Francesco Sofi

Summary

Publications

  1. pmc Adherence to Mediterranean diet and health status: meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    BMJ 337:a1344. 2008
  2. doi request reprint Mediterranean diet and health
    Francesco Sofi
    Department of Clinical and Experimental Medicine, University of Florence, Italy
    Biofactors 39:335-42. 2013
  3. doi request reprint Characterization of Khorasan wheat (Kamut) and impact of a replacement diet on cardiovascular risk factors: cross-over dietary intervention study
    F Sofi
    Agency of Nutrition, Careggi University Hospital, Florence, Italy
    Eur J Clin Nutr 67:190-5. 2013
  4. doi request reprint The atherosclerotic risk profile is affected differently by fish flesh with a similar EPA and DHA content but different n-6/n-3 ratio
    Francesco Sofi
    Department of Clinica and Experimental Medicine, Thrombosis Centre, Florence, Italy
    Asia Pac J Clin Nutr 22:32-40. 2013
  5. doi request reprint Identification of change-points in the relationship between food groups in the Mediterranean diet and overall mortality: an 'a posteriori' approach
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, Florence, Italy
    Eur J Nutr 51:167-72. 2012
  6. ncbi request reprint Lifestyle modifications after acute coronary syndromes in a subset of the AMI-Florence 2 Registry
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    Acta Cardiol 66:791-6. 2011
  7. pmc A meta-analysis of potential risks of low levels of protein Z for diseases related to vascular thrombosis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Florence, Italy
    Thromb Haemost 103:749-56. 2010
  8. doi request reprint Physical activity during leisure time and primary prevention of coronary heart disease: an updated meta-analysis of cohort studies
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence, Italy
    Eur J Cardiovasc Prev Rehabil 15:247-57. 2008
  9. doi request reprint Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Florence, Italy
    Am J Clin Nutr 92:1189-96. 2010
  10. doi request reprint Residual platelet reactivity on aspirin therapy and recurrent cardiovascular events--a meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Int J Cardiol 128:166-71. 2008

Collaborators

Detail Information

Publications67

  1. pmc Adherence to Mediterranean diet and health status: meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    BMJ 337:a1344. 2008
    ..To systematically review all the prospective cohort studies that have analysed the relation between adherence to a Mediterranean diet, mortality, and incidence of chronic diseases in a primary prevention setting...
  2. doi request reprint Mediterranean diet and health
    Francesco Sofi
    Department of Clinical and Experimental Medicine, University of Florence, Italy
    Biofactors 39:335-42. 2013
    ..In the present review, we encompass the updated evidence of the beneficial effects of Mediterranean diet in the occurrence of major chronic degenerative diseases...
  3. doi request reprint Characterization of Khorasan wheat (Kamut) and impact of a replacement diet on cardiovascular risk factors: cross-over dietary intervention study
    F Sofi
    Agency of Nutrition, Careggi University Hospital, Florence, Italy
    Eur J Clin Nutr 67:190-5. 2013
    ..The objective was to characterise Kamut and to examine the effect of a replacement diet with their products on cardiovascular risk parameters...
  4. doi request reprint The atherosclerotic risk profile is affected differently by fish flesh with a similar EPA and DHA content but different n-6/n-3 ratio
    Francesco Sofi
    Department of Clinica and Experimental Medicine, Thrombosis Centre, Florence, Italy
    Asia Pac J Clin Nutr 22:32-40. 2013
    ..In conclusion, similar EPA+DHA content with different n- 6/n-3 ratio fish flesh intake was shown to have varied affects on lipid, inflammatory and haemorheological parameters in a group of healthy subjects...
  5. doi request reprint Identification of change-points in the relationship between food groups in the Mediterranean diet and overall mortality: an 'a posteriori' approach
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, Florence, Italy
    Eur J Nutr 51:167-72. 2012
    ..The aim of the present study was to identify change-points in the relationship between food groups composing Mediterranean diet and overall mortality...
  6. ncbi request reprint Lifestyle modifications after acute coronary syndromes in a subset of the AMI-Florence 2 Registry
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    Acta Cardiol 66:791-6. 2011
    ..The aim of this study was to evaluate the adherence to recommendations for secondary prevention of cardiovascular diseases in patients with acute coronary syndromes (ACS)...
