Mario Poljak

Summary

Affiliation: University of Ljubljana
Country: Slovenia

Publications

  1. pmc Characterization of novel cutaneous human papillomavirus genotypes HPV-150 and HPV-151
    Anja Kovanda
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    PLoS ONE 6:e22529. 2011
  2. pmc Characterization of a novel cutaneous human papillomavirus genotype HPV-125
    Anja Kovanda
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    PLoS ONE 6:e22414. 2011
  3. ncbi request reprint Human papillomavirus prevalence and type-distribution, cervical cancer screening practices and current status of vaccination implementation in Central and Eastern Europe
    Mario Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia Electronic address
    Vaccine 31:H59-70. 2013
  4. ncbi request reprint Vaccination indications and limits in the elderly
    Tina K Triglav
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia Corresponding author
    Acta Dermatovenerol Alp Pannonica Adriat 22:65-70. 2013
  5. pmc Limited cross-border infections in patients newly diagnosed with HIV in Europe
    Dineke Frentz
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Retrovirology 10:36. 2013
  6. pmc HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics
    Ana B Abecasis
    Unidade de Saúde Pública Internacional e Bioestatística, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal
    Retrovirology 10:7. 2013
  7. pmc Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients
    Kristof Theys
    Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium
    Retrovirology 9:81. 2012
  8. ncbi request reprint The Abbott RealTime High Risk HPV test is a clinically validated human papillomavirus assay for triage in the referral population and use in primary cervical cancer screening in women 30 years and older: a review of validation studies
    Mario Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloska 4, SI 1000 Ljubljana, Slovenia
    Acta Dermatovenerol Alp Panonica Adriat 22:43-7. 2013
  9. ncbi request reprint Cervical cancer screening practices in central and eastern Europe in 2012
    Polona J Maver
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 22:7-19. 2013
  10. doi request reprint Prophylactic human papillomavirus vaccination and primary prevention of cervical cancer: issues and challenges
    M Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Clin Microbiol Infect 18:64-9. 2012

Detail Information

Publications125 found, 100 shown here

  1. pmc Characterization of novel cutaneous human papillomavirus genotypes HPV-150 and HPV-151
    Anja Kovanda
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    PLoS ONE 6:e22529. 2011
    ..A partial L1 sequence of a putative novel HPV genotype, related to HPV-150, was identified in a squamous cell carcinoma of the skin obtained from a 64-year old immuno-compromised male patient...
  2. pmc Characterization of a novel cutaneous human papillomavirus genotype HPV-125
    Anja Kovanda
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    PLoS ONE 6:e22414. 2011
    ....
  3. ncbi request reprint Human papillomavirus prevalence and type-distribution, cervical cancer screening practices and current status of vaccination implementation in Central and Eastern Europe
    Mario Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia Electronic address
    Vaccine 31:H59-70. 2013
    ..Updates of the progress in the field are presented in a separate monograph entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012. ..
  4. ncbi request reprint Vaccination indications and limits in the elderly
    Tina K Triglav
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia Corresponding author
    Acta Dermatovenerol Alp Pannonica Adriat 22:65-70. 2013
    ..Maintaining the health of the population requires moving from a childhood-based vaccination strategy to a more balanced vaccination program throughout life. ..
  5. pmc Limited cross-border infections in patients newly diagnosed with HIV in Europe
    Dineke Frentz
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Retrovirology 10:36. 2013
    ..In this study, phylogenetic associations among HIV of newly diagnosed patients were determined across Europe...
  6. pmc HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics
    Ana B Abecasis
    Unidade de Saúde Pública Internacional e Bioestatística, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal
    Retrovirology 10:7. 2013
    ..Sequence variation may affect antiviral drug resistance development, disease progression, evolutionary rates and transmission routes...
  7. pmc Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients
    Kristof Theys
    Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium
    Retrovirology 9:81. 2012
    ....
  8. ncbi request reprint The Abbott RealTime High Risk HPV test is a clinically validated human papillomavirus assay for triage in the referral population and use in primary cervical cancer screening in women 30 years and older: a review of validation studies
    Mario Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloska 4, SI 1000 Ljubljana, Slovenia
    Acta Dermatovenerol Alp Panonica Adriat 22:43-7. 2013
    ..The test was launched on the European market in January 2009 and is currently used in many laboratories worldwide for routine detection of HPV...
  9. ncbi request reprint Cervical cancer screening practices in central and eastern Europe in 2012
    Polona J Maver
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 22:7-19. 2013
    ..Encouragingly, even in the countries where only opportunistic screening is performed, well-prepared plans and strategies have been established for switching to organized screening in the near future...
  10. doi request reprint Prophylactic human papillomavirus vaccination and primary prevention of cervical cancer: issues and challenges
    M Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Clin Microbiol Infect 18:64-9. 2012
    ..Several second-generation prophylactic vaccines are being developed with the aim of resolving some of the limitations of the two current HPV prophylactic vaccines...
