Eva Machová

Summary

Affiliation: Slovak Academy of Sciences
Country: Slovakia

Publications

  1. doi request reprint Importance of α- and β/α-linked mannooligosaccharides in antibody response against C. dubliniensis
    Izabela Medovarska
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38, Bratislava, Slovak Republic
    Glycoconj J 27:697-702. 2010
  2. doi request reprint Immune responsiveness of a novel peptidoglycan conjugate prepared from surface Candida immunogens: mannan and CR3-related protein
    Ema Paulovicova
    Center for Glycomics, Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia
    FEMS Immunol Med Microbiol 53:421-8. 2008
  3. ncbi request reprint Synthesis and immunogenicity of polysaccharide-protein conjugate composed of galactoglucoxylomannan of Cryptococcus laurentii
    Slavomir Bystricky
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 842 38 Bratislava, Slovakia
    FEMS Microbiol Lett 235:311-4. 2004
  4. ncbi request reprint Immune response to Saccharomyces cerevisiae mannan conjugate in mice
    Ema Paulovicova
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovakia
    Int Immunopharmacol 5:1693-8. 2005
  5. ncbi request reprint Cell and antibody mediated immunity induced by vaccination with novel Candida dubliniensis mannan immunogenic conjugate
    Ema Paulovicova
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovakia
    Int Immunopharmacol 7:1325-33. 2007
  6. ncbi request reprint Evaluation of different mannan polysaccharide usage in enzyme-linked immunosorbent assay for specific antibodies determination
    Lucia Libjaková
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 84538 Bratislava, Slovakia
    J Pharm Biomed Anal 45:521-5. 2007
  7. ncbi request reprint Growth inhibition of Candida albicans in the presence of antiserum elicited in rabbits by mannan-protein conjugate
    Eva Machová
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovak Republic
    Z Naturforsch C 63:909-12. 2008
  8. ncbi request reprint Candida albicans mannan-protein conjugate as vaccine candidate
    Slavomir Bystricky
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 842 38, Bratislava, Slovakia
    Immunol Lett 85:251-5. 2003
  9. doi request reprint Immunomodulation of T-cell responses with Vibrio cholerae O135 capsular polysaccharide and its protein conjugate, novel cholera vaccine study models
    Ema Paulovicova
    Slovak Academy of Sciences, Institute of Chemistry, Centre of Excellence GLYCOMED, Bratislava, Slovakia
    FEMS Immunol Med Microbiol 65:422-30. 2012
  10. ncbi request reprint Fungal chitin-glucan derivatives exert protective or damaging activity on plasmid DNA
    Grigorij Kogan
    Institute of Chemistry, Slovak Academy of Sciences, 845 38 Bratislava, Slovakia
    Carbohydr Res 338:931-5. 2003

