Timothy D Solberg

Summary

Publications

  1. doi request reprint Stereotactic body radiation therapy: a new paradigm in radiotherapy management of cancer
    Timothy D Solberg
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Am Coll Radiol 5:673-7. 2008
  2. pmc Quantifying the interplay effect in prostate IMRT delivery using a convolution-based method
    Haisen S Li
    Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, Nebraska 68198 7521, USA
    Med Phys 35:1703-10. 2008
  3. doi request reprint Quality assurance of immobilization and target localization systems for frameless stereotactic cranial and extracranial hypofractionated radiotherapy
    Timothy D Solberg
    Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198 7521, USA
    Int J Radiat Oncol Biol Phys 71:S131-5. 2008
  4. pmc Spinal cord tolerance to reirradiation with single-fraction radiosurgery: a swine model
    Paul M Medin
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Int J Radiat Oncol Biol Phys 83:1031-7. 2012
  5. ncbi request reprint Segmental and dynamic intensity-modulated radiotherapy delivery techniques for micro-multileaf collimator
    Nzhde Agazaryan
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 6951, USA
    Med Phys 30:1758-67. 2003
  6. pmc Spinal cord tolerance to single-session uniform irradiation in pigs: implications for a dose-volume effect
    Paul M Medin
    Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390 8542, USA
    Radiother Oncol 106:101-5. 2013
  7. doi request reprint Use of the BrainLAB ExacTrac X-Ray 6D system in image-guided radiotherapy
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Med Dosim 33:124-34. 2008
  8. ncbi request reprint Optimization of multi-slice helical respiration-correlated CT: the effects of table speed and rotation time
    Nicole M Wink
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Phys Med Biol 50:5717-29. 2005
  9. ncbi request reprint Targeting accuracy of an image guided gating system for stereotactic body radiotherapy
    Stephen E Tenn
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Phys Med Biol 50:5443-62. 2005
  10. ncbi request reprint A methodology for verification of radiotherapy dose calculation
    Nzhde Agazaryan
    Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California 90095 6951, USA
    J Neurosurg 101:356-61. 2004

Detail Information

Publications49

  1. doi request reprint Stereotactic body radiation therapy: a new paradigm in radiotherapy management of cancer
    Timothy D Solberg
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Am Coll Radiol 5:673-7. 2008
  2. pmc Quantifying the interplay effect in prostate IMRT delivery using a convolution-based method
    Haisen S Li
    Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, Nebraska 68198 7521, USA
    Med Phys 35:1703-10. 2008
    ..3%, in single fraction plans. For entire treatment courses delivered in either a hypofractionated (five fractions) or conventional (> 30 fractions) regimen, the discrepancy in total dose due to interplay effect was negligible...
  3. doi request reprint Quality assurance of immobilization and target localization systems for frameless stereotactic cranial and extracranial hypofractionated radiotherapy
    Timothy D Solberg
    Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198 7521, USA
    Int J Radiat Oncol Biol Phys 71:S131-5. 2008
    ..In this report, we reviewed the technologies for frameless localization of cranial and extracranial targets with emphasis on the quality assurance aspects...
  4. pmc Spinal cord tolerance to reirradiation with single-fraction radiosurgery: a swine model
    Paul M Medin
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Int J Radiat Oncol Biol Phys 83:1031-7. 2012
    ..This study was performed to determine swine spinal cord tolerance to single-fraction, partial-volume irradiation 1 year after receiving uniform irradiation to 30 Gy in 10 fractions...
  5. ncbi request reprint Segmental and dynamic intensity-modulated radiotherapy delivery techniques for micro-multileaf collimator
    Nzhde Agazaryan
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 6951, USA
    Med Phys 30:1758-67. 2003
    ....
  6. pmc Spinal cord tolerance to single-session uniform irradiation in pigs: implications for a dose-volume effect
    Paul M Medin
    Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390 8542, USA
    Radiother Oncol 106:101-5. 2013
    ..This study was performed to test the hypothesis that spinal cord radiosensitivity is significantly modified by uniform versus laterally non-uniform dose distributions...