  11. doi request reprint Nucleic acid tests for the detection of alpha human papillomaviruses
    Mario Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Vaccine 30:F100-6. 2012
    ..This article forms part of a special supplement entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012...
  12. ncbi request reprint Review of 20 years of HPV research in Slovenia
    Mario Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 20:99-112. 2011
    ....
  13. pmc Comparison of clinical and analytical performance of the Abbott Realtime High Risk HPV test to the performance of hybrid capture 2 in population-based cervical cancer screening
    Mario Poljak
    Faculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana Zaloška 4, 1000 Ljubljana, Slovenia
    J Clin Microbiol 49:1721-9. 2011
    ..RealTime can be considered to be a reliable and robust HPV assay clinically comparable to hc2 for the detection of CIN2+ lesions in a population-based cervical cancer screening setting...
  14. doi request reprint Commercially available assays for multiplex detection of alpha human papillomaviruses
    Mario Poljak
    University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Zaloska 4, 1105 Ljubljana, Slovenia
    Expert Rev Anti Infect Ther 8:1139-62. 2010
    ..Automation, price reduction and improvement of clinical specificity are the main goals for the future development of HPV assays...
  15. ncbi request reprint The Abbott RealTime High Risk HPV test: comparative evaluation of analytical specificity and clinical sensitivity for cervical carcinoma and CIN 3 lesions with the Hybrid Capture 2 HPV DNA test
    Mario Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, Zaloska 4, 1000 Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 18:94-103. 2009
    ..The Abbott RealTime High Risk HPV test (RealTime) is a novel assay designed to detect 14 high-risk human papillomavirus genotypes (hr-HPV) and concurrently distinguish HPV-16 and HPV-18 from other hr-HPV within a single test...
  16. ncbi request reprint Retrospective and prospective evaluation of the Amplicor HPV test for detection of 13 high-risk human papillomavirus genotypes on 862 clinical samples
    M Poljak
    Institute of Microbiology and Immunology, Medical Faculty, Zaloska 4, 1000 Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 14:147-52. 2005
    ..As a consequence, HPV testing has recently become an important part of the cervical carcinoma screening and detection algorithms...
  17. pmc Human papillomavirus genotype specificity of hybrid capture 2 low-risk probe cocktail
    Mario Poljak
    Institute of Microbiology and Immunology, University of Ljubljana, Slovenia
    J Clin Microbiol 47:2611-5. 2009
    ..A total of 8.4% of positive results, usually weak, were due to cross-reactivity with high-risk genotypes. Establishment of a gray zone is recommended...
  18. doi request reprint Anogenital hairs are an important reservoir of alpha-papillomaviruses in patients with genital warts
    Mario Poljak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Infect Dis 199:1270-4. 2009
    ..Having GWs was found to be strongly associated with the presence in anogenital hairs of the HPV genotype causing the GWs (range of odds ratios, 13.0-20.0)...
  19. pmc GeneXpert enterovirus assay: one-year experience in a routine laboratory setting and evaluation on three proficiency panels
    Katja Seme
    Institute of Microbiology and Immunology, Faculty of Medicine, Zaloska 4, Ljubljana 1000, Slovenia
    J Clin Microbiol 46:1510-3. 2008
    ..0% and 97.6%, respectively, for the Argene enterovirus consensus kit; and 100% and 100%, respectively, for an in-house real-time PCR. The initial and resolved specificities were 100% for all three assays...
  20. doi request reprint 2008 European Guideline on HIV testing
    M Poljak
    Faculty of Medicine, Institute of Microbiology and Immunology, University of Liubljana, Zatoska 4, 1000, Ljubljana, Slovenia
    Int J STD AIDS 20:77-83. 2009
    ..Its aim is to provide practical guidance to clinicians in these settings who undertake HIV testing and suggest appropriate standards for the audit of service provision...
  21. ncbi request reprint Hybrid Capture II HPV Test detects at least 15 human papillomavirus genotypes not included in its current high-risk probe cocktail
    Mario Poljak
    Institute of Microbiology and Immunology, Medical Faculty, Zaloska 4, 1000 Ljubljana, Slovenia
    J Clin Virol 25:S89-97. 2002
    ..At present, HCII is the only commercially available HPV assay with sufficient scientific data to support its performance in the clinical setting...
  22. ncbi request reprint Second-generation Hybrid capture test and Amplicor monitor test generate highly correlated hepatitis B virus DNA levels
    M Poljak
    Medical Faculty of Ljubljana, Institute of Microbiology and Immunology, Zaloska 4, 1105, Ljubljana, Slovenia
    J Virol Methods 97:165-9. 2001
    ..976, P<0.0001). The results of the study show that Hybrid capture II and Cobas-HBV could be used equally in the management for patients with chronic HBV infection...
