Research Topics
| Salome CharalambousSummaryAffiliation: Aurum Institute for Health Research Country: South Africa Publications
| Collaborators
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Detail Information
Publications
Evaluation of a workplace HIV treatment programme in South AfricaSalome Charalambous
Aurum Institute for Health Research, Johannesburg, South Africa
AIDS 21:S73-8. 2007..To review the experience of implementing a workplace HIV care programme in South Africa and describe treatment outcomes in sequential cohorts of individuals starting antiretroviral therapy (ART)...- Contribution of reinfection to recurrent tuberculosis in South African gold minersS Charalambous
Aurum Institute for Health Research, Johannesburg, South Africa
Int J Tuberc Lung Dis 12:942-8. 2008..A gold mine in South Africa... 
Association of isoniazid preventive therapy with lower early mortality in individuals on antiretroviral therapy in a workplace programmeSalome Charalambous
The Aurum Institute, Johannesburg, South Africa
AIDS 24:S5-13. 2010..To describe the association between isoniazid preventive therapy (IPT) and mortality among individuals starting antiretroviral therapy (ART) in a workplace programme in South Africa where tuberculosis (TB) incidence is very high...- Establishing a workplace antiretroviral therapy programme in South AfricaS Charalambous
Aurum Institute for Health Research, Marshalltown, South Africa
AIDS Care 19:34-41. 2007..The model may be generalizable to other employment health services in settings of high HIV prevalence, and as a model for implementing ART in other types of health-care settings... 
Hepatitis B virus infection and response to antiretroviral therapy (ART) in a South African ART programChristopher J Hoffmann
Aurum Institute for Health Research and 2Toga Laboratories, Johannesburg, South Africa
Clin Infect Dis 47:1479-85. 2008..We evaluated the impact of chronic hepatitis B on HIV virologic response, changes in CD4 cell count, hepatotoxicity, and mortality among Africans receiving highly active antiretroviral therapy (HAART)...- Antiretroviral therapy using zidovudine, lamivudine, and efavirenz in South Africa: tolerability and clinical eventsChristopher J Hoffmann
Aurum Institute for Health Research, Johannesburg, South Africa
AIDS 22:67-74. 2008..To describe the safety and tolerability of zidovudine, lamivudine, and efavirenz in a low-income setting... - HIV suppression with stavudine 30 mg versus 40 mg in adults over 60 kg on antiretroviral therapy in South AfricaChristopher J Hoffmann
Aurum Institute for Health Research, Johannesburg, South Africa
AIDS 23:1784-6. 2009..6). In regression modeling, including baseline HIV RNA and nonnucleoside reverse transcriptase inhibitor agent, stavudine dose remained unassociated with suppression... - Reducing mortality with cotrimoxazole preventive therapy at initiation of antiretroviral therapy in South AfricaChristopher J Hoffmann
Aurum Institute, Johannesburg, South Africa
AIDS 24:1709-16. 2010..To assess the effectiveness of cotrimoxazole preventive therapy (CPT) among individuals with CD4 cell count above 200 cells/microl and varying WHO clinical stages in reducing mortality during combination antiretroviral therapy (cART)... - Hepatotoxicity in an African antiretroviral therapy cohort: the effect of tuberculosis and hepatitis BChristopher J Hoffmann
Aurum Institute for Health Research, Johannesburg, South Africa
AIDS 21:1301-8. 2007..Hepatotoxicity is a significant complication of antiretroviral therapy (ART). We assessed the incidence of and risk factors for hepatotoxicity among HIV-infected individuals on ART in South Africa... - A novel HIV treatment model using private practitioners in South AfricaCraig Innes
The Aurum Institute, Johannesburg, South Africa
Sex Transm Infect 88:136-40. 2012..The extent of the HIV epidemic in South Africa may render the public sector capacity inadequate to manage all patients requiring antiretroviral treatment (ART). Private practitioners are an underutilised resource... - Undiagnosed tuberculosis among HIV clinic attendees: association with antiretroviral therapy and implications for intensified case finding, isoniazid preventive therapy, and infection controlTendesayi Kufa
Aurum Institute for Health Research, Johannesburg, South Africa