  7. pmc A meta-analysis of potential risks of low levels of protein Z for diseases related to vascular thrombosis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Florence, Italy
    Thromb Haemost 103:749-56. 2010
    ..18, 95%CI 1.19-4.00; p=0.01). The results of this meta-analysis are consistent with a role for protein Z deficiency in thrombotic diseases, including arterial thrombosis, pregnancy complications and venous thromboembolism...
  8. doi request reprint Physical activity during leisure time and primary prevention of coronary heart disease: an updated meta-analysis of cohort studies
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence, Italy
    Eur J Cardiovasc Prev Rehabil 15:247-57. 2008
    ..The real magnitude of the association between physical activity during leisure time (LTPA) and primary prevention of coronary heart disease (CHD) has, however, not been completely defined...
  9. doi request reprint Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Florence, Italy
    Am J Clin Nutr 92:1189-96. 2010
    ..The Mediterranean diet has long been reported to be protective against the occurrence of several different health outcomes...
  10. doi request reprint Residual platelet reactivity on aspirin therapy and recurrent cardiovascular events--a meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Int J Cardiol 128:166-71. 2008
    ..The aim of this study was to systematically assess the relationship between RPR on acetylic salicylic acid (ASA) therapy and the occurrence of recurrent events in a meta-analysis of prospective studies...
  11. pmc Cardiovascular evaluation, including resting and exercise electrocardiography, before participation in competitive sports: cross sectional study
    Francesco Sofi
    Department of Medical and Surgical Critical Area, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    BMJ 337:a346. 2008
    ..To evaluate the clinical usefulness of complete preparticipation cardiovascular screening in a large cohort of sports participants...
  12. doi request reprint Effects of a 1-year dietary intervention with n-3 polyunsaturated fatty acid-enriched olive oil on non-alcoholic fatty liver disease patients: a preliminary study
    Francesco Sofi
    Regional Agency of Nutrition, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence, Italy
    Int J Food Sci Nutr 61:792-802. 2010
    ..The aim of our preliminary study was to evaluate the effectiveness of long-term consumption of food enriched with n-3 polyunsaturated fatty acids (PUFA) in patients with NAFLD...
  13. pmc Protein Z-dependent protease inhibitor and protein Z in peripheral arterial disease patients
    F Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Florence, Italy
    J Thromb Haemost 7:731-5. 2009
    ..The aim of this study was to more fully assess the protein Z-ZPI system in individuals with atherosclerosis selected by the presence of symptomatic PAD...
  14. doi request reprint Effects of short-term consumption of bread obtained by an old Italian grain variety on lipid, inflammatory, and hemorheological variables: an intervention study
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    J Med Food 13:615-20. 2010
    ..Short-term dietary intake of whole grain bread obtained from an old grain variety seems to impose a favorable status with regard to lower circulating levels of markers of atherosclerosis...
  15. doi request reprint Clopidogrel non-responsiveness and risk of cardiovascular morbidity. An updated meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Thromb Haemost 103:841-8. 2010
    ....
  16. doi request reprint Effectiveness of the Mediterranean diet: can it help delay or prevent Alzheimer's disease?
    Francesco Sofi
    Regional Centre of Nutrition, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    J Alzheimers Dis 20:795-801. 2010
    ..Moreover, the Mediterranean diet has been extensively reported to be associated with a favorable health outcome and a better quality of life...
  17. doi request reprint High lipoprotein (a) levels are associated with an increased risk of retinal vein occlusion
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Atherosclerosis 210:278-81. 2010
    ..The aim of this study was to investigate, in a large group of RVO patients, the role of such an emerging thrombophilic parameter on the pathogenesis of RVO...
  18. doi request reprint Dietary intake of trans fatty acids as a cardiovascular risk factor in a population of Italian teenagers
    Francesco Sofi
    Regional Agency of Nutrition, Azienda Ospedaliero Universitaria Careggi, University of Florence, Viale Morgagni 85, Florence, Italy
    Cardiol Young 19:589-93. 2009
    ....
  19. doi request reprint Cytochrome P450 2C19*2 polymorphism and cardiovascular recurrences in patients taking clopidogrel: a meta-analysis
    F Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Florence, Italy
    Pharmacogenomics J 11:199-206. 2011
    ....
  20. doi request reprint The Mediterranean diet revisited: evidence of its effectiveness grows
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    Curr Opin Cardiol 24:442-6. 2009
    ..The purpose of this review is to examine the evidence in support of the effectiveness of the Mediterranean diet in reducing the prevalence of cardiovascular and chronic disease and their associated risk factors...