  23. ncbi request reprint Beta-papillomaviruses in anogenital hairs plucked from healthy individuals
    Marko Potocnik
    Department of Dermatovenereology, University Medical Centre Ljubljana, Ljubljana, Slovenia
    J Med Virol 78:1673-8. 2006
    ..Beta-HPV genotype HPV-38 was detected most frequently, followed by HPV-36, HPV-15, and HPV-14D. In addition to the beta-HPV recognized officially five partial DNA sequences suggesting putative new HPV genotypes were identified...
  24. doi request reprint Digene HPV Genotyping RH Test RUO: comparative evaluation with INNO-LiPA HPV Genotyping Extra Test for detection of 18 high-risk and probable high-risk human papillomavirus genotypes
    Katja Seme
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Clin Virol 46:176-9. 2009
    ....
  25. ncbi request reprint Genomic diversity of low-risk human papillomavirus genotypes HPV 40, HPV 42, HPV 43, and HPV 44
    Polona J Maver
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Med Virol 86:272-82. 2014
    ..A similar level of genomic diversity of HPV 44 and its subtype was identified in our geographic region as has been reported previously on isolates collected worldwide...
  26. doi request reprint Tumor-specific and gender-specific pre-vaccination distribution of human papillomavirus types 6 and 11 in anogenital warts and laryngeal papillomas: a study on 574 tissue specimens
    Kristina Fujs Komlos
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Med Virol 84:1233-41. 2012
    ..0% vs. 59.2%; P = 0.000013), whereas HPV-11 was statistically more frequent in laryngeal papillomas than in anogenital warts (28.9% vs. 12.4%; P = 0.00003)...
  27. doi request reprint Genomic diversity of human papillomavirus (HPV) genotype 38
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Med Virol 81:288-95. 2009
    ..Taking into account the results of this and previous studies, at least seventeen HPV 38 genomic variants exist today, 12 of which are described for the first time in this study...
  28. ncbi request reprint Hepatitis C virus genotypes in 1,504 patients in Slovenia, 1993-2007
    Katja Seme
    Faculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana, Ljubljana, Slovenia
    J Med Virol 81:634-9. 2009
    ..28 [95% CI, 2.18-4.95]; P < 0.0001). During the 15-year period, the proportion of genotype 3 increased substantially, reflecting the fact that the HCV epidemic in Slovenia is driven mostly by intravenous drug use...
  29. ncbi request reprint Low prevalence of hepatitis B and C infections among HIV-infected individuals in Slovenia: a nation-wide study, 1986-2008
    Katja Seme
    Institute of Microbiology and Immunology, Faculty of Medicine, Zaloska 4, 1000 Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 18:153-6. 2009
    ..Thus, liver disease is currently the second leading cause of death in HIV-infected persons in Europe...
  30. doi request reprint Prevaccination genomic diversity of human papillomavirus genotype 6 (HPV 6)
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloska 4, 1105 Ljubljana, Slovenia
    Virology 391:274-83. 2009
    ..The presence of serious HPV 6 genome sequence errors was confirmed and novel sequence errors were identified in sequence repositories...
  31. doi request reprint Detection and typing of low-risk human papillomavirus genotypes HPV 6, HPV 11, HPV 42, HPV 43 and HPV 44 by polymerase chain reaction and restriction fragment length polymorphism
    Polona J Maver
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloska 4, 1105 Ljubljana, Slovenia
    J Virol Methods 169:215-8. 2010
    ..The novel assay is simple and robust, does not require any sophisticated equipment and can be of great value for epidemiological studies, particularly in settings in which financial resources are limited...
  32. ncbi request reprint HIV-1 subtype B epidemic and transmission patterns in Slovenia
    Dunja Z Babic
    Slovenian HIV AIDS Reference Laboratory, Institute of Microbiology and Immunology, Faculty of Medicine, Ljubljana, Slovenia
    Coll Antropol 30:25-31. 2006
    ..Recent subtype B HIV-1 infections are the important driving force of current HIV-1 epidemic in Slovenia...
  33. ncbi request reprint Twenty-four mini-pool HCV RNA screening outside a blood transfusion setting: results of a 2-year prospective study
    Katja Seme
    Institute of Microbiology and Immunology, Medical Faculty of Ljubljana, Zaloska 4, 1000 Ljubljana, Slovenia
    J Virol Methods 140:218-21. 2007
    ..It was shown that screening for HCV infection using the 24 mini-pool HCV RNA screening strategy can also be both useful and cost effective outside a blood transfusion setting...
  34. ncbi request reprint Human papillomaviruses (HPV) in tissue specimens of oral squamous cell papillomas and normal oral mucosa
    Andrej A Kansky
    Department of Maxillofacial and Oral Surgery, University Medical Center, Zaloska 2, 1000 Ljubljana, Slovenia
    Anticancer Res 26:3197-201. 2006
    ..The etiology of oral squamous cell papillomas (OSCP) is still unresolved...
  35. ncbi request reprint Comparative evaluation of the Abbott RealTime High Risk HPV test and INNO-LiPA HPV Genotyping Extra test for detecting and identifying human papillomaviruses in archival tissue specimens of head and neck cancers
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloška cesta 4, SI 1105 Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 21:73-5. 2012
    ....
