Soja Saghar Soman

Summary

Publications

  1. pmc Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2
    Soja Saghar Soman
    Molecular Virology Laboratory, Department of Molecular Microbiology, Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Thiruvananthapuram 695014, Kerala, India
    BMC Bioinformatics 11:S7. 2010
  2. doi request reprint Discovery of Anas platyrhynchos avian beta-defensin 2 (Apl_AvBD2) with antibacterial and chemotactic functions
    Soja Saghar Soman
    Molecular Immunology and Virology Laboratory, Department of Molecular Microbiology, Rajiv Gandhi Centre for Biotechnology RGCB, Thycaud PO, Trivandrum 695014, Kerala, India
    Mol Immunol 46:2029-38. 2009
  3. doi request reprint Functional characterization of the CC chemokine RANTES from Pekin duck (Anas platyrhynchos)
    D S Arathy
    Molecular Virology Laboratory, Rajiv Gandhi Centre for Biotechnology RGCB, Thycaud P O, Thiruvananthapuram 695014, Kerala, India
    Dev Comp Immunol 35:142-50. 2011
  4. doi request reprint Immunomodulation by duck defensin, Apl_AvBD2: in vitro dendritic cell immunoreceptor (DCIR) mRNA suppression, and B- and T-lymphocyte chemotaxis
    Soja Saghar Soman
    Molecular Virology Laboratory, Department of Molecular Microbiology, Rajiv Gandhi Centre for Biotechnology RGCB, Thycaud PO, Thiruvananthapuram 695014, Kerala, India
    Mol Immunol 46:3070-5. 2009

Collaborators

Detail Information

Publications4

  1. pmc Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2
    Soja Saghar Soman
    Molecular Virology Laboratory, Department of Molecular Microbiology, Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Thiruvananthapuram 695014, Kerala, India
    BMC Bioinformatics 11:S7. 2010
    ..Mutant proteins were made by in vitro site directed mutagenesis and recombinant protein expression, and tested for antimicrobial activity to confirm the results obtained in MD simulation analysis...
  2. doi request reprint Discovery of Anas platyrhynchos avian beta-defensin 2 (Apl_AvBD2) with antibacterial and chemotactic functions
    Soja Saghar Soman
    Molecular Immunology and Virology Laboratory, Department of Molecular Microbiology, Rajiv Gandhi Centre for Biotechnology RGCB, Thycaud PO, Trivandrum 695014, Kerala, India
    Mol Immunol 46:2029-38. 2009
    ..It may play a vital role in the immune response of these birds against bacterial and viral pathogens...
  3. doi request reprint Functional characterization of the CC chemokine RANTES from Pekin duck (Anas platyrhynchos)
    D S Arathy
    Molecular Virology Laboratory, Rajiv Gandhi Centre for Biotechnology RGCB, Thycaud P O, Thiruvananthapuram 695014, Kerala, India
    Dev Comp Immunol 35:142-50. 2011
    ..Our results show that the duck RANTES has overlapping biological properties with its mammalian orthologue, and also has possible functional cross-reactivity with chicken immune cells indicated by the chemotaxis of DT-40 cells...
  4. doi request reprint Immunomodulation by duck defensin, Apl_AvBD2: in vitro dendritic cell immunoreceptor (DCIR) mRNA suppression, and B- and T-lymphocyte chemotaxis
    Soja Saghar Soman
    Molecular Virology Laboratory, Department of Molecular Microbiology, Rajiv Gandhi Centre for Biotechnology RGCB, Thycaud PO, Thiruvananthapuram 695014, Kerala, India
    Mol Immunol 46:3070-5. 2009
    ..Our results reveal chemotactic and immunomodulatory properties of Apl_AvBD2, two important functions that would help in employing this protein as a molecular adjuvant with avian vaccines...