Kyoung Sub Song

Summary

Publications

  1. pmc Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells
    Soyeon Jeong
    Department of Biochemistry, School of Medicine, Chungnam National University, Daejeon 301 747, Korea
    BMC Cancer 14:481. 2014
  2. pmc Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/β-catenin in SW480 human colon cancer cells
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Joong Gu, Daejeon, Korea
    BMC Cancer 11:307. 2011
  3. doi request reprint Apicularen A acetate induces cell death via AIF translocation and disrupts the microtubule network by down-regulating tubulin in HM7 human colon cancer cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
    Biochem Biophys Res Commun 434:634-40. 2013
  4. pmc The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53
    Soyeon Shin
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon 301 747, Republic of Korea
    Biomed Res Int 2013:568671. 2013
  5. doi request reprint Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Pancreatology 11:574-84. 2011
  6. ncbi request reprint Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis
    Kyoung Sub Song
    Department of Biochemistry, Chungnam National University, Munhwa dong, Joong Gu, Daejeon, Korea
    Autophagy 4:650-8. 2008
  7. doi request reprint Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells
    Jun Young Heo
    Department of Biochemistry, College of Medicine, Chungnam National University, Teajeon, South Korea
    Stem Cells 27:1455-62. 2009
  8. pmc PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    BMC Cancer 14:36. 2014
  9. ncbi request reprint Phosphorylation of octamer-binding transcriptional factor may be correlated with H2B histone gene repression during 12-O-tetradecanoylphorbol 13-acetate-dependent differentiation of HL-60 cells
    Kyu Lim
    Department of Biochemistry, College of Medicine, Chungnam National University, Jungu, Daejeon 301 747, Korea
    Oncol Rep 14:727-31. 2005
  10. pmc Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer
    Tae Dong Kim
    Department of Surgery, College of Medicine, Chungnam National University and Hospital, Daejeon, 301 721, Korea
    BMC Cancer 6:211. 2006

Collaborators

Detail Information

Publications15

  1. pmc Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells
    Soyeon Jeong
    Department of Biochemistry, School of Medicine, Chungnam National University, Daejeon 301 747, Korea
    BMC Cancer 14:481. 2014
    ....
  2. pmc Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/β-catenin in SW480 human colon cancer cells
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Joong Gu, Daejeon, Korea
    BMC Cancer 11:307. 2011
    ..However, the molecular mechanisms responsible for the anti-tumor properties of PL remain to be explored. Experiments were carried out to unravel the anticancer effects of PL...
  3. doi request reprint Apicularen A acetate induces cell death via AIF translocation and disrupts the microtubule network by down-regulating tubulin in HM7 human colon cancer cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
    Biochem Biophys Res Commun 434:634-40. 2013
    ..Taken together, these results indicate that the mechanism of apicularen A acetate involves caspase-independent apoptotic cell death and disruption of microtubule architecture...
  4. pmc The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53
    Soyeon Shin
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon 301 747, Republic of Korea
    Biomed Res Int 2013:568671. 2013
    ..Collectively, these findings present a novel mechanism of ROS-regulated apoptosis and autophagy that involves Akt-mTOR signaling in prostate cancer cells with mutant p53 exposed to DHA. ..
  5. doi request reprint Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Pancreatology 11:574-84. 2011
    ..However, the relationship between ω3-PUFAs and β-catenin, one of the key components of the Wnt signaling pathway, in human pancreatic cancer remains poorly characterized...
  6. ncbi request reprint Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis
    Kyoung Sub Song
    Department of Biochemistry, Chungnam National University, Munhwa dong, Joong Gu, Daejeon, Korea
    Autophagy 4:650-8. 2008
    ....
  7. doi request reprint Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells
    Jun Young Heo
    Department of Biochemistry, College of Medicine, Chungnam National University, Teajeon, South Korea
    Stem Cells 27:1455-62. 2009
    ..Maintaining characteristics of hBMSCs by regulating intracellular reactive oxygen species production can contribute to tissue regeneration and to improved cell therapy...
  8. pmc PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    BMC Cancer 14:36. 2014
    ..Apicularen A induces cytotoxicity in tumor cells through disrupting microtubule networks by tubulin down-regulation. In this study, we examined whether PMA increases apicularen A-induced cytotoxicity in HeLa cells...
  9. ncbi request reprint Phosphorylation of octamer-binding transcriptional factor may be correlated with H2B histone gene repression during 12-O-tetradecanoylphorbol 13-acetate-dependent differentiation of HL-60 cells
    Kyu Lim
    Department of Biochemistry, College of Medicine, Chungnam National University, Jungu, Daejeon 301 747, Korea
    Oncol Rep 14:727-31. 2005
    ....
  10. pmc Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer
    Tae Dong Kim
    Department of Surgery, College of Medicine, Chungnam National University and Hospital, Daejeon, 301 721, Korea
    BMC Cancer 6:211. 2006
    ..We designed this study to determine any differences in the expression of MMP-2, MMP-9 and uPA system between colon and rectal cancer tissues...
  11. ncbi request reprint Apicularen A induces cell death through Fas ligand up-regulation and microtubule disruption by tubulin down-regulation in HM7 human colon cancer cells
    Jong Seok Kim
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
    Clin Cancer Res 13:6509-17. 2007
    ..In this study, we investigated the molecular mechanisms of apicularen A-induced cell death in HM7 human colon cancer cells in vitro and anticancer activity in vivo...
  12. ncbi request reprint Bacillus calmette-guerin cell wall cytoskeleton enhances colon cancer radiosensitivity through autophagy
    Jae Min Yuk
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, Korea
    Autophagy 6:46-60. 2010
    ..Our data suggest that BCG/CWS in combination with IR is a promising therapeutic strategy for enhancing radiation therapy in colon cancer cells through the induction of autophagy...
  13. doi request reprint Radiation-induced thymidine phosphorylase upregulation in rectal cancer is mediated by tumor-associated macrophages by monocyte chemoattractant protein-1 from cancer cells
    Tae Dong Kim
    Department of Biochemistry, Chungnam National University College of Medicine, Daejon, Korea
    Int J Radiat Oncol Biol Phys 73:853-60. 2009
    ..The mechanisms of thymidine phosphorylase (TP) regulation induced by radiation therapy (XRT) in various tumors are poorly understood. We investigated the effect and mechanisms of preoperative XRT on TP expression in rectal cancer tissues...
  14. pmc Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53
    Kaipeng Jing
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Autophagy 7:1348-58. 2011
    ..Overall, our results demonstrate that autophagy contributes to the cytotoxicity of DHA in cancer cells harboring wild-type p53...
  15. doi request reprint Expression regulation and function of Pref-1 during adipogenesis of human mesenchymal stem cells (MSCs)
    Kaipeng Jing
    Department of Biochemistry, Medical School of Chungnam National University, Daejeon, Republic of Korea
    Biochim Biophys Acta 1791:816-26. 2009
    ..Taken together, our study demonstrates that IBMX accelerates accumulation of lipid in MSCs only under the circumstance that the negative effect of Pref-1 induced by IBMX on the adipogenesis is overcome by dexamethasone...