Cristina Solomon

Summary

Publications

  1. pmc Effect of haematocrit on fibrin-based clot firmness in the FIBTEM test
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care, Salzburger Landeskliniken SALK, Salzburg, Austria
    Blood Transfus 11:412-8. 2013
  2. pmc Time course of haemostatic effects of fibrinogen concentrate administration in aortic surgery
    C Solomon
    Department of Anaesthesiology and Intensive Care Medicine, SALK University Hospital, Salzburg, Austria
    Br J Anaesth 110:947-56. 2013
  3. pmc Haemostatic monitoring during postpartum haemorrhage and implications for management
    C Solomon
    Department of Anaesthesiology and Intensive Care, Salzburger Landeskliniken SALK, 48 Müllner Hauptstrasse, 5020 Salzburg, Austria
    Br J Anaesth 109:851-63. 2012
  4. pmc Early and individualized goal-directed therapy for trauma-induced coagulopathy
    Herbert Schöchl
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Vienna, Austria
    Scand J Trauma Resusc Emerg Med 20:15. 2012
  5. pmc FIBTEM provides early prediction of massive transfusion in trauma
    Herbert Schöchl
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and AUVA Research Centre, Donaueschingenstraße 13, A 1200 Vienna, Austria
    Crit Care 15:R265. 2011
  6. doi request reprint Comparison of whole blood fibrin-based clot tests in thrombelastography and thromboelastometry
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care, Salzburger Landeskliniken SALK, 48 Müllner Hauptstrasse, 5020 Salzburg, Austria
    Anesth Analg 114:721-30. 2012
  7. doi request reprint Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: comparison of fibrinogen concentrate with allogeneic blood products
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care Medicine, SALK University Hospital, Salzburg, Austria
    Scand J Clin Lab Invest 72:121-8. 2012
  8. pmc Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy
    Herbert Schöchl
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Donaueschingenstrasse 13, A 1200 Vienna, Austria
    Crit Care 15:R83. 2011
  9. doi request reprint Platelet concentrates transfusion in cardiac surgery in relation to preoperative point-of-care assessment of platelet adhesion and aggregation
    Cristina Solomon
    Department of Anaesthesiology und Intensive Care, Hannover Medical School, Hannover, Germany
    Platelets 21:221-8. 2010
  10. pmc Recovery of fibrinogen after administration of fibrinogen concentrate to patients with severe bleeding after cardiopulmonary bypass surgery
    C Solomon
    Department of Anaesthesiology and Intensive Care, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Br J Anaesth 104:555-62. 2010

