Song Y, Shi Y, Ao L, Harken A, Meng X. TLR4 mediates LPS-induced HO-1 expression in mouse liver: role of TNF-alpha and IL-1beta. World J Gastroenterol. 2003;9:1799-803 pubmed
..This study demonstrates that TLR4 plays a dominant role in mediating HO-1 expression following LPS. LPS-induced HO-1 expression is mainly mediated by endogenous TNF-alpha, but only partially by endogenous IL-1beta. ..
Ma C, Shi X, Zhu Q, Li Q, Liu Y, Yao Y, et al
. The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers. Tumour Biol. 2016;37:1437-44 pubmed publisher
..In this review, we will summarize the current knowledge about this vital lncRNA, from its discovery, characteristics, and biological function to molecular mechanism in various neoplasms. ..
Zhan P, Zhang B, Xi G, Wu Y, Liu H, Liu Y, et al
. PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway. Mol Cancer. 2017;16:108 pubmed publisher
Zhang Q, Liu H, Zhu Q, Zhan P, Zhu S, Zhang J, et al
. Patterns and functional implications of platelets upon tumor "education". Int J Biochem Cell Biol. 2017;90:68-80 pubmed publisher
..Further studies with well-designed prospective multicenter trials may contribute to clinical "liquid biopsy" diagnosis by evaluating the global changes of platelets. ..
Zhou L, Lv T, Zhang Q, Zhu Q, Zhan P, Zhu S, et al
. The biology, function and clinical implications of exosomes in lung cancer. Cancer Lett. 2017;407:84-92 pubmed publisher
..In addition, we also discuss current challenges that might impede the clinical use of exosomes. Further studies on the functional roles of exosomes in lung cancer requires thorough research. ..
Gao J, Qiu X, Li X, Fan H, Zhang F, Lv T, et al
. Expression profiles and clinical value of plasma exosomal Tim-3 and Galectin-9 in non-small cell lung cancer. Biochem Biophys Res Commun. 2018;498:409-415 pubmed publisher
..Together, our data revealed that Exo-pro, especially Exo-T and Exo-G could be potential biomarkers for NSCLC. Further studies focusing on pure tumor-derived exosomes isolated from plasma were needed. ..
Miao L, Wang Y, Zhu S, Shi M, Li Y, Ding J, et al
. Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients. BMC Cancer. 2014;14:369 pubmed publisher
Zhang F, Su X, Huang G, Xin X, Cao E, Shi Y, et al
. sRAGE alleviates neutrophilic asthma by blocking HMGB1/RAGE signalling in airway dendritic cells. Sci Rep. 2017;7:14268 pubmed publisher
..Thus, sRAGE prevents Th17-mediated airway inflammation in neutrophilic asthma at least partly by blocking HMGB1/RAGE signalling in DCs. ..