  21. doi request reprint Effects of a dairy product (pecorino cheese) naturally rich in cis-9, trans-11 conjugated linoleic acid on lipid, inflammatory and haemorheological variables: a dietary intervention study
    F Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Florence, Italy
    Nutr Metab Cardiovasc Dis 20:117-24. 2010
    ....
  22. doi request reprint Lipid, inflammatory and haemorheological profiles are significantly affected by farmed fish eating: an intervention study
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, Florence, Italy
    Int J Food Sci Nutr 60:50-9. 2009
    ..The objective of the present study was to evaluate the influence of short-term dietary intake of farmed fish on biomarkers related to the atherosclerotic process...
  23. ncbi request reprint Role of haemorheological factors in patients with retinal vein occlusion
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Thromb Haemost 98:1215-9. 2007
    ..In conclusion, our data indicate that an alteration of haemorheological parameters may modulate the susceptibility to the RVO, by possibly helping to identify patients who may benefit from haemodilution...
  24. ncbi request reprint Low protein Z levels in patients with peripheral arterial disease
    Francesco Sofi
    Thrombosis Centre, Department of Medical and Surgical Critical Care, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Thromb Haemost 98:1114-7. 2007
    ..03). In conclusion, our data shows an association between low protein Z levels and the occurrence of PAD. These findings provide evidence for the role of protein Z in the pathogenesis of the atherosclerotic disease...
  25. ncbi request reprint Dietary habits, lifestyle and cardiovascular risk factors in a clinically healthy Italian population: the 'Florence' diet is not Mediterranean
    F Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, Florence, Italy
    Eur J Clin Nutr 59:584-91. 2005
    ....
  26. ncbi request reprint Thrombophilic risk factors for symptomatic peripheral arterial disease
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    J Vasc Surg 41:255-60. 2005
    ..The aim of this study was to determine an extended thrombophilic risk profile of patients with symptomatic PAD...
  27. ncbi request reprint Adherence to a healthful life attenuates lipid parameters among a healthy Italian population
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Nutr Metab Cardiovasc Dis 17:642-8. 2007
    ....
  28. ncbi request reprint Protein Z plasma levels in different phases of activity of coronary atherosclerosis
    F Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    J Thromb Haemost 3:2254-8. 2005
    ..1-8.9, P = 0.02). In conclusion, these results strengthen our previous data on low protein Z plasma levels in ACS and indicate a possible dose-response effect of decreasing protein Z plasma levels on the coronary atherosclerotic disease...
  29. doi request reprint Physical activity and risk of cognitive decline: a meta-analysis of prospective studies
    F Sofi
    Don Carlo Gnocchi Foundation, Centro S Maria agli Ulivi, Onlus IRCCS, Italy
    J Intern Med 269:107-17. 2011
    ..We performed a systematic meta-analysis of all the available prospective studies that investigated the association between physical activity and risk of cognitive decline in nondemented subjects...
  30. ncbi request reprint High levels of homocysteine, lipoprotein (a) and plasminogen activator inhibitor-1 are present in patients with abdominal aortic aneurysm
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Thromb Haemost 94:1094-8. 2005
    ..13; p = 0.005). In conclusion, a significant association between abnormal levels of some metabolic parameters related to thrombosis such as Hcy, Lp(a) and PAI-1 and AAA has been observed...
  31. ncbi request reprint Protein Z: "light and shade" of a new thrombotic factor
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    Clin Lab 50:647-52. 2004
    ..Most of these studies were performed on ischemic vascular diseases. Recently, the possible role of protein Z deficiency in the occurrence of cardiovascular diseases has been evaluated...
  32. ncbi request reprint Low adherence of a clinically healthy Italian population to nutritional recommendations for primary prevention of chronic diseases
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Nutr Metab Cardiovasc Dis 16:436-44. 2006
    ..The aims of this study were to evaluate dietary habits, and to assess the adherence of the general population to the recommendations for correct nutritional behaviour...
  33. ncbi request reprint Protein Z levels and prognosis in patients with acute coronary syndromes
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Florence, Italy
    Clin Chem Lab Med 44:1098-102. 2006
    ..The aims of this study were to test changes in protein Z and their association with outcome at 1-year follow-up in 193 (150 male, 43 female) patients with ACS...
  34. ncbi request reprint Adaptive physical activity and back pain: a non-randomised community-based intervention trial
    F Sofi
    Department of Medical and Surgical Critical Care, University of Florence, Italy
    Eur J Phys Rehabil Med 47:543-9. 2011
    ..Back pain is a significant problem due to the high healthcare utilization, rising costs of care and low effectiveness of many current treatments...