  7. doi request reprint Use of the BrainLAB ExacTrac X-Ray 6D system in image-guided radiotherapy
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Med Dosim 33:124-34. 2008
    ....
  8. ncbi request reprint Optimization of multi-slice helical respiration-correlated CT: the effects of table speed and rotation time
    Nicole M Wink
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Phys Med Biol 50:5717-29. 2005
    ....
  9. ncbi request reprint Targeting accuracy of an image guided gating system for stereotactic body radiotherapy
    Stephen E Tenn
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Phys Med Biol 50:5443-62. 2005
    ..5 +/- 0.2 mm for phantom rotations up to 5 degrees. We found and corrected a synchronization error caused by a faulty x-ray duration setting and detected a 60 +/- 20 ms time delay in our linear accelerator...
  10. ncbi request reprint A methodology for verification of radiotherapy dose calculation
    Nzhde Agazaryan
    Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California 90095 6951, USA
    J Neurosurg 101:356-61. 2004
    ..Dosimetric accuracy of clinically active intensity-modulated radiotherapy (IMRT) and intensity-modulated radiosurgery (IMRS) programs was assessed using this methodology...
  11. ncbi request reprint Stereotactic radiotherapy for treatment of cavernous sinus meningiomas
    Michael T Selch
    Department of Radiation Oncology, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA 90045 6951, USA
    Int J Radiat Oncol Biol Phys 59:101-11. 2004
    ..To assess the safety and efficacy of stereotactic radiotherapy (SRT) using a linear accelerator equipped with a micromultileaf collimator for cavernous sinus meningiomas...
  12. ncbi request reprint Comparison of transabdominal ultrasound and electromagnetic transponders for prostate localization
    Ryan D Foster
    Department of Radiation Oncology, UT Southwestern Medical Center at Dallas, Dallas, TX 75390 9183, USA
    J Appl Clin Med Phys 11:2924. 2010
    ..Our study finds that there are systematic differences between Calypso and ultrasound for prostate localization...
  13. ncbi request reprint A feasibility study of 18F-fluorodeoxyglucose positron emission tomography targeting and simultaneous integrated boost for intensity-modulated radiosurgery and radiotherapy
    Timothy D Solberg
    Department of Radiation Oncology, David Geffen School of Medicine, University of California, 90095 6951, USA
    J Neurosurg 101:381-9. 2004
    ....
  14. ncbi request reprint Functional stereotactic radiosurgery involving a dedicated linear accelerator and gamma unit: a comparison study
    Timothy D Solberg
    Department of Radiation Oncology, University of California, Los Angeles School of Medicine, Los Angeles 90095 6951, USA
    J Neurosurg 101:373-80. 2004
    ..The purpose of this work was to investigate the targeting and dosimetric characteristics of a linear accelerator (LINAC) system dedicated for stereotactic radiosurgery compared with those of a commercial gamma knife (GK) unit...
  15. ncbi request reprint The effects of tumor motion on planning and delivery of respiratory-gated IMRT
    Geoffrey D Hugo
    Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
    Med Phys 30:1052-66. 2003
    ..The utilization of gating for IMRT treatment, including imaging, planning, and delivery, significantly reduces the errors introduced by object motion...
  16. ncbi request reprint Dosimetric characteristics of a new linear accelerator under gated operation
    Sergey Kriminski
    Department of Radiation Oncology, David Geffen School of Medicine at University of California, Los Angeles, California 90095, USA
    J Appl Clin Med Phys 7:65-76. 2006
    ..Based on the comparison with widely accepted standards for conventional delivery, our results indicate that this LINAC is well suited for gated delivery of nondynamic fields...
  17. doi request reprint Dosimetric consequences of intrafraction prostate motion
    Haisen S Li
    Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA
    Int J Radiat Oncol Biol Phys 71:801-12. 2008
    ..To analyze characteristics of intrafraction prostate motion, monitored using the Calypso system, and investigate dosimetric consequences of the motion for different clinical target volume (CTV) to planning target volume (PTV) margins...