Collaborators

Detail Information

Publications12

  1. doi request reprint Importance of α- and β/α-linked mannooligosaccharides in antibody response against C. dubliniensis
    Izabela Medovarska
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38, Bratislava, Slovak Republic
    Glycoconj J 27:697-702. 2010
    ..dubliniensis mannan may represent relevant points of interaction with host immune system during infection and b) anti-mannan antibodies induced by the two antigens (the mannan conjugate and the yeast) are of similar specificities...
  2. doi request reprint Immune responsiveness of a novel peptidoglycan conjugate prepared from surface Candida immunogens: mannan and CR3-related protein
    Ema Paulovicova
    Center for Glycomics, Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia
    FEMS Immunol Med Microbiol 53:421-8. 2008
    ..Altogether, it could be assumed that the novel peptide glycoconjugate is a prospective antigenic candidate for further Candida vaccine design...
  3. ncbi request reprint Synthesis and immunogenicity of polysaccharide-protein conjugate composed of galactoglucoxylomannan of Cryptococcus laurentii
    Slavomir Bystricky
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 842 38 Bratislava, Slovakia
    FEMS Microbiol Lett 235:311-4. 2004
    ..Effectiveness of immune serum to inhibit the growth of C. laurentii was demonstrated. The results indicate that the prepared conjugate could be considered as effective immunogen with potential for incorporation in the vaccine...
  4. ncbi request reprint Immune response to Saccharomyces cerevisiae mannan conjugate in mice
    Ema Paulovicova
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovakia
    Int Immunopharmacol 5:1693-8. 2005
    ..Newly synthesized S. cerevisiae mannan conjugate could be considered as a perspective vaccine candidate for preventive immunomodulation treatment...
  5. ncbi request reprint Cell and antibody mediated immunity induced by vaccination with novel Candida dubliniensis mannan immunogenic conjugate
    Ema Paulovicova
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovakia
    Int Immunopharmacol 7:1325-33. 2007
    ..Immunogenic effectiveness of mannan-HSA conjugate at a dose of 0.25 mg of mannan antigenic moiety overcame that of the mannan alone and of yeast whole cells, thus promising further application in Candida vaccine development...
  6. ncbi request reprint Evaluation of different mannan polysaccharide usage in enzyme-linked immunosorbent assay for specific antibodies determination
    Lucia Libjaková
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 84538 Bratislava, Slovakia
    J Pharm Biomed Anal 45:521-5. 2007
    ..008) efficiency. The use of protein cannot be avoided in normal microplates. All previous statements are supported by experimental data in the paper...
  7. ncbi request reprint Growth inhibition of Candida albicans in the presence of antiserum elicited in rabbits by mannan-protein conjugate
    Eva Machová
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovak Republic
    Z Naturforsch C 63:909-12. 2008
    ..No growth of treated cells on an agar plate was observed. The results confirmed that the mannan-protein conjugate could be considered as an effective component of perspective vaccine...
  8. ncbi request reprint Candida albicans mannan-protein conjugate as vaccine candidate
    Slavomir Bystricky
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 842 38, Bratislava, Slovakia
    Immunol Lett 85:251-5. 2003
    ..Anti-C. albicans effectiveness of immune serum is clearly demonstrated. Based on these results, the mannan conjugate synthesized by this scheme can be considered as actual vaccine candidate for clinical evaluation...
  9. doi request reprint Immunomodulation of T-cell responses with Vibrio cholerae O135 capsular polysaccharide and its protein conjugate, novel cholera vaccine study models
    Ema Paulovicova
    Slovak Academy of Sciences, Institute of Chemistry, Centre of Excellence GLYCOMED, Bratislava, Slovakia
    FEMS Immunol Med Microbiol 65:422-30. 2012
    ..The results revealed different T-cell antigen presentation and activation following administration of CPS and CPS-BSA conjugates, as supported also by evaluation of CD45, MHCII and CD25 expression on CD19(+) B cells...
  10. ncbi request reprint Fungal chitin-glucan derivatives exert protective or damaging activity on plasmid DNA
    Grigorij Kogan
    Institute of Chemistry, Slovak Academy of Sciences, 845 38 Bratislava, Slovakia
    Carbohydr Res 338:931-5. 2003
    ..However, process of DNA damaging induced by free-radical oxidation initiated with Fe(2+) was inhibited, while the process of DNA breakage induced by H(2)O(2) was increased in the presence of SE-Ch-G...
  11. doi request reprint Antioxidant capacities of mannans and glucans are related to their susceptibility of free radical degradation
    Eva Machová
    Institute of Chemistry, Department of Immunochemistry of Glycoconjugates, Centre of Excellence GLYCOMED, Slovak Academy of Sciences, Dubravska cesta 9, 84538 Bratislava, Slovakia Electronic address
    Int J Biol Macromol 61:308-11. 2013
    ..In all antioxidant and degradation experiments the yeast mannans showed very similar results to commercial β-glucans. The antioxidant capacities of polysaccharides may be assessed by simple HPLC monitoring...
  12. ncbi request reprint Preparation of a subcellular conjugate with the lipopolysaccharide from Vibrio cholerae 01 using beta-D-glucan as matrix
    Eva Machová
    Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 842 38 Bratislava, Slovakia
    Eur J Med Chem 37:681-7. 2002
    ..The obtained construct showed reactivity with the antibodies against V. cholerae and can serve as a prospective candidate for preparation of subcellular anti-cholera vaccine...