Detail Information

Publications28

  1. pmc Effect of haematocrit on fibrin-based clot firmness in the FIBTEM test
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care, Salzburger Landeskliniken SALK, Salzburg, Austria
    Blood Transfus 11:412-8. 2013
    ..We investigated the relationships between FIBTEM maximum clot firmness (MCF), whole blood fibrinogen concentration and plasma fibrinogen concentration to determine the impact of haematocrit on these parameters during cardiac surgery...
  2. pmc Time course of haemostatic effects of fibrinogen concentrate administration in aortic surgery
    C Solomon
    Department of Anaesthesiology and Intensive Care Medicine, SALK University Hospital, Salzburg, Austria
    Br J Anaesth 110:947-56. 2013
    ..This analysis evaluates the effects of fibrinogen concentrate on coagulation up to 12 days after administration during aortic surgery...
  3. pmc Haemostatic monitoring during postpartum haemorrhage and implications for management
    C Solomon
    Department of Anaesthesiology and Intensive Care, Salzburger Landeskliniken SALK, 48 Müllner Hauptstrasse, 5020 Salzburg, Austria
    Br J Anaesth 109:851-63. 2012
    ..Improving awareness of the correct application and interpretation of viscoelastic coagulation monitoring techniques may be critical in realizing their emergency diagnostic potential...
  4. pmc Early and individualized goal-directed therapy for trauma-induced coagulopathy
    Herbert Schöchl
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Vienna, Austria
    Scand J Trauma Resusc Emerg Med 20:15. 2012
    ..The concept of early, individualized and goal-directed therapy is explored in this review and the AUVA Trauma Hospital algorithm for managing trauma-induced coagulopathy is presented...
  5. pmc FIBTEM provides early prediction of massive transfusion in trauma
    Herbert Schöchl
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and AUVA Research Centre, Donaueschingenstraße 13, A 1200 Vienna, Austria
    Crit Care 15:R265. 2011
    ..Whole-blood thromboelastometry (ROTEM®) tests provide immediate information about the coagulation status of acute bleeding trauma patients. We investigated their value for early prediction of MT...
  6. doi request reprint Comparison of whole blood fibrin-based clot tests in thrombelastography and thromboelastometry
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care, Salzburger Landeskliniken SALK, 48 Müllner Hauptstrasse, 5020 Salzburg, Austria
    Anesth Analg 114:721-30. 2012
    ..Our objective was to compare clot firmness parameters through standard (FF on a thrombelastography device [TEG®]; FIBTEM on a thromboelastometry device [ROTEM®]) and crossover (FF on ROTEM®; FIBTEM on TEG®) analyses...
  7. doi request reprint Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: comparison of fibrinogen concentrate with allogeneic blood products
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care Medicine, SALK University Hospital, Salzburg, Austria
    Scand J Clin Lab Invest 72:121-8. 2012
    ..We compared patient outcomes following fibrinogen concentrate administration or transfusion of allogeneics in CABG patients with decreased platelet function...
  8. pmc Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy
    Herbert Schöchl
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Donaueschingenstrasse 13, A 1200 Vienna, Austria
    Crit Care 15:R83. 2011
    ....
  9. doi request reprint Platelet concentrates transfusion in cardiac surgery in relation to preoperative point-of-care assessment of platelet adhesion and aggregation
    Cristina Solomon
    Department of Anaesthesiology und Intensive Care, Hannover Medical School, Hannover, Germany
    Platelets 21:221-8. 2010
    ..47 and -0.62, p < 0.05). Multiple electrode aggregometry appeared more useful and easier to apply than CPA for preoperatively identifying patients with platelet concentrates transfusion in cardiac surgery...
  10. pmc Recovery of fibrinogen after administration of fibrinogen concentrate to patients with severe bleeding after cardiopulmonary bypass surgery
    C Solomon
    Department of Anaesthesiology and Intensive Care, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Br J Anaesth 104:555-62. 2010
    ..Data on transfusion and patient outcomes were also collected...
  11. doi request reprint Acquired type 2A von Willebrand syndrome caused by aortic valve disease corrects during valve surgery
    C Solomon
    Department of Anaesthesiology and Intensive Care, Salzburger Landeskliniken SALK, Salzburg, Austria
    Br J Anaesth 106:494-500. 2011
    ..We hypothesized that the preoperative VWF HMWM defect corrects already during cardiopulmonary bypass (CPB) before any haemostatic therapy...
  12. doi request reprint A comparison of fibrinogen measurement methods with fibrin clot elasticity assessed by thromboelastometry, before and after administration of fibrinogen concentrate in cardiac surgery patients
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care and the Institute of Medical and Chemical Laboratory Diagnostics, Salzburger Landeskliniken SALK, Salzburg, Austria
    Transfusion 51:1695-706. 2011
    ....
  13. doi request reprint Fibrin formation is more impaired than thrombin generation and platelets immediately following cardiac surgery
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care, Salzburger Landeskliniken SALK, Salzburg, Austria
    Thromb Res 128:277-82. 2011
    ..The effects of haemostatic therapy with fresh frozen plasma (FFP) and platelet concentrate on these parameters were also evaluated...
  14. doi request reprint The effectiveness of different functional fibrinogen polymerization assays in eliminating platelet contribution to clot strength in thromboelastometry
    Christoph J Schlimp
    From the Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and AUVA Research Centre, Vienna Department of Anesthesiology and Intensive Care, Salzburger Landeskliniken SALK, Salzburg, Austria CSL Behring, Marburg, Germany Department of Cardiothoracic and Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, Milan, Italy and Department of Anesthesiology and Intensive Care, AUVA Trauma Hospital of Salzburg, Salzburg, Austria
    Anesth Analg 118:269-76. 2014
    ..Incomplete platelet inhibition influences maximum clot firmness (MCF) of FFPAs. We compared the ability of existing and newly developed FFPAs to eliminate the platelet contribution to clot strength...