  18. ncbi request reprint Improvements in prostate brachytherapy dosimetry due to seed stranding
    Kevin Lin
    Department of Radiation Oncology, University of California, Los Angeles, CA 90095, USA
    Brachytherapy 6:44-8. 2007
    ..In order to contribute to the understanding of whether seed stranding improves dosimetry, we present retrospective data from our institution...
  19. ncbi request reprint Stereotactic radiotherapy for the treatment of lymphocytic hypophysitis. Report of two cases
    Michael T Selch
    Department of Radiation Oncology, Division of Neurological Surgery, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at the University of California at Los Angeles, California 90095 6951, USA
    J Neurosurg 99:591-6. 2003
    ....
  20. ncbi request reprint Respiratory correlated cone-beam computed tomography on an isocentric C-arm
    Sergey Kriminski
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Phys Med Biol 50:5263-80. 2005
    ..Images reconstructed from the retrospectively gated projection sequences using the optimal gating window data showed a significant improvement compared to images reconstructed from the complete projection datasets...
  21. pmc Spinal cord tolerance to single-fraction partial-volume irradiation: a swine model
    Paul M Medin
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Int J Radiat Oncol Biol Phys 79:226-32. 2011
    ..To determine the spinal cord tolerance to single-fraction, partial-volume irradiation in swine...
  22. ncbi request reprint A seed specific dose kernel method for low-energy brachytherapy dosimetry
    John J DeMarco
    Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
    J Appl Clin Med Phys 4:66-74. 2003
    ..Good agreement is achieved for a representative pre- and post-plan comparison versus a commercial implementation of the TG-43 brachytherapy dosimetry protocol...
  23. pmc Development of a locally advanced orthotopic prostate tumor model in rats for assessment of combined modality therapy
    Vasu Tumati
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Int J Oncol 42:1613-9. 2013
    ..This model recapitulates radiation-resistant prostate cancers which can be used to demonstrate and quantify therapeutic response to combined modality treatments...
  24. doi request reprint Multi-staged robotic stereotactic radiosurgery for large cerebral arteriovenous malformations
    Chuxiong Ding
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, USA Electronic address
    Radiother Oncol 109:452-6. 2013
    ..The treatment planning process and strategies to optimize both individual and composite dosimetry are discussed...
  25. doi request reprint Optimization of normalized prescription isodose selection for stereotactic body radiation therapy: conventional vs robotic linac
    Chuxiong Ding
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas Texas 75390, USA
    Med Phys 40:051705. 2013
    ..This work aims to determine the optimal prescription isodose line that minimizes normal tissue irradiation for stereotactic body radiation therapy (SBRT) for a conventional linear accelerator and a robotic delivery platform...
  26. pmc A comparison of radiographic techniques and electromagnetic transponders for localization of the prostate
    Ryan D Foster
    Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Radiat Oncol 7:101. 2012
    ..The aim of this study is to compare three methodologies of prostate localization and to determine if there are significant differences in the techniques...
  27. ncbi request reprint Initial clinical results of stereotactic radiotherapy for the treatment of craniopharyngiomas
    Michael T Selch
    Department of Radiation Oncology, School of Medicine, University of California, Los Angeles CA 90095, USA
    Technol Cancer Res Treat 1:51-9. 2002
    ..Further clinical experience is necessary to determine the clinical utility of beam shaping in the setting of SRT...
  28. ncbi request reprint High dose-per-fraction irradiation of limited lung volumes using an image-guided, highly focused irradiator: simulating stereotactic body radiotherapy regimens in a small-animal model
    Jaeho Cho
    Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75093, USA
    Int J Radiat Oncol Biol Phys 77:895-902. 2010
    ..Here, we describe such an irradiation system and use it to examine normal tissue toxicity in a small-animal model at lung volumes similar to those associated with human therapy...
