Song Y, Shi Y, Ao L, Harken A, Meng X. TLR4 mediates LPS-induced HO-1 expression in mouse liver: role of TNF-alpha and IL-1beta. World J Gastroenterol. 2003;9:1799-803 pubmed
..This study demonstrates that TLR4 plays a dominant role in mediating HO-1 expression following LPS. LPS-induced HO-1 expression is mainly mediated by endogenous TNF-alpha, but only partially by endogenous IL-1beta. ..
Wu L, Xu W, Wang F, Lv T, Yin Z, Song Y. Plasma mtDNA Analysis Aids in Predicting Pancreatic Necrosis in Acute Pancreatitis Patients: A Pilot Study. Dig Dis Sci. 2018;63:2975-2982 pubmed publisher
..7 [IQR 307.00-1370.00] vs. 237.5 [IQR 117.20-464.80] pg/ml, P < 0.01). Elevated plasma mtDNA content in AP patients may be used as a more accurate early predictor of PNec in contrast to traditional CRP. ..
Song Y, Zhou Q, Zhang X, Chen G, Zhong D, Yu Z, et al
. Factors associated with gene aberration test status and treatment decision in patients with unresectable Stage IIIB/IV nonsquamous non-small cell lung cancer: A multicenter survey in China (CTONG 1506). Lung Cancer. 2018;123:7-13 pubmed publisher
Wan B, Xu W, Zhan P, Jin J, Xi G, Chen M, et al
. Topotecan alleviates ventilator-induced lung injury via NF-?B pathway inhibition. Cytokine. 2018;110:381-388 pubmed publisher
..Moreover, topotecan inhibited NF-?B expression and activation in the VILI model. Topotecan alleviates acute lung injury in the model of VILI through the inhibition of the NF-?B pathway. ..
Zhang Q, Hu H, Liu H, Jin J, Zhu P, Wang S, et al
. RNA sequencing enables systematic identification of platelet transcriptomic alterations in NSCLC patients. Biomed Pharmacother. 2018;105:204-214 pubmed publisher
..The outcomes from subgroup analysis between lung adenocarcinoma and lung squamous cell carcinoma demonstrated the diagnostic potential of platelet RNA-Seq on distinguishing tumor histological types. ..
Gu X, Wu G, Yao Y, Zeng J, Shi D, Lv T, et al
. Intratracheal administration of mitochondrial DNA directly provokes lung inflammation through the TLR9-p38 MAPK pathway. Free Radic Biol Med. 2015;83:149-58 pubmed publisher
Zhang F, Huang G, Hu B, Qian G, Song Y. Recombinant HMGB1 A box protein inhibits Th17 responses in mice with neutrophilic asthma by suppressing dendritic cell-mediated Th17 polarization. Int Immunopharmacol. 2015;24:110-8 pubmed publisher
..These data demonstrate that rHMGB1 A box may have therapeutic effects on controlling Th17 polarization and airway inflammation in neutrophilic asthma by blocking the HMGB1 pathway on DCs. ..
Liu H, Wu Y, Zhu S, Liang W, Wang Z, Wang Y, et al
. PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer. Cancer Lett. 2015;359:218-25 pubmed publisher
..Our study uncovered that PTP1B can promote NSCLC proliferation and metastasis by activating src and subsequently ERK1/2 and provides a theoretical basis for future applications of PTP1B inhibitors in the treatment of NSCLC. ..
Yuan D, Zhang Q, Lv Y, Ma X, Zhang Y, Liu H, et al
. Predictive and prognostic significance of circulating endothelial cells in advanced non-small cell lung cancer patients. Tumour Biol. 2015;36:9031-7 pubmed publisher
..And the reduction of CECs after treatment might be more ideal than the baseline CEC counts as a predictive or prognostic factor in patients treated with chemotherapy or anti-angiogenic therapy. ..