  35. ncbi request reprint Low vitamin B6 and folic acid levels are associated with retinal vein occlusion independently of homocysteine levels
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Atherosclerosis 198:223-7. 2008
    ..In conclusion, the present study documents, on a large sample of patients, that low vitamin B6 levels, low folic acid levels and elevated Hcy levels are each independently associated with RVO...
  36. ncbi request reprint Lipoprotein (a) and venous thromboembolism in adults: a meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    Am J Med 120:728-33. 2007
    ..The aim of this article is to systematically examine the published data on the association between high Lp(a) levels and venous thromboembolism...
  37. ncbi request reprint Fish intake and LPA 93C>T polymorphism: gene-environment interaction in modulating lipoprotein (a) concentrations
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    Atherosclerosis 195:e147-54. 2007
    ..In conclusion, this study reported a significant interaction of daily fish intake and LPA 93C>T polymorphism in decreasing Lp(a) concentrations...
  38. ncbi request reprint Coffee consumption and risk of coronary heart disease: a meta-analysis
    Francesco Sofi
    Department of Medical and Surgical Critical Care and Center for the Study at Molecular and Clinical Level of Chronic, Degenerative and Neoplastic Diseases to Develop Novel Therapies, University of Florence, Florence, Italy
    Nutr Metab Cardiovasc Dis 17:209-23. 2007
    ..The aim of this study was to systematically examine the data published on the association between habitual coffee consumption and risk of CHD...
  39. doi request reprint eNOS and ACE genes influence peripheral arterial disease predisposition in smokers
    Elena Sticchi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    J Vasc Surg 52:97-102.e1. 2010
    ..In this study, we evaluated the role of eNOS-786T>C, -894G>T and 4a/4b polymorphisms as markers of PAD per se and in the presence of the ACE D allele in patients previously investigated...
  40. doi request reprint Multilocus analysis in candidate genes ACE, AGT, and AGTR1 and predisposition to peripheral arterial disease: role of ACE D/-240T haplotype
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    J Vasc Surg 50:1399-404. 2009
    ..This study investigated four polymorphisms in angiotensinogen (AGT), angiotensin converting enzyme (ACE), and angiotensin II receptor type 1 (AGTR1), genes of RAS, in both predicting PAD and modulating the severity of the disease...
  41. ncbi request reprint Endothelial nitric oxide synthase -786T>C, but not 894G>T and 4a4b, polymorphism influences plasma homocysteine concentrations in persons with normal vitamin status
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy
    Clin Chem 51:1159-64. 2005
    ..The aim of this study was to investigate the role of endothelial nitric oxide synthase (eNOS) -786T>C, 894G>T, and 4a4b polymorphisms in influencing Hcy concentrations...
  42. doi request reprint Atherosclerotic and thrombophilic risk factors in patients with ischemic central retinal vein occlusion
    Andrea Sodi
    Eye Clinic, University of Florence, Florence, Italy
    Retina 31:724-9. 2011
    ..To investigate atherosclerotic and thrombophilic risk factors in patients affected by acute ischemic and nonischemic central retinal vein occlusions (CRVOs)...
  43. doi request reprint Association between polymorphisms of the renin angiotensin system and carotid stenosis
    Elena Sticchi
    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy
    J Vasc Surg 54:467-73. 2011
    ....
  44. doi request reprint Relationship between blood viscosity and infarct size in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
    Emanuele Cecchi
    Dipartimento di Area Critica Medico Chirurgica, Centro Trombosi, Azienda Ospedaliero Universitaria Careggi, Firenze, Italy
    Int J Cardiol 134:189-94. 2009
    ....
  45. doi request reprint Polymorphisms of genes involved in extracellular matrix remodeling and abdominal aortic aneurysm
    Claudia Saracini
    Department of Medical and Surgical Critical Care, University of Florence, Atherothrombotic Diseases Center, Florence, Italy
    J Vasc Surg 55:171-179.e2. 2012
    ..Abdominal aortic aneurysm (AAA) has a multifactorial etiology and the relevance of genetic factors is getting increasing interest, in particular those related to the destructive remodeling of extracellular matrix...
  46. doi request reprint Postacute rehabilitation after coronary surgery: the effect of preoperative physical activity on the incidence of paroxysmal atrial fibrillation
    Marzia Giaccardi
    Cardiac Rehabilitation Unit, Don Gnocchi Foundation, Florence, Italy
    Am J Phys Med Rehabil 90:308-15. 2011
    ..In this study, we hypothesized that moderate-intensity physical activity in the year before surgery might favorably affect the incidence of AF during postacute rehabilitation...