  29. pmc Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation
    Shihong Ma
    Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
    PLoS ONE 8:e56607. 2013
    ....
  30. pmc A technique for pediatric total skin electron irradiation
    Qinan Bao
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, 5801 Forest Park Rd, Dallas, TX 75390, USA
    Radiat Oncol 7:40. 2012
    ..This work discusses the commissioning and quality assurance (QA) methods for implementing a modified Stanford technique using a rotating harness system to position sedated pediatric patients treated with electrons to the total skin...
  31. pmc Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation
    Kosho Yamanouchi
    Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Hepatology 49:258-67. 2009
    ..Thus, preparative HIR could be potentially useful to augment hepatocyte transplantation...
  32. pmc An athymic rat model of cutaneous radiation injury designed to study human tissue-based wound therapy
    Lucas H Rifkin
    1Department of Plastic and Reconstructive Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Radiat Oncol 7:68. 2012
    ..To describe a pilot study for a novel preclinical model used to test human tissue-based therapies in the setting of cutaneous radiation injury...
  33. ncbi request reprint Investigations of a minimally invasive method for treatment of spinal malignancies with LINAC stereotactic radiation therapy: accuracy and animal studies
    Paul M Medin
    Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA
    Int J Radiat Oncol Biol Phys 52:1111-22. 2002
    ..A new method for stereotactic irradiation of spinal malignancies is presented, with evaluations of the theoretic and practical limitations of localization accuracy and the implementation of the method in swine...
  34. ncbi request reprint Patient specific quality assurance for the delivery of intensity modulated radiotherapy
    Nzhde Agazaryan
    Department of Radiation Oncology, UCLA School of Medicine, 200 UCLA Medical Plaza, Suite B265, Los Angeles, California 90095 6951, USA
    J Appl Clin Med Phys 4:40-50. 2003
    ..Absolute dosimetry for each composite plan is performed using an ionization chamber. To date, excellent agreement between measurements and calculations has been observed...
  35. ncbi request reprint An evaluation of gating window size, delivery method, and composite field dosimetry of respiratory-gated IMRT
    Geoffrey D Hugo
    Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
    Med Phys 29:2517-25. 2002
    ..For multiple field IMRT delivery, the largest errors were generated in regions where high field modulation was present parallel to the axis of motion. Gating was found to reduce these large errors to clinically acceptable levels...
  36. ncbi request reprint A Monte Carlo based phase space model for quality assurance of intensity modulated radiotherapy incorporating leaf specific characteristics
    Randi F Aaronson
    Department of Radiation Oncology, University of California, Los Angeles, California 90095 6951, USA
    Med Phys 29:2952-8. 2002
    ..53 criteria for all benchmark fields used. Film dosimetry was used to evaluate the model for IMRT sequences and plans, and the ability of the model to account for leaf sequencing effects is also demonstrated...
  37. ncbi request reprint Absence of multiple local minima effects in intensity modulated optimization with dose-volume constraints
    Jorge Llacer
    EC Engineering Consultants, LLC 130, Forest Hill Drive, Los Gatos, CA 95032, USA
    Phys Med Biol 48:183-210. 2003
    ..The results of the latter two methods have only been discussed briefly, as they yielded the same conclusions as the NG method...
  38. ncbi request reprint Degeneracy, frequency response and filtering in IMRT optimization
    Jorge Llacer
    EC Engineering Consultants LLC, 130 Forest Hill Drive, Los Gatos, CA 95032, USA
    Phys Med Biol 49:2853-80. 2004
    ..Stopping points for the studied algorithms are discussed and the deterioration of DVH characteristics with filtering is shown to be partially recoverable by the use of space-variant filtering techniques...
  39. ncbi request reprint Experimental verification and clinical implementation of a commercial Monte Carlo electron beam dose calculation algorithm
    Margarida Fragoso
    University of Nebraska Medical Center, Omaha, Nebraska 68198 7521, USA
    Med Phys 35:1028-38. 2008
    ..3 cm. Timing values ranged from 2 min to 24.5 h, depending on the field size, beam energy, number, and thickness of computed tomography slices used to define the patient's anatomy for the overall uncertainty values mentioned above...