  36. pmc Short communication: prevalence of HIV type 1 transmitted drug resistance in Slovenia: 2005-2010
    Maja M Lunar
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    AIDS Res Hum Retroviruses 29:343-9. 2013
    ..Although the prevalence of TDR in Slovenia is still below the European average, active surveillance should be continued, especially among MSM, the most vulnerable population for HIV-1 infection in this part of Europe...
  37. doi request reprint Identical human papillomavirus (HPV) genomic variants persist in recurrent respiratory papillomatosis for up to 22 years
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, University of Ljubljana, Ljubljana, Slovenia
    J Infect Dis 207:583-7. 2013
    ..Frequent recurrence of laryngeal papillomas is a consequence of long-term persistence of the identical initial HPV genomic variant...
  38. ncbi request reprint Genomic distribution of beta papillomaviruses in single eyebrow hair samples and pools of eyebrow hair samples
    Kristina Fujs Komlos
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 20:155-60. 2011
    ..Our results suggest that beta-HPVs are unevenly distributed over the eyebrows and even pools made of several hairs do not necessarily provide information on the whole spectrum of HPV genotypes present in eyebrows...
  39. doi request reprint Pre-vaccination prevalence and distribution of high-risk human papillomavirus (HPV) types in Slovenian women: a cervical cancer screening based study
    Veronika Ucakar
    National Institute of Public Health, Trubarjeva 2, 1000 Ljubljana, Slovenia
    Vaccine 30:116-20. 2012
    ..Our results provide baseline data for monitoring the impact of Slovenian HPV vaccination program and development of future cervical cancer screening strategies in cohorts eligible for free HPV vaccination...
  40. doi request reprint Prevaccination genomic diversity of human papillomavirus genotype 11: a study on 63 clinical isolates and 10 full-length genome sequences
    Polona J Maver
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Med Virol 83:461-70. 2011
    ..Within the ethnogeographically closed cohort investigated in this study, HPV 11 was shown to be less polymorphic in comparison to the majority of HPV genotypes studied to date...
  41. ncbi request reprint Genomic diversity of human papillomavirus genotype 53 in an ethnogeographically closed cohort of white European women
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Ljubljana, Slovenia
    J Med Virol 79:431-8. 2007
    ..In rare cases, infection with multiple HPV-53 genomic variants is possible. Taking into account the results of this and previous studies, at least 26 different HPV-53 genomic variants exist today...
  42. ncbi request reprint Distribution of human papillomavirus genotypes in plucked eyebrow hairs from Slovenian males with genital warts
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Medical Faculty, Zaloska 4, 1105 Ljubljana, Slovenia
    Infect Genet Evol 5:255-9. 2005
    ....
  43. doi request reprint Twenty-four mini-pool HCV RNA screening in a routine clinical virology laboratory setting: a six-year prospective study
    Katja Seme
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Virol Methods 171:303-5. 2011
    ....
  44. ncbi request reprint Prevalence, genotype distribution, and risk factors for hepatitis C infection among HIV-infected individuals in Slovenia: a 1986-2013 update
    Mateja Skamperle
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 23:25-6. 2014
    ..Two previous Slovenian nationwide studies published in 2002 and 2009 showed a very low prevalence of hepatitis C virus (HCV) infection among Slovenian HIV-infected individuals (14.5% and 10.7%, respectively)...
  45. doi request reprint Distribution of human papillomavirus genotypes in women with cervical cancer in Slovenia
    Nina Jancar
    Department of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana, Slovenia
    Eur J Obstet Gynecol Reprod Biol 145:184-8. 2009
    ....
  46. ncbi request reprint Molecular epidemiology of HIV-1 subtypes based on analysis of pol sequences in Slovenia, 1996-2005
    Dunja Z Babic
    Institute of Microbiology and Immunology, Medical Faculty, Ljubljana, Slovenia
    J Med Virol 78:997-1002. 2006
    ..In contrast to Western European countries, a significant increase (P = 0.015) in the proportion of men who have sex with men was observed recently among newly diagnosed HIV-1 infected patients in Slovenia...
  47. ncbi request reprint Comparative evaluation of three commercial assays for quantitative measurement of hepatitis B virus DNA in serum samples
    Irena J Marin
    Institute of Microbiology and Immunology, Medical Faculty, Zaloska 4, 1105 Ljubljana, Slovenia
    Hepatogastroenterology 49:1390-4. 2002
    ..Quantitative determination of HBV DNA in serum samples is indispensable for predicting disease progression and for monitoring the antiviral treatment in patients with chronic HBV infection...
  48. ncbi request reprint Telomerase catalytic subunit gene expression does not influence survival of patients with squamous cell carcinoma of the larynx and hypopharynx: a case-control study
    Bostjan Luzar
    Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Laryngol Otol 119:917-21. 2005
    ....
