Mitja Lainscak

..We aimed to evaluate the relation between SRH and adverse events during titration of beta-blockers in elderly patients with heart failure...

..This study compared effects of bisoprolol and carvedilol in patients with both conditions...

..Lastly, we anticipate the potential of biomarkers in a variety of chronic diseases with similar pathophysiology...

..Beta-blockers are well established for treatment of chronic heart failure (CHF). However, the extent of implementation of trial results and guidelines in daily practice remains limited, and information regarding how patients feel is scarce...

..There are limited data on recall and implementation of lifestyle advice in patients with heart failure (HF)...

..In this paper, we review data on incidence, prognostic importance and treatment modalities of atrial fibrillation in patients with cancer, chronic obstructive pulmonary disease, and chronic kidney disease...

..Among the recognized approaches, exogenous oral amino acid supplementation appears very promising. Further research efforts are needed and they are ongoing...

..Ultimately, cachexia may develop in 10-15% of patients, who usually perish soon after. We currently have neither a globally accepted definition of cachexia nor any treatment to prevent or treat cachexia...

..Finally, we speculate about the potential of sharing the biomarkers over a variety of chronic diseases with similar pathophysiology...

..There is limited evidence that the use of prognostic markers to make treatment decisions improves the outcome in CHF. Many studies still need to be done to this end...

..Our aim was to determine the prevalence and clinical impact of COPD among patients hospitalized for heart failure in a community hospital serving a population of 125,000 people...

..The authors review some of those biomarkers and speculate on the possible roles of combining two or more of them...

..The MARVEL-1 trial raises further concerns about the safety of myoblast transplantation in ischaemic HF...

..In addition, a substantial proportion of those who recall the advice follow it incompletely. Younger age and prescription of appropriate pharmacologic treatment are associated with higher rates of recall and implementation...

..Cachexia is an independent risk factor for mortality in chronic heart failure (CHF). Beta blockers can reduce body energy expenditure and improve efficiency of substrate utilization...

..boydii infection in a patient with microscopic polyangiitis. Favorable outcome related to the treatment with voriconazole adds to the growing body of evidence supporting the use of this particular agent in P. boydii infections...

..We aimed to compare the outcome, pharmacological therapy, and quality of life in unselected heart failure patients from a community hospital area who were managed either in the heart failure clinic or who received the usual care...

..Hospitalizations and symptoms of heart failure negatively influence patients' quality of life. In Slovenia there is a scarcity of non-pharmacological management and quality of life data in heart failure patients...

..Only a limited number of validated tools are available to assess their knowledge. The aim of the study was to test our 10-item Patient knowledge questionnaire...

..Several studies have shown improvement of prognosis in patients managed in heart failure (HF) clinics. However, the value of the individual management components is not well established...

..There is a scarcity of data on changes in the management of patients hospitalized with heart failure...

..This may reflect a lack of adequate organisation of care or co-morbidity contra-indicating therapy...

..Endocarditis due to Abiotrophia sp. is rare and often associated with negative blood cultures. The rates of treatment failure, infection relapse and mortality are higher than in endocarditis caused by other viridans streptococci...

..Acute heart failure is associated with a poor prognosis. It is important to identify patients at increased risk of adverse events. The presence of anaemia could help in this regard...

..The aim of this study was therefore to compare the tolerability and clinical effects of two proven beta-blockers in elderly patients with heart failure...

..Beta-blockers have further not been adequately tested in patients with diastolic CHF, which is particularly common in elderly patients. Finally, comparative data on the use of different beta-blockers in patients with CHF is scarce...

..Retrospective and epidemiological data for their beneficial effect in chronic obstructive pulmonary disease begin to accumulate and new fields (e.g. cancer and stroke) could be pending in the future...

..Other drug classes of interest comprise angiotensin-converting enzyme inhibitors, beta-blockers, anabolic steroids, beta-adrenergic agonists, anti-inflammatory substances, statins, thalidomide, proteasome inhibitors, and pentoxifylline...

..Our results set the stage for future research to determine specific benefit of transcutaneous electrical muscle stimulation, either alone or in combination with nutritional support and pharmacological therapy...

..We have conceived this analysis to study the associations between MNA questionnaire, body composition, and rehospitalisations in patients with COPD...

..Their value and discriminatory power in comparison to dynamic range assessment of Si by minimal modelling are not well established...

..This review will focus on recent developments and potential future candidates of pharmacological CHF therapy...

..We aimed to test the ancillary metabolic effect of irbesartan on insulin sensitivity in patients with CHF...

..This article summarizes existing data on ANP and related peptides in cardiovascular and other disorders, and outlines the potential clinical usefulness of these markers...

..In addition to these acute phase reactants, several adhesion molecules, and lipopolysaccharide-signaling pathways are discussed...

..This retrospective study aimed to assess the implementation of COPD guidelines and potential association with long-term mortality in patients with COPD...

..We aimed to investigate associations between N-terminal pro B-type natriuretic peptide (NT-proBNP) and troponin T during hospitalisation with 6-month outcome...

..Impaired glucose metabolism ranges from insulin resistance to overt diabetes mellitus, which is a frequent finding and is associated with worse outcome...

..On the other hand, there have been failures such as vasoactive intestinal peptide, statins, and escitalopram. Several new drugs and gene therapy are under investigation, thus significant advances are anticipated...

..There is little information on the preventive use of low-molecular-weight heparin (LMWH) in hospitalized patients with pneumonia...

..Intensive multidisciplinary approach can improve management of the patients with heart failure...

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..Routine spirometry and echocardiography in HF and COPD patients, respectively, is therefore warranted to improve current clinical practice...

..It also defines avenues of research to optimize self-care strategies in a number of key areas to derive further benefits...

..Nurse specialist has a decisive role in implementation of evidence based management which can have effects beyond patient care...

..The test was integrated to exercise related health promotion programme, and widely available information technologies will be used for data management...

..We discuss this study in detail. Further studies are needed to substantiate this link and to generally explore the value of testosterone therapy in CHF patients...

..As, in many patients, drug co-treatment cannot be avoided, we investigated the effect of co-treatment with carbamazepine, amiodarone and statins on warfarin metabolism and maintenance dose...