  40. ncbi request reprint Three-dimensional fast imaging employing steady-state acquisition magnetic resonance imaging for stereotactic radiosurgery of trigeminal neuralgia
    Gabriela del Rocío Chávez Chávez
    Division of Neurosurgery, University of California at Los Angeles, Los Angeles, California, USA
    Neurosurgery 56:E628; discussion E628. 2005
    ....
  41. ncbi request reprint Contrast-enhanced brachytherapy for prostate cancer
    Amos Norman
    Department of Radiation Oncology, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, USA
    Acad Radiol 9:S182-4. 2002
  42. ncbi request reprint Dosimetric parameters for three low-energy brachytherapy sources using the Monte Carlo N-particle code
    John J DeMarco
    Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095 6951, USA
    Med Phys 29:662-8. 2002
    ..Radial dose function, g(r), calculated to a distance of 10 cm, and an isotropy function, F(r, theta), calculated for radii from 0.5 to 7.0 cm, were found to be in close agreement with previously published data...
  43. ncbi request reprint An arteriovenous malformation model for stereotactic radiosurgery research
    Reza Jahan
    Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA
    Neurosurgery 61:152-9; discussion 159. 2007
    ..To introduce the utilization of a swine arteriovenous malformation (AVM) model for stereotactic radiosurgery research and to describe the morphological changes in the vessels after radiation...
  44. ncbi request reprint Image-guided radiotherapy using a mobile kilovoltage x-ray device
    Stephen P Sorensen
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA
    Med Dosim 31:40-50. 2006
    ..It was demonstrated that this could be improved by correlating the acquisition of individual 2D projections with respiration for retrospective reconstruction of phase-based volumetric datasets...
  45. ncbi request reprint Stereotactic radiosurgery of the rete mirabile in swine: a longitudinal study of histopathological changes
    Reza Jahan
    Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
    Neurosurgery 58:551-8; discussion 551-8. 2006
    ..The mechanisms of vessel occlusion in arteriovenous malformations has not been extensively evaluated. To better understand these mechanisms, we report histopathological changes in the swine rete mirabile after stereotactic radiosurgery...
  46. ncbi request reprint Dosimetric parameters of three new solid core I-125 brachytherapy sources
    Timothy D Solberg
    Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 98095 6951, USA
    J Appl Clin Med Phys 3:119-34. 2002
    ..All dosimetric parameters were found to be in close agreement with previously published data for similar source configurations. The MCNP Monte Carlo code appears to be ideally suited to low energy dosimetry applications...
  47. ncbi request reprint Phase versus amplitude sorting of 4D-CT data
    Nicole Wink
    Department of Radiation Oncology, David Geffen School of Medicine at University of California, Los Angeles, Peter Morton Medical Building, Suite B265, Los Angeles, California 90095 USA
    J Appl Clin Med Phys 7:77-85. 2006
    ..A 180 degrees interpolation was used for reconstruction after gating. Significant improvement using the amplitude-sorting technique was observed, particularly when testing nonperiodic motion functions...
  48. ncbi request reprint Intracranial stereotactic positioning systems: Report of the American Association of Physicists in Medicine Radiation Therapy Committee Task Group no. 68
    A W Lightstone
    Department of Medical Physics, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario M4N 3M5, Canada
    Med Phys 32:2380-98. 2005
    ....
  49. ncbi request reprint Stereotactic radiotherapy for the treatment of acoustic neuromas
    Michael T Selch
    Department of Radiation Oncology and Division of Neurosurgery, David Geffen School of Medicine, University of California, 90045 6951, USA
    J Neurosurg 101:362-72. 2004
    ..The authors sought to assess the safety and efficacy of stereotactic radiotherapy when using a linear accelerator equipped with a micromultileaf collimator for the treatment of patients with acoustic neuromas...