Research Topics
Species | Adela PenesovaSummaryAffiliation: Slovak Academy of Sciences Country: Slovakia Publications
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Detail Information
Publications
Chronic inflammation and low-dose glucocorticoid effects on glucose metabolism in premenopausal females with rheumatoid arthritis free of conventional metabolic risk factorsA Penesova
Laboratory of Human Endocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovak Republic
Physiol Res 62:75-83. 2013..Increased cardiovascular mortality and morbidity is probably due to a direct effect of systemic inflammation on myocardium and/or blood vessels...
The role of endocrine mechanisms in ventilator-associated lung injury in critically ill patientsA Penesova
Laboratory of Human Endocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Endocr Regul 46:161-6. 2012..The present review is aimed to describe some of the pathophysiologic aspects of VALI providing a basis for novel therapeutic strategies in the critically ill patients...
Short-term isocaloric manipulation of carbohydrate intake: effect on subsequent ad libitum energy intakeAdela Penesova
Department of Health and Human Services, Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 4212N 16th Street, Phoenix, AZ 85016, USA
Eur J Nutr 50:455-63. 2011..Isocaloric manipulation of carbohydrate or fat intake could alter subsequent ad libitum food intake...
Effect of paternal diabetes on pre-diabetic phenotypes in adult offspringAdela Penesova
Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Phoenix, Arizona, USA
Diabetes Care 33:1823-8. 2010..We aimed to examine a metabolic phenotype in three different groups of offspring to see distinct paternal versus maternal effects...
The role of norepinephrine and insulin resistance in an early stage of hypertensionAdela Penesova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Ann N Y Acad Sci 1148:490-4. 2008....
Insertion/deletion polymorphism on ACE gene is associated with endothelial dysfunction in young patients with hypertensionA Penesova
Institute of Experimental Endocrinology Slovak Academy of Sciences, Bratislava, Slovakia
Horm Metab Res 38:592-7. 2006....
Comparison of insulin sensitivity indices calculated from standard 3-sampled and frequently sampled oral glucose tolerance testAdela Penesova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, 833 06 Bratislava, Slovakia
Endocr Regul 38:167-71. 2004....
Attenuated insulin response and normal insulin sensitivity in lean patients with ankylosing spondylitisA Penesova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 833 06 Bratislava, Slovakia
Int J Clin Pharmacol Res 25:107-14. 2005..Our results indicate that elevated IL-6 levels may play a pathophysiological role in attenuating beta-cell responsiveness, which may explain the association between elevated IL-6 levels and increased risk for type 2 diabetes...
Sympathetic nervous system response to orthostatic stress in female patients with rheumatoid arthritisMiroslav Vlcek
Institute of Experimental Endocrinology, SAS, Bratislava, Slovakia
Ann N Y Acad Sci 1148:556-61. 2008..A subtle tendency to decreased adrenomedullary reactivity but no evidence for abnormal sympathetic responses to orthostasis was found in RA females...
Autonomic nervous system function in rheumatoid arthritisMiroslav Vlcek
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Cell Mol Neurobiol 32:897-901. 2012..The RA and control groups did not differ in heart rate and HRV parameters. This study showed normal reactivity of the sympathoneural and the adrenomedullary systems during orthostatic challenge in RA patients younger than 40 years...
Adipokine protein expression pattern in growth hormone deficiency predisposes to the increased fat cell size and the whole body metabolic derangementsJozef Ukropec
Diabetes Laboratory, Institute of Experimental Endocrinology, Centre of Excellence acknowledged by European Commission, Slovak Academy of Sciences, Vlarska 3, Bratislava, Slovak Republic
J Clin Endocrinol Metab 93:2255-62. 2008....
Adrenocortical response to low-dose ACTH test in female patients with rheumatoid arthritisZofia Radikova
Institute of Experimental Endocrinology SAS, Bratislava, Slovakia
Ann N Y Acad Sci 1148:562-6. 2008..001), whereas there was no change in the control group. The present results show decreased secretion of cortisol and DHEA in RA patients in response to ACTH, suggesting a subtle HPA hypofunction at the adrenocortical level...
Heart rate variability and catecholamines during hypoglycemia and orthostasisMiroslav Vlcek
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Auton Neurosci 143:53-7. 2008..In conclusion, the present study shows an increase in low frequency component of HRV in response to orthostasis or hypoglycemia with significant, however inconsistent association to changes in plasma catecholamines...