  49. ncbi request reprint Resolving repeatedly borderline results of Hybrid Capture 2 HPV DNA Test using polymerase chain reaction and genotyping
    Katja Seme
    Institute of Microbiology and Immunology, Medical Faculty of Ljubljana, Zaloska 4, 1000 Ljubljana, Slovenia
    J Virol Methods 134:252-6. 2006
    ....
  50. ncbi request reprint Prevalence of antiretroviral drug resistance mutations and HIV-1 non-B subtypes in newly diagnosed drug-naïve patients in Slovenia, 2000-2004
    Dunja Z Babic
    Institute of Microbiology and Immunology, Medical Faculty, Zaloska 4, 1000 Ljubljana, Slovenia
    Virus Res 118:156-63. 2006
    ..5%). In conclusion, testing the vast majority of all newly diagnosed HIV-1 patients in the last 5 years in Slovenia uncovered a relatively high prevalence of non-B subtypes and a low prevalence of transmitted drug resistance...
  51. ncbi request reprint Human papillomavirus (HPV) prevalence and HPV type distribution in cervical, vulvar, and anal cancers in central and eastern Europe
    Mateja Skamperle
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloska cesta 4, SI 1105 Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 22:1-5. 2013
    ..High-risk human papillomaviruses (HPV) play the leading etiological role in the development of cervical, anal, and vaginal cancers and a substantial proportion of penile, vulvar, and oropharyngeal (tonsillar) cancers...
  52. ncbi request reprint Distribution of HPV genotypes in Slovenian patients with anal carcinoma: preliminary results
    Kristina Fujs Komlos
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 20:141-3. 2011
    ..Prophylactic HPV vaccination with currently available vaccines could potentially prevent the great majority of anal cancers in Slovenia...
  53. doi request reprint Rapid detection and typing of Molluscum contagiosum virus by FRET-based real-time PCR
    Lea Hosnjak
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Virol Methods 187:431-4. 2013
    ..The novel assay is simple, robust and easy to perform, and may be of great value for clinical and epidemiological studies of MCV infections and related conditions...
  54. ncbi request reprint Telomerase catalytic subunit in laryngeal carcinogenesis--an immunohistochemical study
    Bostjan Luzar
    Institute of Pathology, Medical Faculty University of Ljubljana, Ljubljana, Slovenia
    Mod Pathol 18:406-11. 2005
    ....
  55. ncbi request reprint False-positive result of a confirmatory human immunodeficiency virus line immuno assay in an apparently healthy individual--a case report
    Katja Seme
    Slovenian HIV AIDS Reference Laboratory, Institute of Microbiology and Immunology, Faculty of Medicine, Ljubljana, Slovenia
    Coll Antropol 30:43-6. 2006
    ....
  56. ncbi request reprint Clinical features and virologic characteristics of primary and early HIV-1 infection in Slovenian patients
    Mateja Pirs
    Slovenian HIV AIDS Reference Laboratory, Institute of Microbiology and Immunology, Faculty of Medicine, Ljubljana, Slovenia
    Coll Antropol 30:47-52. 2006
    ....
  57. ncbi request reprint Pre-vaccination seroprevalence of 15 human papillomavirus (HPV) types among women in the population-based Slovenian cervical screening program
    Veronika Ucakar
    Department of Communicable Diseases and Environmental Threats, National Institute of Public Health, Trubarjeva 2, 1000 Ljubljana, Slovenia
    Vaccine 31:4935-9. 2013
    ..To estimate seroprevalence of 11 high-risk (hr) HPV types and four low-risk (lr) HPV types among 20-64 years old Slovenian women participating in the population-based cervical cancer screening program...
  58. ncbi request reprint Detection and differentiation of human papillomavirus genotypes HPV-6 and HPV-11 by FRET-based real-time PCR
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Faculty of Medicine, Ljubljana, Slovenia
    J Virol Methods 153:245-9. 2008
    ....
  59. doi request reprint Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck
    Nika Kojc
    Institute of Pathology, Faculty of Medicine, University of Ljubljana, Korytkova 2, 1000, Ljubljana, Slovenia
    Virchows Arch 454:549-55. 2009
    ..Our finding of upregulation of all four tested transcription factors supports the hypothesis that EMT plays an important role in the pathogenesis of SpCC of the head and neck...
  60. ncbi request reprint Prevalence of HPV 16 genomic variant carrying a 63 bp duplicated sequence within the E1 gene in Slovenian women
    Zeljka Bogovac
    National Forensic Laboratory, Ministry of the Interior, Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 20:135-9. 2011
    ..No statistically significant differences in the prevalence of HPV-16 E1 insert genomic variant in women presenting with normal cytology and those with the different stages of HPV-16-induced disease were found...
  61. doi request reprint Pre-vaccination genomic diversity of human papillomavirus genotype 6 (HPV 6): a comparative analysis of 21 full-length genome sequences
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Infect Genet Evol 11:1805-10. 2011
    ..However, this diversification trend was more evident in non-coding regions LCR and NNCR3 and early viral genes E4, E5a and E5b...