  47. doi request reprint ACE and TGFBR1 genes interact in influencing the susceptibility to abdominal aortic aneurysm
    Laura Lucarini
    Department of Medical and Surgical Critical Care, University of Florence, Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Atherosclerosis 202:205-10. 2009
    ..01]. This study, which demonstrates an interaction between ACE and TGFBR1 genes in predisposing to AAA, may provide further information on the mechanisms contributing to AAA susceptibility, and offer a topic for future larger studies...
  48. doi request reprint Evaluation of traditional and emerging cardiovascular risk factors in patients with non-arteritic anterior ischemic optic neuropathy: a case-control study
    Barbara Giambene
    Eye Clinic, University of Florence, Viale Morgagni, 85 50134, Florence, Italy
    Graefes Arch Clin Exp Ophthalmol 247:693-7. 2009
    ..This study aims at evaluating the role of traditional and emerging cardiovascular risk factors on the development of NAION...
  49. pmc Predictors of vitamin B6 and folate concentrations in older persons: the InCHIANTI study
    Anna Maria Gori
    Department of Medical and Surgical Critical Care, Multidisciplinary Centre of Research on Food Sciences G R A, University of Florence, Florence, Italy
    Clin Chem 52:1318-24. 2006
    ....
  50. doi request reprint Physical activity and circulating endothelial progenitor cells: an intervention study
    Francesca Cesari
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Florence, Italy
    Eur J Clin Invest 42:927-32. 2012
    ..To assess the effect of a personalized physical activity programme on weight and circulating (CPC) and endothelial progenitor cells (EPC) in overweight and obese subjects...
  51. ncbi request reprint eNOS G894T polymorphism as a mild predisposing factor for abdominal aortic aneurysm
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, University of Florence, Thrombosis Centre, Italy
    J Vasc Surg 42:415-9. 2005
    ..No information is available about the influence of the eNOS gene T-786C, G894T, and 4a/4b polymorphisms in the susceptibility to the disease...
  52. ncbi request reprint Analysis of minK and eNOS genes as candidate loci for predisposition to non-valvular atrial fibrillation
    Cinzia Fatini
    Department of Medical and Surgical Critical Care Thrombosis Centre, Azienda Ospedaliero Universitaria, University of Florence, Viale Morgagni 85, 50134, Italy
    Eur Heart J 27:1712-8. 2006
    ..We evaluated the role of eNOS -786T>C, 894G>T, 4a/4b and of minK S38G polymorphisms as predisposing factors to non-valvular atrial fibrillation (NVAF)...
  53. doi request reprint Comparison of hemorheological variables in ST-elevation myocardial infarction versus those in non-ST-elevation myocardial infarction or unstable angina pectoris
    Emanuele Cecchi
    Dipartimento di Area Critica Medico Chirurgica, Centro Trombosi, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Am J Cardiol 102:125-8. 2008
    ....
  54. ncbi request reprint Low protein Z plasma levels are independently associated with acute coronary syndromes
    Sandra Fedi
    Department of Medical and Surgical Critical Care, Section of Clinical Medicine and Cardiology, University of Florence, and Thrombosis Center, Azienda Ospedaliera Careggi, viale G Morgagni 85, 50134 Florence, Italy
    Thromb Haemost 90:1173-8. 2003
    ..The contemporary presence of low PZ levels and smoking habit leads to an increased risk of ACS (OR=9.5; 99%CI 2.4-37.2; p < 0.0001). In conclusion, our results suggest a possible role of PZ in the occurrence of arterial thrombosis...
  55. ncbi request reprint Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, T-786C) and hyperhomocysteinemia on the predisposition to acute coronary syndromes
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Section of Clinical Medicine and Cardiology, Thrombosis Centre, Azienda Ospedaliera Careggi, Florence, Italy
    Am Heart J 147:516-21. 2004
    ..In this study we investigated the role of endothelial nitric oxide synthase (eNOS) polymorphisms as predisposing factors to acute coronary syndromes (ACS)...