  15. doi request reprint FIBTEM PLUS provides an improved thromboelastometry test for measurement of fibrin-based clot quality in cardiac surgery patients
    Cristina Solomon
    From the Department of Anesthesiology and Intensive Care, Salzburger Landeskliniken SALK, Salzburg, Austria CSL Behring, Marburg, Germany Department of Cardiothoracic and Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, Milan, Italy Haemostasis Research, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and AUVA Research Centre, Vienna, Austria Department of Anesthesiology and Intensive Care, AUVA Trauma Hospital of Salzburg, Salzburg, Austria and Laboratory Medicine, Unilabs Coagulation Laboratory, Zurich, Switzerland
    Anesth Analg 117:1054-62. 2013
    ..Inhibition of platelet function is a necessary precondition for these tests to work. We investigated a novel test for measuring fibrin-based clotting, FIBTEM PLUS, in cardiac surgery and compared it with FF and FIBTEM...
  16. doi request reprint Platelet function following trauma. A multiple electrode aggregometry study
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care Medicine, AUVA Trauma Centre, Salzburg, Austria
    Thromb Haemost 106:322-30. 2011
    ..Further studies are warranted to confirm these results and investigate the role of platelet function in trauma haemostatic management...
  17. doi request reprint Comparative assessment of coagulation changes induced by two different types of heart-lung machine
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    Artif Organs 34:3-12. 2010
    ..01, ProcMixed test). Our findings suggest that MEA and thromboelastometry reflect impairment of coagulation in cardiac surgery performed on different types of HLM and that platelet function is less affected by MECC than by standard HLM...
  18. doi request reprint The effects of fibrinogen levels on thromboelastometric variables in the presence of thrombocytopenia
    Thomas Lang
    Department of Anesthesiology, Medical School, Hannover, Germany
    Anesth Analg 108:751-8. 2009
    ..In this study, we investigated the effect of fibrinogen concentration and its relative contribution to overall clot strength using ROTEM...
  19. doi request reprint An evaluation of cyclooxygenase-1 inhibition before coronary artery surgery: aggregometry versus patient self-reporting
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Anesth Analg 107:1791-7. 2008
    ..Our objective was to compare the assessment of aspirin intake by patient self-reporting and by measurement of platelet function with regard to transfusion requirements...
  20. doi request reprint Thromboelastometry-guided administration of fibrinogen concentrate for the treatment of excessive intraoperative bleeding in thoracoabdominal aortic aneurysm surgery
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    J Thorac Cardiovasc Surg 138:694-702. 2009
    ..We assessed the efficacy of intraoperative post-cardiopulmonary bypass administration of fibrinogen concentrate in elective thoracoabdominal aortic aneurysm surgery...
  21. pmc Bleeding management with fibrinogen concentrate targeting a high-normal plasma fibrinogen level: a pilot study
    N Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Carl Neuberg Str 1, Hannover D 30625, Germany
    Br J Anaesth 102:785-92. 2009
    ..The aim was to compare haemostatic effects of conventional transfusion management and FIBTEM (thromboelastometry test)-guided fibrinogen concentrate administration...
  22. pmc Influence of the sample anticoagulant on the measurements of impedance aggregometry in cardiac surgery
    Cristina Solomon
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    Med Devices (Auckl) 1:23-30. 2008
    ....
  23. pmc Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate
    Herbert Schöchl
    Department of Anaesthesiology and Intensive Care, AUVA Trauma Hospital, Dr Franz Rehrl Platz 5, Salzburg, Austria
    Crit Care 14:R55. 2010
    ..The appropriate strategy for trauma-induced coagulopathy management is under debate. We report the treatment of major trauma using mainly coagulation factor concentrates...
  24. doi request reprint Multicentric comparison of single portion reagents and liquid reagents for thromboelastometry
    Niels Rahe-Meyer
    Department of Anesthesia, Hannover Medical School, 30625 Hannover, Germany
    Blood Coagul Fibrinolysis 20:218-22. 2009
    ..85-0.99). The SPR reagents showed excellent stability against thermic stress and the measurements were easier to perform than with the conventional liquid reagents system...
  25. doi request reprint Severe pediatric blunt trauma--successful ROTEM-guided hemostatic therapy with fibrinogen concentrate and no administration of fresh frozen plasma or platelets
    Bernhard Ziegler
    Department of Anaesthesiology, Perioperative Medicine and General Intensive Care, SALK University Hospital, Salzburg, Austria
    Clin Appl Thromb Hemost 19:453-9. 2013
    ..This case shows the potential for hemostatic treatment with coagulation factor concentrates to be applied to pediatric trauma. ..
  26. doi request reprint Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate
    H Schöchl
    Department of Anaesthesiology and Critical Care Medicine, AUVA Trauma Centre, Salzburg, Austria
    Anaesthesia 65:199-203. 2010
    ..This case shows the potential success of treatment using both fibrinogen concentrate and prothrombin complex concentrate, not only in restoring haemostasis but also in minimising requirement for transfusion of allogeneic blood products...
  27. doi request reprint Similarities in thromboelastometric (ROTEM®) findings between humans and baboons
    Herbert Schöchl
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Vienna, Austria
    Thromb Res 130:e107-12. 2012
    ..Interest in visco-elastic testing in different clinical scenarios has increased but few data are available on thromboelastometric findings in primates...
  28. doi request reprint Platelet concentrates transfusion in cardiac surgery and platelet function assessment by multiple electrode aggregometry
    N Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Hannover, Germany
    Acta Anaesthesiol Scand 53:168-75. 2009
    ..We evaluated the usefulness of the Multiplate platelet function analyser based on impedance aggregometry for identifying groups of patients at a high risk of transfusion of platelet concentrates (PC)...