  62. doi request reprint Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck--hallmark of epithelial-mesenchymal transition
    Nina Zidar
    Institute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia
    Hum Pathol 42:482-8. 2011
    ..The result is not only an altered expression of classic cadherins in adherens junctions but also a complete loss of desmosomal cadherins...
  63. doi request reprint Current review on squamous intraepithelial lesions of the larynx
    Nina Gale
    Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Histopathology 54:639-56. 2009
    ..Despite extensive research into these genetic changes in laryngeal carcinogenesis, reliable genetic markers with diagnostic and prognostic value are still lacking...
  64. doi request reprint Universal ProbeLibrary based real-time PCR assay for detection and confirmation of human papillomavirus genotype 52 infections
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloska 4, 1105 Ljubljana, Slovenia
    J Virol Methods 163:492-4. 2010
    ..8%) were identified as also containing HPV 52 using RT-PCR. All 16 Linear Array "true HPV 52-positive" samples were confirmed to contain HPV 52 DNA in RT-PCR testing...
  65. ncbi request reprint Low prevalence of hepatitis C virus infection among human immunodeficiency virus type 1-infected individuals from Slovenia and Croatia
    K Seme
    Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Slovenia
    Acta Virol 46:91-4. 2002
    ....
  66. ncbi request reprint Verrucous carcinoma of the head and neck - not a human papillomavirus-related tumour?
    Katarina Odar
    Faculty of Medicine, Institute of Pathology, University of Ljubljana, Ljubljana, Slovenia
    J Cell Mol Med 18:635-45. 2014
    ..PV DNA in a subset of VC and normal tissue might reflect incidental colonization, but its potential biological significance needs further investigation. ..
  67. ncbi request reprint Current status of human papillomavirus vaccination implementation in central and eastern Europe
    Katja Seme
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 22:21-5. 2013
    ..The key reasons for lack of implementation of HPV vaccination into the national immunization program are the high vaccine cost and negative public perception. Vaccination of males is not recommended in any country in the region...
  68. ncbi request reprint Genetic diversity of HPV-6 in concurrent multiple anogenital warts
    Kristina Fujs Komlos
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloška cesta 4, SI 1105 Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 22:31-3. 2013
    ..However, it is not clear whether the occurrence of multiple AGW in a particular patient is a consequence of infection with single or multiple HPV genomic variants of a given HPV genotype...
  69. doi request reprint Genomic variants of human papillomavirus genotypes 16, 18, and 33 in women with cervical cancer in Slovenia
    Eda Vrtacnik Bokal
    Department of Obstetrics and Gynecology, University Medical Centre Ljubljana Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    J Obstet Gynaecol Res 36:1204-13. 2010
    ..Our aim was to analyze genomic variants of the three most common human papillomavirus (HPV) genotypes found in Slovenian women with cervical cancer (CC)...
  70. doi request reprint Hepatitis E virus in domestic pigs and surface waters in Slovenia: prevalence and molecular characterization of a novel genotype 3 lineage
    Andrej Steyer
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloska 4, SI 1000 Ljubljana, Slovenia
    Infect Genet Evol 11:1732-7. 2011
    ..One human HEV strain belonged to genotype 1 and two to genotype 3 but did not match the new genotype 3 lineage detected in Slovenian pig herds...
  71. ncbi request reprint Unlinked anonymous monitoring of human immunodeficiency virus prevalence in high- and low-risk groups in Slovenia, 1993-2002
    Irena Klavs
    Institute of Public Health of the Republic of Slovenia, Trubarjeva 2, 1000 Ljubljana, Slovenia
    Croat Med J 44:545-9. 2003
    ....
  72. ncbi request reprint The role of core antigen detection in management of hepatitis C: a critical review
    Katja Seme
    Medical Faculty, Institute of Microbiology and Immunology, Zaloska 4, 1000 Ljubljana, Slovenia
    J Clin Virol 32:92-101. 2005
    ....
  73. ncbi request reprint Detection of hepatitis C virus RNA from gingival crevicular fluid and its relation to virus presence in saliva
    M Maticic
    Department of Infectious Diseases, University Medical Centre, Ljubljana, Slovenia
    J Periodontol 72:11-6. 2001
    ..The results provide a biologic basis for further investigation of the role of HCV in the pathogenesis of periodontal disease...
  74. doi request reprint Lack of evidence for hepatitis C virus infection in association with lichen planus
    Larisa Stojanovic
    Institute of Anatomy, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Int J Dermatol 47:1250-6. 2008
    ..The Slovenian population is rather homogenous with specific geographic and epidemiological characteristics. Lack of data or contradictory results from neighboring countries urged the need for a case-controlled study in our LP patients...
  75. doi request reprint Comparison of the Abbott RealTime High Risk HPV test and INNO-LiPA HPV Genotyping Extra test for the detection of human papillomaviruses in formalin-fixed, paraffin-embedded cervical cancer specimens
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloska 4, 1105 Ljubljana, Slovenia
    J Virol Methods 175:117-9. 2011
    ..The tissue preparation protocol was shown to be sample-to-sample contamination safe...