Cardiovascular diseases and molecular variants of the renin-angiotensin system components in Slovak populationD Jurkovicova
Institute of Molecular Physiology and Genetics, Centre of Excellence for Cardiovascular Research of Slovak Academy of Sciences, Bratislava, Slovakia
Gen Physiol Biophys 26:27-32. 2007..Our results suggest that in Slovak population, D alelle and M235T variant represent a risk factor for several cardiovascular diseases and these polymorphisms might have a cumulative effect on development of cardiovascular diseases...
Comparison of salivary cortisol and calculated free plasma cortisol during low-dose ACTH test in healthy subjectsJana Kerlik
Laboratory of Human Endocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia
Clin Biochem 43:764-7. 2010..To compare free plasma cortisol (FPC) with salivary and calculated cortisol...
Protein array reveals differentially expressed proteins in subcutaneous adipose tissue in obesityMartina Skopková
Institute of Experimental Endocrinology, EU Centre of Excellence, Slovak Academy of Sciences, Vlarska 3, SK 83306 Bratislava, Slovak Republic
Obesity (Silver Spring) 15:2396-406. 2007..Nevertheless, new factors that play an important role in these processes are still emerging. Therefore, we screened the level of 120 different proteins in biopsies of subcutaneous adipose tissue (ScAT) of lean and obese subjects...
Effects of endogenous and exogenous hypercortisolemia on low-dose adrenocorticotropin test outcome in humansJ Kerlik
Laboratory of Human Endocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 833 06, Bratislava, Slovakia
J Endocrinol Invest 32:677-81. 2009..The results of low-dose ACTH testing may be impaired during endogenous or exogenous hypercortisolemia in various clinical situations...
Impaired insulin secretion and uptake in patients with diffuse idiopathic skeletal hyperostosisM Eckertova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Endocr Regul 43:149-55. 2009....
Decreased pituitary response to insulin-induced hypoglycaemia in young lean male patients with essential hypertensionZ Radikova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
J Hum Hypertens 20:510-6. 2006..Increased norepinephrine levels and a decreased pituitary response to metabolic stress stimuli may represent another manifestation of chronically increased sympathetic tone in early hypertension...
Body position and the neuroendocrine response to insulin-induced hypoglycemia in healthy subjectsZ Radikova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Arch Physiol Biochem 111:399-405. 2003..In conclusion, we suggest that body position and accompanying plasma volume changes do not appear to affect neuroendocrine and counterregulatory responses to moderate, short duration hypoglycemia in healthy subjects...
Does orthostatic stress influence the neuroendocrine response to subsequent hypoglycemia in humans?Z Radikova
MD, PhD, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 833 06 Bratislava, Slovakia
Ann N Y Acad Sci 1018:576-81. 2004..In the case of ACTH, the first stress stimulus is consequential for the subsequent response of this hormone, probably due to short-loop negative feedback effects...
Computer controlled sequential simulation method: reconsidering evaluation of measurements from frequently sampled intravenous glucose tolerance testLadislav Dedik
Faculty of Mechanical Engineering, Institute of Automation, Measurement and Applied Informatics, Slovak University of Technology, Bratislava, Slovak Republic
Comput Methods Programs Biomed 95:1-9. 2009..These results indicate that the model presented is an appropriate tool for assessing glucose behavior during a FSIVGTT...
Lower adrenocortical and adrenomedullary responses to hypoglycemia in premenopausal women with systemic sclerosisRichard Imrich
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 833 06 Bratislava, Slovakia
J Rheumatol 33:2235-41. 2006..To evaluate function of the hypothalamic-pituitary-adrenal (HPA) axis, adrenomedullary hormonal system (AMHS), and sympathetic noradrenergic system (SNS) in premenopausal women with systemic sclerosis (SSc)...
Prolactin and growth hormone responses to hypoglycemia in patients with systemic sclerosis and psoriatic arthritisJozef Rovensky
National Institute of Rheumatic Diseases, Nabr I Krasku 4, 921 23 Piestany, Slovakia
Ann N Y Acad Sci 1069:145-8. 2006..PRL response tended to be lower also in PsA patients, however the difference did not reach level of statistical significance (P = 0.11). The present study showed decreased PRL response to hypoglycemia in premenopausal females with SSc...