  56. ncbi request reprint Relationship between exercise capacity, endothelial progenitor cells and cytochemokines in patients undergoing cardiac rehabilitation
    Francesca Cesari
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Viale Morgagni 85, 50134 Florence, Italy
    Thromb Haemost 101:521-6. 2009
    ..Finally, CD34+/KDR+ EPCs showed significant correlation with IL-8 at T1. In conclusion, a short period of CR intervention determines a different pattern of modifications for EPCs in relation to the improvement of exercise capacity...
  57. ncbi request reprint A proinflammatory state is associated with hyperhomocysteinemia in the elderly
    Anna Maria Gori
    Department of Medical and Surgical Critical Area, Center for the Study at Molecular and Clinical Level of Chronic, Degenerative and Neoplastic Diseases to Develop Novel Therapies, University of Florence, Florence, Italy
    Am J Clin Nutr 82:335-41. 2005
    ..A proinflammatory state is related to atherosclerosis, and recent studies suggest that acute phase reactants correlate with circulating concentrations of homocysteine...
  58. ncbi request reprint [Which diet for an effective cardiovascular prevention?]
    Francesco Sofi
    Department of Medical and Surgical Critical Care, University of Florence, Italy
    Monaldi Arch Chest Dis 78:60-5. 2012
    ....
  59. ncbi request reprint Association between homocysteine, vitamin B(6) concentrations and inflammation
    Anna Maria Gori
    Department of Medical and Surgical Critical Care, University of Florence, DeNOTHE Centre for the Study at Molecular and Clinical Level of Chronic, University of Florence, Florence, Italy
    Clin Chem Lab Med 45:1728-36. 2007
    ..This association, independent of the leading factor, may explain, at least in part, why subjects with high concentrations of Hcy and low concentrations of vitamin B(6) have a high risk of developing cardiovascular diseases...
  60. doi request reprint One-year adherence to exercise in elderly patients receiving postacute inpatient rehabilitation after cardiac surgery
    Claudio Macchi
    Cardiac Rehabilitation Unit, University of Florence, Florence, Italy
    Am J Phys Med Rehabil 88:727-34. 2009
    ..However, information on the effectiveness of cardiac rehabilitation in promoting lifestyle changes in elderly patients is still scant...
  61. doi request reprint Insomnia and risk of cardiovascular disease: a meta-analysis
    Francesco Sofi
    Don Carlo Gnocchi Foundation, Centro S Maria agli Ulivi, Onlus IRCCS, Florence, Italy
    Eur J Prev Cardiol 21:57-64. 2014
    ..We performed a systematic review with meta-analysis of all the available prospective studies that investigated the association between insomnia and risk of developing and/or dying from cardiovascular disease...
  62. doi request reprint Impact of a cardiac rehabilitation program and inflammatory state on endothelial progenitor cells in acute coronary syndrome patients
    Francesca Cesari
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Int J Cardiol 167:1854-9. 2013
    ..However not all patients respond to CR with an increase of EPC. We performed this study to identify the characteristics of patients who will not benefit from an increase of EPCs at the end of a CR program...
  63. doi request reprint Effects of de-alcoholised wines with different polyphenol content on DNA oxidative damage, gene expression of peripheral lymphocytes, and haemorheology: an intervention study in post-menopausal women
    Lisa Giovannelli
    Department of Preclinical and Clinical Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy
    Eur J Nutr 50:19-29. 2011
    ..The present intervention study was undertaken to evaluate the in vivo effects of wine polyphenols on gene expression in humans, along with their supposed antioxidant activity...
  64. doi request reprint Peripheral-arterial tonometry for assessing endothelial function in relation to dietary habits
    Gabriele Cioni
    Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
    J Investig Med 61:867-71. 2013
    ....
  65. ncbi request reprint Relation of inflammatory status to major adverse cardiac events and reverse remodeling in patients undergoing cardiac resynchronization therapy
    Antonio Michelucci
    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy
    J Card Fail 13:207-10. 2007
    ....
  66. doi request reprint Retinal vein occlusions: a review for the internist
    Rossella Marcucci
    Department of Medical and Surgical Critical Area, University of Florence, Florence, Italy
    Intern Emerg Med 6:307-14. 2011
    ..No data are available on the possible role of antithrombotic strategies in the long-term prevention of recurrent RVO or vascular events...
  67. ncbi request reprint Role of endothelin-1 in exposure to high altitude: Acute Mountain Sickness and Endothelin-1 (ACME-1) study
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Circulation 114:1410-6. 2006
    ..The aim of the present study was to investigate the effects of ET-1 antagonism on pulmonary hypertension, renal water, and sodium balance under acute and prolonged exposure to high-altitude-associated hypoxia...