  76. ncbi request reprint Blood-stained letter received by HIV/AIDS reference laboratory in 1993--a historical case report
    Polona J Maver
    Slovenian HIV AIDS Reference Laboratory, Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Coll Antropol 30:39-42. 2006
    ..Since no anti HIV-1/2 antibodies were detected in his serum sample, our initial HIV negative findings based on PCR testing of blood spots were confirmed...
  77. ncbi request reprint Does end-stage kidney failure influence hepatitis C progression in hemodialysis patients?
    Bostjan Luzar
    Institute of Pathology, Medical Faculty University of Ljubljana, Slovenia
    Hepatogastroenterology 50:157-60. 2003
    ..The influence of end-stage kidney failure on the progression of liver disease in patients infected with hepatitis C virus and treated with hemodialysis is still controversial...
  78. ncbi request reprint Molecular evidence for nosocomial spread of two different hepatitis C virus strains in one hemodialysis unit
    K Seme
    Institute of Microbiology and Immunology, Medical Faculty, Ljubljana, Slovenia
    Nephron 77:273-8. 1997
    ..The study confirmed that implementation of rigorous hygienic routines and introduction of separate rooms and machines for HCV-infected patients are important measures for effective control of HCV infection in a hemodialysis environment...
  79. ncbi request reprint Prevalence of hepatitis G virus infection in Slovenian hemodialysis patients as determined by the detection of viral genome and E2 antibodies
    K Seme
    Institute of Microbiology and Immunology, Medical Faculty of Ljubljana, Slovenia
    Nephron 79:426-9. 1998
    ..Therefore, when assessing the prevalence of HGV infection in hemodialysis patients, detection of both antibody and nucleic acid is requisite...
  80. pmc Comparative evaluation of first- and second-generation digene hybrid capture assays for detection of human papillomaviruses associated with high or intermediate risk for cervical cancer
    M Poljak
    Institute of Microbiology and Immunology, Medical Faculty, Ljubljana, Slovenia
    J Clin Microbiol 37:796-7. 1999
    ..The enhanced sensitivity of the second-generation assay is mainly a result of the reformulation of hybridization reagents and, to a lesser extent, a result of the addition of new HPV probes...
  81. ncbi request reprint The Ljubljana classification: a practical strategy for the diagnosis of laryngeal precancerous lesions
    N Gale
    Institute of Pathology, Faculty of Medicine, University of Ljubljana, Slovenia
    Adv Anat Pathol 7:240-51. 2000
    ..For diagnostically difficult cases, supplementary techniques such as those using morphometry, immunohistochemical and molecular biology are advised to improve the accuracy of diagnosis and predictions of their biological behavior...
  82. ncbi request reprint Rapid extraction of DNA from archival clinical specimens: our experiences
    M Poljak
    Institute of Microbiology and Immunology, Medical Faculty, Ljubljana, Slovenia
    Pflugers Arch 439:R42-4. 2000
    ..Our results demonstrate that rapid DNA extraction methods have comparable DNA extraction efficiencies with standard DNA isolation protocols on archival clinical specimens with the exception of Giemsa-stained smears...
  83. pmc Evaluation of the automated COBAS AMPLICOR hepatitis C virus PCR system
    M Poljak
    Institute of Microbiology and Immunology, Medical Faculty, Ljubljana, Slovenia
    J Clin Microbiol 35:2983-4. 1997
    ..The automated HCV COBAS AMPLICOR system provides the clinical microbiology laboratory with a specific and sensitive PCR method for rapid and reliable detection of HCV RNA...
  84. ncbi request reprint Chromosomes 7,17 polysomies and overexpression of epidermal growth factor receptor and p53 protein in epithelial hyperplastic laryngeal lesions
    N Gale
    Institute of Pathology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia
    Oncology 58:117-25. 2000
    ..The specific aim was to compare the results and prognostic significance between the two types of EHLL: isolated, mainly atypical hyperplasia or risky epithelium, and EHLL associated with squamous cell carcinoma (SCC)...
  85. ncbi request reprint Quantitative measurement of telomerase catalytic subunit (hTERT) mRNA in laryngeal squamous cell carcinomas
    B Luzar
    Institute of Pathology, Medical Faculty University of Ljubljana, Slovenia
    Anticancer Res 21:4011-5. 2001
    ..However, the greater quantity of h TERT mRNA in LSCCs is the result of telomerase reactivation in the process of laryngeal carcinogenesis...
  86. ncbi request reprint Seroprevalence of human T cell leukaemia/lymphoma virus type I (HTLV-I) in pregnant women, patients attending venereological outpatient services and intravenous drug users from Slovenia
    M Poljak
    Slovenian AIDS Reference Center, Institute of Microbiology and Immunology, Medical Faculty, Ljubljana
    Folia Biol (Praha) 44:23-5. 1998
    ..The prevalence of antibodies to HTLV-I in the Slovenian population might be somewhere between one in 10,000 (0.01%) and one in 15,000 (0.0066%), which is similar or even higher to prevalence rates in other European countries...
