Larry A Sonna

Summary

Publications

  1. ncbi request reprint Effect of moderate hypothermia on gene expression by THP-1 cells: a DNA microarray study
    Larry A Sonna
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA
    Physiol Genomics 26:91-8. 2006
  2. pmc A microarray analysis of the effects of moderate hypothermia and rewarming on gene expression by human hepatocytes (HepG2)
    Larry A Sonna
    Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cell Stress Chaperones 15:687-702. 2010
  3. ncbi request reprint Exertional heat illness and human gene expression
    Larry A Sonna
    Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Prog Brain Res 162:321-46. 2007
  4. ncbi request reprint Exertional heat injury and gene expression changes: a DNA microarray analysis study
    Larry A Sonna
    Thermal and Mountain Medicine Div, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Appl Physiol (1985) 96:1943-53. 2004
  5. ncbi request reprint Effect of acute heat shock on gene expression by human peripheral blood mononuclear cells
    Larry A Sonna
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol (1985) 92:2208-20. 2002
  6. ncbi request reprint Effect of hypoxia on gene expression by human hepatocytes (HepG2)
    Larry A Sonna
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Physiol Genomics 12:195-207. 2003
  7. doi request reprint Integrated physiological mechanisms of exercise performance, adaptation, and maladaptation to heat stress
    Michael N Sawka
    US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA
    Compr Physiol 1:1883-928. 2011
  8. ncbi request reprint Ontogeny of the eotaxins in human lung
    Kathleen J Haley
    Brigham and Women s Hospital, Division of Pulmonary and Critical Care Medicine, 75 Francis Street, Boston, MA 02115, USA
    Am J Physiol Lung Cell Mol Physiol 294:L214-24. 2008
  9. pmc Core temperature correlates with expression of selected stress and immunomodulatory genes in febrile patients with sepsis and noninfectious SIRS
    Larry A Sonna
    University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cell Stress Chaperones 15:55-66. 2010
  10. ncbi request reprint Invited review: Effects of heat and cold stress on mammalian gene expression
    Larry A Sonna
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol (1985) 92:1725-42. 2002

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Effect of moderate hypothermia on gene expression by THP-1 cells: a DNA microarray study
    Larry A Sonna
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA
    Physiol Genomics 26:91-8. 2006
    ..These in vitro findings suggest that prolonged hypothermia in vivo might be capable of producing physiologically relevant changes in gene expression by circulating leukocytes...
  2. pmc A microarray analysis of the effects of moderate hypothermia and rewarming on gene expression by human hepatocytes (HepG2)
    Larry A Sonna
    Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cell Stress Chaperones 15:687-702. 2010
    ..Thus, while some overlap occurs (particularly after rewarming), moderate hypothermia produces extensive, time-dependent gene expression changes in HepG2 cells that differ in important ways from those induced by heat shock...
  3. ncbi request reprint Exertional heat illness and human gene expression
    Larry A Sonna
    Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Prog Brain Res 162:321-46. 2007
    ....
  4. ncbi request reprint Exertional heat injury and gene expression changes: a DNA microarray analysis study
    Larry A Sonna
    Thermal and Mountain Medicine Div, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Appl Physiol (1985) 96:1943-53. 2004
    ..The molecular evidence from these patients is thus consistent with the hypothesis that EHI can result from cumulative effects of multiple adverse interacting stimuli...
  5. ncbi request reprint Effect of acute heat shock on gene expression by human peripheral blood mononuclear cells
    Larry A Sonna
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol (1985) 92:2208-20. 2002
    ..We conclude that heat shock causes extensive gene expression changes in PBMCs, affecting all functional categories of the heat shock response...
  6. ncbi request reprint Effect of hypoxia on gene expression by human hepatocytes (HepG2)
    Larry A Sonna
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Physiol Genomics 12:195-207. 2003
    ....
  7. doi request reprint Integrated physiological mechanisms of exercise performance, adaptation, and maladaptation to heat stress
    Michael N Sawka
    US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA
    Compr Physiol 1:1883-928. 2011
    ..Published 2011. This article is a U.S. Government work and is in the public domain in the USA...
  8. ncbi request reprint Ontogeny of the eotaxins in human lung
    Kathleen J Haley
    Brigham and Women s Hospital, Division of Pulmonary and Critical Care Medicine, 75 Francis Street, Boston, MA 02115, USA
    Am J Physiol Lung Cell Mol Physiol 294:L214-24. 2008
    ..We conclude that developing lung expresses the eotaxins and functional CCR3 receptor. CCL11 may promote airway epithelial proliferation in the developing lung...
  9. pmc Core temperature correlates with expression of selected stress and immunomodulatory genes in febrile patients with sepsis and noninfectious SIRS
    Larry A Sonna
    University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cell Stress Chaperones 15:55-66. 2010
    ..For some genes, it appears that clinical condition can alter temperature-sensitive gene expression. Collectively, these data underscore the potential importance of body temperature in shaping the immune response to infection and injury...
  10. ncbi request reprint Invited review: Effects of heat and cold stress on mammalian gene expression
    Larry A Sonna
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol (1985) 92:1725-42. 2002
    ..The similarities and differences between the cellular responses to heat and cold may yield key insights into how cells, and by extension tissues and organisms, survive and adapt to stress...
  11. ncbi request reprint Nitric oxide synthase-2 down-regulates surfactant protein-B expression and enhances endotoxin-induced lung injury in mice
    Rebecca M Baron
    Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    FASEB J 18:1276-8. 2004
    ..This study demonstrates that expression of NOS2 in lung epithelial cells is critical for the development of lung injury and mediates surfactant dysfunction independent of NOS2 inflammatory cell expression and cytokine production...
  12. ncbi request reprint DNA microarray analysis of vitamin D-induced gene expression in a human colon carcinoma cell line
    Richard J Wood
    Mineral Bioavailability Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston 02111, USA
    Physiol Genomics 17:122-9. 2004
    ..The known function of these genes suggests that many of them could be involved in the antiproliferative effects of 1,25-dihydroxyvitamin D3...
  13. ncbi request reprint Effects of allergen challenge on airway epithelial cell gene expression
    Craig M Lilly
    Pulmonary and Critical Care Division, Brigham and Women s Hospital, 75 Francis Street, Thorn 826C, Boston, MA 02115, USA
    Am J Respir Crit Care Med 171:579-86. 2005
    ....
  14. doi request reprint Heat shock protein 90beta: a novel mediator of vitamin D action
    Giana Angelo
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Mineral Bioavailability Laboratory, 711 Washington Street, Boston, MA 02111, USA
    Biochem Biophys Res Commun 367:578-83. 2008
    ..These findings indicate that Hsp90beta is needed for optimal vitamin D responsiveness in the enterocyte and demonstrate a specific role for Hsp90beta in VDR signaling...