David A Snowdon

Summary

Publications

  1. pmc Neuropathological findings processed by artificial neural networks (ANNs) can perfectly distinguish Alzheimer's patients from controls in the Nun Study
    Enzo Grossi
    Bracco SpA Medical Department, Milan, Italy
    BMC Neurol 7:15. 2007
  2. ncbi request reprint Healthy aging and dementia: findings from the Nun Study
    David A Snowdon
    Sanders Brown Center on Aging, 320 Health Sciences Building, University of Kentucky, Lexington, KY 40536 0200, USA
    Ann Intern Med 139:450-4. 2003
  3. ncbi request reprint Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study
    Kathryn P Riley
    Sanders Brown Center on Aging, Department of Preventive Medicine, University of Kentucky, Lexington, KY 40536, USA
    Ann Neurol 51:567-77. 2002
  4. ncbi request reprint Early life linguistic ability, late life cognitive function, and neuropathology: findings from the Nun Study
    Kathryn P Riley
    Department of Preventive Medicine, University of Kentucky, Lexington, KY 40536, USA
    Neurobiol Aging 26:341-7. 2005
  5. ncbi request reprint Head circumference, education and risk of dementia: findings from the Nun Study
    James A Mortimer
    Institute on Aging, University of South Florida, Tampa, FL 33612 3899, USA
    J Clin Exp Neuropsychol 25:671-9. 2003
  6. pmc Very early detection of Alzheimer neuropathology and the role of brain reserve in modifying its clinical expression
    James A Mortimer
    Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL 33612 3899, USA
    J Geriatr Psychiatry Neurol 18:218-23. 2005
  7. pmc Transitions to mild cognitive impairments, dementia, and death: findings from the Nun Study
    Suzanne L Tyas
    Department of Health Studies and Gerontology, University of Waterloo, Waterloo, Ontario, Canada
    Am J Epidemiol 165:1231-8. 2007
  8. pmc Healthy ageing in the Nun Study: definition and neuropathologic correlates
    Suzanne L Tyas
    Department of Health Studies and Gerontology, University of Waterloo, Waterloo, Ontario, Canada
    Age Ageing 36:650-5. 2007
  9. doi request reprint Small head circumference is associated with less education in persons at risk for Alzheimer disease in later life
    James A Mortimer
    Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL 33612 3805, USA
    Alzheimer Dis Assoc Disord 22:249-54. 2008

Detail Information

Publications9

  1. pmc Neuropathological findings processed by artificial neural networks (ANNs) can perfectly distinguish Alzheimer's patients from controls in the Nun Study
    Enzo Grossi
    Bracco SpA Medical Department, Milan, Italy
    BMC Neurol 7:15. 2007
    ..The aim of this study is to discover the hidden and non-linear associations among AD pathognomonic brain lesions and the clinical diagnosis of AD in participants in the Nun Study through Artificial Neural Networks (ANNs) analysis..
  2. ncbi request reprint Healthy aging and dementia: findings from the Nun Study
    David A Snowdon
    Sanders Brown Center on Aging, 320 Health Sciences Building, University of Kentucky, Lexington, KY 40536 0200, USA
    Ann Intern Med 139:450-4. 2003
    ..These case histories provide examples of how healthy aging and dementia relate to the degree of pathology present in the brain and the level of resistance to the clinical expression of the neuropathology...
  3. ncbi request reprint Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study
    Kathryn P Riley
    Sanders Brown Center on Aging, Department of Preventive Medicine, University of Kentucky, Lexington, KY 40536, USA
    Ann Neurol 51:567-77. 2002
    ..Additional studies are needed to help explain the variability in neuropathologic findings seen in individuals whose cognitive performance falls between intact function and dementia...
  4. ncbi request reprint Early life linguistic ability, late life cognitive function, and neuropathology: findings from the Nun Study
    Kathryn P Riley
    Department of Preventive Medicine, University of Kentucky, Lexington, KY 40536, USA
    Neurobiol Aging 26:341-7. 2005
    ..Low idea density also was significantly associated with lower brain weight, higher degree of cerebral atrophy, more severe neurofibrillary pathology, and the likelihood of meeting neuropathologic criteria for Alzheimer's disease...
  5. ncbi request reprint Head circumference, education and risk of dementia: findings from the Nun Study
    James A Mortimer
    Institute on Aging, University of South Florida, Tampa, FL 33612 3899, USA
    J Clin Exp Neuropsychol 25:671-9. 2003
    ..The findings suggest that higher education and larger head size, alone or in combination, may reduce the risk of expressing dementia in late life...
  6. pmc Very early detection of Alzheimer neuropathology and the role of brain reserve in modifying its clinical expression
    James A Mortimer
    Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL 33612 3899, USA
    J Geriatr Psychiatry Neurol 18:218-23. 2005
    ..Findings are presented showing the importance of higher education and larger brain size in masking the underlying disease pathology...
  7. pmc Transitions to mild cognitive impairments, dementia, and death: findings from the Nun Study
    Suzanne L Tyas
    Department of Health Studies and Gerontology, University of Waterloo, Waterloo, Ontario, Canada
    Am J Epidemiol 165:1231-8. 2007
    ..Thus, risk factors for dementia may operate primarily by predisposing individuals to develop mild cognitive impairments; subsequent progression to dementia then depends on only time and competing mortality...
  8. pmc Healthy ageing in the Nun Study: definition and neuropathologic correlates
    Suzanne L Tyas
    Department of Health Studies and Gerontology, University of Waterloo, Waterloo, Ontario, Canada
    Age Ageing 36:650-5. 2007
    ..Although the concept of healthy ageing has stimulated considerable interest, no generally accepted definition has been developed nor has its biological basis been determined...
  9. doi request reprint Small head circumference is associated with less education in persons at risk for Alzheimer disease in later life
    James A Mortimer
    Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL 33612 3805, USA
    Alzheimer Dis Assoc Disord 22:249-54. 2008
    ..These findings suggest that small HC limits educational attainment only among individuals who have greater risk of AD owing to their APOE genotype or who are destined to develop this illness later in life...