  87. ncbi request reprint Genetic analysis of wild-type Dobrava hantavirus in Slovenia: co-existence of two distinct genetic lineages within the same natural focus
    T Avsic-Zupanc
    Institute of Microbiology and Immunology, Medical Faculty of Ljubljana, Zaloska 4, 1000 Ljubljana, Slovenia
    J Gen Virol 81:1747-55. 2000
    ..agrarius from Russia, Estonia and Slovakia. These findings suggest that the DOB variants carried by the two species of APODEMUS: in Europerepresent two distinct genetic lineages...
  88. ncbi request reprint Human papillomavirus DNA in oral squamous cell carcinomas and normal oral mucosa
    A A Kansky
    Department of Maxillofacial and Oral Surgery, University Medical Center, Ljubljana, Slovenia
    Acta Virol 47:11-6. 2003
    ....
  89. ncbi request reprint Langerhans cells in human papillomaviruses types 6/11 associated laryngeal papillomas
    D Ferluga
    Institute of Pathology, Medical Faculty, University of Ljubljana, Slovenia
    Acta Otolaryngol Suppl 527:87-91. 1997
    ....
  90. ncbi request reprint Simple one-tube reverse transcription-polymerase chain reaction protocol containing anticontamination procedure for detection of GB virus C/hepatitis G virus RNA
    M Poljak
    Institute of Microbiology and Immunology, Medical Faculty of Ljubljana, Slovenia
    J Virol Methods 71:1-6. 1998
    ..The novel method provides the potential for automated, simple, rapid and accurate routine detection of GBV-C/HGV RNA in diagnostic virological laboratories...
  91. ncbi request reprint Particle agglutination test "Serodia HIV-1/2" as a novel anti-HIV-1/2 screening test: comparative study on 3311 serum samples
    M Poljak
    Slovenian AIDS Reference Center, Institute of Microbiology and Immunology, Medical Faculty of Ljubljana, Slovenia
    Folia Biol (Praha) 43:171-3. 1997
    ..97%, respectively. We have concluded that Serodia HIV-1/2 test is highly specific and sensitive for detection of anti-HIV-1/2 antibodies, suitable for small blood banks and for epidemiological surveys...
  92. ncbi request reprint Comparative evaluation of four genotyping methods for hepatitis C virus
    K Seme
    Institute of Microbiology and Immunology, Medical Faculty, Ljubljana, Slovenia
    Folia Biol (Praha) 43:219-24. 1997
    ..The specificity of genotyping methods, which are based on the 5' NCR or the core region, was occasionally hampered, due to a lack or excess of sequence variation in their respective target regions...
  93. ncbi request reprint Human telomerase catalytic subunit gene re-expression is an early event in oral carcinogenesis
    B Luzar
    Institute of Microbiology and Immunology, University of Ljubljana, Slovenia
    Histopathology 45:13-9. 2004
    ....
  94. ncbi request reprint Human papillomavirus infection and expression of p53 and c-erbB-2 protein in laryngeal papillomas
    B Luzar
    Institute of Pathology, Medical Faculty, University of Ljubljana, Slovenia
    Acta Otolaryngol Suppl 527:120-4. 1997
    ..This may represent either an alteration in the processing stability of the c-erbB-2 mRNA, gene amplification, or even an artefact...
  95. ncbi request reprint Acute fatty liver of pregnancy -- an underlying condition for herpes simplex type 2 fulminant hepatitis necessitating liver transplantation
    B Luzar
    Institute of Pathology, Medical Faculty, Ljubljana, Slovenia
    Z Gastroenterol 43:451-4. 2005
    ..We believe that early histopathological diagnosis, followed by specific antiviral treatment and liver transplantation in selected patients may improve the clinical outcome of otherwise almost uniformly fatal HSV hepatitis...
  96. pmc Expression of human telomerase catalytic protein in gallbladder carcinogenesis
    B Luzar
    Institute of Pathology, Medical Faculty, University of Ljubljana, Korytkova 2, 1000 Ljubljana, Slovenia
    J Clin Pathol 58:820-5. 2005
    ..Telomerase catalytic subunit (hTERT) gene re-expression is a rate limiting step for the activity of telomerase, a key enzyme implicated in cellular immortalisation and transformation...
  97. ncbi request reprint Epidermal growth factor receptor, c-erbB-2 and p53 overexpressions in epithelial hyperplastic lesions of the larynx
    N Gale
    Institute of Pathology, Medical Faculty, University of Ljubljana, Slovenia
    Acta Otolaryngol Suppl 527:105-10. 1997
    ....
  98. ncbi request reprint Influenza vaccination of human immunodeficiency virus 1-infected patients receiving antiretroviral therapy
    S Banic
    Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Slovenia
    Acta Virol 45:39-44. 2001
    ..We propose that HIV-positive patients receiving HAART should be subjected to annual influenza vaccination...