925, Cape Town, South Africa
    AIDS 18:2096-8. 2004
    ..11% for p17p24, 0.32% for C2C3). In two individuals diversity was uncharacteristically lower in env C2C3 than in gag pl7p24, suggesting selection in env at this very early stage of infection...