J Acquir Immune Defic Syndr 60:e22-8. 2012..We describe factors associated with undiagnosed TB among HIV-infected patients attending an HIV clinic in South Africa and discuss implications for the 3 Is... - HIV infection does not affect active case finding of tuberculosis in South African gold minersJames J Lewis
Aurum Institute for Health Research, Postnet Suite 300, Private Bag X 30500, Houghton, Johannesburg, South Africa 2041
Am J Respir Crit Care Med 180:1271-8. 2009..Gold miners in South Africa undergo annual radiological screening for tuberculosis in an occupational health center of a gold mining company, but the optimal screening algorithm is unclear... - A study of patient attitudes towards decentralisation of HIV care in an urban clinic in South AfricaRachel Mukora
Aurum Institute, Johannesburg, South Africa
BMC Health Serv Res 11:205. 2011..This cross-sectional qualitative study investigates attitudes towards down-referral of ART delivery care among patients currently receiving care in a centralized tertiary HIV clinic... - Efficacy of secondary isoniazid preventive therapy among HIV-infected Southern Africans: time to change policy?Gavin J Churchyard
Aurum Health Research, Welkom, South Africa
AIDS 17:2063-70. 2003..To determine the efficacy of secondary preventive therapy against tuberculosis (TB) among gold miners working in South Africa... - Attitudes to directly observed antiretroviral treatment in a workplace HIV care programme in South AfricaLiesl S Page-Shipp
Aragon Consulting, Craighall, South Africa
Sex Transm Infect 83:383-6. 2007..To investigate attitudes to directly observed antiretroviral therapy (DOT ART) among HIV infected adults attending a workplace HIV care programme in South Africa... - Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa: a cohort studyKatherine L Fielding
London School of Hygiene and Tropical Medicine, London, UK
BMC Infect Dis 8:93. 2008..Reasons for the variation in reported treatment outcomes from antiretroviral therapy (ART) programmes in developing countries are not clearly defined... - "That is why I stopped the ART": patients' & providers' perspectives on barriers to and enablers of HIV treatment adherence in a South African workplace programmeMison Dahab
Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
BMC Public Health 8:63. 2008..This qualitative study examines potential barriers to, and facilitators of, adherence to ART in a workplace programme in South Africa... - Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-infected men in South Africa: a novel randomized incremental recruitment studyAlison D Grant
Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, England
JAMA 293:2719-25. 2005.... - Does tuberculosis increase HIV load?John H Day
London School of Hygiene and Tropical Medicine, London, United Kingdom
J Infect Dis 190:1677-84. 2004..The effect that tuberculosis (TB) has on human immunodeficiency virus (HIV) disease progression is not clearly understood... - Use of traditional medicine by HIV-infected individuals in South Africa in the era of antiretroviral therapyDale A Babb
Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
Psychol Health Med 12:314-20. 2007..Concomitant use with ART has the potential for drug interactions and should be discussed routinely in ART counselling. Further work is warranted to investigate whether commonly used traditional medicines interact with ART in vivo... - Human immunodeficiency virus and the prevalence of undiagnosed tuberculosis in African gold minersElizabeth L Corbett
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
Am J Respir Crit Care Med 170:673-9. 2004..The difference in mean duration of smear positivity was particularly marked and, if generalizable, will have major implications for TB control prospects in high HIV prevalence areas... - Stable incidence rates of tuberculosis (TB) among human immunodeficiency virus (HIV)-negative South African gold miners during a decade of epidemic HIV-associated TBElizabeth L Corbett
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
J Infect Dis 188:1156-63. 2003..94, for 1995-1997, 0.96, for 1998-1999, and 1.05, for 1999-2000. Preventing a secondary epidemic of TB among HIV-negative individuals may be achievable with conventional means, even in settings with a high burden of HIV-associated TB... - HIV infection and chronic chest disease as risk factors for bacterial pneumonia: a case-control studySalome Charalambous
Aurum Health Research, Welkom, South Africa
AIDS 17:1531-7. 2003..To investigate risk factors for severe acute pneumonia in South African gold miners...