Ashraf Coovadia

Summary

Country: South Africa

Publications

  1. ncbi request reprint Integration of antiretroviral treatment within antenatal care in Gauteng Province, South Africa
    Karin van der Merwe
    University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 43:577-81. 2006
  2. doi request reprint Reuse of nevirapine in exposed HIV-infected children after protease inhibitor-based viral suppression: a randomized controlled trial
    Ashraf Coovadia
    Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, Johannesburg, South Africa
    JAMA 304:1082-90. 2010
  3. doi request reprint HIV-1 drug resistance at antiretroviral treatment initiation in children previously exposed to single-dose nevirapine
    Gillian M Hunt
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    AIDS 25:1461-9. 2011
  4. pmc Lipid profiles in young HIV-infected children initiating and changing antiretroviral therapy
    Renate Strehlau
    Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 60:369-76. 2012
  5. pmc Absence seizures associated with efavirenz initiation
    Renate Strehlau
    Empilweni Services and Research Unit ESRU, Rahima Moosa Mother and Child Hospital, Johannesburg, South Africa
    Pediatr Infect Dis J 30:1001-3. 2011
  6. pmc Poor early virologic performance and durability of abacavir-based first-line regimens for HIV-infected children
    Karl Günter Technau
    Empilweni Services and Research Unit, Department of Paediatrics and Child Health, Rahima Moosa Mother and Child Hospital, Coronationville, Johannesburg, Gauteng, South Africa
    Pediatr Infect Dis J 32:851-5. 2013
  7. pmc Persistent minority K103N mutations among women exposed to single-dose nevirapine and virologic response to nonnucleoside reverse-transcriptase inhibitor-based therapy
    Ashraf Coovadia
    Empilweni Clinic, Coronation Women and Children Hospital, Johannesburg, South Africa
    Clin Infect Dis 48:462-72. 2009
  8. doi request reprint Paradoxical Mycobacterium tuberculosis Meningitis Immune Reconstitution Inflammatory Syndrome in an HIV-infected Child
    Emma Kalk
    From the Paediatric HIV Diagnostic Syndicate and Empilweni Services and Research Unit, Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Pediatr Infect Dis J 32:157-62. 2013
  9. pmc Effect of Maternal HIV-1 Status and Antiretroviral Drugs on Haematological Profiles of South African Infants in Early Life
    Diana B Schramm
    AIDS Virus Research Unit, National Institute for Communicable Diseases and Department of Virology, University of the Witwatersrand, Gauteng, South Africa
    Open AIDS J 4:156-65. 2010
  10. ncbi request reprint Vertical HIV transmission in South Africa: translating research into policy and practice
    Salim Abdool Karim
    University of Natal, 4041, South Africa
    Lancet 359:992-3. 2002

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Integration of antiretroviral treatment within antenatal care in Gauteng Province, South Africa
    Karin van der Merwe
    University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 43:577-81. 2006
    ..Further evaluation is needed of interventions linking antenatal with antiretroviral (ARV) treatment services and effectiveness of triple-ARV regimens for reducing MTCT in resource-constrained settings...
  2. doi request reprint Reuse of nevirapine in exposed HIV-infected children after protease inhibitor-based viral suppression: a randomized controlled trial
    Ashraf Coovadia
    Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, Johannesburg, South Africa
    JAMA 304:1082-90. 2010
    ..However, there are limitations of continuing PI-based therapy indefinitely and reuse of nevirapine has many advantages...
  3. doi request reprint HIV-1 drug resistance at antiretroviral treatment initiation in children previously exposed to single-dose nevirapine
    Gillian M Hunt
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    AIDS 25:1461-9. 2011
    ..To describe the prevalence of HIV-1 drug resistance mutations at the time of treatment initiation in a large cohort of HIV-infected children previously exposed to single-dose nevirapine (sdNVP) for prevention of transmission...
  4. pmc Lipid profiles in young HIV-infected children initiating and changing antiretroviral therapy
    Renate Strehlau
    Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 60:369-76. 2012
    ..Here we examined lipid profile changes in a cohort of young children before and after suppression on an initial ritonavir-boosted lopinavir (LPV/r)-based regimen and after switch to a nevirapine (NVP)-based regimen...
  5. pmc Absence seizures associated with efavirenz initiation
    Renate Strehlau
    Empilweni Services and Research Unit ESRU, Rahima Moosa Mother and Child Hospital, Johannesburg, South Africa
    Pediatr Infect Dis J 30:1001-3. 2011
    ..Plasma efavirenz values were above therapeutic range. The child was homozygous for the CYP2B6-516T/T genotype, which is associated with poor efavirenz clearance. Seizures abated after efavirenz discontinuation...
  6. pmc Poor early virologic performance and durability of abacavir-based first-line regimens for HIV-infected children
    Karl Günter Technau
    Empilweni Services and Research Unit, Department of Paediatrics and Child Health, Rahima Moosa Mother and Child Hospital, Coronationville, Johannesburg, Gauteng, South Africa
    Pediatr Infect Dis J 32:851-5. 2013
    ..Concerns about stavudine (d4T) toxicity have led to increased use of abacavir (ABC) in first-line pediatric antiretroviral treatment (ART) regimens. Field experience with ABC in ART-naïve children is limited...
  7. pmc Persistent minority K103N mutations among women exposed to single-dose nevirapine and virologic response to nonnucleoside reverse-transcriptase inhibitor-based therapy
    Ashraf Coovadia
    Empilweni Clinic, Coronation Women and Children Hospital, Johannesburg, South Africa
    Clin Infect Dis 48:462-72. 2009
    ....
  8. doi request reprint Paradoxical Mycobacterium tuberculosis Meningitis Immune Reconstitution Inflammatory Syndrome in an HIV-infected Child
    Emma Kalk
    From the Paediatric HIV Diagnostic Syndicate and Empilweni Services and Research Unit, Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Pediatr Infect Dis J 32:157-62. 2013
    ..We describe a fatal case of Mycobacterium tuberculosis meningitis immune reconstitution inflammatory syndrome in an HIV-infected child and review the literature...
  9. pmc Effect of Maternal HIV-1 Status and Antiretroviral Drugs on Haematological Profiles of South African Infants in Early Life
    Diana B Schramm
    AIDS Virus Research Unit, National Institute for Communicable Diseases and Department of Virology, University of the Witwatersrand, Gauteng, South Africa
    Open AIDS J 4:156-65. 2010
    ..These previously undescribed features may affect immune response capability in early life and clinical consequences of such changes need to be further investigated...
  10. ncbi request reprint Vertical HIV transmission in South Africa: translating research into policy and practice
    Salim Abdool Karim
    University of Natal, 4041, South Africa
    Lancet 359:992-3. 2002